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The map label for this gene is fliY [H]

Identifier: 226223331

GI number: 226223331

Start: 741501

End: 743048

Strand: Direct

Name: fliY [H]

Synonym: Lm4b_00728

Alternate gene names: 226223331

Gene position: 741501-743048 (Clockwise)

Preceding gene: 226223330

Following gene: 226223332

Centisome position: 25.46

GC content: 39.92

Gene sequence:

>1548_bases
GTGGAGCAATTACTAGAGAAAAATATCACGCAAATGGAACTAGATGTGATAGGAGAAATCGCCAATATTTCGTTTGGCTC
AGCTTCTACGGTCTTATCTGATTTACTACACCAACAAGTCACCATTTCGACGCCAAAAGTTGAGATTGTTGATTTATATA
ATACGAAAGACATTGATATTCCACATGTCGTGTTAGAAGTGAATTTTCACAAAGGAATCGAAATGCGGAATTTATTTGTT
CTACAATCAGAAGTGGCTGCGGCTATCGCGGACTTAATGATGATGGGTGATGGAAACATTGATCCGAATGAAGAACTTTC
AGAACTTCATCTAAGCGCCGTACAAGAAGCGATGAACCAAATGATGGGACATTCCGCCACTGCAATGAGCAATATGTTTG
GCGAAATGATTGATATTACGACACCAGACATTAAAGTAATCGCGCTAAAAGAACAATTAGAAGATACGAACGACCAAACA
ATGATAAAAGTCGGCTTTGACTTAATTATCGGCGACTTGATCACATCGAATTTAATGCAACTCATCCCTATTGATAAAGG
GCATGAACTTGCAAAAAGATTACTTGGCGACGCAGTTCCAGAGCCAGAACCAGTAAAAGAAGAAATCAGCTTAACGGCCG
AAGAGTTAGATGTCTTTTTAGAAGTATGTAATATCGGCATCGGTTCAGCTTCAACCGTTCTATCCAAATTGCTTAACCGT
AAAGTTTCCTTACAAATCCCAACTGCACGCGTAATTGATAGCAAAGAGTTCGAGTTTAATGAACGTCCTTGCTTAGTGAC
GAGTGTGGAATTTGTCGAAGGGCTGCGCTCAAGCAACACATTTATCATTAGCAAAAATGCCGCGCTAATTATGGCAGATT
TAATGATGATGGGAGACGGTTTGGTTCAAGAAGATGCAGAACTGACGGAACTTGAAGTCAGCGCAGTGCAAGAATTAATG
AACCAGATGATGGGCTTCTCAGCGACAGCAATGTCAGAAATGCTCGGAACAAAAATCGATATTAGCCCACCTACAATGGA
ATTTTGTAATTTCGGCGATACGATGATTCAAAAAAACATTGAAGAAGGAAAAACTGTCGAAGTCATCTTCCCGCTAGAAG
TAGAAGGACTATTAAAAACGCCAATGTACCAAATTTTTAATCCAGCAGCAGCAAAAGAAATGGCGCAATTGATGCTTGGG
ATTCAGGCGAAAGAAGTCGCAGAGAAAGAAGCGACGACTCCAGCAGAAATAATCGAACCAGAAAAACTAGCTGAACCAGT
GCACCAAGCAGTTATCGAAGAAAAAGAAACACTTTCCGAAATGGAACAAATTTTGGAAGATATTCCCGTAACGCTTGAAG
TGGTATTCGGAACAGCAAAAGTAAAACTCGAAAAATTTATCTCTTGGTGTGAAAAAGATGTGATTATCCTAAAAGAGAGT
ATGAACGAACCACTTGTCTTAGCGCTAAATGGCGTGACGATTGGTAAAGGAATTTTAGTTCGCGTGGATGATCATTTTGG
TATACAAATGACGGAGTTAGTAAGGTGA

Upstream 100 bases:

>100_bases
CTGAAAAATGGAAATTTGAATGTTATATGGGAAAAAGTGGTAACCAAAAAGCCGTTAAATTTATGCGTCATACAGGGCGG
ACAGAGCAGGAGAGGTAGAA

Downstream 100 bases:

