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The map label for this gene is rbtR [H]

Identifier: 225686111

GI number: 225686111

Start: 244034

End: 245089

Strand: Direct

Name: rbtR [H]

Synonym: BMEA_B0264

Alternate gene names: 225686111

Gene position: 244034-245089 (Clockwise)

Preceding gene: 225686110

Following gene: 225686113

Centisome position: 20.58

GC content: 56.63

Gene sequence:

>1056_bases
ATGCACATCAGCAGGAAAAAGGCGACGATCTATGATCTTTCCGTTTTGTCGGGAAGCTCGCCTTCGACTGTGAGCGCCGT
GCTGAACGGCACATGGCGGAAGCGGCGTATCAGTCAGGCTACGGCGGAGGCCATATTGCAACTGGCCGATCAGCATGCCT
ATACCGCCAACCGGCAGGCACAAGGCCTGCGTCATTCCCGCTCCGGCCTGGTGGGGCTTTTGCTCCCGTTGCATGACAAT
CGCTTTTTCTCCGCTATGGCGCAGATTTTTGAGGCACATGTACGCGCGCGCAGCTTTTGCCCCGTGGTGGTGAGCGCAAG
CCGCGACCCGGAAGAAGAGCGCGAGACGGCGGAAACCCTCATTTCCTATGCCATTGACGAGCTGTTTATTTGTGGCGCCA
CTGATCCGGACGGCTTGCATGAGCTCTGCGAAAAAGCGGCCCTGCCACATGTGAATATCGACCTGCCTGGCTCCAGGGCT
CCTTCCGTCACCACGGATAATTTCGCGGGCGGCAAGATGCTCACTGCGGCCATCATCGAATATTTTGGCGAAGAGGCGCC
TTTGCAGCCTGAAGATCTTTGTCTTTTTGGCGGACGAAACGATGAATCGACCCGCCAGCGCATTTGCGGTTTCCATCAGG
TGAAGCAGACCGTGCTGGGGGCCGACCCGGAAGGCTGCGTGTTCAAGACCGGCTATTCGCCTGCAAATACTCTGGTTGCG
CTCAACGATTATCGCGCGCGGCATGGCAGGCTGCCGCGCGGTCTCTTCGTCAATTCCTCCATCAATCTGGAAGGGTTGCT
ACGCTTCATGGCAGAGCATCCGGGCGAGCCGCTCAATGATATTGTCATTGGCTGTTACGACTATGATCCCTTCGCCTCGT
TCCTGCCCTTTCCGGTTATTTCTATCCTTCAGGATGTGGAAGGCATGATTGCAAAAGCCTTCGACCTGATGGAACGGCGC
GTGACGGAACCGGAATTGCACCTCATCATGCCGAAGCTTATTGCGCCGCGTTCCGCTATCACCGGGCCACTCGATAGTTT
CAAGGATATCAAATAA

Upstream 100 bases:

>100_bases
GCCGAAGGCGAGGACTGAATACCTCGCCTCCACAGCCTCAAGAAACGTATTTCACTTTCTCTTCGGGCCGACTATTCCTA
TAGCTCGAAAAGGAGAGGGT

Downstream 100 bases:

>100_bases
ATAGGCATGTAAGCAGGTATGGCCAATACTTTCGCCCGAAGCCTCTTCGGGCTTTTTGTGCCCGCTTTCGCCATATATCA
TTTTGAACCGGGTTGCAGAT

Product: Ribitol operon repressor

Products: NA

Alternate protein names: Rbt operon repressor [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MHISRKKATIYDLSVLSGSSPSTVSAVLNGTWRKRRISQATAEAILQLADQHAYTANRQAQGLRHSRSGLVGLLLPLHDN
RFFSAMAQIFEAHVRARSFCPVVVSASRDPEEERETAETLISYAIDELFICGATDPDGLHELCEKAALPHVNIDLPGSRA
PSVTTDNFAGGKMLTAAIIEYFGEEAPLQPEDLCLFGGRNDESTRQRICGFHQVKQTVLGADPEGCVFKTGYSPANTLVA
LNDYRARHGRLPRGLFVNSSINLEGLLRFMAEHPGEPLNDIVIGCYDYDPFASFLPFPVISILQDVEGMIAKAFDLMERR
VTEPELHLIMPKLIAPRSAITGPLDSFKDIK

