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The map label for this gene is pphA [H]

Identifier: 226223279

GI number: 226223279

Start: 694839

End: 695546

Strand: Direct

Name: pphA [H]

Synonym: Lm4b_00676

Alternate gene names: 226223279

Gene position: 694839-695546 (Clockwise)

Preceding gene: 226223278

Following gene: 226223281

Centisome position: 23.86

GC content: 41.24

Gene sequence:

>708_bases
ATGAAGCCAATTTTTGCTGTAGGAGATGTACACGGAGAGATTACGCTTTTAGATGAATTACTCGAAAACTGGGATAAAGA
GCAAGAACGGCTTTTGTTTGTAGGGGATTTGATTGACCGCGGCGAAAACCCAGCTGCAGTACTTAGAAGAGTGAAAGCAT
TAGCCGACCAAACGGGAGCGATTGTCTTAAAAGGAAATCACGAACAAATGTTACTAGATTTTCTCGAAAACCCTTCTGGG
AAAATGCATTATTATTTAAGTCAAGGCGGTATGGAAACAATTCAATCCTTAATCGCGGACTCGCTTGACAAAAAAATGAC
GCCGGAGGGACTTGCCGAACGGGTAAAAGAAGAAGCTGCTGAACTCATTGATTTCATCCGGAACTTGCCACTCTATTATG
AAGAAGGCAAATATGTATTTGTACATGCAGGCGTAGATTTGACGAAAAAAGATTGGCACGATACCGAGGAGCGTGATTTT
TTCTGGATTCGCGAACCTTTCTTATTTGGACAGAATAAAACCGGGAAAGTCTTTATTTTCGGGCATACCCCGGTACAAAA
TTTACATATTGATGAAAGTTCTGGTATTTGGGTTTCGGAAGATAAAACGAGGCTCGATATAGATGGTGGCGCGGTTTTTG
GCGGAGAACTTCACGGGGTTGTCGTGGAAGAAAAAGTCATCACGAAAAGTTTTTCTGTAAAAAAATAA

Upstream 100 bases:

>100_bases
AAAATCAAAAAAGCAGAAAGCAAAACCGAATAAGAAAAAAGCGTCCATTTGTTTATTTTGCAGAGGGGCGTTTCTTTTAC
GTAGATCTGGAGGTATAAGC

Downstream 100 bases:

>100_bases
GCATCGAATGGGCTCTTTTGAAGCGCTCATTCGATGCTTTTTTGTTTAATAATACGGTGCCATAAATAAGTAAACGAGTA
CGCCAGTTAAGCTGACATAT

Product: phosphoprotein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKPIFAVGDVHGEITLLDELLENWDKEQERLLFVGDLIDRGENPAAVLRRVKALADQTGAIVLKGNHEQMLLDFLENPSG
KMHYYLSQGGMETIQSLIADSLDKKMTPEGLAERVKEEAAELIDFIRNLPLYYEEGKYVFVHAGVDLTKKDWHDTEERDF
FWIREPFLFGQNKTGKVFIFGHTPVQNLHIDESSGIWVSEDKTRLDIDGGAVFGGELHGVVVEEKVITKSFSVKK

Sequences:

>Translated_235_residues
MKPIFAVGDVHGEITLLDELLENWDKEQERLLFVGDLIDRGENPAAVLRRVKALADQTGAIVLKGNHEQMLLDFLENPSG
KMHYYLSQGGMETIQSLIADSLDKKMTPEGLAERVKEEAAELIDFIRNLPLYYEEGKYVFVHAGVDLTKKDWHDTEERDF
FWIREPFLFGQNKTGKVFIFGHTPVQNLHIDESSGIWVSEDKTRLDIDGGAVFGGELHGVVVEEKVITKSFSVKK
>Mature_235_residues
MKPIFAVGDVHGEITLLDELLENWDKEQERLLFVGDLIDRGENPAAVLRRVKALADQTGAIVLKGNHEQMLLDFLENPSG
KMHYYLSQGGMETIQSLIADSLDKKMTPEGLAERVKEEAAELIDFIRNLPLYYEEGKYVFVHAGVDLTKKDWHDTEERDF
FWIREPFLFGQNKTGKVFIFGHTPVQNLHIDESSGIWVSEDKTRLDIDGGAVFGGELHGVVVEEKVITKSFSVKK

Specific function: Can hydrolyze phosphorylated Ser-, Thr- or Tyr- substrates in vitro. The natural substrate is unknown [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPP phosphatase family. PP-1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081988, Length=233, Percent_Identity=30.9012875536481, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 26647; Mature: 26647

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00125 SER_THR_PHOSPHATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIFAVGDVHGEITLLDELLENWDKEQERLLFVGDLIDRGENPAAVLRRVKALADQTGA
CCCEEEECCCCCHHHHHHHHHHHCCCHHHHEEEEEHHHHCCCCHHHHHHHHHHHHCCCCE
IVLKGNHEQMLLDFLENPSGKMHYYLSQGGMETIQSLIADSLDKKMTPEGLAERVKEEAA
EEEECCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ELIDFIRNLPLYYEEGKYVFVHAGVDLTKKDWHDTEERDFFWIREPFLFGQNKTGKVFIF
HHHHHHHCCCCEEECCCEEEEECCCCCCCCCCCCCCCCCEEEEECCEEECCCCCCEEEEE
GHTPVQNLHIDESSGIWVSEDKTRLDIDGGAVFGGELHGVVVEEKVITKSFSVKK
ECCCCCEEEEECCCCEEEECCCEEEEECCCEEECCCEEEEEEHHHHHHCCCCCCC
>Mature Secondary Structure
MKPIFAVGDVHGEITLLDELLENWDKEQERLLFVGDLIDRGENPAAVLRRVKALADQTGA
CCCEEEECCCCCHHHHHHHHHHHCCCHHHHEEEEEHHHHCCCCHHHHHHHHHHHHCCCCE
IVLKGNHEQMLLDFLENPSGKMHYYLSQGGMETIQSLIADSLDKKMTPEGLAERVKEEAA
EEEECCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ELIDFIRNLPLYYEEGKYVFVHAGVDLTKKDWHDTEERDFFWIREPFLFGQNKTGKVFIF
HHHHHHHCCCCEEECCCEEEEECCCCCCCCCCCCCCCCCEEEEECCEEECCCCCCEEEEE
GHTPVQNLHIDESSGIWVSEDKTRLDIDGGAVFGGELHGVVVEEKVITKSFSVKK
ECCCCCEEEEECCCCEEEECCCEEEEECCCEEECCCEEEEEEHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11717262; 11677609 [H]