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The map label for this gene is qoxB

Identifier: 226222654

GI number: 226222654

Start: 19425

End: 21404

Strand: Direct

Name: qoxB

Synonym: Lm4b_00017

Alternate gene names: 226222654

Gene position: 19425-21404 (Clockwise)

Preceding gene: 226222653

Following gene: 226222655

Centisome position: 0.67

GC content: 40.61

Gene sequence:

>1980_bases
ATGAAATGGAATGAGTTTATCGTAACTGGCGACCCAATGATTTTAGGCGCGCAGATTTCTATCGTACTTGTAAGTATTGG
TGTTGTTGCGTTACTAACTTATACAAAAAAATGGAAGTGGCTCATGAAAGAGTGGATTTCTTCCGTTGATCATAAAAAAA
TTGGTATTATGTACTTGCTTGCTGCTGTCTTAATGTTTTTCCGTGGTGGTGTGGATGCGCTAATGATGCGTACCCAGCTC
GCTTTACCGGATATGAAATTTTTAGACGCACAGCATTACAATGAAGTTTTTTCTACACATGGAACGATTATGATTTTATT
TATGGCGATGCCGTTTATCATCGGATTGATGAACATTGCCGTACCACTTCAAATTGGTGCGCGTGATGTAGCATTTCCAT
TTTTAAACAACTTAAGTTTTTGGACGTTCTTTATGGGAGCGATGCTATTTAACTTATCATTCGTAATTGGTGGTTCGCCA
GATGCTGGTTGGACAAACTATGCGCCACTTGCGACAGATTTTAGCGCTGGATATGGAATTAACTTCTATCTTCTAGGTGT
TCAAATCGCTGGTATTGGTACGCTGATGACGGGGATTAACTTTTTCGTCACGATTTTAAGAATGCGTACAAAAGGTATGA
CGTTAATGAAAATGCCAATGTTTACTTGGTCTTCATTAATTACAAGTTTGATCATTATTTTCGCTTTCCCAGTTTTAACA
GTGGCACTTGCTTTGATGTCATTTGACCGACTGTTTGGGACAGCATTCTTCACACTCACGAATGGCGGGCTCCCAATGAT
GTGGGCCAACTTGTTCTGGGTTTGGGGTCATCCGGAAGTATATATTGTTATTTTGCCAGCTTTCGGTATTTTCTCAGAGA
TTATTTCTACTTTCTCGAGGAAAAAATTATTCGGTTATCCGGCGATGGTTGCCGCGATGGCAGTTATTTCTTTACTAAGT
TTCCTAGTTTGGGTCCATCACTTCTTTACAATGGGATCAGGGGCGCTTGTTAACTCCTTCTTCTCCATTACAACGATGAT
GATTGCGATACCGACCGGGATTAAGATATTCAACTGGCTCTTTACGATGTACAAAGGGCGAATAACCTTTACAACGCCAA
TGCTTTGGTCGCTTGCCTTTATCCCTAACTTTGTTGTTGGTGGGGTAACTGGGGTTATGCTTGCGATGGCTGCAGCCGAT
TATCAATATCACAATACGTACTTCTTAGTATCCCATTTCCACTACGTATTAATTGCTGGAACTGTGTTCTCCTGCTTTGC
CGGGCTTACATACTGGTATCCAAAAATGGTCGGTTACAGACTAAATGAAAAAATTGGTAAATGGTTCTTCTGGATTTTCG
TTGTTGGATTTAACGTTTGTTTCTTCCCGCAATATTTCCTAGGACTAGATGGTATGCCGCGTCGTATTTACACTTACGTA
CAAGGTGATGGCTGGACAACGCTTAACTTTATCTCTACTGTGGGCGGATTCTTGATGGGTGTAGCATTCTTAGTTCTTTG
CTACAACATCTACTACAGCTACAAAAACTCTAAACGTGAAGTTACTGGTGACCCGTGGGATGCTCGTACGCTTGAATGGG
CTACAAGTTCCGCTGTTCCTCCAAAATATAACTTTGCTGTTTTACCTGAATGGAATGACTTGGATGATTTCTGGAATAGA
AAACAAAAAGGCGATCCATATGTAAATGATAAAAATTATAAACCAATCCATATGCCAAGTAATACCATGGTTGGGTTTGT
AATGTCTGTCTTCTTCTTCATTGCAGGTTTCGGACTAGTCTTCTACTGGTACTGGATGGGAATTATTGGCCTAGTTGGTA
TTTTAGGATGTATGATTTATCGTTCATTCCAAAATAACGATGGTTACCACGTTGAAGTGGACGAAATTAAAGCAACAGAA
GAACATAATGCGCGCGAACTTGCGACTGGTGTGAAGGAGGGTAACCCATGGAATCTGTAG

Upstream 100 bases:

>100_bases
CGAAGATGAAATGAAGAAAATGGAAGAAGACATCCAAACAAATGAATTCAATAAAAAAGAATCGGATGACGCAGGGAAGT
AAAAAGGGGGGACATAAGGC

Downstream 100 bases:

