Definition Listeria monocytogenes Clip81459, complete genome.
Accession NC_012488
Length 2,912,690

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The map label for this gene is yfnA [H]

Identifier: 226223269

GI number: 226223269

Start: 685020

End: 686411

Strand: Direct

Name: yfnA [H]

Synonym: Lm4b_00666

Alternate gene names: 226223269

Gene position: 685020-686411 (Clockwise)

Preceding gene: 226223267

Following gene: 226223270

Centisome position: 23.52

GC content: 38.94

Gene sequence:

>1392_bases
ATGAATTCATTATTTAGAAGAAAACCGATAGAAGATTTAATGCATAATAAAAGTGGTAGCACGCATTTAAAGCAAACGCT
CGGACCACTTGATTTAACTTTACTTGGAGTCGGAGCGATTGTTGGAACGGGGATTTTTATTTTACCGGGAACAGTCGCAG
CGAAAAATGCGGGACCAGCGATTATTTTCTCTTTTGTGATTGCGGCGATTGTTTGTGCGATTGCAGCAATGTGTTACTCA
GAGTTTGCGTCTAGTGTTCCGGTTGCAGGGAGCGCCTATACGTATGGTTATGTTGTTTTTGGCGAGTTAATTGGATGGTT
GCTTGGTTGGGCACTTATTTTAGAATACGGGCTTGCAGTGGCTTCTGTTGCGAGTGGGTGGTCTTCTTATTTAAATGCGT
TACTTTCAGGCTTTCATATTTCCATCCCAGAAGCAATCTCTGGGCCTTTTAATCCAGAAGTAGGTACATTTATTAATTTG
CCGGCGATTATTATTGTTCTTGTGATTGCCTTTTTATTGACGCTTGGGATAAAAGAATCAACGCGCGTGAATACCATTAT
GGTAGCTATTAAAGTTGGTGTTATTTTACTTTTCTTAGTTGTTGGTGTATTTTATGTCAAACCGGATAATTGGCAACCGT
TTATGCCATTTGGAATTAGTGGCGTTATGAATGGTGCGGCGCTAGTTTTCTTTGCTTATTTAGGTTTTGATGCCGTTTCG
TCTGCAGCTGAAGAAGTGAAAGATCCGCAACGGACAATGCCGATTGGGATTATAGGCTCGCTACTTATTTGTACGGTGTT
ATATGTTGCTGTATCCGCTGTTTTAACTGGAATGGTACCGTACACAGATTTAAACGTAACAGATCCAGTGGCTTATGCTT
TGCAAGTGATTAACCAAGATTGGGTAGCTGGCATTGTATCACTTGGCGCGGTTGTTGGGATGATTACAGTAATTTTAGTA
ATGAGTTACGGGGCGACTAGACTGATTTTTGCGATGGGACGTGATGGTTTATTACCAAAAGTACTTGCAGAAATTAATCA
AAAATATCAAACACCTGTTAAAAACACCTGGATTTTTGCAGTGATAGTCGCGATTATTAGTGGGCTTGTACCATTAGATC
GATTGGCTGAGTTGGTTAATATTGGAACACTCTTGGCGTTTATGATGGTGTCTATCGGGATTATCTTTTTACGTAAAAAT
AAAGATATTCAAGCGAGAGGATTTAAAGTACCATTTTACCCAGTTCTTCCAATTGTTTCGTTCTTATTATGTGCGTTTTT
AATTAGCCGTTTGTCTGTTCATACGTGGATTCTTTGCGGAATTTGGTTTGTTATTGGTTTAATTGTTTACTTTGCTTATG
GTAGAAAACATAGTGAGTTACTTAAAAAATAA

Upstream 100 bases:

>100_bases
GAAAGAATGATTAGTTTTTGTATTTTTTCTCACAATCCTATTGACCTTTAAAGTGTAAAAGGATATCCTTTTAGAAGACT
GTAAAAAGGTAGGAGACAAA

Downstream 100 bases:

>100_bases
TTAACTTACTTTTTGTAAGTCGTTTTATTGGAATTTGAACGCTCCTTATGTTGTAATGAATGTATTACAATAAAAGGAGC
GTTTTTTACATGGCAGAAAT

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MNSLFRRKPIEDLMHNKSGSTHLKQTLGPLDLTLLGVGAIVGTGIFILPGTVAAKNAGPAIIFSFVIAAIVCAIAAMCYS
EFASSVPVAGSAYTYGYVVFGELIGWLLGWALILEYGLAVASVASGWSSYLNALLSGFHISIPEAISGPFNPEVGTFINL
PAIIIVLVIAFLLTLGIKESTRVNTIMVAIKVGVILLFLVVGVFYVKPDNWQPFMPFGISGVMNGAALVFFAYLGFDAVS
SAAEEVKDPQRTMPIGIIGSLLICTVLYVAVSAVLTGMVPYTDLNVTDPVAYALQVINQDWVAGIVSLGAVVGMITVILV
MSYGATRLIFAMGRDGLLPKVLAEINQKYQTPVKNTWIFAVIVAIISGLVPLDRLAELVNIGTLLAFMMVSIGIIFLRKN
KDIQARGFKVPFYPVLPIVSFLLCAFLISRLSVHTWILCGIWFVIGLIVYFAYGRKHSELLKK

