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The map label for this gene is ribD

Identifier: 225858039

GI number: 225858039

Start: 211531

End: 212631

Strand: Reverse

Name: ribD

Synonym: SP70585_0241

Alternate gene names: 225858039

Gene position: 212631-211531 (Counterclockwise)

Preceding gene: 225858043

Following gene: 225858038

Centisome position: 9.73

GC content: 36.33

Gene sequence:

>1101_bases
ATGAGCGATTCAAAATATATGAAATTAGCAATAAAACTGGCACAAAAAGGGGCTGGTTACGTCAACCCCAATCCTATGGT
CGGCGCAGTTATTGTAAAAGATAATCACATCATCGGACAAGGTTATCATGAGTTTTTTGGTGGCCCACATGCTGAGAGAA
ATGCTCTTAAAAACTGTAGAGAATCCCCTGTCGGAGCGACGCTTTATGTAACACTTGAACCCTGTTGTCACTTCGGGAAA
ACACCTCCCTGTATAGATGCTATAATCGATAGTGGTATTACAAGAGTAGTCATTGGAAGCCTAGACTGTAATCCTATTGT
ATCTGGAAAAGGAGTAAAGATACTTGAGGAAAATAATCTTCAAGTTACTGTTGGAATTTTAGAAAATGAGTGTCTTAACT
TAATAAAAAGTTTTAGAAAGTATATTACCCAGCATGTACCCTATGTTTTTATGAAATATGCAATGTCAATGGATGGAAAA
ATAGCCACTAAAACAAATCAATCCAAATGGATTACTGAAGAAGAAGCAAGAAAGCATGTGCATCAGTTACGACACCATGT
TAGTGCAATTATGGTGGGAGTCAATACTGTTATTCAAGACGATCCTTTGCTGACATGTAGATTGGAGGAAGGGAAAAATC
CTATCCGTATCATATGCGATACACATTTACGAACTCCTCTTACCTCTAAAATCGTAAAAACAGCAAATGATATTAAAACT
TACATTGCCACTTCCTCTGAAGACAAAAATAAAATGAAGCTATATCAAAATCATGGCTGTGAAATACTTTCCATAAAGAA
AAAAGGCAATCATATAGACTTATCGAGTTTAATGCAACATCTAGGAAACATGCAGATTGATAGCCTAGTTCTAGAAGGGG
GCAGTCTAATGAATTGGAGTGCTTTGGAACAACAAATTGTTGATGAGCTGAAAATATATATTGCATCAAAAATTTTTGGA
GGCAGTGCCAAGTTTCCTGTCGGAGGTGAAGGCATTTCTTTGCCAAATGACGCTATTAGATTGAAACCTTATGCTTTTTC
TCAAATAGGAAATGACTATCTCATAGAAAGTGAAGTGATTTATCCATGTTCACAGGAATAA

Upstream 100 bases:

>100_bases
ATTACTTGTCATTTCAGAGCATTTTTGTTAATCGCATAAGTTTTCTTTTGTATGCCTTGAGTAGTCCCCTATTCAAGGTA
TATTTTTTGGAGGTAGTGAG

Downstream 100 bases:

>100_bases
TTGAAGAAATCGGAAAAGTTGAAAGAATACAGAAAGACTCTCGTAATTGTAAACTATCAATTAAAGCCTCAAAAATATTA
ACGGATATCCATTTAGGCGA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHEFFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGK
TPPCIDAIIDSGITRVVIGSLDCNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRIICDTHLRTPLTSKIVKTANDIKT
YIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSSLMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIASKIFG
GSAKFPVGGEGISLPNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE

Sequences:

>Translated_366_residues
MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHEFFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGK
TPPCIDAIIDSGITRVVIGSLDCNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRIICDTHLRTPLTSKIVKTANDIKT
YIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSSLMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIASKIFG
GSAKFPVGGEGISLPNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE
>Mature_365_residues
SDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHEFFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKT
PPCIDAIIDSGITRVVIGSLDCNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGKI
ATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRIICDTHLRTPLTSKIVKTANDIKTY
IATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSSLMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIASKIFGG
SAKFPVGGEGISLPNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=365, Percent_Identity=38.3561643835616, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI145693172, Length=161, Percent_Identity=32.9192546583851, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40585; Mature: 40453

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHEFFGGPHAERNALKNCR
CCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCHHHHCCCCCHHHHHHHHHH
ESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLDCNPIVSGKGVKILEENNL
CCCCCEEEEEEEEHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCCEECCCCEEEEECCCC
QVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGKIATKTNQSKWITEEEARKHV
EEEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHH
HQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRIICDTHLRTPLTSKIVKTANDIKT
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
YIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSSLMQHLGNMQIDSLVLEGGSLMNWS
HEECCCCCCHHHHHHHCCCCEEEEEECCCCEECHHHHHHHHCCCEEEHEEECCCCCCCHH
ALEQQIVDELKIYIASKIFGGSAKFPVGGEGISLPNDAIRLKPYAFSQIGNDYLIESEVI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCHHHHHCCCCEEEECCEE
YPCSQE
CCCCCC
>Mature Secondary Structure 
SDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHEFFGGPHAERNALKNCR
CCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCHHHHCCCCCHHHHHHHHHH
ESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLDCNPIVSGKGVKILEENNL
CCCCCEEEEEEEEHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCCEECCCCEEEEECCCC
QVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGKIATKTNQSKWITEEEARKHV
EEEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHH
HQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRIICDTHLRTPLTSKIVKTANDIKT
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
YIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSSLMQHLGNMQIDSLVLEGGSLMNWS
HEECCCCCCHHHHHHHCCCCEEEEEECCCCEECHHHHHHHHCCCEEEHEEECCCCCCCHH
ALEQQIVDELKIYIASKIFGGSAKFPVGGEGISLPNDAIRLKPYAFSQIGNDYLIESEVI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCHHHHHCCCCEEEECCEE
YPCSQE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]