Sequences:

>Translated_351_residues
MHISRKKATIYDLSVLSGSSPSTVSAVLNGTWRKRRISQATAEAILQLADQHAYTANRQAQGLRHSRSGLVGLLLPLHDN
RFFSAMAQIFEAHVRARSFCPVVVSASRDPEEERETAETLISYAIDELFICGATDPDGLHELCEKAALPHVNIDLPGSRA
PSVTTDNFAGGKMLTAAIIEYFGEEAPLQPEDLCLFGGRNDESTRQRICGFHQVKQTVLGADPEGCVFKTGYSPANTLVA
LNDYRARHGRLPRGLFVNSSINLEGLLRFMAEHPGEPLNDIVIGCYDYDPFASFLPFPVISILQDVEGMIAKAFDLMERR
VTEPELHLIMPKLIAPRSAITGPLDSFKDIK
>Mature_351_residues
MHISRKKATIYDLSVLSGSSPSTVSAVLNGTWRKRRISQATAEAILQLADQHAYTANRQAQGLRHSRSGLVGLLLPLHDN
RFFSAMAQIFEAHVRARSFCPVVVSASRDPEEERETAETLISYAIDELFICGATDPDGLHELCEKAALPHVNIDLPGSRA
PSVTTDNFAGGKMLTAAIIEYFGEEAPLQPEDLCLFGGRNDESTRQRICGFHQVKQTVLGADPEGCVFKTGYSPANTLVA
LNDYRARHGRLPRGLFVNSSINLEGLLRFMAEHPGEPLNDIVIGCYDYDPFASFLPFPVISILQDVEGMIAKAFDLMERR
VTEPELHLIMPKLIAPRSAITGPLDSFKDIK

Specific function: Repressor for the genes of the ribitol operon. Binds D- ribulose as an inducer [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786268, Length=338, Percent_Identity=23.0769230769231, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787906, Length=214, Percent_Identity=28.0373831775701, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787948, Length=349, Percent_Identity=21.7765042979943, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790194, Length=329, Percent_Identity=22.4924012158055, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI48994940, Length=215, Percent_Identity=26.046511627907, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38634; Mature: 38634

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHISRKKATIYDLSVLSGSSPSTVSAVLNGTWRKRRISQATAEAILQLADQHAYTANRQA
CCCCCCCCEEEEEHEECCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
QGLRHSRSGLVGLLLPLHDNRFFSAMAQIFEAHVRARSFCPVVVSASRDPEEERETAETL
HHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
ISYAIDELFICGATDPDGLHELCEKAALPHVNIDLPGSRAPSVTTDNFAGGKMLTAAIIE
HHHHHHHHEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
YFGEEAPLQPEDLCLFGGRNDESTRQRICGFHQVKQTVLGADPEGCVFKTGYSPANTLVA
HHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEE
LNDYRARHGRLPRGLFVNSSINLEGLLRFMAEHPGEPLNDIVIGCYDYDPFASFLPFPVI
ECCHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCCCCHHHEEEEECCCHHHHHHHHHHH
SILQDVEGMIAKAFDLMERRVTEPELHLIMPKLIAPRSAITGPLDSFKDIK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCCHHHHCCCC
>Mature Secondary Structure
MHISRKKATIYDLSVLSGSSPSTVSAVLNGTWRKRRISQATAEAILQLADQHAYTANRQA
CCCCCCCCEEEEEHEECCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
QGLRHSRSGLVGLLLPLHDNRFFSAMAQIFEAHVRARSFCPVVVSASRDPEEERETAETL
HHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
ISYAIDELFICGATDPDGLHELCEKAALPHVNIDLPGSRAPSVTTDNFAGGKMLTAAIIE
HHHHHHHHEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
YFGEEAPLQPEDLCLFGGRNDESTRQRICGFHQVKQTVLGADPEGCVFKTGYSPANTLVA
HHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEE
LNDYRARHGRLPRGLFVNSSINLEGLLRFMAEHPGEPLNDIVIGCYDYDPFASFLPFPVI
ECCHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCCCCHHHEEEEECCCHHHHHHHHHHH
SILQDVEGMIAKAFDLMERRVTEPELHLIMPKLIAPRSAITGPLDSFKDIK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3891331 [H]