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The map label for this gene is iolC [H]

Identifier: 226223010

GI number: 226223010

Start: 410364

End: 411341

Strand: Direct

Name: iolC [H]

Synonym: Lm4b_00403

Alternate gene names: 226223010

Gene position: 410364-411341 (Clockwise)

Preceding gene: 226223009

Following gene: 226223011

Centisome position: 14.09

GC content: 41.92

Gene sequence:

>978_bases
ATGAATCTAAACAAACATAGCGAACGAAAATTTGATTTAATCACAGTAGGACGCGCTTGTATTGATTTGAACGCAGTCGA
ATACAATCGTCCAATGGAAGAAACGATGACTTTTTCTAAATATGTGGGTGGTTCCCCGGCAAATATTGCGATAGGAACCG
CAAAACTAGGCTTAAAAGTAGGCTTTATCGGCAAAATTTCTGCTGATCAACATGGTCGTTTTATTGAGAAATATATGCGT
GATTTGAGTATAAATACGGACGGAATGGTGAAAGATACGGAAGGCCGCAAAGTTGGCTTGGCGTTTACGGAAATTAAAAG
CCCAGATGAATGCAGTATTTTGATGTATCGCGAAAATGTAGCGGATTTGTATTTAACGCCAGAAGAAATTTCGGAAGATT
ATATAAAAGAGGCTCGCGTGCTGCTCATTTCTGGAACAGCTTTAGCGCAAAGTCCATCGCGGGAAGCTGTTTTAAAGGCA
GTTAGTTTAGCTCGGAAAAATGATGTAGCCGTTGCTTTTGAATTAGATTATCGCCCTTATACGTGGACAAACACCGAAGA
AACGGCGGTTTATTATTCACTTGTCGCAGAACAAGCGGATGTGATTATTGGCACGCGCGACGAATTTGATATGATGGAAA
ATCAAGTCGGTGGCAAAAATGAAGCAACAAAAGCGCATCTTTTCCAACATCAAGCAGAAATTGTTGTCATTAAGCATGGG
GTGGAAGGCTCATTCGCATATACAAAAGCGGGAGAAACATTCCAAGCAAAAGCATATAAAACAAAAGTGCTCAAAACATT
CGGCGCGGGAGATTCCTACGCATCAGCCTTCTTATACGGTTTATTTAGCGGTGAAAGTATCGAAACAGCCCTTAAATACG
GAAGTGCCGCGGCTTCGATTGTTGTTAGCAAGCATAGTTCCTCAGACGCGATGCCAACAGCTGATGAAATCAAAGCGCTC
ATTGCGCAAGCGGAATAG

Upstream 100 bases:

>100_bases
TATTTGAACGTAATGGCTGGACCGAAACGGGTTTGGAAATTTCACAACGATCCGGACCATGAATGGATTTTAGAACGAGA
CTAAGAGGAGGATTTGGAGC

Downstream 100 bases:

>100_bases
GAGGAGATTATGGTGACTGAAAAAACGATTCGACTAACAACCGCACAAGCTTTGGTAAAATTTTTAAATCAGCAATATAT
CGAAGTGGACGGCGAAATGG

Product: IolC protein and to fructokinase

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MNLNKHSERKFDLITVGRACIDLNAVEYNRPMEETMTFSKYVGGSPANIAIGTAKLGLKVGFIGKISADQHGRFIEKYMR
DLSINTDGMVKDTEGRKVGLAFTEIKSPDECSILMYRENVADLYLTPEEISEDYIKEARVLLISGTALAQSPSREAVLKA
VSLARKNDVAVAFELDYRPYTWTNTEETAVYYSLVAEQADVIIGTRDEFDMMENQVGGKNEATKAHLFQHQAEIVVIKHG
VEGSFAYTKAGETFQAKAYKTKVLKTFGAGDSYASAFLYGLFSGESIETALKYGSAAASIVVSKHSSSDAMPTADEIKAL
IAQAE

Sequences:

