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The map label for this gene is yoeA [H]

Identifier: 226222642

GI number: 226222642

Start: 3121

End: 4464

Strand: Direct

Name: yoeA [H]

Synonym: Lm4b_00003

Alternate gene names: 226222642

Gene position: 3121-4464 (Clockwise)

Preceding gene: 226222641

Following gene: 226222643

Centisome position: 0.11

GC content: 39.36

Gene sequence:

>1344_bases
ATGATGAAAGATATGACAACAGGTAATCCGACAAAATTAATTTTTTTATTCGCGATGCCGATGTTGATTGGAAACTTGTT
TCAGCAATTTTATACGATGATTGATGCTGTTATTGTTGGGAAATTTGTCAGTGTAGATGCGCTGGCTGCTGTTGGAGCGA
CAAATTCGGTCAATTTTTTTATGATTTCTTTGATTATTGGACTTATGAGCGGGATTTCTGTCGTAGTAGCGCAGTATTTT
GGGTTTAAAGATTTTGATCGTTTGAAAGATGTTATTGCAACGGCGACTTATGCGGTGGTTTTTTCGGCGATTATTTTAAC
TGTTGCAGGAGTTTTGCTAGCAAAGCCATTGCTAATTTTACTTAGAACTCCAGCGAATATTTTGGATGATTCTACTATCT
TTTTAACCACTCTTTTTATTGGGATTTTACCGATGAGTCTGTATAACGGAATGGCCGCGATACTTCGGGCGCTTGGAAAT
TCGATTACACCGCTGATTTTTTTAATTTTATCGTCCTTAATGAATATTGCACTTGATTTTTTATTTGTCGTATATATGGA
TATGGGCGTTCGCGGGGCTGCTATTGCGACAGTTCTTTCTCAAACAGCTGCAGCAATTGCCGTTATTTACTATGCTTATC
GCCACGTACCATTTATGCGGATAGAGCGCGCAAAATTCAAGCTTTCCACCCCACTACTTAAAGAAATGGTGCGCATTGGA
CTACCTTCTGGATTACAAGGATCCTTTATTTCTATCGGAAACATGGCTCTTCAAAGTTTAATAAATGGATTTGGTTCATC
GGTCGTTGCGGCATATACGGCGGCGAGTCGAATTGATTCACTTACATATCAACCAGGAATTGCTTTTGGAGCAGCTTCTT
CGATGTTTGCTGGTCAGAACATCGGTGCTGGGAAAATTGACCGCGTTCGCGAAGGTTTTTGGTCGGGAATTAAAGTAGTT
ACAGCTATCAGCATTGGAATAACGATTTTAGTTCAACTTTTCGCTCGGGAGTTTTTATTACTATTTGTTGATTCTAGTGA
GACGGAAGTTATTAATATCGGTGTAAGTTATTTACTTATTGTCTCTTTATTTTATGTCGTAGTAGGAGTTTTATTTGTTG
TTCGAGAAACACTCAGAGGCACCGGAGATGCGATGGTTCCTTTAGCTATGGGGATTTTTGAGTTAGTTTCGAGACTGGTT
ATCGGATTTGTTTTATCGCTTTATATTGGTTACATAGGGCTTTGGTGGGCTACACCAGTTGCGTGGATTACAGCTACGAT
GCTCGGCGTTTGGAGATATAAATCAGGAGCATGGCAAAAAAAGGCAGTTATTAGGCGAAAATAA

Upstream 100 bases:

>100_bases
AAAAGCACATCCGTCTTGGTTTCAAGGCGGATTCTTTTTTTGTTATAGTACAGTTTTTGGATAGAAATGTATATTTATGC
AAACGGAGGTAATTCTTAGC

Downstream 100 bases:

>100_bases
CCATTTTAGTAAAAAAACGCCAGAGAAGCTCATATTTTCTTTTTTTTAATAAATAATATCCCCCCATTAGTTTTGCTAAA
AAAAGCTGAAAAACGAATAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MMKDMTTGNPTKLIFLFAMPMLIGNLFQQFYTMIDAVIVGKFVSVDALAAVGATNSVNFFMISLIIGLMSGISVVVAQYF
GFKDFDRLKDVIATATYAVVFSAIILTVAGVLLAKPLLILLRTPANILDDSTIFLTTLFIGILPMSLYNGMAAILRALGN
SITPLIFLILSSLMNIALDFLFVVYMDMGVRGAAIATVLSQTAAAIAVIYYAYRHVPFMRIERAKFKLSTPLLKEMVRIG
LPSGLQGSFISIGNMALQSLINGFGSSVVAAYTAASRIDSLTYQPGIAFGAASSMFAGQNIGAGKIDRVREGFWSGIKVV
TAISIGITILVQLFAREFLLLFVDSSETEVINIGVSYLLIVSLFYVVVGVLFVVRETLRGTGDAMVPLAMGIFELVSRLV
IGFVLSLYIGYIGLWWATPVAWITATMLGVWRYKSGAWQKKAVIRRK

Sequences:

>Translated_447_residues
MMKDMTTGNPTKLIFLFAMPMLIGNLFQQFYTMIDAVIVGKFVSVDALAAVGATNSVNFFMISLIIGLMSGISVVVAQYF
GFKDFDRLKDVIATATYAVVFSAIILTVAGVLLAKPLLILLRTPANILDDSTIFLTTLFIGILPMSLYNGMAAILRALGN
SITPLIFLILSSLMNIALDFLFVVYMDMGVRGAAIATVLSQTAAAIAVIYYAYRHVPFMRIERAKFKLSTPLLKEMVRIG
LPSGLQGSFISIGNMALQSLINGFGSSVVAAYTAASRIDSLTYQPGIAFGAASSMFAGQNIGAGKIDRVREGFWSGIKVV
TAISIGITILVQLFAREFLLLFVDSSETEVINIGVSYLLIVSLFYVVVGVLFVVRETLRGTGDAMVPLAMGIFELVSRLV
IGFVLSLYIGYIGLWWATPVAWITATMLGVWRYKSGAWQKKAVIRRK
>Mature_447_residues
MMKDMTTGNPTKLIFLFAMPMLIGNLFQQFYTMIDAVIVGKFVSVDALAAVGATNSVNFFMISLIIGLMSGISVVVAQYF
GFKDFDRLKDVIATATYAVVFSAIILTVAGVLLAKPLLILLRTPANILDDSTIFLTTLFIGILPMSLYNGMAAILRALGN
SITPLIFLILSSLMNIALDFLFVVYMDMGVRGAAIATVLSQTAAAIAVIYYAYRHVPFMRIERAKFKLSTPLLKEMVRIG
LPSGLQGSFISIGNMALQSLINGFGSSVVAAYTAASRIDSLTYQPGIAFGAASSMFAGQNIGAGKIDRVREGFWSGIKVV
TAISIGITILVQLFAREFLLLFVDSSETEVINIGVSYLLIVSLFYVVVGVLFVVRETLRGTGDAMVPLAMGIFELVSRLV
IGFVLSLYIGYIGLWWATPVAWITATMLGVWRYKSGAWQKKAVIRRK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=422, Percent_Identity=25.3554502369668, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48541; Mature: 48541

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKDMTTGNPTKLIFLFAMPMLIGNLFQQFYTMIDAVIVGKFVSVDALAAVGATNSVNFF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
MISLIIGLMSGISVVVAQYFGFKDFDRLKDVIATATYAVVFSAIILTVAGVLLAKPLLIL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRTPANILDDSTIFLTTLFIGILPMSLYNGMAAILRALGNSITPLIFLILSSLMNIALDF
HCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LFVVYMDMGVRGAAIATVLSQTAAAIAVIYYAYRHVPFMRIERAKFKLSTPLLKEMVRIG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHC
LPSGLQGSFISIGNMALQSLINGFGSSVVAAYTAASRIDSLTYQPGIAFGAASSMFAGQN
CCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCC
IGAGKIDRVREGFWSGIKVVTAISIGITILVQLFAREFLLLFVDSSETEVINIGVSYLLI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEHHHHHHHH
VSLFYVVVGVLFVVRETLRGTGDAMVPLAMGIFELVSRLVIGFVLSLYIGYIGLWWATPV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWITATMLGVWRYKSGAWQKKAVIRRK
HHHHHHHHHHHHCCCCCHHHHHHHCCC
>Mature Secondary Structure
MMKDMTTGNPTKLIFLFAMPMLIGNLFQQFYTMIDAVIVGKFVSVDALAAVGATNSVNFF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
MISLIIGLMSGISVVVAQYFGFKDFDRLKDVIATATYAVVFSAIILTVAGVLLAKPLLIL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRTPANILDDSTIFLTTLFIGILPMSLYNGMAAILRALGNSITPLIFLILSSLMNIALDF
HCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LFVVYMDMGVRGAAIATVLSQTAAAIAVIYYAYRHVPFMRIERAKFKLSTPLLKEMVRIG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHC
LPSGLQGSFISIGNMALQSLINGFGSSVVAAYTAASRIDSLTYQPGIAFGAASSMFAGQN
CCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCC
IGAGKIDRVREGFWSGIKVVTAISIGITILVQLFAREFLLLFVDSSETEVINIGVSYLLI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEHHHHHHHH
VSLFYVVVGVLFVVRETLRGTGDAMVPLAMGIFELVSRLVIGFVLSLYIGYIGLWWATPV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWITATMLGVWRYKSGAWQKKAVIRRK
HHHHHHHHHHHHCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]