Sequences:

>Translated_463_residues
MNSLFRRKPIEDLMHNKSGSTHLKQTLGPLDLTLLGVGAIVGTGIFILPGTVAAKNAGPAIIFSFVIAAIVCAIAAMCYS
EFASSVPVAGSAYTYGYVVFGELIGWLLGWALILEYGLAVASVASGWSSYLNALLSGFHISIPEAISGPFNPEVGTFINL
PAIIIVLVIAFLLTLGIKESTRVNTIMVAIKVGVILLFLVVGVFYVKPDNWQPFMPFGISGVMNGAALVFFAYLGFDAVS
SAAEEVKDPQRTMPIGIIGSLLICTVLYVAVSAVLTGMVPYTDLNVTDPVAYALQVINQDWVAGIVSLGAVVGMITVILV
MSYGATRLIFAMGRDGLLPKVLAEINQKYQTPVKNTWIFAVIVAIISGLVPLDRLAELVNIGTLLAFMMVSIGIIFLRKN
KDIQARGFKVPFYPVLPIVSFLLCAFLISRLSVHTWILCGIWFVIGLIVYFAYGRKHSELLKK
>Mature_463_residues
MNSLFRRKPIEDLMHNKSGSTHLKQTLGPLDLTLLGVGAIVGTGIFILPGTVAAKNAGPAIIFSFVIAAIVCAIAAMCYS
EFASSVPVAGSAYTYGYVVFGELIGWLLGWALILEYGLAVASVASGWSSYLNALLSGFHISIPEAISGPFNPEVGTFINL
PAIIIVLVIAFLLTLGIKESTRVNTIMVAIKVGVILLFLVVGVFYVKPDNWQPFMPFGISGVMNGAALVFFAYLGFDAVS
SAAEEVKDPQRTMPIGIIGSLLICTVLYVAVSAVLTGMVPYTDLNVTDPVAYALQVINQDWVAGIVSLGAVVGMITVILV
MSYGATRLIFAMGRDGLLPKVLAEINQKYQTPVKNTWIFAVIVAIISGLVPLDRLAELVNIGTLLAFMMVSIGIIFLRKN
KDIQARGFKVPFYPVLPIVSFLLCAFLISRLSVHTWILCGIWFVIGLIVYFAYGRKHSELLKK

