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The map label for this gene is licC [H]

Identifier: 226223000

GI number: 226223000

Start: 401593

End: 402927

Strand: Direct

Name: licC [H]

Synonym: Lm4b_00392

Alternate gene names: 226223000

Gene position: 401593-402927 (Clockwise)

Preceding gene: 226222999

Following gene: 226223001

Centisome position: 13.79

GC content: 39.25

Gene sequence:

>1335_bases
ATGGCTGAAACGAAAAAGAAGTCGATTGTTAATGGATTTATTAATGTAGCACAACGTCTTGGTGGTCAGATTCATTTGCG
TTCATTGCGTGATGCTTTTGCGAGTATTATGCCGTTCATGATTTTAGCTGGTTTTGTCACGCTGATTAACTATGTTATTT
TAGAACCGACTGGCTTTATGGGCAAAATTGTTAACCCAGATACACTTAAAACATGGCAAGAGATTGGTATTTCAATCGGA
AATGGTACGCTGAGTGTTATTACGCTTTTAGTCACTGTGGCGATTTCGTATCATTTATGTTTGAACCGCGGCTATAAAAA
CGTTATTGCTCCAATTCTTGTTGCCTTATCTTCATTTATCGTCGTAACACCGATTGCAACGACCTTCCTTCCAGAAGGCG
CATCAAAATCAATCGAAGTACCGAACGTTATCCCAGTTAGTTATACTGGCGCGTCAGGCATGTTCGTCGGTATTATCGTT
GGTTTAATTGCAACCGATTTATTCATTAAATTATCGAAAAACAAACGTATGCAAATCAATTTAACAGGAAATATTCCACC
GGCAGTTATTAAATCATTTAACGTGTTAATTCCGATTATGATTACGGTTATTATTTTCTCAGTTATGTCATTTGCCGTTA
ACCAAATTTTCAGCATGGACTTTAATACACTTGTGACAACGATTATCACGAAGCCGCTTAGCTATGTGACGACAAGTCTT
CCAGGGTTCTTGCTGATTACTTCTATCGCTAACTTATTCTTCGGTTTGGGGATTCATCAAGCAGTTATTTCTGGTCCGTT
ACTAGATCCATTTTTACTTCAAAATATGCAAGAAAACATGGTAGCCTACGCGAATCATCAAGAAATTCCGCATATTATTA
ACATGGCTTTCAAAGACACATTTGCGGTTATGGGTGGCTCAGGAAACACGATTGGCTTATTAATTGCCATTTTCATCTTT
GGGAAACGAAAAGATTACAAAGATATCTCGAAACTATCTGCGGCACCATCACTATTTAACATCAGTGAGCCAATCATCTT
TGGTCTGCCGATTGTGTTCAACCCGTTACTTATTATCCCGTTCGTATTAGCGCCAATTTTCTCCTTAACAACAGCGTATT
TTGCGACAGCAGCAGGTTGGATTAATCATGTAGTCGTACAAACACCGTGGACGACACCGCCGATTATTTCTGGTTTCCTA
GCAACTGGCGGGGACTGGCGCGCGTCCGTTTTACAAGTAATTATCATTGTTGTGACGGTCTTTATCTATCTGCCGTTCCT
ACGTATGGATGAAAAAGTTGCTTTTGCTACAGCTCAAAAAACAGAAGCAAAATAA

Upstream 100 bases:

>100_bases
ATGAAGAAAAGTGGCGAACTTTATAAAAAAATGAGTGACATGAACGGTTTTGAATATGATACAAGCAAACTAGTTGGGAC
GAAAAGGGAGGAAACAACTA

Downstream 100 bases:

>100_bases
GGAAGGAAGTTTAACCAATGAAAAACATTTTATTAGTATGTAATGCTGGTATGTCCACAAGTTTCTTAGTAGAAAAAATG
AAAGCAGCAGGCGCGGAACA

Product: PTS betaglucoside-specific enzyme IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAETKKKSIVNGFINVAQRLGGQIHLRSLRDAFASIMPFMILAGFVTLINYVILEPTGFMGKIVNPDTLKTWQEIGISIG
NGTLSVITLLVTVAISYHLCLNRGYKNVIAPILVALSSFIVVTPIATTFLPEGASKSIEVPNVIPVSYTGASGMFVGIIV
GLIATDLFIKLSKNKRMQINLTGNIPPAVIKSFNVLIPIMITVIIFSVMSFAVNQIFSMDFNTLVTTIITKPLSYVTTSL
PGFLLITSIANLFFGLGIHQAVISGPLLDPFLLQNMQENMVAYANHQEIPHIINMAFKDTFAVMGGSGNTIGLLIAIFIF
GKRKDYKDISKLSAAPSLFNISEPIIFGLPIVFNPLLIIPFVLAPIFSLTTAYFATAAGWINHVVVQTPWTTPPIISGFL
ATGGDWRASVLQVIIIVVTVFIYLPFLRMDEKVAFATAQKTEAK