>100_bases
AAACAAATAAAAATCTGCCAATTGAATATAGATCAGAACAAGGTCGATTAAATATTCTTGGATTCTGGATTTTCCTTGGC
GCCGAAATTGCATTGTTTGC

Product: AA3-600 quinol oxidase subunit I

Products: NA

Alternate protein names: Oxidase aa(3)-600 subunit 1; Quinol oxidase aa3-600, subunit qoxB; Quinol oxidase polypeptide I [H]

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MKWNEFIVTGDPMILGAQISIVLVSIGVVALLTYTKKWKWLMKEWISSVDHKKIGIMYLLAAVLMFFRGGVDALMMRTQL
ALPDMKFLDAQHYNEVFSTHGTIMILFMAMPFIIGLMNIAVPLQIGARDVAFPFLNNLSFWTFFMGAMLFNLSFVIGGSP
DAGWTNYAPLATDFSAGYGINFYLLGVQIAGIGTLMTGINFFVTILRMRTKGMTLMKMPMFTWSSLITSLIIIFAFPVLT
VALALMSFDRLFGTAFFTLTNGGLPMMWANLFWVWGHPEVYIVILPAFGIFSEIISTFSRKKLFGYPAMVAAMAVISLLS
FLVWVHHFFTMGSGALVNSFFSITTMMIAIPTGIKIFNWLFTMYKGRITFTTPMLWSLAFIPNFVVGGVTGVMLAMAAAD
YQYHNTYFLVSHFHYVLIAGTVFSCFAGLTYWYPKMVGYRLNEKIGKWFFWIFVVGFNVCFFPQYFLGLDGMPRRIYTYV
QGDGWTTLNFISTVGGFLMGVAFLVLCYNIYYSYKNSKREVTGDPWDARTLEWATSSAVPPKYNFAVLPEWNDLDDFWNR
KQKGDPYVNDKNYKPIHMPSNTMVGFVMSVFFFIAGFGLVFYWYWMGIIGLVGILGCMIYRSFQNNDGYHVEVDEIKATE
EHNARELATGVKEGNPWNL

Sequences:

>Translated_659_residues
MKWNEFIVTGDPMILGAQISIVLVSIGVVALLTYTKKWKWLMKEWISSVDHKKIGIMYLLAAVLMFFRGGVDALMMRTQL
ALPDMKFLDAQHYNEVFSTHGTIMILFMAMPFIIGLMNIAVPLQIGARDVAFPFLNNLSFWTFFMGAMLFNLSFVIGGSP
DAGWTNYAPLATDFSAGYGINFYLLGVQIAGIGTLMTGINFFVTILRMRTKGMTLMKMPMFTWSSLITSLIIIFAFPVLT
VALALMSFDRLFGTAFFTLTNGGLPMMWANLFWVWGHPEVYIVILPAFGIFSEIISTFSRKKLFGYPAMVAAMAVISLLS
FLVWVHHFFTMGSGALVNSFFSITTMMIAIPTGIKIFNWLFTMYKGRITFTTPMLWSLAFIPNFVVGGVTGVMLAMAAAD
YQYHNTYFLVSHFHYVLIAGTVFSCFAGLTYWYPKMVGYRLNEKIGKWFFWIFVVGFNVCFFPQYFLGLDGMPRRIYTYV
QGDGWTTLNFISTVGGFLMGVAFLVLCYNIYYSYKNSKREVTGDPWDARTLEWATSSAVPPKYNFAVLPEWNDLDDFWNR
KQKGDPYVNDKNYKPIHMPSNTMVGFVMSVFFFIAGFGLVFYWYWMGIIGLVGILGCMIYRSFQNNDGYHVEVDEIKATE
EHNARELATGVKEGNPWNL
>Mature_659_residues
MKWNEFIVTGDPMILGAQISIVLVSIGVVALLTYTKKWKWLMKEWISSVDHKKIGIMYLLAAVLMFFRGGVDALMMRTQL
ALPDMKFLDAQHYNEVFSTHGTIMILFMAMPFIIGLMNIAVPLQIGARDVAFPFLNNLSFWTFFMGAMLFNLSFVIGGSP
DAGWTNYAPLATDFSAGYGINFYLLGVQIAGIGTLMTGINFFVTILRMRTKGMTLMKMPMFTWSSLITSLIIIFAFPVLT
VALALMSFDRLFGTAFFTLTNGGLPMMWANLFWVWGHPEVYIVILPAFGIFSEIISTFSRKKLFGYPAMVAAMAVISLLS
FLVWVHHFFTMGSGALVNSFFSITTMMIAIPTGIKIFNWLFTMYKGRITFTTPMLWSLAFIPNFVVGGVTGVMLAMAAAD
YQYHNTYFLVSHFHYVLIAGTVFSCFAGLTYWYPKMVGYRLNEKIGKWFFWIFVVGFNVCFFPQYFLGLDGMPRRIYTYV
QGDGWTTLNFISTVGGFLMGVAFLVLCYNIYYSYKNSKREVTGDPWDARTLEWATSSAVPPKYNFAVLPEWNDLDDFWNR
KQKGDPYVNDKNYKPIHMPSNTMVGFVMSVFFFIAGFGLVFYWYWMGIIGLVGILGCMIYRSFQNNDGYHVEVDEIKATE
EHNARELATGVKEGNPWNL