>100_bases
AAAATGTGCGGAAACTTGGACTGATGACAATTTTATTTTGGCTGTTTTTTTCGGTTCAAGCATTTGCAGCAGATCCTGAA
CCCCCGATAATATCGCTTGA

Product: flagellar motor switch protein

Products: NA

Alternate protein names: CheY-P phosphatase FliY [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MEQLLEKNITQMELDVIGEIANISFGSASTVLSDLLHQQVTISTPKVEIVDLYNTKDIDIPHVVLEVNFHKGIEMRNLFV
LQSEVAAAIADLMMMGDGNIDPNEELSELHLSAVQEAMNQMMGHSATAMSNMFGEMIDITTPDIKVIALKEQLEDTNDQT
MIKVGFDLIIGDLITSNLMQLIPIDKGHELAKRLLGDAVPEPEPVKEEISLTAEELDVFLEVCNIGIGSASTVLSKLLNR
KVSLQIPTARVIDSKEFEFNERPCLVTSVEFVEGLRSSNTFIISKNAALIMADLMMMGDGLVQEDAELTELEVSAVQELM
NQMMGFSATAMSEMLGTKIDISPPTMEFCNFGDTMIQKNIEEGKTVEVIFPLEVEGLLKTPMYQIFNPAAAKEMAQLMLG
IQAKEVAEKEATTPAEIIEPEKLAEPVHQAVIEEKETLSEMEQILEDIPVTLEVVFGTAKVKLEKFISWCEKDVIILKES
MNEPLVLALNGVTIGKGILVRVDDHFGIQMTELVR

Sequences:

>Translated_515_residues
MEQLLEKNITQMELDVIGEIANISFGSASTVLSDLLHQQVTISTPKVEIVDLYNTKDIDIPHVVLEVNFHKGIEMRNLFV
LQSEVAAAIADLMMMGDGNIDPNEELSELHLSAVQEAMNQMMGHSATAMSNMFGEMIDITTPDIKVIALKEQLEDTNDQT
MIKVGFDLIIGDLITSNLMQLIPIDKGHELAKRLLGDAVPEPEPVKEEISLTAEELDVFLEVCNIGIGSASTVLSKLLNR
KVSLQIPTARVIDSKEFEFNERPCLVTSVEFVEGLRSSNTFIISKNAALIMADLMMMGDGLVQEDAELTELEVSAVQELM
NQMMGFSATAMSEMLGTKIDISPPTMEFCNFGDTMIQKNIEEGKTVEVIFPLEVEGLLKTPMYQIFNPAAAKEMAQLMLG
IQAKEVAEKEATTPAEIIEPEKLAEPVHQAVIEEKETLSEMEQILEDIPVTLEVVFGTAKVKLEKFISWCEKDVIILKES
MNEPLVLALNGVTIGKGILVRVDDHFGIQMTELVR
>Mature_515_residues
MEQLLEKNITQMELDVIGEIANISFGSASTVLSDLLHQQVTISTPKVEIVDLYNTKDIDIPHVVLEVNFHKGIEMRNLFV
LQSEVAAAIADLMMMGDGNIDPNEELSELHLSAVQEAMNQMMGHSATAMSNMFGEMIDITTPDIKVIALKEQLEDTNDQT
MIKVGFDLIIGDLITSNLMQLIPIDKGHELAKRLLGDAVPEPEPVKEEISLTAEELDVFLEVCNIGIGSASTVLSKLLNR
KVSLQIPTARVIDSKEFEFNERPCLVTSVEFVEGLRSSNTFIISKNAALIMADLMMMGDGLVQEDAELTELEVSAVQELM
NQMMGFSATAMSEMLGTKIDISPPTMEFCNFGDTMIQKNIEEGKTVEVIFPLEVEGLLKTPMYQIFNPAAAKEMAQLMLG
IQAKEVAEKEATTPAEIIEPEKLAEPVHQAVIEEKETLSEMEQILEDIPVTLEVVFGTAKVKLEKFISWCEKDVIILKES
MNEPLVLALNGVTIGKGILVRVDDHFGIQMTELVR

