Click here to switch to the map view.

The map label for this gene is pgsA [H]

Identifier: 225852218

GI number: 225852218

Start: 704328

End: 704912

Strand: Reverse

Name: pgsA [H]

Synonym: BMEA_A0734

Alternate gene names: 225852218

Gene position: 704912-704328 (Counterclockwise)

Preceding gene: 225852219

Following gene: 225852217

Centisome position: 33.16

GC content: 55.21

Gene sequence:

>585_bases
ATGCAGAAGAATCATACCCTTTCCTTGCCTAATATGCTCACTTACGGACGGATCATCGCCGTTCCGCTCGTGGTGTTGTG
CTTCTTCATCGAAGGACGGCTGGAATCGAGCGACTTTGCACGCTGGACGGCGCTCGGGCTGTTCGCCATTGCGAGCATTA
CCGACTTTTTCGACGGCTATCTCGCCCGCATCTGGAAACAGACTTCCACGATTGGCCGGATGCTGGACCCGATCGCCGAC
AAGCTTCTCGTTTCCGCCATCCTGTTGCTTCTGGCAGCCGATGGTACCATTGCGGGCTGGACGCTCTGGGCTGCGATTAT
CATCCTGTGCCGCGAAATCCTTGTTTCGGGCCTGCGGGAATATCTTGCGGAACTGAAAGTCAGCGTGCCGGTATCACGCC
TTGCCAAGTGGAAAACCACAGCACAGATGGTTGCGCTTGCTTTTCTGCTCGCTGGCCCTGCCGGTGACAAAATCATACCC
TATGTAACGCAGATCGGTATCGGCCTGTTGTGGATTTCGGCCATTCTGACCCTTTATACGGGATGGGACTATTTCCGCGC
TGGCCTCAAACACGTCATGGATTGA

Upstream 100 bases:

>100_bases
GGACATATTAGCGACGTTAGATTCCAGCATAACATATTCGCAGGTGTTGATTTTCTCCGTCATCCCTGTTGATGTGCCAT
CATAACGATGCGGCGGAACA

Downstream 100 bases:

>100_bases
TCTTTTGAGCGTAAAACTCGTCTATTTCGCCTGGGTGCGAGAAAAAATCGGCAAGGGAGAAGAATTCATCGAGCTTCCTG
CCGAAGCTGTTAGCGTCGGG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MQKNHTLSLPNMLTYGRIIAVPLVVLCFFIEGRLESSDFARWTALGLFAIASITDFFDGYLARIWKQTSTIGRMLDPIAD
KLLVSAILLLLAADGTIAGWTLWAAIIILCREILVSGLREYLAELKVSVPVSRLAKWKTTAQMVALAFLLAGPAGDKIIP
YVTQIGIGLLWISAILTLYTGWDYFRAGLKHVMD

Sequences:

>Translated_194_residues
MQKNHTLSLPNMLTYGRIIAVPLVVLCFFIEGRLESSDFARWTALGLFAIASITDFFDGYLARIWKQTSTIGRMLDPIAD
KLLVSAILLLLAADGTIAGWTLWAAIIILCREILVSGLREYLAELKVSVPVSRLAKWKTTAQMVALAFLLAGPAGDKIIP
YVTQIGIGLLWISAILTLYTGWDYFRAGLKHVMD
>Mature_194_residues
MQKNHTLSLPNMLTYGRIIAVPLVVLCFFIEGRLESSDFARWTALGLFAIASITDFFDGYLARIWKQTSTIGRMLDPIAD
KLLVSAILLLLAADGTIAGWTLWAAIIILCREILVSGLREYLAELKVSVPVSRLAKWKTTAQMVALAFLLAGPAGDKIIP
YVTQIGIGLLWISAILTLYTGWDYFRAGLKHVMD

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI188536108, Length=210, Percent_Identity=29.5238095238095, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1788220, Length=190, Percent_Identity=41.0526315789474, Blast_Score=123, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6320059, Length=167, Percent_Identity=35.9281437125749, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21460; Mature: 21460

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKNHTLSLPNMLTYGRIIAVPLVVLCFFIEGRLESSDFARWTALGLFAIASITDFFDGY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LARIWKQTSTIGRMLDPIADKLLVSAILLLLAADGTIAGWTLWAAIIILCREILVSGLRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YLAELKVSVPVSRLAKWKTTAQMVALAFLLAGPAGDKIIPYVTQIGIGLLWISAILTLYT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GWDYFRAGLKHVMD
CHHHHHHHHHHHCC
>Mature Secondary Structure
MQKNHTLSLPNMLTYGRIIAVPLVVLCFFIEGRLESSDFARWTALGLFAIASITDFFDGY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LARIWKQTSTIGRMLDPIADKLLVSAILLLLAADGTIAGWTLWAAIIILCREILVSGLRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YLAELKVSVPVSRLAKWKTTAQMVALAFLLAGPAGDKIIPYVTQIGIGLLWISAILTLYT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GWDYFRAGLKHVMD
CHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA