Click here to switch to the map view.

The map label for this gene is emrK [H]

Identifier: 225685979

GI number: 225685979

Start: 116000

End: 117241

Strand: Reverse

Name: emrK [H]

Synonym: BMEA_B0120

Alternate gene names: 225685979

Gene position: 117241-116000 (Counterclockwise)

Preceding gene: 225685982

Following gene: 225685978

Centisome position: 9.89

GC content: 59.34

Gene sequence:

>1242_bases
ATGTGCTGTGCAGAAAGTTCACTCATGTCCGCCCCGAAATCCGTTGATAAAGCTGATATTCGTCCATTTCCGACCGCCAA
AACCGTTGCGCCGCTCCATCAGCCTGCAACGAATGAAGCGCCTGCCAATGAAAGAACGCAGCCCCACGCCGTTCCGGACG
AAGCCGTATCCGCCAAGGGCGGCGCGAAGAAAGGCTTCGGCAAGCGCGTCGACCTGCCCAGCCTTGTAGCCGTCGCTGCC
ATAGGCGCGCTCTGGTATGGCTATAACTGGTGGACCGTCGGGCGCTTCATGGTTTCGACAGACGATGCCTATGTTCAGGG
CGACATTGCCTCCATCGCACCCAAGGTCACCGGCTATATTGAAAACATCCCCGTAGCCGCAAACCAGCAGGTCAAGGCCG
GCGATGTGATCTTCCAGCTCGATGCGGGCGACTATCAGATCGCGCTTGACGAAGCCAATGCCAAGCTGGCCACGCAAAAA
GAAACGCTCATCCGCATCCAGGCCCAGACCGATGCCGCCAAGGCCGCGCTGTTGCAGGCAAATGCCGATCAGCAGGCGGC
CAAGGCCGTGCTGCTCAACGCGCAGAGCACCATGGCTCGCGTGCAGAAGCTGCATGAAACCCGTTTCGTCGCGCAATCCG
AACTCGACAATGCCCAGTCCGCCCTGGACCAGGCCCGCGCCAGGCTGGCCGGGGTAGATGCGCAAATTGCATCCGCCAAG
GCCAATATTTCCGTTCTCGAAGCGCAATATAATGAAGCGGCAAGCTCTACTAAATCGCTGGAACTTGCCCGCGATAAGGC
TGCACGCGATCTTTCGTTTACGAGCCTGCGCGCGCCTTTCGACGGTGTGATCGGCAATCTTTCCGGCAAGAAGGGCGACC
TCGTTGCCCCCGGCCAGAAGATCGCGGCGCTCGTGCCGGTCGACCAGCTTTATATCGATGCGAATTTCAAGGAAACCCAA
CTCGCCCACATCAAGGTTGGCGAGACGGCGCATATCTATGTCGATGCGATCGACGGCACGAAGTTTGACGGCAAGGTAGC
CTCCATTGCTCCGGCTTCCGGTGCGGTGTTCTCGCTACTGCCGCCGGAAAACGCCACCGGGAATTTCACCAAGGTCGTGC
AGCGCGTTCCGGTTCGCATCACCATTCCGAAAGAAGCATTTGAATCCGGCAAGATCCGTGCGGGCCTCAGCGTCATTGTT
GACGTGGACACGCGCACCGCGCCGGACCAGACGGCAAACTGA

Upstream 100 bases:

>100_bases
AAAGCAGGACTCTTAACTTTTTTCGAACCAAACGGTTCGATGCCTCTTGATATGAGCATCTCATTGATCTAAGTCAACAT
CGAACCGAACGGTTCAATCC

Downstream 100 bases:

>100_bases
CTGGAACAGCAAAACATTCAGAACCGAATGGCGAAGCCTGAAAGCCTGAACGGGCCGGGCATTGCCGTTTTCTCTTCCCG
GAGCGCGTCAATATGGCCGC

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MCCAESSLMSAPKSVDKADIRPFPTAKTVAPLHQPATNEAPANERTQPHAVPDEAVSAKGGAKKGFGKRVDLPSLVAVAA
IGALWYGYNWWTVGRFMVSTDDAYVQGDIASIAPKVTGYIENIPVAANQQVKAGDVIFQLDAGDYQIALDEANAKLATQK
ETLIRIQAQTDAAKAALLQANADQQAAKAVLLNAQSTMARVQKLHETRFVAQSELDNAQSALDQARARLAGVDAQIASAK
ANISVLEAQYNEAASSTKSLELARDKAARDLSFTSLRAPFDGVIGNLSGKKGDLVAPGQKIAALVPVDQLYIDANFKETQ
LAHIKVGETAHIYVDAIDGTKFDGKVASIAPASGAVFSLLPPENATGNFTKVVQRVPVRITIPKEAFESGKIRAGLSVIV
DVDTRTAPDQTAN

Sequences:

