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The map label for this gene is virB2

Identifier: 225685935

GI number: 225685935

Start: 65774

End: 66091

Strand: Reverse

Name: virB2

Synonym: BMEA_B0072

Alternate gene names: 225685935

Gene position: 66091-65774 (Counterclockwise)

Preceding gene: 225685936

Following gene: 225685934

Centisome position: 5.57

GC content: 56.29

Gene sequence:

>318_bases
ATGAAAACCGCTTCCCCCAGCAAGAAGTCGCTGTCGCGGATTCTACCTCACCTACTGCTGGCCCTCATTGTCTCCATCGC
TGCAATCGAGCCTAACCTGGCGCACGCCAACGGTGGCCTCGATAAGGTAAATACAAGCATGCAAAAAGTGCTGGACTTGC
TAAGCGGCGTATCGATCACCATCGTTACCATAGCCATCATCTGGTCCGGTTACAAGATGGCATTCCGGCACGCCCGCTTC
ATGGATGTAGTGCCGGTGCTGGGCGGCGCCCTGGTGGTTGGCGCTGCCGCCGAAATTGCCTCTTACCTGCTTAGGTAA

Upstream 100 bases:

>100_bases
GCAAGACAAATCTTTGGAGGAACCAAGATGAATAGACATTGAGCAAGCAGACCGTGCAGAAATCCATGAATACACTTCAT
CGACATAAGGAATAAAGATC

Downstream 100 bases:

>100_bases
AGGGACACAGATCATGACAACGGCACCACAGGAATCCAACGCACGAAGCGCAGGTTATCGCGGCGATCCAATATTCAAGG
GCTGTACACGGCCAGCCATG

Product: conjugal transfer protein TrbC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MKTASPSKKSLSRILPHLLLALIVSIAAIEPNLAHANGGLDKVNTSMQKVLDLLSGVSITIVTIAIIWSGYKMAFRHARF
MDVVPVLGGALVVGAAAEIASYLLR

Sequences:

>Translated_105_residues
MKTASPSKKSLSRILPHLLLALIVSIAAIEPNLAHANGGLDKVNTSMQKVLDLLSGVSITIVTIAIIWSGYKMAFRHARF
MDVVPVLGGALVVGAAAEIASYLLR
>Mature_105_residues
MKTASPSKKSLSRILPHLLLALIVSIAAIEPNLAHANGGLDKVNTSMQKVLDLLSGVSITIVTIAIIWSGYKMAFRHARF
MDVVPVLGGALVVGAAAEIASYLLR

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ptlA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VIRB2_BRUA2 (Q2YIT6)

Other databases:

- EMBL:   AF226278
- EMBL:   AM040265
- RefSeq:   YP_418312.1
- STRING:   Q2YIT6
- GeneID:   3827981
- GenomeReviews:   AM040265_GR
- KEGG:   bmf:BAB2_0067
- HOGENOM:   HBG683898
- OMA:   MAFAHAR
- ProtClustDB:   CLSK898648
- BioCyc:   BMEL359391:BAB2_0067-MONOMER
- GO:   GO:0009405
- InterPro:   IPR007039

Pfam domain/function: PF04956 TrbC

EC number: NA

Molecular weight: Translated: 11107; Mature: 11107

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d7d2654)-; HASH(0x1f1b54a4)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTASPSKKSLSRILPHLLLALIVSIAAIEPNLAHANGGLDKVNTSMQKVLDLLSGVSIT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
IVTIAIIWSGYKMAFRHARFMDVVPVLGGALVVGAAAEIASYLLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MKTASPSKKSLSRILPHLLLALIVSIAAIEPNLAHANGGLDKVNTSMQKVLDLLSGVSIT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
IVTIAIIWSGYKMAFRHARFMDVVPVLGGALVVGAAAEIASYLLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10940027