>Translated_325_residues
MNLNKHSERKFDLITVGRACIDLNAVEYNRPMEETMTFSKYVGGSPANIAIGTAKLGLKVGFIGKISADQHGRFIEKYMR
DLSINTDGMVKDTEGRKVGLAFTEIKSPDECSILMYRENVADLYLTPEEISEDYIKEARVLLISGTALAQSPSREAVLKA
VSLARKNDVAVAFELDYRPYTWTNTEETAVYYSLVAEQADVIIGTRDEFDMMENQVGGKNEATKAHLFQHQAEIVVIKHG
VEGSFAYTKAGETFQAKAYKTKVLKTFGAGDSYASAFLYGLFSGESIETALKYGSAAASIVVSKHSSSDAMPTADEIKAL
IAQAE
>Mature_325_residues
MNLNKHSERKFDLITVGRACIDLNAVEYNRPMEETMTFSKYVGGSPANIAIGTAKLGLKVGFIGKISADQHGRFIEKYMR
DLSINTDGMVKDTEGRKVGLAFTEIKSPDECSILMYRENVADLYLTPEEISEDYIKEARVLLISGTALAQSPSREAVLKA
VSLARKNDVAVAFELDYRPYTWTNTEETAVYYSLVAEQADVIIGTRDEFDMMENQVGGKNEATKAHLFQHQAEIVVIKHG
VEGSFAYTKAGETFQAKAYKTKVLKTFGAGDSYASAFLYGLFSGESIETALKYGSAAASIVVSKHSSSDAMPTADEIKAL
IAQAE

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87082281, Length=287, Percent_Identity=28.2229965156794, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 35644; Mature: 35644

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNKHSERKFDLITVGRACIDLNAVEYNRPMEETMTFSKYVGGSPANIAIGTAKLGLKV
CCCCCCCCCCEEEEEECHHHEECCHHHCCCCHHHHHHHHHHCCCCCCEEEEEEEEEEEEE
GFIGKISADQHGRFIEKYMRDLSINTDGMVKDTEGRKVGLAFTEIKSPDECSILMYRENV
EEEEECCCCCCHHHHHHHHHHCCCCCCCCEECCCCCEEEEEEEECCCCCCCEEEEEECCC
ADLYLTPEEISEDYIKEARVLLISGTALAQSPSREAVLKAVSLARKNDVAVAFELDYRPY
CEEEECHHHHHHHHHHCCEEEEEECCHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCC
TWTNTEETAVYYSLVAEQADVIIGTRDEFDMMENQVGGKNEATKAHLFQHQAEIVVIKHG
EECCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEC
VEGSFAYTKAGETFQAKAYKTKVLKTFGAGDSYASAFLYGLFSGESIETALKYGSAAASI
CCCCEEEECCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEE
VVSKHSSSDAMPTADEIKALIAQAE
EEEECCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNLNKHSERKFDLITVGRACIDLNAVEYNRPMEETMTFSKYVGGSPANIAIGTAKLGLKV
CCCCCCCCCCEEEEEECHHHEECCHHHCCCCHHHHHHHHHHCCCCCCEEEEEEEEEEEEE
GFIGKISADQHGRFIEKYMRDLSINTDGMVKDTEGRKVGLAFTEIKSPDECSILMYRENV
EEEEECCCCCCHHHHHHHHHHCCCCCCCCEECCCCCEEEEEEEECCCCCCCEEEEEECCC
ADLYLTPEEISEDYIKEARVLLISGTALAQSPSREAVLKAVSLARKNDVAVAFELDYRPY
CEEEECHHHHHHHHHHCCEEEEEECCHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCC
TWTNTEETAVYYSLVAEQADVIIGTRDEFDMMENQVGGKNEATKAHLFQHQAEIVVIKHG
EECCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEC
VEGSFAYTKAGETFQAKAYKTKVLKTFGAGDSYASAFLYGLFSGESIETALKYGSAAASI
CCCCEEEECCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEE
VVSKHSSSDAMPTADEIKALIAQAE
EEEECCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]