Specific function: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=505, Percent_Identity=40, Blast_Score=358, Evalue=1e-98,
Organism=Escherichia coli, GI1786634, Length=652, Percent_Identity=51.3803680981595, Blast_Score=679, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=480, Percent_Identity=41.6666666666667, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=41.0493827160494, Blast_Score=254, Evalue=3e-68,
Organism=Saccharomyces cerevisiae, GI6226523, Length=248, Percent_Identity=33.0645161290323, Blast_Score=141, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.9.3.-

Molecular weight: Translated: 74901; Mature: 74901

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWNEFIVTGDPMILGAQISIVLVSIGVVALLTYTKKWKWLMKEWISSVDHKKIGIMYLL
CCCCCEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAVLMFFRGGVDALMMRTQLALPDMKFLDAQHYNEVFSTHGTIMILFMAMPFIIGLMNIA
HHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VPLQIGARDVAFPFLNNLSFWTFFMGAMLFNLSFVIGGSPDAGWTNYAPLATDFSAGYGI
HEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCC
NFYLLGVQIAGIGTLMTGINFFVTILRMRTKGMTLMKMPMFTWSSLITSLIIIFAFPVLT
EEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
VALALMSFDRLFGTAFFTLTNGGLPMMWANLFWVWGHPEVYIVILPAFGIFSEIISTFSR
HHHHHHHHHHHHHHHEEEEECCCCHHEECCEEEEECCCEEEEEEECHHHHHHHHHHHHHH
KKLFGYPAMVAAMAVISLLSFLVWVHHFFTMGSGALVNSFFSITTMMIAIPTGIKIFNWL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
FTMYKGRITFTTPMLWSLAFIPNFVVGGVTGVMLAMAAADYQYHNTYFLVSHFHYVLIAG
HHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCEEEEHHHHHHHHHHH
TVFSCFAGLTYWYPKMVGYRLNEKIGKWFFWIFVVGFNVCFFPQYFLGLDGMPRRIYTYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
QGDGWTTLNFISTVGGFLMGVAFLVLCYNIYYSYKNSKREVTGDPWDARTLEWATSSAVP
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCC
PKYNFAVLPEWNDLDDFWNRKQKGDPYVNDKNYKPIHMPSNTMVGFVMSVFFFIAGFGLV
CCCCEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHH
FYWYWMGIIGLVGILGCMIYRSFQNNDGYHVEVDEIKATEEHNARELATGVKEGNPWNL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHCCCCCCCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKWNEFIVTGDPMILGAQISIVLVSIGVVALLTYTKKWKWLMKEWISSVDHKKIGIMYLL
CCCCCEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAVLMFFRGGVDALMMRTQLALPDMKFLDAQHYNEVFSTHGTIMILFMAMPFIIGLMNIA
HHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VPLQIGARDVAFPFLNNLSFWTFFMGAMLFNLSFVIGGSPDAGWTNYAPLATDFSAGYGI
HEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCC
NFYLLGVQIAGIGTLMTGINFFVTILRMRTKGMTLMKMPMFTWSSLITSLIIIFAFPVLT
EEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
VALALMSFDRLFGTAFFTLTNGGLPMMWANLFWVWGHPEVYIVILPAFGIFSEIISTFSR
HHHHHHHHHHHHHHHEEEEECCCCHHEECCEEEEECCCEEEEEEECHHHHHHHHHHHHHH
KKLFGYPAMVAAMAVISLLSFLVWVHHFFTMGSGALVNSFFSITTMMIAIPTGIKIFNWL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
FTMYKGRITFTTPMLWSLAFIPNFVVGGVTGVMLAMAAADYQYHNTYFLVSHFHYVLIAG
HHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCEEEEHHHHHHHHHHH
TVFSCFAGLTYWYPKMVGYRLNEKIGKWFFWIFVVGFNVCFFPQYFLGLDGMPRRIYTYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
QGDGWTTLNFISTVGGFLMGVAFLVLCYNIYYSYKNSKREVTGDPWDARTLEWATSSAVP
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCC
PKYNFAVLPEWNDLDDFWNRKQKGDPYVNDKNYKPIHMPSNTMVGFVMSVFFFIAGFGLV
CCCCEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHH
FYWYWMGIIGLVGILGCMIYRSFQNNDGYHVEVDEIKATEEHNARELATGVKEGNPWNL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHCCCCCCCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7575098 [H]