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The map label for this gene is qoxA

Identifier: 226222653

GI number: 226222653

Start: 18300

End: 19406

Strand: Direct

Name: qoxA

Synonym: Lm4b_00016

Alternate gene names: 226222653

Gene position: 18300-19406 (Clockwise)

Preceding gene: 226222651

Following gene: 226222654

Centisome position: 0.63

GC content: 38.12

Gene sequence:

>1107_bases
GTGTCAAAGGTACTTAAATCTTTGCTGCTTACGGCACTACTTGGGGTTACCGGCCTTATAAGTGGTTGTGGTGACTTGAC
GGTACTTAATCCAAAAGGGCCAGTTGCAAAAGGTCAGTCGGACTTAATTATTTATTCGATTATATTTATGCTGGTTATTG
TTTTGACGATTTTTGTATTGTTTACGATTATGTTGGTTAAATACCGCGAACGGAAAGACATTTCAAACTATGAGCCGGAT
ATGCACGGTAGTAAAAAACTGGAAATTTTTTGGACATTGATTCCAGTTGCAATCGTTATTGCTCTAGCTATTCCGACTGT
AAAAACAATTTATGCAGGGGAAGAAGCACCAAAAGTGACTTCGCATAAAGATCCAATTGTTATTTACGCAACAAGTGCAG
ACTGGAAATGGATTTTTAGTTATCCAGATGAGTCAATTGAAACAGTCAACTATGTAAATATTCCAACCGACCGTCCTGTA
CTATTCAAATTAACTTCTGCAGATACGATGACAAGCTTTTGGGTTCCGCAATTAGGTGGACAAAAATATGCGATGTCTGG
CATGACGATGAATTTATATTTACAAGCAGATGAAGTTGGTACATATAAAGGCCGTAACGCAAACTTCAACGGCGAAGGTT
TTGCGGATCAACGCTTTGATGTAGTAGCTCAATCTGAAAAAGATTTCAAAAAATGGGCGAAAGAAACAAAAGCAAGCTCG
CCAGTTATTACACAAGACATATATGATCGTCTTTTAATTCCTGGAAGCTCTAAGAAAAAGACTTATTCTGGTACGCATTT
AGCATTTGTTGATGTAGCAGCTGATCCAGAGTATGTTTTCTATGCCTACAAACGTTTTGGTTATGAGATGACAAATCCGC
ATAATCCAAACACAAAATCAACCATTTCTGATGAACCAATGCTTCCGGTTCGTCCTGTGACAGTAACTAATCCGCAATTT
GAGCGTCATGATATGAAGCCACAAATTATTAAAAACGGCGAAGGTTACCACGAGGATAAACACCGCGAAGATGAAATGAA
GAAAATGGAAGAAGACATCCAAACAAATGAATTCAATAAAAAAGAATCGGATGACGCAGGGAAGTAA

Upstream 100 bases:

>100_bases
TACATAGGAGTTCTAACAAGCTTCTTTCAGCACTCCGGTAATGGTATTTTTGCGCAAAAATACACATTAGAAAACATCAA
AAGGAAAAGAGGGGATTCGG

Downstream 100 bases:

>100_bases
AAAGGGGGGACATAAGGCATGAAATGGAATGAGTTTATCGTAACTGGCGACCCAATGATTTTAGGCGCGCAGATTTCTAT
CGTACTTGTAAGTATTGGTG

Product: AA3-600 quinol oxidase subunit II

Products: NA

Alternate protein names: Quinol oxidase polypeptide II [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSKVLKSLLLTALLGVTGLISGCGDLTVLNPKGPVAKGQSDLIIYSIIFMLVIVLTIFVLFTIMLVKYRERKDISNYEPD
MHGSKKLEIFWTLIPVAIVIALAIPTVKTIYAGEEAPKVTSHKDPIVIYATSADWKWIFSYPDESIETVNYVNIPTDRPV
LFKLTSADTMTSFWVPQLGGQKYAMSGMTMNLYLQADEVGTYKGRNANFNGEGFADQRFDVVAQSEKDFKKWAKETKASS
PVITQDIYDRLLIPGSSKKKTYSGTHLAFVDVAADPEYVFYAYKRFGYEMTNPHNPNTKSTISDEPMLPVRPVTVTNPQF
ERHDMKPQIIKNGEGYHEDKHREDEMKKMEEDIQTNEFNKKESDDAGK

Sequences:

