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The map label for this gene is peb1A [H]

Identifier: 225858444

GI number: 225858444

Start: 600970

End: 601734

Strand: Reverse

Name: peb1A [H]

Synonym: SP70585_0671

Alternate gene names: 225858444

Gene position: 601734-600970 (Counterclockwise)

Preceding gene: 225858445

Following gene: 225858443

Centisome position: 27.54

GC content: 44.31

Gene sequence:

>765_bases
TTGATTAGCCTTTTCGGCCTTGCTGCTGCCAAACCAGTCCAGGCTGATACTAGTATCGCAGACATTCAAAAAAGAGGCGA
ACTGGTTGTCGGTGTCAAACAAGACGTTCCCAATTTTGGTTACAAAGATCCCAAGACCGGTACTTATTCTGGTATCGAAA
CCGACTTGGCCAAGATGGTAGCTGATGAACTCAAGGTCAAGATTCGCTATGTGCCGGTTACAGCACAAACCCGCGGCCCC
CTTCTAGACAATGAACAGGTCGATATGGATATCGCGACCTTTACCATCACGGACGAACGCAAAAAACTCTACAACTTTAC
CAGTCCCTACTACACAGACGCTTCTGGATTTTTGGTCAATAAATCTGCCAAAATCAAAAAGATTGAGGACCTAAACGGCA
AAACCATCGGAGTCGCCCAAGGCTCCATCACCCAACGCCTGATTACTGAACTGGGCAAAAAGAAAGGTCTAACCTTTAAA
TTTGTCGAACTTGGTTCCTACCCAGAATTGATTACTTCCCTGCACGCTCATCGTATCGATGCCTTTTCCGTTGACCGCTC
TATTCTATCTGGCTACACTAATAAACGGACAGCACTACTAGATGATAGTTTCAAGCCATCTGACTACGGTATTGTTACCA
AGAAATCAAATACAGAGCTCAACGACTATCTTGATAACTTGGTTACTAAATGGAGCAAGGATGGTAGTTTGCAGAAACTT
TATGACCGTTACAAGCTCAAACCATCTAGTCATACCGCAGATTAA

Upstream 100 bases:

>100_bases
ACCTCGTGCCCAACAATTCCTCAGCAAAATTATCAACCACGAAAGTGACAAAGTCAAATAAGGAGGCGCCTATGAAAAAA
AATTCTTTTTATCAGCATTA

Downstream 100 bases:

>100_bases
GGAGGATACCCTATGACAGATTTATCATCTTGGACAGCCTATTTTCAGGATTTTGAACAATTTTTCAATGGTTTCCTCTT
TACTCTTGCCCTAGCGATTG

Product: amino acid ABC transporter, amino acid-binding protein

Products: NA

Alternate protein names: CBF1; PEB1 [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGP
LLDNEQVDMDIATFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFK
FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNTELNDYLDNLVTKWSKDGSLQKL
YDRYKLKPSSHTAD

Sequences:

>Translated_254_residues
MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGP
LLDNEQVDMDIATFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFK
FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNTELNDYLDNLVTKWSKDGSLQKL
YDRYKLKPSSHTAD
>Mature_254_residues
MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGP
LLDNEQVDMDIATFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFK
FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNTELNDYLDNLVTKWSKDGSLQKL
YDRYKLKPSSHTAD

Specific function: Common antigen and a major cell adherence molecule. Most probably involved, with PEB1C, in a binding-protein-dependent transport system for an amino acid. May be involved in binding to intestinal cells [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cell surface [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=231, Percent_Identity=29.4372294372294, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786876, Length=245, Percent_Identity=22.8571428571429, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787088, Length=201, Percent_Identity=28.3582089552239, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1787031, Length=204, Percent_Identity=29.9019607843137, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787085, Length=201, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788649, Length=226, Percent_Identity=24.7787610619469, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788648, Length=209, Percent_Identity=24.4019138755981, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 28247; Mature: 28247

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDPKTGTYSGIETDLAKMV
CEEEECCCCCCCCCCCCHHHHHHHCCCEEEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHH
ADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKKLYNFTSPYYTDASGFLVN
HHHHEEEEEEEEEECCCCCCCCCCCCCCEEEEEEEEEHHHHHHHCCCCCCEECCCCEEEE
KSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFKFVELGSYPELITSLHAHRID
CCCCEEEHHCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCC
AFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNTELNDYLDNLVTKWSKDGSLQKL
HHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHH
YDRYKLKPSSHTAD
HHHHCCCCCCCCCC
>Mature Secondary Structure
MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDPKTGTYSGIETDLAKMV
CEEEECCCCCCCCCCCCHHHHHHHCCCEEEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHH
ADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKKLYNFTSPYYTDASGFLVN
HHHHEEEEEEEEEECCCCCCCCCCCCCCEEEEEEEEEHHHHHHHCCCCCCEECCCCEEEE
KSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFKFVELGSYPELITSLHAHRID
CCCCEEEHHCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCC
AFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNTELNDYLDNLVTKWSKDGSLQKL
HHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHH
YDRYKLKPSSHTAD
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204; 1885571 [H]