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The map label for this gene is ygbM [H]

Identifier: 225686005

GI number: 225686005

Start: 139060

End: 139845

Strand: Reverse

Name: ygbM [H]

Synonym: BMEA_B0148

Alternate gene names: 225686005

Gene position: 139845-139060 (Counterclockwise)

Preceding gene: 225686006

Following gene: 225686004

Centisome position: 11.8

GC content: 55.47

Gene sequence:

>786_bases
ATGCCGCGTTTTGCTGCCAATCTGTCGACGATGTTTAACGAGGTGCCATTCCTCGAACGTTTTAGACTGGCTGCCGAAGC
AGGTTTTGGCGGCGTCGAGTTTCTGTTTCCTTATGACTTCGACGCTGATGTCATTGCCAGGGAATTGAAGCAGCACAATC
TCACGCAGGTTCTTTTCAACATGCCTCCCGGCGATTGGGCTGCGGGCGAACGCGGCATGGCAGCTATTTCGGGTCGCGAA
CAGGAATTCCGCGACAATGTCGATATCGCCCTGCATTATGCATTGGCGCTGGATTGCAGGACGCTTCACGCCATGTCCGG
CATCACGGAAGGGCTGGACCGGAAAGCCTGCGAGGAAACCTTTATCGAAAACTTCCGCTATGCGGCAGACAAGCTTGCTC
CGCACGGCATCACGGTGCTGGTCGAGCCCCTCAATACGCGCAATATGCCCGGCTATTTCATCGTGCATCAACTGGAAGCC
GTTGGCCTCGTAAAGAGGGTCAACCGCCCCAATGTCGCCGTGCAGCTCGATCTCTATCATGCCCAGATCATGGATGGCGA
CCTGACCCGCCTGATCGAGAAAATGAACGGTGCATTCAGCCATGTTCAAATTGCATCCGTTCCCGACCGGCATGAGCCGG
ATGAAGGCGAATTGAACTATCCATATCTTTTCTCGGTCCTGGAGAGTGTCGGCTATCGGGGATGGGTGGGATGCGAATAT
AATCCGCGGGGCAAAACGGAAAGCGGCCTCGCCTGGTTTGCCCCATACCGGGATCAAAGCGCATGA

Upstream 100 bases:

>100_bases
TCGGAAAACCATTATCGCTTGCACTGAAATCCGGAAATTTCGGCACTGAGGCTTTCTTCTTTGAAGCCCAAAAGATTGCC
AATCAGGAAGGAGATAAATA

Downstream 100 bases:

>100_bases
TACCGGCTGAACGGCAGGCTCTGATTGTCAGCCGCCTTTCGGCGCGCGGCATCTTGAGCATTGCGGAACTGGCCGAAATG
CTGGGCGTATCGCCAATGAC

Product: AP endonuclease, family 2

Products: 2-hydroxy-3-oxopropanoate

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MPRFAANLSTMFNEVPFLERFRLAAEAGFGGVEFLFPYDFDADVIARELKQHNLTQVLFNMPPGDWAAGERGMAAISGRE
QEFRDNVDIALHYALALDCRTLHAMSGITEGLDRKACEETFIENFRYAADKLAPHGITVLVEPLNTRNMPGYFIVHQLEA
VGLVKRVNRPNVAVQLDLYHAQIMDGDLTRLIEKMNGAFSHVQIASVPDRHEPDEGELNYPYLFSVLESVGYRGWVGCEY
NPRGKTESGLAWFAPYRDQSA

Sequences:

>Translated_261_residues
MPRFAANLSTMFNEVPFLERFRLAAEAGFGGVEFLFPYDFDADVIARELKQHNLTQVLFNMPPGDWAAGERGMAAISGRE
QEFRDNVDIALHYALALDCRTLHAMSGITEGLDRKACEETFIENFRYAADKLAPHGITVLVEPLNTRNMPGYFIVHQLEA
VGLVKRVNRPNVAVQLDLYHAQIMDGDLTRLIEKMNGAFSHVQIASVPDRHEPDEGELNYPYLFSVLESVGYRGWVGCEY
NPRGKTESGLAWFAPYRDQSA
>Mature_260_residues
PRFAANLSTMFNEVPFLERFRLAAEAGFGGVEFLFPYDFDADVIARELKQHNLTQVLFNMPPGDWAAGERGMAAISGREQ
EFRDNVDIALHYALALDCRTLHAMSGITEGLDRKACEETFIENFRYAADKLAPHGITVLVEPLNTRNMPGYFIVHQLEAV
GLVKRVNRPNVAVQLDLYHAQIMDGDLTRLIEKMNGAFSHVQIASVPDRHEPDEGELNYPYLFSVLESVGYRGWVGCEYN
PRGKTESGLAWFAPYRDQSA

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=265, Percent_Identity=44.9056603773585, Blast_Score=213, Evalue=1e-55,
Organism=Homo sapiens, GI300068964, Length=243, Percent_Identity=44.0329218106996, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI1789095, Length=258, Percent_Identity=53.8759689922481, Blast_Score=294, Evalue=3e-81,
Organism=Escherichia coli, GI1786718, Length=258, Percent_Identity=46.5116279069767, Blast_Score=248, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17552022, Length=240, Percent_Identity=34.5833333333333, Blast_Score=170, Evalue=8e-43,
Organism=Drosophila melanogaster, GI17530883, Length=256, Percent_Identity=33.984375, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: 5.3.1.22

Molecular weight: Translated: 29405; Mature: 29273

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFAANLSTMFNEVPFLERFRLAAEAGFGGVEFLFPYDFDADVIARELKQHNLTQVLFN
CCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCHHHHEEE
MPPGDWAAGERGMAAISGREQEFRDNVDIALHYALALDCRTLHAMSGITEGLDRKACEET
CCCCCCCCCCCCCCHHCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIENFRYAADKLAPHGITVLVEPLNTRNMPGYFIVHQLEAVGLVKRVNRPNVAVQLDLYH
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHCCCCCEEEEEEEEE
AQIMDGDLTRLIEKMNGAFSHVQIASVPDRHEPDEGELNYPYLFSVLESVGYRGWVGCEY
EECCCCHHHHHHHHHCCCHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEECCCC
NPRGKTESGLAWFAPYRDQSA
CCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
PRFAANLSTMFNEVPFLERFRLAAEAGFGGVEFLFPYDFDADVIARELKQHNLTQVLFN
CCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCHHHHEEE
MPPGDWAAGERGMAAISGREQEFRDNVDIALHYALALDCRTLHAMSGITEGLDRKACEET
CCCCCCCCCCCCCCHHCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIENFRYAADKLAPHGITVLVEPLNTRNMPGYFIVHQLEAVGLVKRVNRPNVAVQLDLYH
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHCCCCCEEEEEEEEE
AQIMDGDLTRLIEKMNGAFSHVQIASVPDRHEPDEGELNYPYLFSVLESVGYRGWVGCEY
EECCCCHHHHHHHHHCCCHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEECCCC
NPRGKTESGLAWFAPYRDQSA
CCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxypyruvate

Specific reaction: hydroxypyruvate = 2-hydroxy-3-oxopropanoate; Other Name(s): hydroxypyruvate ketol-isomerase

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]