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The map label for this gene is inlI [H]

Identifier: 226222957

GI number: 226222957

Start: 357309

End: 360020

Strand: Direct

Name: inlI [H]

Synonym: Lm4b_00349

Alternate gene names: 226222957

Gene position: 357309-360020 (Clockwise)

Preceding gene: 226222955

Following gene: 226222958

Centisome position: 12.27

GC content: 38.27

Gene sequence:

>2712_bases
ATGAAAAGCAAAACAAAACAGATTATCATGATTGGAGTGGTCCTTTTTCAATCACTCTTCGCATACCCGTTAATCACCAT
GGCGGAAGAAAATGAATCGAAATCAGTAAATACAGAAACCACGTTAGAGCCTAAAGTAGCTCTCGAAGAAAAAACGCCTC
AGAAACCTACCCTTACCAATAATCTGAAGCAAGAAAAAACTGTCCTTCAAGCAGGCGAAACATATGAAACTGTTTTTCCT
GATGCAGCTTTAGCTACTGTAATTGCAAAAGCAGCAACTGGTTCAGAGGATATCACGCAAGAAGTATCGCAAACAGACTT
GAATAAAATCACTTCACTAACTGCTACATCTAAAGGGATAGTTGATTTAACAGGAATAGATTTACTTTCAAAATTAACCT
CTTTAAGTATAAGCGGGAACCAAATCACTGATATTTCTGCACTCAATGGTCTCGTGAATTTGTCCAATCTAAATGTATCT
AATAATAAAATAACAAGTTTCAACCTAAACGCGAATAGTAATTTACCTATGTTAAGCGCTGTTGATATTCGTAGTAATAA
CTTAAAAAATATAAATGTTCAAGACCAACCTAAATTACGCACCATTGAGTGTGACACAGGTAGTAGTTCAGAGTTGACAG
AAGTTACGCTAAAAAATCTTCCAATTTTGATAGTTGCAGGTAATGGCTCTAGTGCTTATCAAAATGATATTGTTTTTTCG
AGTACACCAGGATTAAGTAAGGTGATTCTAGAAAATTTACCATCAATAAGCTCTTCAGTACGATTAGATCGTTGCGCGAT
AGAAGAGTTAGTAATTAATAACCTTCCAAAAGTATCAATGGTAAATATAAGTAACAACAAAATTACTACACTAGAAGGAC
TTGAAAATTTATCTGCAGTAAACACTTTATACGTATCTGAGAATTTAGTGACTGAAATAGAGAACCTACATGCGTTCCCT
AAATTACAGACACTCACCGTAGACAATAACCATATCAGTGTATTGCCAACAAGTTTGAAAACGGAAAATCCCGTATTAAC
AACGCTAAGTGCGATGAATCAAACAATCACTCTAAAGCAAAAAGTTATCGTGTCAGACCTAGTTCTTGATAATGAAGTGA
AGAATTTCGGTCAAATAACCACTGCCAAATCCATCTCTAATAAGGGAACCTATCAAAATAACCAAATCAAGTGGCTTTTT
GAAGATATAAAAAGCGTGAATGCCGTTGATTATCAATTTAGTGAACCTGTTCAAGAGGCAACTATTCAAGGAACTTTTTC
GGGGAAAGTGACACAACCAATCAAAGCATCTAAAGTACCAGTTATTAGCGCAGATGCAGAGATGAATTACCCGAAAAACG
AAACGGTATCAGAAGCTGCCTTTTTCAAAGATATTTCTGCAAGCGTAACGGATGATGCAACACTAACTTCTGATTTTGAA
AGTGTTGTGGACTTTGCAAAAGCGGGAACGTATGAAGTGACATTAAATGCAGTGAATGAGGATGGAGTAAAAGCGACTTC
GGTGACTGTATTAGTGCATATCGCTAAGTCGCCAGCGCCAGTAATTACCGCAGATAAAGAAATCACATACACTAAAAACG
CGGAAGTCAGCATCACGGAATATCTTGCAGCGATTCATGCTAAAACGAATGATGGTTCACCAATTGAAAGTGATTTCGCT
ACGGCTGTAAATTGGGGCACTGCAGGAGATTATACCGTAACGCTAAGGTCTACAAATGAAGATGGAGTTGAAGCAATCCC
TGTAGAAGTAACTGTGCACATCGCCAAGTCGCCAGCGCCAGTAATTACCGCAGATAAAGAAATTACGTACGCTAAAAACG
CGGAAGTCAGCATCACGGAATATCTTGCAGCGATTCATGCTAAAACGAGTGATGGTTCATCAATTGAAGCTGATTTAGAT
ACGGCTGTAACATGGGGCACTGTAGGAGGTTATACCGTAACGCTAAGGTCTACAAATGAAGACGGAGTAGAAGCAATCCC
TGTAGAAGTAACTGTGCACATCGCTAAGTCACCAGCACCAGTAATTACCGCAGATAAAGAAATCACGTACGCTAAAAACG
CGGAAGTCAGCATAACGGAATTTCTTGCAGCGATTCATGCTAAAACGAGTGATGGTTCACCAATTGAAAGTGATTTCGCT
ACGGCTGTAATATGGAGCACTGCAGGAGATTATACCGTAACGTTAAAATCTACAAATGAAGATGGAGTAGAAGCAATCCC
TGTAGAAGTAAAGGTGCATATCGTAGAGCCACTAGCACCAACGATTTCGAATGTGACATTTGATGTGGATGATGTACAAA
CGACAGAATCTCTTGAAGCTGGAGAGCTAATTTCTGAACCATTGAGCCCAACAAAAGAAGGCTATACTTTTATTGGTTGG
TATGACTCGAAAACTGGTGGTAATAAATGGGATTTTACAACAGATAAAATGCCAGCATATAATATTATTCTTTATGCTCA
GTTTAGTAAAGATACAAATAAAGCAGAAGCGGCCGGTGGAGATAAGCCCTCAACACCCTCTTCTATAAAAGTAAGTCCAA
CAGGTCAGTCCGAGAGTGGAAACTTGGAAAATAGATCTAATATTAAATTACCAGCTACAGGCGATGATAATGCAACTGTT
TTATTAGTGGGCTTTGGATTACTAATGTTGGGGCTTTTCATTCGCCTTACTCAAAAAAAGCGTGCTAAATAA

