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The map label for this gene is virB11 [H]

Identifier: 225685926

GI number: 225685926

Start: 56825

End: 57913

Strand: Reverse

Name: virB11 [H]

Synonym: BMEA_B0063

Alternate gene names: 225685926

Gene position: 57913-56825 (Counterclockwise)

Preceding gene: 225685927

Following gene: 225685925

Centisome position: 4.89

GC content: 58.59

Gene sequence:

>1089_bases
ATGATGTCAAACCGAAGTGACTTTATTGTGCCTGACGAGGCGGCTGTCAAACGGGCGGCCTCGGTCAATTTCCATCTGGA
ACCGCTGCGCCCTTGGTTGGACGATCCGCAGATCACCGAAGTTTGCGTGAACCGGCCGGGCGAAGTGTTCTGCGAGCGAG
CAAGCGCGTGGGAATACTATGCGGTGCCAAACCTCGACTATGAACACCTGATTTCGCTGGGAACCGCCACCGCGCGGTTT
GTGGATCAGGATATTTCGGACAGCCGACCGGTGCTGTCTGCGATCCTGCCGATGGGTGAGCGCATTCAGATTGTGCGCCC
GCCCGCATGTGAGCACGGCACCATCTCGGTGACGATCCGCAAGCCGTCTTTCACCCGGCGCACACTGGAAGACTATGCGC
AGCAGGGCTTTTTCAAACACGTCAGACCCATGAGTAAGAGCCTGACGCCGTTTGAACAGGAACTGCTCGCATTGAAGGAA
GCTGGTGATTACATGAGCTTCCTGCGGCGGGCGGTACAGCTTGAAAGGGTGATCGTCGTCGCCGGCGAGACGGGATCAGG
CAAGACCACACTGATGAAAGCGCTGATGCAGGAAATTCCGTTCGATCAGCGCCTGATCACCATCGAGGACGTACCGGAGT
TGTTCTTGCCGGACCATCCGAACCACGTCCACCTGTTTTATCCGAGCGAAGCGAAGGAAGAAGAAAACGCACCAGTGACG
GCCGCCACGCTACTGCGGAGCTGCCTGCGCATGAAACCGACGCGCATCCTGCTTGCCGAGCTGCGCGGCGGCGAGACTTA
CGATTTCATCAACGTGGCCGCGTCCGGCCATGGCGGCAGCATCACCAGTTGCCATGCCGGTTCGTGCGAACTGACTTTCG
AGCGGCTGGCATTGATGGTGTTGCAGAACCGCCAGGGCCGCCAGTTGCCATACGAGATCATCCGCCGGCTGCTCTATCTG
GTGGTGGATGTCGTCGTGCACGTCCACAATGGCGTGCACGACGGCACTGGCCGCCATATATCTGAAGTTTGGTACGACCC
GAATACAAAACGGGCACTGTCACTGCAACACAGTGAGAAGGCGCAATGA

Upstream 100 bases:

>100_bases
GCCTTGAAGGATACGATCAACATTCCGCCGACACTGTACAAGAACCAGGGCGAAGAGATCGGCATCTATATCGCCCGCGA
CCTAGATTTTTCGAGTGTGT

Downstream 100 bases:

>100_bases
AGCTGCAACTTTCACCCCTGCACCAGAATGCGCGCAGGGCGTCAGCTTCTCGCCAACACAAGCTCTGTGCAGCCGCATAT
CACGCATATGCTGCACAAAT

Product: P-type DNA transfer ATPase VirB11

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MMSNRSDFIVPDEAAVKRAASVNFHLEPLRPWLDDPQITEVCVNRPGEVFCERASAWEYYAVPNLDYEHLISLGTATARF
VDQDISDSRPVLSAILPMGERIQIVRPPACEHGTISVTIRKPSFTRRTLEDYAQQGFFKHVRPMSKSLTPFEQELLALKE
AGDYMSFLRRAVQLERVIVVAGETGSGKTTLMKALMQEIPFDQRLITIEDVPELFLPDHPNHVHLFYPSEAKEEENAPVT
AATLLRSCLRMKPTRILLAELRGGETYDFINVAASGHGGSITSCHAGSCELTFERLALMVLQNRQGRQLPYEIIRRLLYL
VVDVVVHVHNGVHDGTGRHISEVWYDPNTKRALSLQHSEKAQ

Sequences:

