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The map label for this gene is groES

Identifier: 225686051

GI number: 225686051

Start: 180671

End: 180967

Strand: Reverse

Name: groES

Synonym: BMEA_B0196

Alternate gene names: 225686051

Gene position: 180967-180671 (Counterclockwise)

Preceding gene: 225686053

Following gene: 225686050

Centisome position: 15.26

GC content: 59.6

Gene sequence:

>297_bases
ATGGCTGATATCAAGTTCCGCCCGCTTCATGACCGCGTCGTCGTTCGCCGCGTCGAATCGGAAGCCAAGACTGCCGGCGG
CATCATCATCCCTGACACTGCCAAGGAAAAGCCGCAGGAAGGCGAAGTCGTTGCAGCCGGTGCTGGCGCTCGTGACGAAG
CTGGCAAGCTGGTTCCGCTGGATGTCAAGGCTGGCGACCGCGTTCTGTTCGGCAAGTGGTCGGGCACCGAAGTCAAGATC
GGCGGCGAAGACCTGCTGATCATGAAGGAATCCGACATTCTGGGTATTGTCGGCTAA

Upstream 100 bases:

>100_bases
CTCAAGAACCACGTTAGCACTCGGACGAATAGAGTGCTAACAGCGGGCCATTCCGGTCCGCGTAACAGGGTTCAACGTCT
ATAACACCAAGGGTTATACC

Downstream 100 bases:

>100_bases
AAAATTCCTTTTGCGTTGCTTCACGCAACCAGAATTCCATTCACAGTACAACATTTACAAATCTGACCGGGATATTCCCA
GGAGAGTAAAATGGCTGCAA

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MADIKFRPLHDRVVVRRVESEAKTAGGIIIPDTAKEKPQEGEVVAAGAGARDEAGKLVPLDVKAGDRVLFGKWSGTEVKI
GGEDLLIMKESDILGIVG

Sequences:

>Translated_98_residues
MADIKFRPLHDRVVVRRVESEAKTAGGIIIPDTAKEKPQEGEVVAAGAGARDEAGKLVPLDVKAGDRVLFGKWSGTEVKI
GGEDLLIMKESDILGIVG
>Mature_97_residues
ADIKFRPLHDRVVVRRVESEAKTAGGIIIPDTAKEKPQEGEVVAAGAGARDEAGKLVPLDVKAGDRVLFGKWSGTEVKIG
GEDLLIMKESDILGIVG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=91, Percent_Identity=40.6593406593407, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=51.5789473684211, Blast_Score=89, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17555568, Length=91, Percent_Identity=50.5494505494505, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324594, Length=89, Percent_Identity=40.4494382022472, Blast_Score=73, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21356029, Length=93, Percent_Identity=43.010752688172, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358317, Length=92, Percent_Identity=42.3913043478261, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_BRUA1 (B2SCZ5)

Other databases:

- EMBL:   M82975
- EMBL:   M83930
- EMBL:   CP000888
- PIR:   A43827
- RefSeq:   YP_001932145.1
- ProteinModelPortal:   B2SCZ5
- SMR:   B2SCZ5
- GeneID:   6326464
- GenomeReviews:   CP000888_GR
- KEGG:   bmc:BAbS19_II01800
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- ProtClustDB:   PRK00364
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10393; Mature: 10262

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIKFRPLHDRVVVRRVESEAKTAGGIIIPDTAKEKPQEGEVVAAGAGARDEAGKLVPL
CCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEE
DVKAGDRVLFGKWSGTEVKIGGEDLLIMKESDILGIVG
ECCCCCEEEEECCCCCEEEECCCEEEEEECCCEEEEEC
>Mature Secondary Structure 
ADIKFRPLHDRVVVRRVESEAKTAGGIIIPDTAKEKPQEGEVVAAGAGARDEAGKLVPL
CCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEE
DVKAGDRVLFGKWSGTEVKIGGEDLLIMKESDILGIVG
ECCCCCEEEEECCCCCEEEECCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1347461; 1350274