Upstream 100 bases:

>100_bases
ACTTAAATAATACTTTTCAATGAAATAGTAGGTATTTTTAACTTGCTCATTCATTCTATTATTACTGAAGATGCTAACAA
CAACGAGAAGGAGATAGATT

Downstream 100 bases:

>100_bases
AAGCTCATAGAAATTTAAAAAATAGTGTAATTGGTTGCTTCTAGGAGATAAATAGTTGCAACTCACAAGGAGAGGAGACA
GAGAGCTGTCTCCTCTTTTT

Product: internalin, peptidoglycan bound protein (LPXTG motif)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 903; Mature: 903

Protein sequence:

>903_residues
MKSKTKQIIMIGVVLFQSLFAYPLITMAEENESKSVNTETTLEPKVALEEKTPQKPTLTNNLKQEKTVLQAGETYETVFP
DAALATVIAKAATGSEDITQEVSQTDLNKITSLTATSKGIVDLTGIDLLSKLTSLSISGNQITDISALNGLVNLSNLNVS
NNKITSFNLNANSNLPMLSAVDIRSNNLKNINVQDQPKLRTIECDTGSSSELTEVTLKNLPILIVAGNGSSAYQNDIVFS
STPGLSKVILENLPSISSSVRLDRCAIEELVINNLPKVSMVNISNNKITTLEGLENLSAVNTLYVSENLVTEIENLHAFP
KLQTLTVDNNHISVLPTSLKTENPVLTTLSAMNQTITLKQKVIVSDLVLDNEVKNFGQITTAKSISNKGTYQNNQIKWLF
EDIKSVNAVDYQFSEPVQEATIQGTFSGKVTQPIKASKVPVISADAEMNYPKNETVSEAAFFKDISASVTDDATLTSDFE
SVVDFAKAGTYEVTLNAVNEDGVKATSVTVLVHIAKSPAPVITADKEITYTKNAEVSITEYLAAIHAKTNDGSPIESDFA
TAVNWGTAGDYTVTLRSTNEDGVEAIPVEVTVHIAKSPAPVITADKEITYAKNAEVSITEYLAAIHAKTSDGSSIEADLD
TAVTWGTVGGYTVTLRSTNEDGVEAIPVEVTVHIAKSPAPVITADKEITYAKNAEVSITEFLAAIHAKTSDGSPIESDFA
TAVIWSTAGDYTVTLKSTNEDGVEAIPVEVKVHIVEPLAPTISNVTFDVDDVQTTESLEAGELISEPLSPTKEGYTFIGW
YDSKTGGNKWDFTTDKMPAYNIILYAQFSKDTNKAEAAGGDKPSTPSSIKVSPTGQSESGNLENRSNIKLPATGDDNATV
LLVGFGLLMLGLFIRLTQKKRAK

