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The map label for this gene is ttdR [H]

Identifier: 225686033

GI number: 225686033

Start: 161912

End: 162832

Strand: Reverse

Name: ttdR [H]

Synonym: BMEA_B0178

Alternate gene names: 225686033

Gene position: 162832-161912 (Counterclockwise)

Preceding gene: 225686034

Following gene: 225686032

Centisome position: 13.74

GC content: 61.24

Gene sequence:

>921_bases
ATGATGAGCAGCCTGGCGGATATGGAGATATTTGCCCGCGTCGTGGCCACGGGCAGCATGTCGGCCGCTGCGCGCGATCT
TGGTCTTTCACCGGCCGTCGTTTCCAAGCGCCTGGGGCGGCTGGAAGAAAGGCTTGGAACACGCCTTCTCCAGCGCACGA
CGCGCCAGATCGCGCTGACAGAGGCCGGTCAGGGCTATCATGAGCGGGTGCTGGCCATTCTCGCCAATATTGAGGAGGCG
GAAGCCTTCGTCGCCCGCCGCTCCGCTGATGCGCGCGGTACGCTGAAGATTTCAGCTCCCACCACTTTCGGGCGGATGCA
TATCGCGCCCTATCTTGTGCCTTTCATGCGCGCCAATGCCGATCTCACGGTCAATATGCAATTGAGCGACGAAATGGTGG
ATATTGTCGGTGATGGCTACGACCTTGCAATCCGCATCGGCGAACTTTCCGATTCCACGCTCGTTGCCCGCCGCCTCGCG
CCCGTGCGCCGCATTTTCGTTGCCACACCCCGCTACCTCAAGGAGCGCGGCACCCCGCAGACGATCGAAGATTTGCAGGA
TCATATCTGCCTTGCGCCGCACAATAACGACCCCTGGCGGCTGGAGGGGCCGAAAGGCCCCATCGTCATCCGCCCGACCG
GCCCCTTGCAGACCAATTCCAGCGAAATCGTGCGTGAAGCCGTGCTTGCCGGTCTTGGCATTGCGCAACGCTCCACCTGG
GACGTCGGGCCGGAACTGGCCGCCGGCAAGCTTGTGCAGGTGCTGCCCGATTATGCGGCCTCACGCAATGTAGCAATCCA
CGCCGTCTACCCCTCGAAGCAATTCCTGCCTGCCAAGGTGCGGCTTTTCATCGATTATCTCGCAGATCTCTACGGCCCTG
TTCCCTATTGGGAAAGCGGCACCTTTCCTGAGGAGAATTGA

Upstream 100 bases:

>100_bases
TGCACAGCCTGCTGCCCGCACGCTAGAGCTTAGTCTGGCCGGAGTGAAACAAAGATCAACAGGATTATGCTTCAAGCGGC
AGGAGCAGGATGATACGAGC

Downstream 100 bases:

>100_bases
TCGACACATCCGTATGTTTCGTTGCGGCGCTTACGTTTTTTCTTTTGCATCTCGTCGGACCACCGTTGCCCGGCACCGTC
CTAAGGGCTACCTTGCCGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MMSSLADMEIFARVVATGSMSAAARDLGLSPAVVSKRLGRLEERLGTRLLQRTTRQIALTEAGQGYHERVLAILANIEEA
EAFVARRSADARGTLKISAPTTFGRMHIAPYLVPFMRANADLTVNMQLSDEMVDIVGDGYDLAIRIGELSDSTLVARRLA
PVRRIFVATPRYLKERGTPQTIEDLQDHICLAPHNNDPWRLEGPKGPIVIRPTGPLQTNSSEIVREAVLAGLGIAQRSTW
DVGPELAAGKLVQVLPDYAASRNVAIHAVYPSKQFLPAKVRLFIDYLADLYGPVPYWESGTFPEEN

Sequences:

>Translated_306_residues
MMSSLADMEIFARVVATGSMSAAARDLGLSPAVVSKRLGRLEERLGTRLLQRTTRQIALTEAGQGYHERVLAILANIEEA
EAFVARRSADARGTLKISAPTTFGRMHIAPYLVPFMRANADLTVNMQLSDEMVDIVGDGYDLAIRIGELSDSTLVARRLA
PVRRIFVATPRYLKERGTPQTIEDLQDHICLAPHNNDPWRLEGPKGPIVIRPTGPLQTNSSEIVREAVLAGLGIAQRSTW
DVGPELAAGKLVQVLPDYAASRNVAIHAVYPSKQFLPAKVRLFIDYLADLYGPVPYWESGTFPEEN
>Mature_306_residues
MMSSLADMEIFARVVATGSMSAAARDLGLSPAVVSKRLGRLEERLGTRLLQRTTRQIALTEAGQGYHERVLAILANIEEA
EAFVARRSADARGTLKISAPTTFGRMHIAPYLVPFMRANADLTVNMQLSDEMVDIVGDGYDLAIRIGELSDSTLVARRLA
PVRRIFVATPRYLKERGTPQTIEDLQDHICLAPHNNDPWRLEGPKGPIVIRPTGPLQTNSSEIVREAVLAGLGIAQRSTW
DVGPELAAGKLVQVLPDYAASRNVAIHAVYPSKQFLPAKVRLFIDYLADLYGPVPYWESGTFPEEN

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=286, Percent_Identity=39.1608391608392, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=38.013698630137, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1786401, Length=298, Percent_Identity=34.5637583892617, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=34.2465753424658, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=32.312925170068, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=30.3448275862069, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787589, Length=289, Percent_Identity=26.2975778546713, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789173, Length=285, Percent_Identity=27.3684210526316, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786448, Length=282, Percent_Identity=27.3049645390071, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788706, Length=297, Percent_Identity=23.2323232323232, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790011, Length=294, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33614; Mature: 33614

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSLADMEIFARVVATGSMSAAARDLGLSPAVVSKRLGRLEERLGTRLLQRTTRQIALT
CCCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
EAGQGYHERVLAILANIEEAEAFVARRSADARGTLKISAPTTFGRMHIAPYLVPFMRANA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
DLTVNMQLSDEMVDIVGDGYDLAIRIGELSDSTLVARRLAPVRRIFVATPRYLKERGTPQ
CEEEEEEECHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCH
TIEDLQDHICLAPHNNDPWRLEGPKGPIVIRPTGPLQTNSSEIVREAVLAGLGIAQRSTW
HHHHHHHCEEECCCCCCCEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCC
DVGPELAAGKLVQVLPDYAASRNVAIHAVYPSKQFLPAKVRLFIDYLADLYGPVPYWESG
CCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
TFPEEN
CCCCCC
>Mature Secondary Structure
MMSSLADMEIFARVVATGSMSAAARDLGLSPAVVSKRLGRLEERLGTRLLQRTTRQIALT
CCCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
EAGQGYHERVLAILANIEEAEAFVARRSADARGTLKISAPTTFGRMHIAPYLVPFMRANA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
DLTVNMQLSDEMVDIVGDGYDLAIRIGELSDSTLVARRLAPVRRIFVATPRYLKERGTPQ
CEEEEEEECHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCH
TIEDLQDHICLAPHNNDPWRLEGPKGPIVIRPTGPLQTNSSEIVREAVLAGLGIAQRSTW
HHHHHHHCEEECCCCCCCEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCC
DVGPELAAGKLVQVLPDYAASRNVAIHAVYPSKQFLPAKVRLFIDYLADLYGPVPYWESG
CCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
TFPEEN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]