| Definition | Streptococcus pneumoniae 70585, complete genome. |
|---|---|
| Accession | NC_012468 |
| Length | 2,184,682 |
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The map label for this gene is hsdM [H]
Identifier: 225858347
GI number: 225858347
Start: 516713
End: 518176
Strand: Reverse
Name: hsdM [H]
Synonym: SP70585_0567
Alternate gene names: 225858347
Gene position: 518176-516713 (Counterclockwise)
Preceding gene: 225858348
Following gene: 225858346
Centisome position: 23.72
GC content: 34.56
Gene sequence:
>1464_bases ATGTCAATTACATCATTTGTAAAAAGAATTCAAGATATCACTCGAAACGATGCTGGTGTTAATGGTGATGCTCAACGTAT TGAGCAAATGTCTTGGTTATTATTCTTAAAAATTTATGATAGCCGTGAAATGGTTTGGGAATTAGAAGAAGACGAGTATG AGTCAATTATCCCAGAGGAATTAAAATGGCGAAATTGGGCTCATGCTCAAAATGGGGAACGGGTATTGACAGGCGATGAA TTACTTGATTTTGTCAATAACAAGTTATTCAAAGAGTTGAAAGAGCTTGAAATAACTTCAATTATGCCTATTCGAAAAAC GATTGTTAAATCAGCTTTTGAAGATGCGAACAACTATATGAAAAATGGCGTCTTGTTACGCCAAGTCATCAATGTTATTG ATGAAGTTGATTTCAATAGCCCTGAAGATCGTCATTCGTTTAATGATATTTACGAAAAAATTCTTAAAGATATTCAAAAT GCTGGGAACTCAGGAGAATTTTATACGCCACGTGCAGCGACTGATTTTATTGCCGAAGTTCTTAACCCAAAACTTGGAGA ATCAATGGCAGACCTTGCTTGCGGAACAGGAGGCTTCTTGACTTCGACTCTGAACCGTTTAAGTAGTCAACGTAAAACTA GTGAAGATACCAAAAAATATAATACAGCTGTTTTTGGTATTGAAAAGAAAGCATTTCCTCATCTTTTAGCAGTTACAAAT CTGTTTCTTCACGAAATTGATGACCCTAAAATTGTTCATGGAAATACTTTAGAGAAAAATGTTCGTGAATATACGGATGA TGAAAAATTTGACATTATTATGATGAATCCACCTTTTGGAGGGTCAGAATTAGAAACAATAAAAAATAACTTTCCAGCAG AATTACGGAGTTCTGAAACAGCTGATTTATTTATGGCTGTCATTATGTATCGTTTGAAAGAAAATGGTCGTGTTGGAGTT ATTTTACCTGATGGTTTTCTATTTGGTGAAGGTGTAAAAACTCGCTTGAAACAAAAACTGGTAGATGAGTTCAACTTGCA TACGATTATTAGGTTGCCTCATAGTGTCTTTGCACCGTATACAGGAATCCATACGAACATTCTTTTCTTTGATAAAACAA AGAAAACAGAAGAAACTTGGTTTTATCGTTTAGATATGCCAGATGGTTATAAAAATTTCTCGAAAACTAAGCCGATGAAG TCAGAACACTTCAATCCTGTTCGTGACTGGTGGGAAAATCGTGAAGAGATTCTGGAAGGTAAGTTCTACAAATCTAAATC ATTTACACCTAGTGAATTGGCTGAGTTGAATTATAATTTAGACCAGTGTGGTTTTCCAAAAGAGGAAGAGGAAATCTTAA ATCCCTTTGAGTTGATTCAGAATTATCAAGCGGAAAGAGCAACTTTAAATCATAAGATTGATAATGTATTAGCTGATATT TTGCAGTTGTTGGAGGACAAATAA
Upstream 100 bases:
>100_bases CAAAATCATCAATACTTATTTTGGAGATAAAAAACGATATTTACAAGCAATTAAAGAATTGGAGCAAGAGCTATTTACAG TAGCTTAATGAAAGGAAAGT
Downstream 100 bases:
>100_bases TGACACCAGAACAACTTAAGGCAAGTATTCTCCAAAGAGCGATGGAAGGGAAATTAGTGCCGCAAAATCCCAATGACGAA CCTGCAAGTGAATTATTAAA
Product: type I restriction enzyme
Products: NA
Alternate protein names: M.EcoEI [H]
Number of amino acids: Translated: 487; Mature: 486
Protein sequence:
>487_residues MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREMVWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDE LLDFVNNKLFKELKELEITSIMPIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTKKYNTAVFGIEKKAFPHLLAVTN LFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMNPPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGV ILPDGFLFGEGVKTRLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKNFSKTKPMK SEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEEEILNPFELIQNYQAERATLNHKIDNVLADI LQLLEDK
Sequences:
>Translated_487_residues MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREMVWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDE LLDFVNNKLFKELKELEITSIMPIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTKKYNTAVFGIEKKAFPHLLAVTN LFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMNPPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGV ILPDGFLFGEGVKTRLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKNFSKTKPMK SEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEEEILNPFELIQNYQAERATLNHKIDNVLADI LQLLEDK >Mature_486_residues SITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREMVWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDEL LDFVNNKLFKELKELEITSIMPIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQNA GNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTKKYNTAVFGIEKKAFPHLLAVTNL FLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMNPPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVI LPDGFLFGEGVKTRLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKNFSKTKPMKS EHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEEEILNPFELIQNYQAERATLNHKIDNVLADIL QLLEDK
Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to
COG id: COG0286
COG function: function code V; Type I restriction-modification system methyltransferase subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]
Homologues:
Organism=Escherichia coli, GI1790808, Length=405, Percent_Identity=28.1481481481481, Blast_Score=132, Evalue=4e-32,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR022749 - InterPro: IPR003356 - InterPro: IPR002052 - InterPro: IPR002296 [H]
Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]
EC number: =2.1.1.72 [H]
Molecular weight: Translated: 56480; Mature: 56348
Theoretical pI: Translated: 4.79; Mature: 4.79
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREMVWELEEDEYESIIPEE CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEECCCHHEEECCCHHHHHCCCHH LKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIMPIRKTIVKSAFEDANNYM HHHCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQNAGNSGEFYTPRAATDFIAEV HCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHH LNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTKKYNTAVFGIEKKAFPHLLAVTN HCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCHHHHHHHHHHHH LFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMNPPFGGSELETIKNNFPAELRSSET HHHHHCCCCCEECCCCHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCCHHHCCCCH ADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKTRLKQKLVDEFNLHTIIRLPHSVFAPY HHHHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHHHHHHCCHHHHHCCHHHHCCC TGIHTNILFFDKTKKTEETWFYRLDMPDGYKNFSKTKPMKSEHFNPVRDWWENREEILEG CCCCEEEEEEECCCCCCCEEEEEECCCCCCCHHHHCCCCCHHCCCHHHHHHHCHHHHHCC KFYKSKSFTPSELAELNYNLDQCGFPKEEEEILNPFELIQNYQAERATLNHKIDNVLADI CHHCCCCCCHHHHHHHCCCHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH LQLLEDK HHHHCCC >Mature Secondary Structure SITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREMVWELEEDEYESIIPEE CHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEECCCHHEEECCCHHHHHCCCHH LKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIMPIRKTIVKSAFEDANNYM HHHCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQNAGNSGEFYTPRAATDFIAEV HCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHH LNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTKKYNTAVFGIEKKAFPHLLAVTN HCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCHHHHHHHHHHHH LFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMNPPFGGSELETIKNNFPAELRSSET HHHHHCCCCCEECCCCHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCCHHHCCCCH ADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKTRLKQKLVDEFNLHTIIRLPHSVFAPY HHHHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHHHHHHCCHHHHHCCHHHHCCC TGIHTNILFFDKTKKTEETWFYRLDMPDGYKNFSKTKPMKSEHFNPVRDWWENREEILEG CCCCEEEEEEECCCCCCCEEEEEECCCCCCCHHHHCCCCCHHCCCHHHHHHHCHHHHHCC KFYKSKSFTPSELAELNYNLDQCGFPKEEEEILNPFELIQNYQAERATLNHKIDNVLADI CHHCCCCCCHHHHHHHCCCHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH LQLLEDK HHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8412658 [H]