Sequences:

>Translated_903_residues
MKSKTKQIIMIGVVLFQSLFAYPLITMAEENESKSVNTETTLEPKVALEEKTPQKPTLTNNLKQEKTVLQAGETYETVFP
DAALATVIAKAATGSEDITQEVSQTDLNKITSLTATSKGIVDLTGIDLLSKLTSLSISGNQITDISALNGLVNLSNLNVS
NNKITSFNLNANSNLPMLSAVDIRSNNLKNINVQDQPKLRTIECDTGSSSELTEVTLKNLPILIVAGNGSSAYQNDIVFS
STPGLSKVILENLPSISSSVRLDRCAIEELVINNLPKVSMVNISNNKITTLEGLENLSAVNTLYVSENLVTEIENLHAFP
KLQTLTVDNNHISVLPTSLKTENPVLTTLSAMNQTITLKQKVIVSDLVLDNEVKNFGQITTAKSISNKGTYQNNQIKWLF
EDIKSVNAVDYQFSEPVQEATIQGTFSGKVTQPIKASKVPVISADAEMNYPKNETVSEAAFFKDISASVTDDATLTSDFE
SVVDFAKAGTYEVTLNAVNEDGVKATSVTVLVHIAKSPAPVITADKEITYTKNAEVSITEYLAAIHAKTNDGSPIESDFA
TAVNWGTAGDYTVTLRSTNEDGVEAIPVEVTVHIAKSPAPVITADKEITYAKNAEVSITEYLAAIHAKTSDGSSIEADLD
TAVTWGTVGGYTVTLRSTNEDGVEAIPVEVTVHIAKSPAPVITADKEITYAKNAEVSITEFLAAIHAKTSDGSPIESDFA
TAVIWSTAGDYTVTLKSTNEDGVEAIPVEVKVHIVEPLAPTISNVTFDVDDVQTTESLEAGELISEPLSPTKEGYTFIGW
YDSKTGGNKWDFTTDKMPAYNIILYAQFSKDTNKAEAAGGDKPSTPSSIKVSPTGQSESGNLENRSNIKLPATGDDNATV
LLVGFGLLMLGLFIRLTQKKRAK
>Mature_903_residues
MKSKTKQIIMIGVVLFQSLFAYPLITMAEENESKSVNTETTLEPKVALEEKTPQKPTLTNNLKQEKTVLQAGETYETVFP
DAALATVIAKAATGSEDITQEVSQTDLNKITSLTATSKGIVDLTGIDLLSKLTSLSISGNQITDISALNGLVNLSNLNVS
NNKITSFNLNANSNLPMLSAVDIRSNNLKNINVQDQPKLRTIECDTGSSSELTEVTLKNLPILIVAGNGSSAYQNDIVFS
STPGLSKVILENLPSISSSVRLDRCAIEELVINNLPKVSMVNISNNKITTLEGLENLSAVNTLYVSENLVTEIENLHAFP
KLQTLTVDNNHISVLPTSLKTENPVLTTLSAMNQTITLKQKVIVSDLVLDNEVKNFGQITTAKSISNKGTYQNNQIKWLF
EDIKSVNAVDYQFSEPVQEATIQGTFSGKVTQPIKASKVPVISADAEMNYPKNETVSEAAFFKDISASVTDDATLTSDFE
SVVDFAKAGTYEVTLNAVNEDGVKATSVTVLVHIAKSPAPVITADKEITYTKNAEVSITEYLAAIHAKTNDGSPIESDFA
TAVNWGTAGDYTVTLRSTNEDGVEAIPVEVTVHIAKSPAPVITADKEITYAKNAEVSITEYLAAIHAKTSDGSSIEADLD
TAVTWGTVGGYTVTLRSTNEDGVEAIPVEVTVHIAKSPAPVITADKEITYAKNAEVSITEFLAAIHAKTSDGSPIESDFA
TAVIWSTAGDYTVTLKSTNEDGVEAIPVEVKVHIVEPLAPTISNVTFDVDDVQTTESLEAGELISEPLSPTKEGYTFIGW
YDSKTGGNKWDFTTDKMPAYNIILYAQFSKDTNKAEAAGGDKPSTPSSIKVSPTGQSESGNLENRSNIKLPATGDDNATV
LLVGFGLLMLGLFIRLTQKKRAK

