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The map label for this gene is yybE [H]

Identifier: 226223114

GI number: 226223114

Start: 521086

End: 521979

Strand: Reverse

Name: yybE [H]

Synonym: Lm4b_00511

Alternate gene names: 226223114

Gene position: 521979-521086 (Counterclockwise)

Preceding gene: 226223118

Following gene: 226223099

Centisome position: 17.92

GC content: 38.14

Gene sequence:

>894_bases
ATGAATTTGCGTCAATTATACTATTTTAAAAAACTAGCTGAAAAAGAGCATTACACGATCGCAGCCGCCGAACTCTCCAT
TACCCAGCCTAGCTTAAGCCATTCTATCGCAGAACTTGAGCGAGAACTTGGTGTCTATTTATTTGAAAAACAAGGCCGCA
ATATTCGTTTAACTAAATACGGTCGCTTTTATTTAACTTATGTGGAAAAATCCCTCGCCGAACTAGAAAAAGGTGAAAAA
CTTTTACACGAATTAACGAGCCCATCGCACGGAAATATTGATTTAGGGTTTATTTACACCATGGGCGCCCATACGGTTCC
AGAGCTCGTCCAGAATTTCACCAAAGTCGAAAGCCATAAAGACATCACATTTTCCTTTTTCCAAGGTGCCACTAAATCAA
TTATCCCTGATTTAAAAAATGAAAAATTCGACCTAGCGATTTGCTCCTACGTCGAAAATGAACCTGATATTGAGTTTTTA
CCATTAACAAAACAAGAGTTAGTTGTTGTCGTTGCCGAAAACCACCCACTTGCCAAACATGATTCGATTGATTTAAAAGA
CACCGCAGATTATTCGTATATTTTCTTTTCTGACACCAGTGGGCTGAGACCGCTTATTGATTCTCTTTTTGCGGAAATAA
ATATTCAACCTAAAATCGGCTGTTATGTAGAGGAGGATACCGCAATGGTTGGGCTTGTGAGTGTTGATTACGGTATTTCT
ATCATGCCAAAAATCTCCTCATTAGCACACTACAATGTCAAAGTATTATCCATCAACGAACCAAAACACGATCGTTTTAT
CTATCTAGCAAGTTTGAAAAACCACTACATTTCGCCTGCTTCCAAGGCTTTTAAAGATTTCGCATTACGTTATGGTAAAA
AGCATTTCCTATAA

Upstream 100 bases:

>100_bases
ATAATTATTAATCTAATGTATATTTTTCGATTTATCCATAGATTTTTTCTATACAATCGCTTACAATAGAGTTATCAAGG
CATTCCGAGGAGGTAGTTTC

Downstream 100 bases:

>100_bases
AAAAAGGAGCCAACCAAATCGGTGGCTCCTTTTCTATTAAAAATAAATACTTCCTGCTTCAGCATCCGCATTAAATCGGT
ATAACTCACCAACTTTTTCT

Product: transcriptional regulator (LysR family)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNLRQLYYFKKLAEKEHYTIAAAELSITQPSLSHSIAELERELGVYLFEKQGRNIRLTKYGRFYLTYVEKSLAELEKGEK
LLHELTSPSHGNIDLGFIYTMGAHTVPELVQNFTKVESHKDITFSFFQGATKSIIPDLKNEKFDLAICSYVENEPDIEFL
PLTKQELVVVVAENHPLAKHDSIDLKDTADYSYIFFSDTSGLRPLIDSLFAEINIQPKIGCYVEEDTAMVGLVSVDYGIS
IMPKISSLAHYNVKVLSINEPKHDRFIYLASLKNHYISPASKAFKDFALRYGKKHFL

Sequences:

>Translated_297_residues
MNLRQLYYFKKLAEKEHYTIAAAELSITQPSLSHSIAELERELGVYLFEKQGRNIRLTKYGRFYLTYVEKSLAELEKGEK
LLHELTSPSHGNIDLGFIYTMGAHTVPELVQNFTKVESHKDITFSFFQGATKSIIPDLKNEKFDLAICSYVENEPDIEFL
PLTKQELVVVVAENHPLAKHDSIDLKDTADYSYIFFSDTSGLRPLIDSLFAEINIQPKIGCYVEEDTAMVGLVSVDYGIS
IMPKISSLAHYNVKVLSINEPKHDRFIYLASLKNHYISPASKAFKDFALRYGKKHFL
>Mature_297_residues
MNLRQLYYFKKLAEKEHYTIAAAELSITQPSLSHSIAELERELGVYLFEKQGRNIRLTKYGRFYLTYVEKSLAELEKGEK
LLHELTSPSHGNIDLGFIYTMGAHTVPELVQNFTKVESHKDITFSFFQGATKSIIPDLKNEKFDLAICSYVENEPDIEFL
PLTKQELVVVVAENHPLAKHDSIDLKDTADYSYIFFSDTSGLRPLIDSLFAEINIQPKIGCYVEEDTAMVGLVSVDYGIS
IMPKISSLAHYNVKVLSINEPKHDRFIYLASLKNHYISPASKAFKDFALRYGKKHFL

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=28.3216783216783, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787879, Length=289, Percent_Identity=25.9515570934256, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790399, Length=278, Percent_Identity=26.2589928057554, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=25.6055363321799, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788887, Length=247, Percent_Identity=26.7206477732794, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788748, Length=295, Percent_Identity=23.728813559322, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788296, Length=245, Percent_Identity=24.4897959183673, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788297, Length=292, Percent_Identity=22.9452054794521, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787530, Length=249, Percent_Identity=21.6867469879518, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787601, Length=246, Percent_Identity=23.1707317073171, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367136, Length=243, Percent_Identity=23.8683127572016, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787806, Length=264, Percent_Identity=23.8636363636364, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789204, Length=248, Percent_Identity=22.5806451612903, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081904, Length=239, Percent_Identity=23.0125523012552, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=23.5494880546075, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790262, Length=243, Percent_Identity=21.3991769547325, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790208, Length=248, Percent_Identity=22.9838709677419, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33901; Mature: 33901

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRQLYYFKKLAEKEHYTIAAAELSITQPSLSHSIAELERELGVYLFEKQGRNIRLTKY
CCHHHHHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCEEEEECCCCEEEEEEE
GRFYLTYVEKSLAELEKGEKLLHELTSPSHGNIDLGFIYTMGAHTVPELVQNFTKVESHK
CCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCC
DITFSFFQGATKSIIPDLKNEKFDLAICSYVENEPDIEFLPLTKQELVVVVAENHPLAKH
CEEEHHHHCCHHHHCCCCCCCCEEEEEEEHHCCCCCEEEEECCCCCEEEEEECCCCCCCC
DSIDLKDTADYSYIFFSDTSGLRPLIDSLFAEINIQPKIGCYVEEDTAMVGLVSVDYGIS
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEECCCCE
IMPKISSLAHYNVKVLSINEPKHDRFIYLASLKNHYISPASKAFKDFALRYGKKHFL
ECCCHHHHCCCEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLRQLYYFKKLAEKEHYTIAAAELSITQPSLSHSIAELERELGVYLFEKQGRNIRLTKY
CCHHHHHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCEEEEECCCCEEEEEEE
GRFYLTYVEKSLAELEKGEKLLHELTSPSHGNIDLGFIYTMGAHTVPELVQNFTKVESHK
CCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCC
DITFSFFQGATKSIIPDLKNEKFDLAICSYVENEPDIEFLPLTKQELVVVVAENHPLAKH
CEEEHHHHCCHHHHCCCCCCCCEEEEEEEHHCCCCCEEEEECCCCCEEEEEECCCCCCCC
DSIDLKDTADYSYIFFSDTSGLRPLIDSLFAEINIQPKIGCYVEEDTAMVGLVSVDYGIS
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEECCCCE
IMPKISSLAHYNVKVLSINEPKHDRFIYLASLKNHYISPASKAFKDFALRYGKKHFL
ECCCHHHHCCCEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]