Specific function: Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attr

COG id: COG1776

COG function: function code NT; Chemotaxis protein CheC, inhibitor of MCP methylation

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=The switch is localized at the base of the flagellar motor, in or near the C-ring, attached to the MS-ring (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FliN/MopA/SpaO family [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007597
- InterPro:   IPR012826
- InterPro:   IPR001172
- InterPro:   IPR001543 [H]

Pfam domain/function: PF04509 CheC; PF01052 SpoA [H]

EC number: NA

Molecular weight: Translated: 56927; Mature: 56927

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLLEKNITQMELDVIGEIANISFGSASTVLSDLLHQQVTISTPKVEIVDLYNTKDIDI
CCHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEECCCCEEEEEECCCCCCCC
PHVVLEVNFHKGIEMRNLFVLQSEVAAAIADLMMMGDGNIDPNEELSELHLSAVQEAMNQ
CEEEEEEECCCCCCHHHEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
MMGHSATAMSNMFGEMIDITTPDIKVIALKEQLEDTNDQTMIKVGFDLIIGDLITSNLMQ
HHCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHH
LIPIDKGHELAKRLLGDAVPEPEPVKEEISLTAEELDVFLEVCNIGIGSASTVLSKLLNR
HCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
KVSLQIPTARVIDSKEFEFNERPCLVTSVEFVEGLRSSNTFIISKNAALIMADLMMMGDG
CEEEECCCHHHCCCCCCCCCCCCEEEEEHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCC
LVQEDAELTELEVSAVQELMNQMMGFSATAMSEMLGTKIDISPPTMEFCNFGDTMIQKNI
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEECCCCCHHHHCCCHHHHHHHH
EEGKTVEVIFPLEVEGLLKTPMYQIFNPAAAKEMAQLMLGIQAKEVAEKEATTPAEIIEP
CCCCEEEEEEECCCCHHHHCCHHHHHCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHCCC
EKLAEPVHQAVIEEKETLSEMEQILEDIPVTLEVVFGTAKVKLEKFISWCEKDVIILKES
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCEEEEECC
MNEPLVLALNGVTIGKGILVRVDDHFGIQMTELVR
CCCCEEEEEECEEECCEEEEEECCCCCCCHHHHCC
>Mature Secondary Structure
MEQLLEKNITQMELDVIGEIANISFGSASTVLSDLLHQQVTISTPKVEIVDLYNTKDIDI
CCHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEECCCCEEEEEECCCCCCCC
PHVVLEVNFHKGIEMRNLFVLQSEVAAAIADLMMMGDGNIDPNEELSELHLSAVQEAMNQ
CEEEEEEECCCCCCHHHEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
MMGHSATAMSNMFGEMIDITTPDIKVIALKEQLEDTNDQTMIKVGFDLIIGDLITSNLMQ
HHCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHH
LIPIDKGHELAKRLLGDAVPEPEPVKEEISLTAEELDVFLEVCNIGIGSASTVLSKLLNR
HCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
KVSLQIPTARVIDSKEFEFNERPCLVTSVEFVEGLRSSNTFIISKNAALIMADLMMMGDG
CEEEECCCHHHCCCCCCCCCCCCEEEEEHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCC
LVQEDAELTELEVSAVQELMNQMMGFSATAMSEMLGTKIDISPPTMEFCNFGDTMIQKNI
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEECCCCCHHHHCCCHHHHHHHH
EEGKTVEVIFPLEVEGLLKTPMYQIFNPAAAKEMAQLMLGIQAKEVAEKEATTPAEIIEP
CCCCEEEEEEECCCCHHHHCCHHHHHCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHCCC
EKLAEPVHQAVIEEKETLSEMEQILEDIPVTLEVVFGTAKVKLEKFISWCEKDVIILKES
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCEEEEECC
MNEPLVLALNGVTIGKGILVRVDDHFGIQMTELVR
CCCCEEEEEECEEECCEEEEEECCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1447979; 9384377; 1898932 [H]