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The map label for this gene is cmpR [H]

Identifier: 222527423

GI number: 222527423

Start: 5222200

End: 5223096

Strand: Direct

Name: cmpR [H]

Synonym: Chy400_4214

Alternate gene names: 222527423

Gene position: 5222200-5223096 (Clockwise)

Preceding gene: 222527419

Following gene: 222527428

Centisome position: 99.11

GC content: 58.42

Gene sequence:

>897_bases
ATGCTCGATCTCTACAAACTCGATATCTTTACCCGCGTTGTAGCCGCCGGGAGTCTCAGCAAAGCGGCTGAACAGCTACA
CATGACGCAATCAGGGGTGAGCCAGCATATCCGTGCGCTCGAAGATTCGTTAGGCACTGAACTCTTCGTGCGTGGCCGGC
GTGGTGTTGAGCTGACGCCAGCCGGTCAACGTCTGCTGGCGTATTGTGAGGGCATTTTTCGCCTGGTCGCCGAGGCCGAA
CTGGCAGTGACTGATGTTGCCGGTCTGCGAGATGGACAGTTGACGATTGGGGTGACACCCGGTGTAAGTGCCTATCTCTT
GCCTGAATGGGTGCAGATGTTTCGCCAGCGCTATCCCAACCTCGCCGTGAGCGCCCAAACCGGCACGACGCCATCTATCG
TGAATGAATTACGGAACGGCAGCCTCGATCTGGGTGCAATCGAGGGCGAACTCGATAGCGCGGAACGTGATTTGCAGCAA
CAGGCGCTGCGCGAATTCGATCAATACGTCGTCGTTGGTCGCCGCCATCCGTGGTGGGGGCGCAGTGAGGTTCATTTGCA
AGAGCTGGCCGGTCAGCCGATGGTGATGCGCCAATCGAGCAGTCAAACGCGCGTCTGGCTCGATCATGCCCTGCGCGAGC
AATCATTAACGCCCCGCATCATCGCCGAACTCGACAATCTGGAGTCGATTAAGCGCATGGTGATGATCGGAACCGGCCTG
ACAATCCTGCCGCTCTACGCTGTAACTGCCGAACAAGAAGTTGGTGCCCTGCATCCCATCCCTATCGCGGGCCGGCCACT
ACGCCGCACACTACGCCTGCTATGGCGGGCAACCCGCCCCCTATCACCGGTGGCGTATGCCTTCCGACAATTACTCATTG
CGCATTACGGTCATTGA

Upstream 100 bases:

>100_bases
CAAGAATCATTGCATCCAGGAATAGATGCATTTCTCTGAATGCACAGGTTTGATCATTTGGTATCGACAGGTTGTCTAAA
CAGCATAACCAGGAGCAACG

Downstream 100 bases:

>100_bases
TTTTTGCCCGCAGACGTTGTTGCATCTGAACAATTAAACGTTCTTCCAAAGCAGGTGGTAATGGCAGTGGTTCATCTTCA
AGGTGATGGAGCAGGCTAAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MLDLYKLDIFTRVVAAGSLSKAAEQLHMTQSGVSQHIRALEDSLGTELFVRGRRGVELTPAGQRLLAYCEGIFRLVAEAE
LAVTDVAGLRDGQLTIGVTPGVSAYLLPEWVQMFRQRYPNLAVSAQTGTTPSIVNELRNGSLDLGAIEGELDSAERDLQQ
QALREFDQYVVVGRRHPWWGRSEVHLQELAGQPMVMRQSSSQTRVWLDHALREQSLTPRIIAELDNLESIKRMVMIGTGL
TILPLYAVTAEQEVGALHPIPIAGRPLRRTLRLLWRATRPLSPVAYAFRQLLIAHYGH

Sequences:

>Translated_298_residues
MLDLYKLDIFTRVVAAGSLSKAAEQLHMTQSGVSQHIRALEDSLGTELFVRGRRGVELTPAGQRLLAYCEGIFRLVAEAE
LAVTDVAGLRDGQLTIGVTPGVSAYLLPEWVQMFRQRYPNLAVSAQTGTTPSIVNELRNGSLDLGAIEGELDSAERDLQQ
QALREFDQYVVVGRRHPWWGRSEVHLQELAGQPMVMRQSSSQTRVWLDHALREQSLTPRIIAELDNLESIKRMVMIGTGL
TILPLYAVTAEQEVGALHPIPIAGRPLRRTLRLLWRATRPLSPVAYAFRQLLIAHYGH
>Mature_298_residues
MLDLYKLDIFTRVVAAGSLSKAAEQLHMTQSGVSQHIRALEDSLGTELFVRGRRGVELTPAGQRLLAYCEGIFRLVAEAE
LAVTDVAGLRDGQLTIGVTPGVSAYLLPEWVQMFRQRYPNLAVSAQTGTTPSIVNELRNGSLDLGAIEGELDSAERDLQQ
QALREFDQYVVVGRRHPWWGRSEVHLQELAGQPMVMRQSSSQTRVWLDHALREQSLTPRIIAELDNLESIKRMVMIGTGL
TILPLYAVTAEQEVGALHPIPIAGRPLRRTLRLLWRATRPLSPVAYAFRQLLIAHYGH

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=282, Percent_Identity=30.8510638297872, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788297, Length=244, Percent_Identity=29.0983606557377, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787530, Length=236, Percent_Identity=31.3559322033898, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790399, Length=307, Percent_Identity=27.3615635179153, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI145693105, Length=293, Percent_Identity=28.6689419795222, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788481, Length=291, Percent_Identity=26.8041237113402, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788887, Length=283, Percent_Identity=28.9752650176678, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788296, Length=228, Percent_Identity=31.5789473684211, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI87082132, Length=296, Percent_Identity=27.3648648648649, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787806, Length=298, Percent_Identity=27.8523489932886, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=27.6450511945392, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788748, Length=296, Percent_Identity=27.3648648648649, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789506, Length=243, Percent_Identity=27.5720164609054, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789204, Length=252, Percent_Identity=28.1746031746032, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787601, Length=244, Percent_Identity=25.8196721311475, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1790262, Length=256, Percent_Identity=24.609375, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786401, Length=131, Percent_Identity=36.6412213740458, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081904, Length=142, Percent_Identity=28.8732394366197, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI48994962, Length=146, Percent_Identity=32.1917808219178, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790208, Length=248, Percent_Identity=24.1935483870968, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788626, Length=268, Percent_Identity=27.6119402985075, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789639, Length=152, Percent_Identity=28.9473684210526, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33232; Mature: 33232

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLYKLDIFTRVVAAGSLSKAAEQLHMTQSGVSQHIRALEDSLGTELFVRGRRGVELTP
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEECC
AGQRLLAYCEGIFRLVAEAELAVTDVAGLRDGQLTIGVTPGVSAYLLPEWVQMFRQRYPN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
LAVSAQTGTTPSIVNELRNGSLDLGAIEGELDSAERDLQQQALREFDQYVVVGRRHPWWG
EEEECCCCCCHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCC
RSEVHLQELAGQPMVMRQSSSQTRVWLDHALREQSLTPRIIAELDNLESIKRMVMIGTGL
CCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCH
TILPLYAVTAEQEVGALHPIPIAGRPLRRTLRLLWRATRPLSPVAYAFRQLLIAHYGH
HHHHHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDLYKLDIFTRVVAAGSLSKAAEQLHMTQSGVSQHIRALEDSLGTELFVRGRRGVELTP
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEECC
AGQRLLAYCEGIFRLVAEAELAVTDVAGLRDGQLTIGVTPGVSAYLLPEWVQMFRQRYPN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
LAVSAQTGTTPSIVNELRNGSLDLGAIEGELDSAERDLQQQALREFDQYVVVGRRHPWWG
EEEECCCCCCHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCC
RSEVHLQELAGQPMVMRQSSSQTRVWLDHALREQSLTPRIIAELDNLESIKRMVMIGTGL
CCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCH
TILPLYAVTAEQEVGALHPIPIAGRPLRRTLRLLWRATRPLSPVAYAFRQLLIAHYGH
HHHHHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]