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The map label for this gene is yhcF [H]

Identifier: 226223365

GI number: 226223365

Start: 774031

End: 774408

Strand: Direct

Name: yhcF [H]

Synonym: Lm4b_00763

Alternate gene names: 226223365

Gene position: 774031-774408 (Clockwise)

Preceding gene: 226223363

Following gene: 226223366

Centisome position: 26.57

GC content: 32.8

Gene sequence:

>378_bases
ATGAAGTTTGATGATAGTAAACCCATTTATAAACAAATCGTTCATTATATTCATACAGAAATTGTTACAGGAATTTACAA
TGCTGGTGACAAGCTACTATCTGTAAGAGAGTTAGCAACAAAGTTAGAAGTAAATCCGACAACCATCCAGCGAGCTTATG
CAGAACTGGAAGAAACGGAAATTATTTACACCGTTCGAGGTACTGGTAAATATTTGACAGAAGATAAGAGGAGAATTGAG
CAATTGGAAAATGACATCGCAAAACAACTTACCGAAAATTTTATTAGTGAAATGAGTAAATTAGGAATTAATAAAGAAAA
AATTATCGCTTGGGTGAAAAAAGTAGAGGAGGTAGAAGTAAATGTTAGTGGGAAATAA

Upstream 100 bases:

>100_bases
AATGTATAAATGAAGCGATTTTCCTTTGATATAGTACATTCATAGCCAGTGTGACCCAGGTGGTACGGTGATACGGACAG
ACAGGCGAAAGGAGGAAATT

Downstream 100 bases:

>100_bases
TATCGCTAAATCCTATCCAAATAAATTAGTCTTACAAAATGTAGACCTCGAAGCAAAACCAGGCGACATGATCGTGCTCA
CTGGTGAAAATGGTAGCGGG

Product: transcriptional regulator (GntR family)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MKFDDSKPIYKQIVHYIHTEIVTGIYNAGDKLLSVRELATKLEVNPTTIQRAYAELEETEIIYTVRGTGKYLTEDKRRIE
QLENDIAKQLTENFISEMSKLGINKEKIIAWVKKVEEVEVNVSGK

Sequences:

>Translated_125_residues
MKFDDSKPIYKQIVHYIHTEIVTGIYNAGDKLLSVRELATKLEVNPTTIQRAYAELEETEIIYTVRGTGKYLTEDKRRIE
QLENDIAKQLTENFISEMSKLGINKEKIIAWVKKVEEVEVNVSGK
>Mature_125_residues
MKFDDSKPIYKQIVHYIHTEIVTGIYNAGDKLLSVRELATKLEVNPTTIQRAYAELEETEIIYTVRGTGKYLTEDKRRIE
QLENDIAKQLTENFISEMSKLGINKEKIIAWVKKVEEVEVNVSGK

Specific function: Possible Transcriptional Regulator Of The Succinyl-CoA- Synthetase Operon. Binds Specifically To The Farr Promoter And Exhibits Weak Binding To The Citrate Synthase And Lipoamide Dehydrogenase Promoters. Binding At The Farr Promoter Is Abolished By Long-

COG id: COG1725

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 14432; Mature: 14432

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDDSKPIYKQIVHYIHTEIVTGIYNAGDKLLSVRELATKLEVNPTTIQRAYAELEETE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCE
IIYTVRGTGKYLTEDKRRIEQLENDIAKQLTENFISEMSKLGINKEKIIAWVKKVEEVEV
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
NVSGK
CCCCC
>Mature Secondary Structure
MKFDDSKPIYKQIVHYIHTEIVTGIYNAGDKLLSVRELATKLEVNPTTIQRAYAELEETE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCE
IIYTVRGTGKYLTEDKRRIEQLENDIAKQLTENFISEMSKLGINKEKIIAWVKKVEEVEV
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
NVSGK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]