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The map label for this gene is esxA [H]

Identifier: 226222701

GI number: 226222701

Start: 66670

End: 66963

Strand: Direct

Name: esxA [H]

Synonym: Lm4b_00065

Alternate gene names: 226222701

Gene position: 66670-66963 (Clockwise)

Preceding gene: 226222700

Following gene: 226222702

Centisome position: 2.29

GC content: 38.44

Gene sequence:

>294_bases
ATGTCAGGTCAAATTCGTATGAGTCCAAGCGAACTACGTGATCGCGCGAAAACTTACGGTCAAAGTGGTCGGGATATTGA
GGATATTCTAAGTCGTTTAAGTCAACTACAAGAACAACTACGTAGCGAATGGGAAGGTCAAGCTTTTATGCGTTTTGATG
ATCAATTTGAACAATTAAAACCAAAAGTAACTGAATTCGCAAACTTAATGGATCAAATTAACGATCAACTTGAGAAGACA
GCAAACGCAGTAGAAGAGCACGATCAACAACTTTCTCAAAACTTCGGATTCTAA

Upstream 100 bases:

>100_bases
AGTTTTATTCGTATTTTTGTCACATTTTACTTTGTGAATTCATGTTATAATTTGAGAGTGATATCTTATTCACAATAGAT
AATAAGAGGAGATGAAGTGA

Downstream 100 bases:

>100_bases
AATCAACAAAAAGTGGGGCATACATACAAATATCGTTGGATGCTTTACGAAAAGCCATGCAGTTTTTTGCATGGCTTTTT
CTAAACATAGAAAGCTTATG

Product: heat shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MSGQIRMSPSELRDRAKTYGQSGRDIEDILSRLSQLQEQLRSEWEGQAFMRFDDQFEQLKPKVTEFANLMDQINDQLEKT
ANAVEEHDQQLSQNFGF

Sequences:

>Translated_97_residues
MSGQIRMSPSELRDRAKTYGQSGRDIEDILSRLSQLQEQLRSEWEGQAFMRFDDQFEQLKPKVTEFANLMDQINDQLEKT
ANAVEEHDQQLSQNFGF
>Mature_96_residues
SGQIRMSPSELRDRAKTYGQSGRDIEDILSRLSQLQEQLRSEWEGQAFMRFDDQFEQLKPKVTEFANLMDQINDQLEKTA
NAVEEHDQQLSQNFGF

Specific function: Virulence factor that is important for the establishment of infection in the host [H]

COG id: COG4842

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ESAT-6 (esx) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010310 [H]

Pfam domain/function: PF06013 WXG100 [H]

EC number: NA

Molecular weight: Translated: 11357; Mature: 11225

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQIRMSPSELRDRAKTYGQSGRDIEDILSRLSQLQEQLRSEWEGQAFMRFDDQFEQLK
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
PKVTEFANLMDQINDQLEKTANAVEEHDQQLSQNFGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGQIRMSPSELRDRAKTYGQSGRDIEDILSRLSQLQEQLRSEWEGQAFMRFDDQFEQLK
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
PKVTEFANLMDQINDQLEKTANAVEEHDQQLSQNFGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA