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The map label for this gene is yqgN [H]

Identifier: 225861911

GI number: 225861911

Start: 1953927

End: 1954466

Strand: Reverse

Name: yqgN [H]

Synonym: SPT_2104

Alternate gene names: 225861911

Gene position: 1954466-1953927 (Counterclockwise)

Preceding gene: 225861912

Following gene: 225861910

Centisome position: 92.53

GC content: 42.41

Gene sequence:

>540_bases
ATGAAATCGGAATTACGCAAGCAAGTCTTGCATGAAATGAAGGCTTTATCTCAAGAACAAAAACAGGCTATAGACCAAGC
TTTAACCGAGCGAATTTTACAACACCCCTTTTATCAAGAAGCCAAGGTCATCGCAACCTACCTCTCTTTTTCTCATGAGT
TTCAAACGCGGGAACTGATTGAGCAGGCGCTGAAGGACGGCAAGAAGGTTTTAATACCCAAAACTTATCCCAAGGGGCGC
ATGGACTTTGTAGTCTATGATCCGCAGCAGTTGGTAAAAACTGCCTTTGCCTTACTGGAGCCACAGGGAGATTTGGAAGT
GGTGGATGTATCTCAGATTGATTTGATTCATGTTCCTGGCCTGGCTTTTACGACGGATGGATATCGGATTGGATATGGTG
GAGGTTATTATGACCGCTATCTGGAACATTTTTCTGGTCATACTTTGAGTACGGTTCATCCTTGTCAAATTCAGGACTTT
ATACCTGAAAACCATGATATTCCTGTTCAGGAGGTATTAATTGATGAAGGAAATCTTTGA

Upstream 100 bases:

>100_bases
ATCACCCTCAAATGAGTCCTAAGGAAGAAGTCTTAGCTATTGGGGTGGCTGCGGTGTCTAGTTTCCTGAAAAAGAAGGCA
GCAGAATAGAGGGCTTGTCT

Downstream 100 bases:

>100_bases
TAGACGTTACCCTGTGACGAGTTTCTTCCTCTTAGTGACGGCCTTGGTATTTTTACTAATGTTGGTCACTGCAGGCGGAA
ACTTTGACAGGGCAGATACA

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVIATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGR
MDFVVYDPQQLVKTAFALLEPQGDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
IPENHDIPVQEVLIDEGNL

Sequences:

>Translated_179_residues
MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVIATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGR
MDFVVYDPQQLVKTAFALLEPQGDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
IPENHDIPVQEVLIDEGNL
>Mature_179_residues
MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVIATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGR
MDFVVYDPQQLVKTAFALLEPQGDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
IPENHDIPVQEVLIDEGNL

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=192, Percent_Identity=32.2916666666667, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1789278, Length=168, Percent_Identity=35.7142857142857, Blast_Score=100, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17510857, Length=156, Percent_Identity=35.8974358974359, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI161077430, Length=181, Percent_Identity=28.1767955801105, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 20530; Mature: 20530

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVIATYLSFSHEFQTRELI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHH
EQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQGDLEVVDVSQIDLIHVPG
HHHHHCCCEEECCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECC
LAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDFIPENHDIPVQEVLIDEGNL
EEEECCCEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCHHHHHCCCCCC
>Mature Secondary Structure
MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVIATYLSFSHEFQTRELI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHH
EQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQGDLEVVDVSQIDLIHVPG
HHHHHCCCEEECCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECC
LAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDFIPENHDIPVQEVLIDEGNL
EEEECCCEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]