| Definition | Brucella melitensis ATCC 23457 chromosome chromosome II, complete sequence. |
|---|---|
| Accession | NC_012442 |
| Length | 1,185,518 |
Click here to switch to the map view.
The map label for this gene is entA [H]
Identifier: 225685881
GI number: 225685881
Start: 10398
End: 11174
Strand: Reverse
Name: entA [H]
Synonym: BMEA_B0015
Alternate gene names: 225685881
Gene position: 11174-10398 (Counterclockwise)
Preceding gene: 225685882
Following gene: 225685879
Centisome position: 0.94
GC content: 61.52
Gene sequence:
>777_bases ATGGTCGAGGCAAAATCCTATCCGGCAAGCTGGCGCTTTGCCGGAAAACGGGTGATCGTCACCGGCGCCGCACAAGGCAT CGGCCGCCGTGTGGCGGAGCATTTTCTGGCCGAAGGCGCAACCGTCATCGGGCTGGATCGTCAGGCTGGCGAGGCGGATG CGCCCTTTCGGCTGATCCGGCTCGATATTACCGATGCGGCGGAAGTCCGCGCGGTCAGCGACGGTCTCAAGGCGGAAGGC AAACCCCTCGATATTCTGGTCAATGTCGCGGGTGTGCTGAAGCTTGGCAACAGCGACAGGCTGAGCGCGGAAGATTGGAA AACCTGCATGGATGTCAATGCCAGCGGTCCCTTCCATCTTCTCAGCCAATGGGTTCCCGTTTTCCGCGACCAGCGCCACG GCGCCATTGTCAATGTCGCCTCCAACGCCGCCCATGTGCCGCGCCTCAACATGGCGGCCTATTGCGCATCGAAAGCAGCA TTGGCAAGCTTCAGCCATTGCGTGGCGCTGGAGCTTGCACCCTATGGCGTGCGCTGCAATGTCGTCTCGCCGGGATCAAC CCGCACAGCCATGCTGGGCGCCATGCTGAACGATCCTTCCGGCGAAGCGCAACTGGTGCGTGGCCTGCCGGAACAGTTCA AGCTTGGCATACCGCTCGGCAAGATCGCGATCCCGGACGATATCGCCAATGTCATCCTGTTTCTGGCGTCCGATCAGGCC GGGCATGTGACGATGCAGGATATTGTCGTGGATGGCGGAGCAACCCTTGGCGCATGA
Upstream 100 bases:
>100_bases AAGAGCGCGGCGTGGCCGTGGGCTTTGATGATCTTGCCCGCGTGCCAACCCTTGCGGCCTGGTGGGACCTGATCGAAACA AAGCAGAAGGCAGCCGCCTG
Downstream 100 bases:
>100_bases GACCGCGTGGCTTGCGCCAGGCGCCCACGGCGTTTCGGTCATAACGCCGTGGGCCGATCTGGCCGCAGACTGCTGTTTCG TCATGGCCCGCTATTCGGCC
Product: 2,3-dihydroxybenzoate-2,3-dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 258; Mature: 258
Protein sequence:
>258_residues MVEAKSYPASWRFAGKRVIVTGAAQGIGRRVAEHFLAEGATVIGLDRQAGEADAPFRLIRLDITDAAEVRAVSDGLKAEG KPLDILVNVAGVLKLGNSDRLSAEDWKTCMDVNASGPFHLLSQWVPVFRDQRHGAIVNVASNAAHVPRLNMAAYCASKAA LASFSHCVALELAPYGVRCNVVSPGSTRTAMLGAMLNDPSGEAQLVRGLPEQFKLGIPLGKIAIPDDIANVILFLASDQA GHVTMQDIVVDGGATLGA
Sequences:
>Translated_258_residues MVEAKSYPASWRFAGKRVIVTGAAQGIGRRVAEHFLAEGATVIGLDRQAGEADAPFRLIRLDITDAAEVRAVSDGLKAEG KPLDILVNVAGVLKLGNSDRLSAEDWKTCMDVNASGPFHLLSQWVPVFRDQRHGAIVNVASNAAHVPRLNMAAYCASKAA LASFSHCVALELAPYGVRCNVVSPGSTRTAMLGAMLNDPSGEAQLVRGLPEQFKLGIPLGKIAIPDDIANVILFLASDQA GHVTMQDIVVDGGATLGA >Mature_258_residues MVEAKSYPASWRFAGKRVIVTGAAQGIGRRVAEHFLAEGATVIGLDRQAGEADAPFRLIRLDITDAAEVRAVSDGLKAEG KPLDILVNVAGVLKLGNSDRLSAEDWKTCMDVNASGPFHLLSQWVPVFRDQRHGAIVNVASNAAHVPRLNMAAYCASKAA LASFSHCVALELAPYGVRCNVVSPGSTRTAMLGAMLNDPSGEAQLVRGLPEQFKLGIPLGKIAIPDDIANVILFLASDQA GHVTMQDIVVDGGATLGA
Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=32.9365079365079, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=32.03125, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=28.2442748091603, Blast_Score=101, Evalue=8e-22, Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=28.0632411067194, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=30.46875, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI19923817, Length=272, Percent_Identity=28.3088235294118, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=29.9145299145299, Blast_Score=84, Evalue=8e-17, Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=30.3664921465969, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=27.4590163934426, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI31542939, Length=257, Percent_Identity=30.3501945525292, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=31.7460317460317, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4758504, Length=233, Percent_Identity=29.6137339055794, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI22507405, Length=211, Percent_Identity=29.8578199052133, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4504503, Length=209, Percent_Identity=27.7511961722488, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=28.0155642023346, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI119392083, Length=191, Percent_Identity=29.8429319371728, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI142976729, Length=238, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4504505, Length=202, Percent_Identity=28.7128712871287, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI166795268, Length=202, Percent_Identity=29.2079207920792, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI186928839, Length=202, Percent_Identity=30.1980198019802, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI4503301, Length=198, Percent_Identity=29.2929292929293, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=25.1908396946565, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI150247226, Length=186, Percent_Identity=30.6451612903226, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI4503817, Length=248, Percent_Identity=25, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI44680136, Length=186, Percent_Identity=29.5698924731183, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI44680133, Length=186, Percent_Identity=29.5698924731183, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI17738292, Length=186, Percent_Identity=29.5698924731183, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI19743808, Length=186, Percent_Identity=29.5698924731183, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI83715985, Length=227, Percent_Identity=29.5154185022026, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1786812, Length=246, Percent_Identity=56.0975609756098, Blast_Score=260, Evalue=8e-71, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=34.2741935483871, Blast_Score=131, Evalue=4e-32, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=30.1960784313725, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=27.027027027027, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=27.906976744186, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=30.3501945525292, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=25.9842519685039, Blast_Score=86, Evalue=4e-18, Organism=Escherichia coli, GI1789378, Length=267, Percent_Identity=29.5880149812734, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=29.9595141700405, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1787820, Length=176, Percent_Identity=30.6818181818182, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=30.3149606299213, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=26.0536398467433, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=27.4590163934426, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=31.0077519379845, Blast_Score=117, Evalue=8e-27, Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=33.7121212121212, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=35.5555555555556, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=33.7121212121212, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=34.7169811320755, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=32.5490196078431, Blast_Score=106, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=31.25, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=34.0909090909091, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=33.2075471698113, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=29.0196078431373, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=29.9625468164794, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=31.203007518797, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=27.6264591439689, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=32.4528301886792, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=32.4626865671642, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=31.0861423220974, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=31.5789473684211, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=30.9236947791165, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=30.7116104868914, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=31.1111111111111, Blast_Score=91, Evalue=9e-19, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=30.1204819277108, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=31.9852941176471, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17560332, Length=277, Percent_Identity=31.0469314079422, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=30.188679245283, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=28.740157480315, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=30.0751879699248, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17557780, Length=198, Percent_Identity=29.2929292929293, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI212645366, Length=246, Percent_Identity=30.4878048780488, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17508651, Length=161, Percent_Identity=29.1925465838509, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=30.2083333333333, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17538182, Length=218, Percent_Identity=31.1926605504587, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