Click here to switch to the map view.

The map label for this gene is yfhA [H]

Identifier: 222527351

GI number: 222527351

Start: 5126095

End: 5127165

Strand: Direct

Name: yfhA [H]

Synonym: Chy400_4140

Alternate gene names: 222527351

Gene position: 5126095-5127165 (Clockwise)

Preceding gene: 222527350

Following gene: 222527352

Centisome position: 97.29

GC content: 58.45

Gene sequence:

>1071_bases
ATGAGTGTTGAGGTTCCATCTTCCCGTGGTCAGCAGTCACCGTGGCTAACCCTGCGCACCCGTGGTCTTTCTTTTCGCAT
TGACCGACGTGTGCCGCCGGTACTGACTCTGGCACTGCTGGCAACGATCACAGCAATGGTGATCAACATTGGGGTCGGTG
CATACCCTATCCCACCGCTCGATGTGATACGGACTGTGCTCGGCCTACCGACCGGCAATGAAGACTATTCCTTCATCGTG
AACGTTTTACGTCTACCGCGTATGCTCGTCGCTGCGCTAGTCGGCATGGCACTTGGGGTGTCTGGAGCGATTATCCAGGG
CTTGACCCGCAATCCACTGGCCGATCCCGGCATCCTTGGCATCAGCGCCGGCGCCAGCCTCAGCGCCGTGACCCTTATCG
TGGTCGTACGCAACGTACCATCCGGCGTGATTCCTATTGCTGCTTTCGGCGGTGCTGTTACGGTCGCCACATTGATCTAT
CTTCTGGCCTGGCGAGGCGGCGATTCTCCCATTCGATTGGTCCTGGTCGGCATTGGATTGGGGGCAATCTGTAGCGCAGC
CACAACCTTGATGATCACCTTTGGCGATATTTGGGATGTACAACGGGCGCTGGTCTGGATCACGGGCAGTGTCTACGGAC
GCTCGTGGGAAGAGTTCTGGCCCCTCTTGCCGTGGATCGTTATCTTTGTACCACTGGCCTTCTTTCTGGCTCGCGATCTC
AACGCCCTCAATCTGGGTGAAGAAGTCGCGCAGGGATTAGGCATCCCAGTGGCCTGGCGGCGCGGCCTGTTACTGCTCAC
AGCGGTCGCCCTGGCAGCAGCAACAGTTGCTGCTGCGGGTACGATTGGCTTTGTGGGCTTAATGGCGCCACATATCGGGC
GGAGACTGGTTGGTCCTGATCATAGCGGCTTGTTGCCAACCGCCGGCATCATCGGCGCACTCCTGGTCGTCCTGGCCGAT
CTGGTGGGGCGCACGCTGTTTTCACCCATCGAACTACCTGCCGGATTGGTTACCGCTGCCATTGGCGCACCTTTCTTTAT
CGGATTGCTGTGGCGACAGCAAAAGCGATGA

Upstream 100 bases:

>100_bases
GCCCCCACCGCACTGCCGAAGATCGGCAGGCACGACTCCTCGCTTACATGGCGCAGAAGTACACCCAGCAACAGCAGCTC
GTTCAGGAAGAGGTAACGGC

Downstream 100 bases:

>100_bases
ACATGTTACGTCTACACGCATCGGGATCATCTGAGAAAGAAATGATCTATGTTGCATACTGAGAAACTTACCCTGGCCTA
TGATCAAACCATCATCATCC

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSVEVPSSRGQQSPWLTLRTRGLSFRIDRRVPPVLTLALLATITAMVINIGVGAYPIPPLDVIRTVLGLPTGNEDYSFIV
NVLRLPRMLVAALVGMALGVSGAIIQGLTRNPLADPGILGISAGASLSAVTLIVVVRNVPSGVIPIAAFGGAVTVATLIY
LLAWRGGDSPIRLVLVGIGLGAICSAATTLMITFGDIWDVQRALVWITGSVYGRSWEEFWPLLPWIVIFVPLAFFLARDL
NALNLGEEVAQGLGIPVAWRRGLLLLTAVALAAATVAAAGTIGFVGLMAPHIGRRLVGPDHSGLLPTAGIIGALLVVLAD
LVGRTLFSPIELPAGLVTAAIGAPFFIGLLWRQQKR

