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The map label for this gene is 225851740

Identifier: 225851740

GI number: 225851740

Start: 223525

End: 224493

Strand: Reverse

Name: 225851740

Synonym: BMEA_A0220

Alternate gene names: NA

Gene position: 224493-223525 (Counterclockwise)

Preceding gene: 225851741

Following gene: 225851739

Centisome position: 10.56

GC content: 57.48

Gene sequence:

>969_bases
ATGAAGAAAATGGCATTTGCCGCGCTGTTCGGCGCGGTGCTCAGCTTCGCCTCGTCGGCGGAAGCCAATGACAAGCTGAA
GCTCATTCTCGACTGGTATGTGAACCCCGACCATGGGCCGATTATCATTGCCAACAAGCTCGGCTATTTCAGGCAAGCGG
GGCTGGACGTGGATATCGTCGCGCCTGCCGATGCTTCCGTGCCCACGAAAATGGTTGCTGCCGGCCAGGCCGATCTTGCC
GTTTCCTATCAGCAGCAGGTGCATCTGCAAGTACATGAGGGCCTGCCGGTCATCCGCGTCGGCACGCTGATCGATTCGCC
GCTCAATTGCCTGATGACCCGCGATGACGGATCGGTGAATGCAATCGCCGACCTGAAAGGCAAAAAGATCGGCTATTCGG
TTGCAGGCGTTGAGGAAACCCTGCTCGGCACCATTCTCGGCCAGCATGGCGTCAAGCTTTCCGATGTCGAACTCATCAAT
GTCAATTTCTCGCTGGCGCCAGCGCTCATGTCGAAACAGGTGGATGCGGTGATAGGCGCCTATCGCAATGTGGAACTGAA
CCAGATGGCCGTCGAGGGCGTGGCGGGCAAGTGCTTCTTCGTGGAGGAGGAAGGCGTGCCGGTCTATGACGAGCTGGTCT
ATGTCGCAAATAGCGACAAGCTTGATGCGGCAGAGAGGCAAAAGATTTCCCGCTTCCTCGCCGCCACCGAAAAGGCCGCG
CAATATATCGTCAATCACCCGGAGAAGAGTTACGAGATCTTTTCCTCCTACAGCACGGAACTGGAGGACGAATTGAACCA
GCGCGCGTGGAAAGACACGGTTGCCCGCTTCTCGCGCGCACCAGCAAGCCTCGATCATGGCCGCTGGAGCCGCTATGAAT
CCTATCTGAAGGAGCATGGCCTCGTGCCCTCCATCCTGCCGGTCGAAAAATTGGCCATCGACGTCAATGCGGAAGGGAGC
AAGACATGA

Upstream 100 bases:

>100_bases
CCGACATCACGCTTCACGCCGACCCGGCCGCGCGCGTTCGCGAATGGATCGCCGTCACCCGGCCTTTCGTCGCCTGAAAT
CACAGCTCTGGAGGAAGATC

Downstream 100 bases:

>100_bases
ACCTGCCACAGCCGCATTACTCATCCGAACTTTTCACGCGCCTTCGCACTGCCACGCTTGCCGACTGGAAGCCCTATATC
GAGCACGACTTCGTGCGGGG

Product: NMT1/THI5 like domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKKMAFAALFGAVLSFASSAEANDKLKLILDWYVNPDHGPIIIANKLGYFRQAGLDVDIVAPADASVPTKMVAAGQADLA
VSYQQQVHLQVHEGLPVIRVGTLIDSPLNCLMTRDDGSVNAIADLKGKKIGYSVAGVEETLLGTILGQHGVKLSDVELIN
VNFSLAPALMSKQVDAVIGAYRNVELNQMAVEGVAGKCFFVEEEGVPVYDELVYVANSDKLDAAERQKISRFLAATEKAA
QYIVNHPEKSYEIFSSYSTELEDELNQRAWKDTVARFSRAPASLDHGRWSRYESYLKEHGLVPSILPVEKLAIDVNAEGS
KT

Sequences:

