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The map label for this gene is licC [H]

Identifier: 226222679

GI number: 226222679

Start: 44211

End: 45569

Strand: Direct

Name: licC [H]

Synonym: Lm4b_00043

Alternate gene names: 226222679

Gene position: 44211-45569 (Clockwise)

Preceding gene: 226222678

Following gene: 226222680

Centisome position: 1.52

GC content: 39.81

Gene sequence:

>1359_bases
ATGAGTTCAGAGAGAAGTTTATCTAGCCGATTTATTGAAGGATTATCAATTTTTGCCCAAAAAATTTCATCGCAAAAGCA
TATCATGGCAATTCGTGATGGCTTTGCAGCGATGATTCCGATTACGATTATTGCCGCATTTTTCTTGCTTGTAAATAACG
TGTTACTTCAACCAGAAAATGGTCTGCTTAAATTCATTCCAAATGTAGAAAATTATTTGGGTGTAGGTATTCAAGTCTAT
AACGCGACACTCGGTATTATGGCGATTTTAGCAGCATTCTTAATTGGTAACTTTTTAGCTAAATCATACGGAATGGAAGG
GCGTACGGAAGGGGTTATCGCTGTAGCTGCTTATGTTGTTTTAATACCGGCATCTTCACATTTAATGTCGGTTGACGGTA
AAGCTTTTGAGGCTGGCGGCGTTTTAACCCAAGAAATGACAAGTTCGACAGGAATGTTCCTTGCAATCATCGCTGCTTTA
GTCAGTGTTACCATGCTTGCGAAATTCTCGAAAAGTAAAAAATTAAAAATCTCTATGCCTGAAAGTGTTCCACCGGCAAT
TGCAAAATCATTTAACATTTTAATTCCATCATTCTTAGTTCTAAGTATTTTAGCAATTATTGAAGTGCTTGTAGTTAGTT
TTGTATCAATGAGTATTCCAGAAATTATCGTAAAAGTACTACAAATTCCATTAGTTGGCGGGTTCCAAACGTTACCAGGT
ATTCTACTTTATGTATTTTTAGCGGGATTCTTATGGGTCTTTGGTATTCACGGCGCATTCGTATTAGGCGCGATTTCTGG
ACCAGTTCTTTTAACTTCTTTACAACAAAATATTGATGCAGTGAATGCAGGGACAGCTTTACCGAACATCGTTACACAAC
CGTTTTTAGATGCTTTTGTATACATGGGTGGCGGCGGAACCATCATCTGTTTAGTTATCGCGATTTTCATTGCTTCTAAA
CGACCGGATCACCGCATGGTCACAAAATTCGGCTTAATTCCGAGTATTTTCAACGTCAGCGAACCACTAATGTTCGGACT
GCCAGTTGTATTCAACCCGATTTATGGTATTCCATTAGTTATTGCACCTCTAGCTTCGACTGCAATGGCATACTTCGCAA
CTTCATGGGGCTGGATTAGCCAAACTTATATTTTGATTCCGTGGGTGACGCCACCAGTGCTTTCGGGTTACCTTGCGACA
GGCGGAGACATTCGCGCGTCCATCCTTCAAATCGCAATTATTATCGTTGGAACGCTGATTTACCTACCATTTGTACTCGT
AGCAAACCGCGCGTATGTTTTAGAACAAAAAGCTGCTGGGAAAGTAGAAGCAGAAACAGTAACGAATGGAGAAGTTTAA

Upstream 100 bases:

>100_bases
TGCAACTTATAAGGAAGTTTGGGTCGGTAATGCCGGCAAATGGATGTCAATTGTAGCAGATTTAAACAAAATAACAGGAA
AGTCATAGGAGGACAAAAAA

Downstream 100 bases:

>100_bases
AATGAAACCAACAATGATGACGTATATTAATGAAGAAGAGGAAATGTGTCGAGTAATTTTAGCAGATTTCCAAACAAATG
CAGAAAAACTAGAATCACTC

Product: PTS system, cellobiose-specific IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSSERSLSSRFIEGLSIFAQKISSQKHIMAIRDGFAAMIPITIIAAFFLLVNNVLLQPENGLLKFIPNVENYLGVGIQVY
NATLGIMAILAAFLIGNFLAKSYGMEGRTEGVIAVAAYVVLIPASSHLMSVDGKAFEAGGVLTQEMTSSTGMFLAIIAAL
VSVTMLAKFSKSKKLKISMPESVPPAIAKSFNILIPSFLVLSILAIIEVLVVSFVSMSIPEIIVKVLQIPLVGGFQTLPG
ILLYVFLAGFLWVFGIHGAFVLGAISGPVLLTSLQQNIDAVNAGTALPNIVTQPFLDAFVYMGGGGTIICLVIAIFIASK
RPDHRMVTKFGLIPSIFNVSEPLMFGLPVVFNPIYGIPLVIAPLASTAMAYFATSWGWISQTYILIPWVTPPVLSGYLAT
GGDIRASILQIAIIIVGTLIYLPFVLVANRAYVLEQKAAGKVEAETVTNGEV

Sequences:

>Translated_452_residues
MSSERSLSSRFIEGLSIFAQKISSQKHIMAIRDGFAAMIPITIIAAFFLLVNNVLLQPENGLLKFIPNVENYLGVGIQVY
NATLGIMAILAAFLIGNFLAKSYGMEGRTEGVIAVAAYVVLIPASSHLMSVDGKAFEAGGVLTQEMTSSTGMFLAIIAAL
VSVTMLAKFSKSKKLKISMPESVPPAIAKSFNILIPSFLVLSILAIIEVLVVSFVSMSIPEIIVKVLQIPLVGGFQTLPG
ILLYVFLAGFLWVFGIHGAFVLGAISGPVLLTSLQQNIDAVNAGTALPNIVTQPFLDAFVYMGGGGTIICLVIAIFIASK
RPDHRMVTKFGLIPSIFNVSEPLMFGLPVVFNPIYGIPLVIAPLASTAMAYFATSWGWISQTYILIPWVTPPVLSGYLAT
GGDIRASILQIAIIIVGTLIYLPFVLVANRAYVLEQKAAGKVEAETVTNGEV
>Mature_451_residues
SSERSLSSRFIEGLSIFAQKISSQKHIMAIRDGFAAMIPITIIAAFFLLVNNVLLQPENGLLKFIPNVENYLGVGIQVYN
ATLGIMAILAAFLIGNFLAKSYGMEGRTEGVIAVAAYVVLIPASSHLMSVDGKAFEAGGVLTQEMTSSTGMFLAIIAALV
SVTMLAKFSKSKKLKISMPESVPPAIAKSFNILIPSFLVLSILAIIEVLVVSFVSMSIPEIIVKVLQIPLVGGFQTLPGI
LLYVFLAGFLWVFGIHGAFVLGAISGPVLLTSLQQNIDAVNAGTALPNIVTQPFLDAFVYMGGGGTIICLVIAIFIASKR
PDHRMVTKFGLIPSIFNVSEPLMFGLPVVFNPIYGIPLVIAPLASTAMAYFATSWGWISQTYILIPWVTPPVLSGYLATG
GDIRASILQIAIIIVGTLIYLPFVLVANRAYVLEQKAAGKVEAETVTNGEV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=447, Percent_Identity=33.5570469798658, Blast_Score=221, Evalue=6e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 48232; Mature: 48101

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSERSLSSRFIEGLSIFAQKISSQKHIMAIRDGFAAMIPITIIAAFFLLVNNVLLQPEN
CCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GLLKFIPNVENYLGVGIQVYNATLGIMAILAAFLIGNFLAKSYGMEGRTEGVIAVAAYVV
CCEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LIPASSHLMSVDGKAFEAGGVLTQEMTSSTGMFLAIIAALVSVTMLAKFSKSKKLKISMP
HCCCCCCEEECCCCEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECC
ESVPPAIAKSFNILIPSFLVLSILAIIEVLVVSFVSMSIPEIIVKVLQIPLVGGFQTLPG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ILLYVFLAGFLWVFGIHGAFVLGAISGPVLLTSLQQNIDAVNAGTALPNIVTQPFLDAFV
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHH
YMGGGGTIICLVIAIFIASKRPDHRMVTKFGLIPSIFNVSEPLMFGLPVVFNPIYGIPLV
HCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHCCCCHHHHCCHHHHCCCCCHHHH
IAPLASTAMAYFATSWGWISQTYILIPWVTPPVLSGYLATGGDIRASILQIAIIIVGTLI
HHHHHHHHHHHHHHCCCHHCCCEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
YLPFVLVANRAYVLEQKAAGKVEAETVTNGEV
HHHHHHHHCCHHEEHHHCCCCEEECCCCCCCC
>Mature Secondary Structure 
SSERSLSSRFIEGLSIFAQKISSQKHIMAIRDGFAAMIPITIIAAFFLLVNNVLLQPEN
CCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GLLKFIPNVENYLGVGIQVYNATLGIMAILAAFLIGNFLAKSYGMEGRTEGVIAVAAYVV
CCEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LIPASSHLMSVDGKAFEAGGVLTQEMTSSTGMFLAIIAALVSVTMLAKFSKSKKLKISMP
HCCCCCCEEECCCCEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECC
ESVPPAIAKSFNILIPSFLVLSILAIIEVLVVSFVSMSIPEIIVKVLQIPLVGGFQTLPG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ILLYVFLAGFLWVFGIHGAFVLGAISGPVLLTSLQQNIDAVNAGTALPNIVTQPFLDAFV
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHH
YMGGGGTIICLVIAIFIASKRPDHRMVTKFGLIPSIFNVSEPLMFGLPVVFNPIYGIPLV
HCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHCCCCHHHHCCHHHHCCCCCHHHH
IAPLASTAMAYFATSWGWISQTYILIPWVTPPVLSGYLATGGDIRASILQIAIIIVGTLI
HHHHHHHHHHHHHHCCCHHCCCEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
YLPFVLVANRAYVLEQKAAGKVEAETVTNGEV
HHHHHHHHCCHHEEHHHCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]