>Translated_413_residues
MCCAESSLMSAPKSVDKADIRPFPTAKTVAPLHQPATNEAPANERTQPHAVPDEAVSAKGGAKKGFGKRVDLPSLVAVAA
IGALWYGYNWWTVGRFMVSTDDAYVQGDIASIAPKVTGYIENIPVAANQQVKAGDVIFQLDAGDYQIALDEANAKLATQK
ETLIRIQAQTDAAKAALLQANADQQAAKAVLLNAQSTMARVQKLHETRFVAQSELDNAQSALDQARARLAGVDAQIASAK
ANISVLEAQYNEAASSTKSLELARDKAARDLSFTSLRAPFDGVIGNLSGKKGDLVAPGQKIAALVPVDQLYIDANFKETQ
LAHIKVGETAHIYVDAIDGTKFDGKVASIAPASGAVFSLLPPENATGNFTKVVQRVPVRITIPKEAFESGKIRAGLSVIV
DVDTRTAPDQTAN
>Mature_413_residues
MCCAESSLMSAPKSVDKADIRPFPTAKTVAPLHQPATNEAPANERTQPHAVPDEAVSAKGGAKKGFGKRVDLPSLVAVAA
IGALWYGYNWWTVGRFMVSTDDAYVQGDIASIAPKVTGYIENIPVAANQQVKAGDVIFQLDAGDYQIALDEANAKLATQK
ETLIRIQAQTDAAKAALLQANADQQAAKAVLLNAQSTMARVQKLHETRFVAQSELDNAQSALDQARARLAGVDAQIASAK
ANISVLEAQYNEAASSTKSLELARDKAARDLSFTSLRAPFDGVIGNLSGKKGDLVAPGQKIAALVPVDQLYIDANFKETQ
LAHIKVGETAHIYVDAIDGTKFDGKVASIAPASGAVFSLLPPENATGNFTKVVQRVPVRITIPKEAFESGKIRAGLSVIV
DVDTRTAPDQTAN

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=355, Percent_Identity=32.6760563380282, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1789041, Length=371, Percent_Identity=33.4231805929919, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1790519, Length=300, Percent_Identity=32, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87081951, Length=315, Percent_Identity=27.3015873015873, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789637, Length=328, Percent_Identity=26.8292682926829, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790024, Length=246, Percent_Identity=28.4552845528455, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790012, Length=259, Percent_Identity=27.7992277992278, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081796, Length=186, Percent_Identity=25.2688172043011, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43684; Mature: 43684

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCCAESSLMSAPKSVDKADIRPFPTAKTVAPLHQPATNEAPANERTQPHAVPDEAVSAKG
CCCCCCHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCC
GAKKGFGKRVDLPSLVAVAAIGALWYGYNWWTVGRFMVSTDDAYVQGDIASIAPKVTGYI
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEEECCHHHHCHHHHHHH
ENIPVAANQQVKAGDVIFQLDAGDYQIALDEANAKLATQKETLIRIQAQTDAAKAALLQA
HCCCCCCCCCEECCCEEEEECCCCEEEEEECCCCCEEECCEEEEEEEECCCHHHHHHHHC
NADQQAAKAVLLNAQSTMARVQKLHETRFVAQSELDNAQSALDQARARLAGVDAQIASAK
CCCHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
ANISVLEAQYNEAASSTKSLELARDKAARDLSFTSLRAPFDGVIGNLSGKKGDLVAPGQK
CCEEEEEEHHHHHHCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHCCCCCCCCCEECCCCC
IAALVPVDQLYIDANFKETQLAHIKVGETAHIYVDAIDGTKFDGKVASIAPASGAVFSLL
EEEEECEEEEEEECCCCCCEEEEEEECCEEEEEEEECCCCCCCCEEEEECCCCCCEEEEE
PPENATGNFTKVVQRVPVRITIPKEAFESGKIRAGLSVIVDVDTRTAPDQTAN
CCCCCCCHHHHHHHHCCEEEEECHHHHHCCCEEECEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MCCAESSLMSAPKSVDKADIRPFPTAKTVAPLHQPATNEAPANERTQPHAVPDEAVSAKG
CCCCCCHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCC
GAKKGFGKRVDLPSLVAVAAIGALWYGYNWWTVGRFMVSTDDAYVQGDIASIAPKVTGYI
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEEECCHHHHCHHHHHHH
ENIPVAANQQVKAGDVIFQLDAGDYQIALDEANAKLATQKETLIRIQAQTDAAKAALLQA
HCCCCCCCCCEECCCEEEEECCCCEEEEEECCCCCEEECCEEEEEEEECCCHHHHHHHHC
NADQQAAKAVLLNAQSTMARVQKLHETRFVAQSELDNAQSALDQARARLAGVDAQIASAK
CCCHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
ANISVLEAQYNEAASSTKSLELARDKAARDLSFTSLRAPFDGVIGNLSGKKGDLVAPGQK
CCEEEEEEHHHHHHCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHCCCCCCCCCEECCCCC
IAALVPVDQLYIDANFKETQLAHIKVGETAHIYVDAIDGTKFDGKVASIAPASGAVFSLL
EEEEECEEEEEEECCCCCCEEEEEEECCEEEEEEEECCCCCCCCEEEEECCCCCCEEEEE
PPENATGNFTKVVQRVPVRITIPKEAFESGKIRAGLSVIVDVDTRTAPDQTAN
CCCCCCCHHHHHHHHCCEEEEECHHHHHCCCEEECEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]