>Translated_322_residues
MKKMAFAALFGAVLSFASSAEANDKLKLILDWYVNPDHGPIIIANKLGYFRQAGLDVDIVAPADASVPTKMVAAGQADLA
VSYQQQVHLQVHEGLPVIRVGTLIDSPLNCLMTRDDGSVNAIADLKGKKIGYSVAGVEETLLGTILGQHGVKLSDVELIN
VNFSLAPALMSKQVDAVIGAYRNVELNQMAVEGVAGKCFFVEEEGVPVYDELVYVANSDKLDAAERQKISRFLAATEKAA
QYIVNHPEKSYEIFSSYSTELEDELNQRAWKDTVARFSRAPASLDHGRWSRYESYLKEHGLVPSILPVEKLAIDVNAEGS
KT
>Mature_322_residues
MKKMAFAALFGAVLSFASSAEANDKLKLILDWYVNPDHGPIIIANKLGYFRQAGLDVDIVAPADASVPTKMVAAGQADLA
VSYQQQVHLQVHEGLPVIRVGTLIDSPLNCLMTRDDGSVNAIADLKGKKIGYSVAGVEETLLGTILGQHGVKLSDVELIN
VNFSLAPALMSKQVDAVIGAYRNVELNQMAVEGVAGKCFFVEEEGVPVYDELVYVANSDKLDAAERQKISRFLAATEKAA
QYIVNHPEKSYEIFSSYSTELEDELNQRAWKDTVARFSRAPASLDHGRWSRYESYLKEHGLVPSILPVEKLAIDVNAEGS
KT

Specific function: Probably involved in thiamine biosynthesis [H]

COG id: COG0715

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NMT1 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322616, Length=292, Percent_Identity=26.027397260274, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6319957, Length=292, Percent_Identity=26.027397260274, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321050, Length=292, Percent_Identity=26.027397260274, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323997, Length=292, Percent_Identity=26.027397260274, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 35099; Mature: 35099

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMAFAALFGAVLSFASSAEANDKLKLILDWYVNPDHGPIIIANKLGYFRQAGLDVDIV
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCEEEECCCCHHHHCCCCEEEE
APADASVPTKMVAAGQADLAVSYQQQVHLQVHEGLPVIRVGTLIDSPLNCLMTRDDGSVN
CCCCCCCCHHHHHCCCCCEEEEEHHEEEEECCCCCCEEEEHHHHCCCCCEEEECCCCCEE
AIADLKGKKIGYSVAGVEETLLGTILGQHGVKLSDVELINVNFSLAPALMSKQVDAVIGA
EEEECCCCCCCEEECCHHHHHHHHHHHHCCCEECCEEEEEECCHHHHHHHHHHHHHHHHH
YRNVELNQMAVEGVAGKCFFVEEEGVPVYDELVYVANSDKLDAAERQKISRFLAATEKAA
HCCCCHHHHHHCCCCCEEEEEECCCCCHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QYIVNHPEKSYEIFSSYSTELEDELNQRAWKDTVARFSRAPASLDHGRWSRYESYLKEHG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCC
LVPSILPVEKLAIDVNAEGSKT
CCCCCCCHHHEEEEECCCCCCC
>Mature Secondary Structure
MKKMAFAALFGAVLSFASSAEANDKLKLILDWYVNPDHGPIIIANKLGYFRQAGLDVDIV
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCEEEECCCCHHHHCCCCEEEE
APADASVPTKMVAAGQADLAVSYQQQVHLQVHEGLPVIRVGTLIDSPLNCLMTRDDGSVN
CCCCCCCCHHHHHCCCCCEEEEEHHEEEEECCCCCCEEEEHHHHCCCCCEEEECCCCCEE
AIADLKGKKIGYSVAGVEETLLGTILGQHGVKLSDVELINVNFSLAPALMSKQVDAVIGA
EEEECCCCCCCEEECCHHHHHHHHHHHHCCCEECCEEEEEECCHHHHHHHHHHHHHHHHH
YRNVELNQMAVEGVAGKCFFVEEEGVPVYDELVYVANSDKLDAAERQKISRFLAATEKAA
HCCCCHHHHHHCCCCCEEEEEECCCCCHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QYIVNHPEKSYEIFSSYSTELEDELNQRAWKDTVARFSRAPASLDHGRWSRYESYLKEHG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCC
LVPSILPVEKLAIDVNAEGSKT
CCCCCCCHHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]