>Translated_362_residues
MMSNRSDFIVPDEAAVKRAASVNFHLEPLRPWLDDPQITEVCVNRPGEVFCERASAWEYYAVPNLDYEHLISLGTATARF
VDQDISDSRPVLSAILPMGERIQIVRPPACEHGTISVTIRKPSFTRRTLEDYAQQGFFKHVRPMSKSLTPFEQELLALKE
AGDYMSFLRRAVQLERVIVVAGETGSGKTTLMKALMQEIPFDQRLITIEDVPELFLPDHPNHVHLFYPSEAKEEENAPVT
AATLLRSCLRMKPTRILLAELRGGETYDFINVAASGHGGSITSCHAGSCELTFERLALMVLQNRQGRQLPYEIIRRLLYL
VVDVVVHVHNGVHDGTGRHISEVWYDPNTKRALSLQHSEKAQ
>Mature_362_residues
MMSNRSDFIVPDEAAVKRAASVNFHLEPLRPWLDDPQITEVCVNRPGEVFCERASAWEYYAVPNLDYEHLISLGTATARF
VDQDISDSRPVLSAILPMGERIQIVRPPACEHGTISVTIRKPSFTRRTLEDYAQQGFFKHVRPMSKSLTPFEQELLALKE
AGDYMSFLRRAVQLERVIVVAGETGSGKTTLMKALMQEIPFDQRLITIEDVPELFLPDHPNHVHLFYPSEAKEEENAPVT
AATLLRSCLRMKPTRILLAELRGGETYDFINVAASGHGGSITSCHAGSCELTFERLALMVLQNRQGRQLPYEIIRRLLYL
VVDVVVHVHNGVHDGTGRHISEVWYDPNTKRALSLQHSEKAQ

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. Virb11 is essential for pathogenesis in mice but is not required for intracellular survival [H]

COG id: COG0630

COG function: function code NU; Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014155
- InterPro:   IPR002078
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 40855; Mature: 40855

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00675 SIGMA54_INTERACT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSNRSDFIVPDEAAVKRAASVNFHLEPLRPWLDDPQITEVCVNRPGEVFCERASAWEYY
CCCCCCCEECCCHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHCCCHHHHHHHCCCCEEE
AVPNLDYEHLISLGTATARFVDQDISDSRPVLSAILPMGERIQIVRPPACEHGTISVTIR
ECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCEEEEEEE
KPSFTRRTLEDYAQQGFFKHVRPMSKSLTPFEQELLALKEAGDYMSFLRRAVQLERVIVV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEE
AGETGSGKTTLMKALMQEIPFDQRLITIEDVPELFLPDHPNHVHLFYPSEAKEEENAPVT
ECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHCCCCCCCEEEEECCCCCCCCCCCCHH
AATLLRSCLRMKPTRILLAELRGGETYDFINVAASGHGGSITSCHAGSCELTFERLALMV
HHHHHHHHHHCCCHHEEEEECCCCCEEEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHH
LQNRQGRQLPYEIIRRLLYLVVDVVVHVHNGVHDGTGRHISEVWYDPNTKRALSLQHSEK
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEECCCCCCEEEECCCCC
AQ
CC
>Mature Secondary Structure
MMSNRSDFIVPDEAAVKRAASVNFHLEPLRPWLDDPQITEVCVNRPGEVFCERASAWEYY
CCCCCCCEECCCHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHCCCHHHHHHHCCCCEEE
AVPNLDYEHLISLGTATARFVDQDISDSRPVLSAILPMGERIQIVRPPACEHGTISVTIR
ECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCEEEEEEE
KPSFTRRTLEDYAQQGFFKHVRPMSKSLTPFEQELLALKEAGDYMSFLRRAVQLERVIVV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEE
AGETGSGKTTLMKALMQEIPFDQRLITIEDVPELFLPDHPNHVHLFYPSEAKEEENAPVT
ECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHCCCCCCCEEEEECCCCCCCCCCCCHH
AATLLRSCLRMKPTRILLAELRGGETYDFINVAASGHGGSITSCHAGSCELTFERLALMV
HHHHHHHHHHCCCHHEEEEECCCCCEEEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHH
LQNRQGRQLPYEIIRRLLYLVVDVVVHVHNGVHDGTGRHISEVWYDPNTKRALSLQHSEK
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEECCCCCCEEEECCCCC
AQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10940027 [H]