=27.6041666666667, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=28.968253968254, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=26.1780104712042, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193210355, Length=201, Percent_Identity=28.3582089552239, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193207185, Length=126, Percent_Identity=38.8888888888889, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI193203115, Length=202, Percent_Identity=26.7326732673267, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193203117, Length=193, Percent_Identity=26.9430051813472, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17561272, Length=197, Percent_Identity=26.3959390862944, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=259, Percent_Identity=29.7297297297297, Blast_Score=87, Evalue=3e-18, Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=25.1282051282051, Blast_Score=68, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=265, Percent_Identity=26.0377358490566, Blast_Score=66, Evalue=6e-12, Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=29.0816326530612, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6320089, Length=199, Percent_Identity=23.6180904522613, Blast_Score=63, Evalue=5e-11, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=30.952380952381, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=29.6875, Blast_Score=108, Evalue=5e-24, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=33.596837944664, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=34.9019607843137, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=31.8897637795276, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=31.7269076305221, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI24644337, Length=257, Percent_Identity=34.2412451361868, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI18859837, Length=196, Percent_Identity=30.1020408163265, Blast_Score=81, Evalue=8e-16, Organism=Drosophila melanogaster, GI17737361, Length=230, Percent_Identity=29.1304347826087, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI281364892, Length=193, Percent_Identity=27.4611398963731, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665243, Length=195, Percent_Identity=28.7179487179487, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI221331218, Length=195, Percent_Identity=28.7179487179487, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI28574402, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24584744, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI221331216, Length=196, Percent_Identity=28.0612244897959, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24665247, Length=196, Percent_Identity=28.0612244897959, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21356301, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI161076933, Length=188, Percent_Identity=27.1276595744681, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24584748, Length=188, Percent_Identity=27.1276595744681, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR003560 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.28 [H]
Molecular weight: Translated: 27147; Mature: 27147
Theoretical pI: Translated: 6.78; Mature: 6.78
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVEAKSYPASWRFAGKRVIVTGAAQGIGRRVAEHFLAEGATVIGLDRQAGEADAPFRLIR CCCCCCCCCCEEECCCEEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEE LDITDAAEVRAVSDGLKAEGKPLDILVNVAGVLKLGNSDRLSAEDWKTCMDVNASGPFHL EECCCCHHHHHHHCCCCCCCCCEEEEEEEEEHEEECCCCCCCHHHHHHHHCCCCCCCHHH LSQWVPVFRDQRHGAIVNVASNAAHVPRLNMAAYCASKAALASFSHCVALELAPYGVRCN HHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEECCCCEEEE VVSPGSTRTAMLGAMLNDPSGEAQLVRGLPEQFKLGIPLGKIAIPDDIANVILFLASDQA EECCCCCHHHHHHHHHCCCCCHHHHHHCCCHHHEECCCCCCEECCHHHHHEEEEEECCCC GHVTMQDIVVDGGATLGA CCEEEEEEEEECCCCCCC >Mature Secondary Structure MVEAKSYPASWRFAGKRVIVTGAAQGIGRRVAEHFLAEGATVIGLDRQAGEADAPFRLIR CCCCCCCCCCEEECCCEEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEE LDITDAAEVRAVSDGLKAEGKPLDILVNVAGVLKLGNSDRLSAEDWKTCMDVNASGPFHL EECCCCHHHHHHHCCCCCCCCCEEEEEEEEEHEEECCCCCCCHHHHHHHHCCCCCCCHHH LSQWVPVFRDQRHGAIVNVASNAAHVPRLNMAAYCASKAALASFSHCVALELAPYGVRCN HHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEECCCCEEEE VVSPGSTRTAMLGAMLNDPSGEAQLVRGLPEQFKLGIPLGKIAIPDDIANVILFLASDQA EECCCCCHHHHHHHHHCCCCCHHHHHHCCCHHHEECCCCCCEECCHHHHHEEEEEECCCC GHVTMQDIVVDGGATLGA CCEEEEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2521622; 2521621; 9278503 [H]