Sequences:

>Translated_444_residues
MAETKKKSIVNGFINVAQRLGGQIHLRSLRDAFASIMPFMILAGFVTLINYVILEPTGFMGKIVNPDTLKTWQEIGISIG
NGTLSVITLLVTVAISYHLCLNRGYKNVIAPILVALSSFIVVTPIATTFLPEGASKSIEVPNVIPVSYTGASGMFVGIIV
GLIATDLFIKLSKNKRMQINLTGNIPPAVIKSFNVLIPIMITVIIFSVMSFAVNQIFSMDFNTLVTTIITKPLSYVTTSL
PGFLLITSIANLFFGLGIHQAVISGPLLDPFLLQNMQENMVAYANHQEIPHIINMAFKDTFAVMGGSGNTIGLLIAIFIF
GKRKDYKDISKLSAAPSLFNISEPIIFGLPIVFNPLLIIPFVLAPIFSLTTAYFATAAGWINHVVVQTPWTTPPIISGFL
ATGGDWRASVLQVIIIVVTVFIYLPFLRMDEKVAFATAQKTEAK
>Mature_443_residues
AETKKKSIVNGFINVAQRLGGQIHLRSLRDAFASIMPFMILAGFVTLINYVILEPTGFMGKIVNPDTLKTWQEIGISIGN
GTLSVITLLVTVAISYHLCLNRGYKNVIAPILVALSSFIVVTPIATTFLPEGASKSIEVPNVIPVSYTGASGMFVGIIVG
LIATDLFIKLSKNKRMQINLTGNIPPAVIKSFNVLIPIMITVIIFSVMSFAVNQIFSMDFNTLVTTIITKPLSYVTTSLP
GFLLITSIANLFFGLGIHQAVISGPLLDPFLLQNMQENMVAYANHQEIPHIINMAFKDTFAVMGGSGNTIGLLIAIFIFG
KRKDYKDISKLSAAPSLFNISEPIIFGLPIVFNPLLIIPFVLAPIFSLTTAYFATAAGWINHVVVQTPWTTPPIISGFLA
TGGDWRASVLQVIIIVVTVFIYLPFLRMDEKVAFATAQKTEAK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=448, Percent_Identity=28.7946428571429, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 48273; Mature: 48142

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETKKKSIVNGFINVAQRLGGQIHLRSLRDAFASIMPFMILAGFVTLINYVILEPTGFM
CCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GKIVNPDTLKTWQEIGISIGNGTLSVITLLVTVAISYHLCLNRGYKNVIAPILVALSSFI
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VVTPIATTFLPEGASKSIEVPNVIPVSYTGASGMFVGIIVGLIATDLFIKLSKNKRMQIN
HHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCEEEEE
LTGNIPPAVIKSFNVLIPIMITVIIFSVMSFAVNQIFSMDFNTLVTTIITKPLSYVTTSL
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
PGFLLITSIANLFFGLGIHQAVISGPLLDPFLLQNMQENMVAYANHQEIPHIINMAFKDT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
FAVMGGSGNTIGLLIAIFIFGKRKDYKDISKLSAAPSLFNISEPIIFGLPIVFNPLLIIP
HHEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHHH
FVLAPIFSLTTAYFATAAGWINHVVVQTPWTTPPIISGFLATGGDWRASVLQVIIIVVTV
HHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
FIYLPFLRMDEKVAFATAQKTEAK
HHHHHHHHCCCHHHHHCCHHCCCC
>Mature Secondary Structure 
AETKKKSIVNGFINVAQRLGGQIHLRSLRDAFASIMPFMILAGFVTLINYVILEPTGFM
CCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GKIVNPDTLKTWQEIGISIGNGTLSVITLLVTVAISYHLCLNRGYKNVIAPILVALSSFI
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VVTPIATTFLPEGASKSIEVPNVIPVSYTGASGMFVGIIVGLIATDLFIKLSKNKRMQIN
HHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCEEEEE
LTGNIPPAVIKSFNVLIPIMITVIIFSVMSFAVNQIFSMDFNTLVTTIITKPLSYVTTSL
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
PGFLLITSIANLFFGLGIHQAVISGPLLDPFLLQNMQENMVAYANHQEIPHIINMAFKDT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
FAVMGGSGNTIGLLIAIFIFGKRKDYKDISKLSAAPSLFNISEPIIFGLPIVFNPLLIIP
HHEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHCCCHHHHHHHHHHH
FVLAPIFSLTTAYFATAAGWINHVVVQTPWTTPPIISGFLATGGDWRASVLQVIIIVVTV
HHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
FIYLPFLRMDEKVAFATAQKTEAK
HHHHHHHHCCCHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]