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The map label for this gene is sorA [H]

Identifier: 225858132

GI number: 225858132

Start: 301228

End: 302031

Strand: Reverse

Name: sorA [H]

Synonym: SP70585_0342

Alternate gene names: 225858132

Gene position: 302031-301228 (Counterclockwise)

Preceding gene: 225858133

Following gene: 225858131

Centisome position: 13.82

GC content: 47.76

Gene sequence:

>804_bases
ATGTCTATTATTTCTATGGTTTTAGTAGTCGTTGTAGCCTTCTTTGCAGGTCTTGAAGGCATCCTCGACCAGTTCCAATT
TCACCAACCACTTGTAGCCTGTACCCTTATTGGGCTTGTAACAGGTCACTTGGAAGCAGGGATTATCCTCGGTGGATCGC
TTCAAATGATTGCCCTTGGTTGGTCAAATATCGGTGCTGCTATCGCTCCTGATGCTGCACTTGCTTCTGTCGCTGCTGCC
ATTATCATGGTTCTTGGTGGTGACTTTACCAAGACTGGTATCGGTGTTGCCCAAGCGGTTGCTATCCCTCTTGCCGTAGC
TGGACTTTTCTTGACAATGATTGTTCGTACAATTTCAGTTGGTTTGGTTCATACTGCAGATGCTGCCGCTAAAAAAGGTG
ACTTCGGCGCTGTGGAGCGTGCGCATTTCATTGCGCTACTCTTCCAAGGACTTCGTATCGCGCTTCCTGCAGCTCTTCTC
CTTATGGTACCAACTGAAACTGTACAAAGTATCCTTAGTGCCATGCCAGACTGGCTCAAAGATGGTATGGCTATCGGTGG
TGGTATGGTCGTTGCCGTTGGTTACGCCATGGTTATCAACATGATGGCAACTCGTGAAGTATGGCCATTCTTCGCTCTTG
GTTTCGTTCTCGCTGCTGTGTCAGATATTACTCTAATCGGATTCGGTGCTATCGGTGTTGCTATCGCTCTTATCTACCTT
CACCTTTCTAAAACTGGTGGAAATGGTGGCGGAGGAGCCGCAACTTCTAACGACCCAATCGGCGATATCCTAGAAGACTA
CTAA

Upstream 100 bases:

>100_bases
TGATGTCCGTAAAGTACCAAATGATTCTAAAAAAGATTTGTTTGACTTGATTAACAAAGCCAATGTCAAATAAGCCATTA
TTTATGAAAGGATTTTAAAC

Downstream 100 bases:

>100_bases
GATAAGAAAGGACTGAAAACATCATGACTGAAAAACTTCAATTAACTAAATCAGATCGTAAAAAAGTTTGGTGGCGTTCA
ACCTTCTTACAAGGGTCTTG

Product: PTS system sorbose-specific IIC component

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Sor; PTS system sorbose-specific EIIC component [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHLEAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAA
IIMVLGGDFTKTGIGVAQAVAIPLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLAAVSDITLIGFGAIGVAIALIYL
HLSKTGGNGGGGAATSNDPIGDILEDY

Sequences:

>Translated_267_residues
MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHLEAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAA
IIMVLGGDFTKTGIGVAQAVAIPLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLAAVSDITLIGFGAIGVAIALIYL
HLSKTGGNGGGGAATSNDPIGDILEDY
>Mature_266_residues
SIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHLEAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAI
IMVLGGDFTKTGIGVAQAVAIPLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALLL
MVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLAAVSDITLIGFGAIGVAIALIYLH
LSKTGGNGGGGAATSNDPIGDILEDY

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3715

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788121, Length=262, Percent_Identity=48.8549618320611, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1789528, Length=255, Percent_Identity=23.1372549019608, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004700
- InterPro:   IPR018404 [H]

Pfam domain/function: PF03609 EII-Sor [H]

EC number: NA

Molecular weight: Translated: 27231; Mature: 27100

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS51106 PTS_EIIC_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHLEAGIILGGSLQMIALG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEC
WSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAIPLAVAGLFLTMIVRTISV
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALLLMVPTETVQSILSAMPDWLK
HHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHH
DGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLAAVSDITLIGFGAIGVAIALIYL
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLSKTGGNGGGGAATSNDPIGDILEDY
HHHCCCCCCCCCCCCCCCCHHHHHHCC
>Mature Secondary Structure 
SIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHLEAGIILGGSLQMIALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEC
WSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAIPLAVAGLFLTMIVRTISV
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALLLMVPTETVQSILSAMPDWLK
HHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHH
DGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLAAVSDITLIGFGAIGVAIALIYL
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLSKTGGNGGGGAATSNDPIGDILEDY
HHHCCCCCCCCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7947968 [H]