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=435, Percent_Identity=36.551724137931, Blast_Score=251, Evalue=8e-67,
Organism=Homo sapiens, GI110347453, Length=405, Percent_Identity=38.2716049382716, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI258614005, Length=429, Percent_Identity=35.4312354312354, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI258614003, Length=429, Percent_Identity=35.4312354312354, Blast_Score=245, Evalue=5e-65,
Organism=Homo sapiens, GI258645169, Length=429, Percent_Identity=35.4312354312354, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI181337167, Length=424, Percent_Identity=34.6698113207547, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI114326544, Length=436, Percent_Identity=36.0091743119266, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI114326550, Length=436, Percent_Identity=36.0091743119266, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI187423910, Length=464, Percent_Identity=24.5689655172414, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI7657591, Length=464, Percent_Identity=24.5689655172414, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI33286428, Length=458, Percent_Identity=28.1659388646288, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI115648063, Length=432, Percent_Identity=24.537037037037, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI115648022, Length=432, Percent_Identity=24.537037037037, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI71979932, Length=442, Percent_Identity=26.2443438914027, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI186910308, Length=448, Percent_Identity=24.5535714285714, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI186910306, Length=448, Percent_Identity=24.5535714285714, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI186910304, Length=448, Percent_Identity=24.5535714285714, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI7657683, Length=405, Percent_Identity=24.6913580246914, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI9790235, Length=305, Percent_Identity=23.6065573770492, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87081869, Length=444, Percent_Identity=24.5495495495495, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082023, Length=459, Percent_Identity=26.3616557734205, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786302, Length=424, Percent_Identity=22.6415094339623, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI2367353, Length=417, Percent_Identity=24.4604316546763, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788480, Length=441, Percent_Identity=22.6757369614512, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786789, Length=476, Percent_Identity=23.3193277310924, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87082250, Length=354, Percent_Identity=27.4011299435028, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI87081708, Length=444, Percent_Identity=20.045045045045, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786694, Length=404, Percent_Identity=25, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786602, Length=474, Percent_Identity=20.6751054852321, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789017, Length=460, Percent_Identity=20.6521739130435, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786908, Length=361, Percent_Identity=23.2686980609418, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790575, Length=319, Percent_Identity=23.8244514106583, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790653, Length=356, Percent_Identity=21.6292134831461, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=390, Percent_Identity=38.4615384615385, Blast_Score=269, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI17531343, Length=404, Percent_Identity=36.6336633663366, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17533459, Length=412, Percent_Identity=35.9223300970874, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17568033, Length=439, Percent_Identity=23.0068337129841, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17537453, Length=347, Percent_Identity=25.3602305475504, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193208714, Length=416, Percent_Identity=21.6346153846154, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32566695, Length=422, Percent_Identity=21.8009478672986, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71982612, Length=409, Percent_Identity=21.2713936430318, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71982608, Length=409, Percent_Identity=21.2713936430318, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=319, Percent_Identity=24.7648902821317, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17540018, Length=425, Percent_Identity=25.1764705882353, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71993915, Length=395, Percent_Identity=21.7721518987342, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71995382, Length=395, Percent_Identity=23.7974683544304, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71995388, Length=395, Percent_Identity=23.2911392405063, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24666159, Length=413, Percent_Identity=38.0145278450363, Blast_Score=295, Evalue=6e-80,
Organism=Drosophila melanogaster, GI221512776, Length=413, Percent_Identity=38.0145278450363, Blast_Score=295, Evalue=6e-80,
Organism=Drosophila melanogaster, GI24668806, Length=412, Percent_Identity=37.378640776699, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI21356285, Length=412, Percent_Identity=37.378640776699, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24668802, Length=412, Percent_Identity=37.378640776699, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24667468, Length=384, Percent_Identity=36.9791666666667, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI281366235, Length=412, Percent_Identity=34.9514563106796, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI116007820, Length=412, Percent_Identity=34.9514563106796, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI116007818, Length=412, Percent_Identity=34.9514563106796, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI85725152, Length=412, Percent_Identity=34.9514563106796, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI161077963, Length=406, Percent_Identity=33.9901477832512, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI21357367, Length=447, Percent_Identity=23.0425055928412, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI221331183, Length=454, Percent_Identity=25.5506607929515, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17647653, Length=454, Percent_Identity=25.5506607929515, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24664379, Length=454, Percent_Identity=25.5506607929515, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI45550968, Length=465, Percent_Identity=24.5161290322581, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19921172, Length=465, Percent_Identity=24.5161290322581, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24651635, Length=417, Percent_Identity=23.5011990407674, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24651633, Length=417, Percent_Identity=23.5011990407674, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24641995, Length=430, Percent_Identity=20.9302325581395, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641993, Length=430, Percent_Identity=20.9302325581395, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49836; Mature: 49836

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNSLFRRKPIEDLMHNKSGSTHLKQTLGPLDLTLLGVGAIVGTGIFILPGTVAAKNAGPA
CCCCHHCCCHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCHHEECCCHHCCCCCHH
IIFSFVIAAIVCAIAAMCYSEFASSVPVAGSAYTYGYVVFGELIGWLLGWALILEYGLAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVASGWSSYLNALLSGFHISIPEAISGPFNPEVGTFINLPAIIIVLVIAFLLTLGIKES
HHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
TRVNTIMVAIKVGVILLFLVVGVFYVKPDNWQPFMPFGISGVMNGAALVFFAYLGFDAVS
CHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SAAEEVKDPQRTMPIGIIGSLLICTVLYVAVSAVLTGMVPYTDLNVTDPVAYALQVINQD
HHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
WVAGIVSLGAVVGMITVILVMSYGATRLIFAMGRDGLLPKVLAEINQKYQTPVKNTWIFA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHH
VIVAIISGLVPLDRLAELVNIGTLLAFMMVSIGIIFLRKNKDIQARGFKVPFYPVLPIVS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHH
FLLCAFLISRLSVHTWILCGIWFVIGLIVYFAYGRKHSELLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
>Mature Secondary Structure
MNSLFRRKPIEDLMHNKSGSTHLKQTLGPLDLTLLGVGAIVGTGIFILPGTVAAKNAGPA
CCCCHHCCCHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCHHEECCCHHCCCCCHH
IIFSFVIAAIVCAIAAMCYSEFASSVPVAGSAYTYGYVVFGELIGWLLGWALILEYGLAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVASGWSSYLNALLSGFHISIPEAISGPFNPEVGTFINLPAIIIVLVIAFLLTLGIKES
HHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
TRVNTIMVAIKVGVILLFLVVGVFYVKPDNWQPFMPFGISGVMNGAALVFFAYLGFDAVS
CHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SAAEEVKDPQRTMPIGIIGSLLICTVLYVAVSAVLTGMVPYTDLNVTDPVAYALQVINQD
HHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
WVAGIVSLGAVVGMITVILVMSYGATRLIFAMGRDGLLPKVLAEINQKYQTPVKNTWIFA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHH
VIVAIISGLVPLDRLAELVNIGTLLAFMMVSIGIIFLRKNKDIQARGFKVPFYPVLPIVS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHH
FLLCAFLISRLSVHTWILCGIWFVIGLIVYFAYGRKHSELLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]