Sequences:

>Translated_356_residues
MSVEVPSSRGQQSPWLTLRTRGLSFRIDRRVPPVLTLALLATITAMVINIGVGAYPIPPLDVIRTVLGLPTGNEDYSFIV
NVLRLPRMLVAALVGMALGVSGAIIQGLTRNPLADPGILGISAGASLSAVTLIVVVRNVPSGVIPIAAFGGAVTVATLIY
LLAWRGGDSPIRLVLVGIGLGAICSAATTLMITFGDIWDVQRALVWITGSVYGRSWEEFWPLLPWIVIFVPLAFFLARDL
NALNLGEEVAQGLGIPVAWRRGLLLLTAVALAAATVAAAGTIGFVGLMAPHIGRRLVGPDHSGLLPTAGIIGALLVVLAD
LVGRTLFSPIELPAGLVTAAIGAPFFIGLLWRQQKR
>Mature_355_residues
SVEVPSSRGQQSPWLTLRTRGLSFRIDRRVPPVLTLALLATITAMVINIGVGAYPIPPLDVIRTVLGLPTGNEDYSFIVN
VLRLPRMLVAALVGMALGVSGAIIQGLTRNPLADPGILGISAGASLSAVTLIVVVRNVPSGVIPIAAFGGAVTVATLIYL
LAWRGGDSPIRLVLVGIGLGAICSAATTLMITFGDIWDVQRALVWITGSVYGRSWEEFWPLLPWIVIFVPLAFFLARDLN
ALNLGEEVAQGLGIPVAWRRGLLLLTAVALAAATVAAAGTIGFVGLMAPHIGRRLVGPDHSGLLPTAGIIGALLVVLADL
VGRTLFSPIELPAGLVTAAIGAPFFIGLLWRQQKR

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=308, Percent_Identity=39.6103896103896, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1786804, Length=330, Percent_Identity=35.7575757575758, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788004, Length=275, Percent_Identity=39.6363636363636, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1786347, Length=274, Percent_Identity=37.2262773722628, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786805, Length=308, Percent_Identity=36.6883116883117, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790741, Length=308, Percent_Identity=36.3636363636364, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37336; Mature: 37205

Theoretical pI: Translated: 11.05; Mature: 11.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEVPSSRGQQSPWLTLRTRGLSFRIDRRVPPVLTLALLATITAMVINIGVGAYPIPPL
CCCCCCCCCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHH
DVIRTVLGLPTGNEDYSFIVNVLRLPRMLVAALVGMALGVSGAIIQGLTRNPLADPGILG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEE
ISAGASLSAVTLIVVVRNVPSGVIPIAAFGGAVTVATLIYLLAWRGGDSPIRLVLVGIGL
ECCCCCHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHCH
GAICSAATTLMITFGDIWDVQRALVWITGSVYGRSWEEFWPLLPWIVIFVPLAFFLARDL
HHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
NALNLGEEVAQGLGIPVAWRRGLLLLTAVALAAATVAAAGTIGFVGLMAPHIGRRLVGPD
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
HSGLLPTAGIIGALLVVLADLVGRTLFSPIELPAGLVTAAIGAPFFIGLLWRQQKR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVEVPSSRGQQSPWLTLRTRGLSFRIDRRVPPVLTLALLATITAMVINIGVGAYPIPPL
CCCCCCCCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHH
DVIRTVLGLPTGNEDYSFIVNVLRLPRMLVAALVGMALGVSGAIIQGLTRNPLADPGILG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEE
ISAGASLSAVTLIVVVRNVPSGVIPIAAFGGAVTVATLIYLLAWRGGDSPIRLVLVGIGL
ECCCCCHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHCH
GAICSAATTLMITFGDIWDVQRALVWITGSVYGRSWEEFWPLLPWIVIFVPLAFFLARDL
HHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
NALNLGEEVAQGLGIPVAWRRGLLLLTAVALAAATVAAAGTIGFVGLMAPHIGRRLVGPD
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
HSGLLPTAGIIGALLVVLADLVGRTLFSPIELPAGLVTAAIGAPFFIGLLWRQQKR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]