Specific function: Unknown. A role in virulence could not be demonstrated [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 MucBP domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR000601
- InterPro:   IPR001899 [H]

Pfam domain/function: PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 96876; Mature: 96876

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKTKQIIMIGVVLFQSLFAYPLITMAEENESKSVNTETTLEPKVALEEKTPQKPTLTN
CCCCHHEEEEHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHC
NLKQEKTVLQAGETYETVFPDAALATVIAKAATGSEDITQEVSQTDLNKITSLTATSKGI
CHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
VDLTGIDLLSKLTSLSISGNQITDISALNGLVNLSNLNVSNNKITSFNLNANSNLPMLSA
EEEHHHHHHHHHHHEECCCCCEEEHHHHCCEEEEEEECCCCCEEEEEEECCCCCCCEEEE
VDIRSNNLKNINVQDQPKLRTIECDTGSSSELTEVTLKNLPILIVAGNGSSAYQNDIVFS
EEECCCCCEECCCCCCCCEEEEEECCCCCCCHHHEECCCCCEEEEECCCCCCCCCCEEEE
STPGLSKVILENLPSISSSVRLDRCAIEELVINNLPKVSMVNISNNKITTLEGLENLSAV
CCCCHHHHHHHCCCCCHHHCCHHHHHHHHHHHCCCCCEEEEEECCCEEEEHHHHHHHHHH
NTLYVSENLVTEIENLHAFPKLQTLTVDNNHISVLPTSLKTENPVLTTLSAMNQTITLKQ
EEEEECHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHCCCEEEEHH
KVIVSDLVLDNEVKNFGQITTAKSISNKGTYQNNQIKWLFEDIKSVNAVDYQFSEPVQEA
HHHHHHHHHHHHHHHHCCEEEHHHCCCCCCCCCCCEEHHHHHHHCCCEECEECCCCHHHH
TIQGTFSGKVTQPIKASKVPVISADAEMNYPKNETVSEAAFFKDISASVTDDATLTSDFE
EEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHH
SVVDFAKAGTYEVTLNAVNEDGVKATSVTVLVHIAKSPAPVITADKEITYTKNAEVSITE
HHHHHHHCCCEEEEEEECCCCCCEEEEEEEEEEEECCCCCEEECCCEEEEECCCCEEHHH
YLAAIHAKTNDGSPIESDFATAVNWGTAGDYTVTLRSTNEDGVEAIPVEVTVHIAKSPAP
HHHHHEECCCCCCCCCCCHHHEEECCCCCCEEEEEECCCCCCCEEEEEEEEEEEECCCCC
VITADKEITYAKNAEVSITEYLAAIHAKTSDGSSIEADLDTAVTWGTVGGYTVTLRSTNE
EEECCCCEEEECCCCEEHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCEEEEEECCCC
DGVEAIPVEVTVHIAKSPAPVITADKEITYAKNAEVSITEFLAAIHAKTSDGSPIESDFA
CCCEEEEEEEEEEEECCCCCEEECCCCEEEECCCCEEHHHHHHHHHCCCCCCCCCCCCCE
TAVIWSTAGDYTVTLKSTNEDGVEAIPVEVKVHIVEPLAPTISNVTFDVDDVQTTESLEA
EEEEEECCCCEEEEEECCCCCCCEEEEEEEEEEEECCCCCCCCCCEEECCCCCCCCCCCH
GELISEPLSPTKEGYTFIGWYDSKTGGNKWDFTTDKMPAYNIILYAQFSKDTNKAEAAGG
HHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHCCCC
DKPSTPSSIKVSPTGQSESGNLENRSNIKLPATGDDNATVLLVGFGLLMLGLFIRLTQKK
CCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
RAK
CCC
>Mature Secondary Structure
MKSKTKQIIMIGVVLFQSLFAYPLITMAEENESKSVNTETTLEPKVALEEKTPQKPTLTN
CCCCHHEEEEHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHC
NLKQEKTVLQAGETYETVFPDAALATVIAKAATGSEDITQEVSQTDLNKITSLTATSKGI
CHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
VDLTGIDLLSKLTSLSISGNQITDISALNGLVNLSNLNVSNNKITSFNLNANSNLPMLSA
EEEHHHHHHHHHHHEECCCCCEEEHHHHCCEEEEEEECCCCCEEEEEEECCCCCCCEEEE
VDIRSNNLKNINVQDQPKLRTIECDTGSSSELTEVTLKNLPILIVAGNGSSAYQNDIVFS
EEECCCCCEECCCCCCCCEEEEEECCCCCCCHHHEECCCCCEEEEECCCCCCCCCCEEEE
STPGLSKVILENLPSISSSVRLDRCAIEELVINNLPKVSMVNISNNKITTLEGLENLSAV
CCCCHHHHHHHCCCCCHHHCCHHHHHHHHHHHCCCCCEEEEEECCCEEEEHHHHHHHHHH
NTLYVSENLVTEIENLHAFPKLQTLTVDNNHISVLPTSLKTENPVLTTLSAMNQTITLKQ
EEEEECHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHCCCEEEEHH
KVIVSDLVLDNEVKNFGQITTAKSISNKGTYQNNQIKWLFEDIKSVNAVDYQFSEPVQEA
HHHHHHHHHHHHHHHHCCEEEHHHCCCCCCCCCCCEEHHHHHHHCCCEECEECCCCHHHH
TIQGTFSGKVTQPIKASKVPVISADAEMNYPKNETVSEAAFFKDISASVTDDATLTSDFE
EEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHH
SVVDFAKAGTYEVTLNAVNEDGVKATSVTVLVHIAKSPAPVITADKEITYTKNAEVSITE
HHHHHHHCCCEEEEEEECCCCCCEEEEEEEEEEEECCCCCEEECCCEEEEECCCCEEHHH
YLAAIHAKTNDGSPIESDFATAVNWGTAGDYTVTLRSTNEDGVEAIPVEVTVHIAKSPAP
HHHHHEECCCCCCCCCCCHHHEEECCCCCCEEEEEECCCCCCCEEEEEEEEEEEECCCCC
VITADKEITYAKNAEVSITEYLAAIHAKTSDGSSIEADLDTAVTWGTVGGYTVTLRSTNE
EEECCCCEEEECCCCEEHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCEEEEEECCCC
DGVEAIPVEVTVHIAKSPAPVITADKEITYAKNAEVSITEFLAAIHAKTSDGSPIESDFA
CCCEEEEEEEEEEEECCCCCEEECCCCEEEECCCCEEHHHHHHHHHCCCCCCCCCCCCCE
TAVIWSTAGDYTVTLKSTNEDGVEAIPVEVKVHIVEPLAPTISNVTFDVDDVQTTESLEA
EEEEEECCCCEEEEEECCCCCCCEEEEEEEEEEEECCCCCCCCCCEEECCCCCCCCCCCH
GELISEPLSPTKEGYTFIGWYDSKTGGNKWDFTTDKMPAYNIILYAQFSKDTNKAEAAGG
HHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHCCCC
DKPSTPSSIKVSPTGQSESGNLENRSNIKLPATGDDNATVLLVGFGLLMLGLFIRLTQKK
CCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
RAK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]