>Translated_368_residues
MSKVLKSLLLTALLGVTGLISGCGDLTVLNPKGPVAKGQSDLIIYSIIFMLVIVLTIFVLFTIMLVKYRERKDISNYEPD
MHGSKKLEIFWTLIPVAIVIALAIPTVKTIYAGEEAPKVTSHKDPIVIYATSADWKWIFSYPDESIETVNYVNIPTDRPV
LFKLTSADTMTSFWVPQLGGQKYAMSGMTMNLYLQADEVGTYKGRNANFNGEGFADQRFDVVAQSEKDFKKWAKETKASS
PVITQDIYDRLLIPGSSKKKTYSGTHLAFVDVAADPEYVFYAYKRFGYEMTNPHNPNTKSTISDEPMLPVRPVTVTNPQF
ERHDMKPQIIKNGEGYHEDKHREDEMKKMEEDIQTNEFNKKESDDAGK
>Mature_367_residues
SKVLKSLLLTALLGVTGLISGCGDLTVLNPKGPVAKGQSDLIIYSIIFMLVIVLTIFVLFTIMLVKYRERKDISNYEPDM
HGSKKLEIFWTLIPVAIVIALAIPTVKTIYAGEEAPKVTSHKDPIVIYATSADWKWIFSYPDESIETVNYVNIPTDRPVL
FKLTSADTMTSFWVPQLGGQKYAMSGMTMNLYLQADEVGTYKGRNANFNGEGFADQRFDVVAQSEKDFKKWAKETKASSP
VITQDIYDRLLIPGSSKKKTYSGTHLAFVDVAADPEYVFYAYKRFGYEMTNPHNPNTKSTISDEPMLPVRPVTVTNPQFE
RHDMKPQIIKNGEGYHEDKHREDEMKKMEEDIQTNEFNKKESDDAGK

Specific function: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI1786635, Length=266, Percent_Identity=36.4661654135338, Blast_Score=171, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6226540, Length=220, Percent_Identity=24.5454545454545, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012141
- InterPro:   IPR008972
- InterPro:   IPR006332
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: 1.9.3.-

Molecular weight: Translated: 41571; Mature: 41440

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVLKSLLLTALLGVTGLISGCGDLTVLNPKGPVAKGQSDLIIYSIIFMLVIVLTIFVL
CHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FTIMLVKYRERKDISNYEPDMHGSKKLEIFWTLIPVAIVIALAIPTVKTIYAGEEAPKVT
HHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
SHKDPIVIYATSADWKWIFSYPDESIETVNYVNIPTDRPVLFKLTSADTMTSFWVPQLGG
CCCCCEEEEEECCCCEEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCHHHHCCCCCCC
QKYAMSGMTMNLYLQADEVGTYKGRNANFNGEGFADQRFDVVAQSEKDFKKWAKETKASS
CEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCC
PVITQDIYDRLLIPGSSKKKTYSGTHLAFVDVAADPEYVFYAYKRFGYEMTNPHNPNTKS
CCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEHHHHCCCCCCCCCCCCCC
TISDEPMLPVRPVTVTNPQFERHDMKPQIIKNGEGYHEDKHREDEMKKMEEDIQTNEFNK
CCCCCCCCCEECEEECCCCHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
KESDDAGK
CCCCCCCC
>Mature Secondary Structure 
SKVLKSLLLTALLGVTGLISGCGDLTVLNPKGPVAKGQSDLIIYSIIFMLVIVLTIFVL
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FTIMLVKYRERKDISNYEPDMHGSKKLEIFWTLIPVAIVIALAIPTVKTIYAGEEAPKVT
HHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
SHKDPIVIYATSADWKWIFSYPDESIETVNYVNIPTDRPVLFKLTSADTMTSFWVPQLGG
CCCCCEEEEEECCCCEEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCHHHHCCCCCCC
QKYAMSGMTMNLYLQADEVGTYKGRNANFNGEGFADQRFDVVAQSEKDFKKWAKETKASS
CEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCC
PVITQDIYDRLLIPGSSKKKTYSGTHLAFVDVAADPEYVFYAYKRFGYEMTNPHNPNTKS
CCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEHHHHCCCCCCCCCCCCCC
TISDEPMLPVRPVTVTNPQFERHDMKPQIIKNGEGYHEDKHREDEMKKMEEDIQTNEFNK
CCCCCCCCCEECEEECCCCHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
KESDDAGK
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA