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The map label for this gene is acoB [H]

Identifier: 222527176

GI number: 222527176

Start: 4906889

End: 4907923

Strand: Reverse

Name: acoB [H]

Synonym: Chy400_3958

Alternate gene names: 222527176

Gene position: 4907923-4906889 (Counterclockwise)

Preceding gene: 222527177

Following gene: 222527175

Centisome position: 93.15

GC content: 56.62

Gene sequence:

>1035_bases
ATGACTGCAATGGTTGAAGAGGCAGTACGTACTCTGAGCTATCGTGAGGCGATCAATGAGGCATTGCGTCTTGAGATGCG
GCGCGATCCAACGGTTATCTTAATGGGTGAAGATGTCACCGGAGCATCCCATAGTGAAGACGAGAGCCATCTTGATGCCT
GGGGTGGGGTGTTGGGGGTGACGAAGGGTTTAGTACACGAATTTGGCCGTCAGCGTGTGCGTGATACGCCAATTACCGAG
TCGGGATTTGTTGGAGCCGGTGTCGGCGCAGCGGCAACCGGTCTACGACCGGTGGTTGAGCTGATGTTCATCGGCTTTAT
GGGGGTATGCCTCGACCAGATCGTCAATCAGGCCGCCAAGATGCGCTACATGTTCGGTGGCAAGGCGCGCATTCCACTCG
TCATTCGGACGATGATCGGGGCCGGTTTTCGGGCAGCAGCCCAGCACTCCGACTCGATCTACTCGACGTTTGTTCATTTC
CCCGGCCTGAAGGTGGTTGCGCCGGCGACTCCGGCTGATGCGAAGGGATTGCTGGCAGCGGCTATTCGTGACGATGACCC
GGTTATCTTCTGTGAGCACAAACTGCTTTACGATATGAAAGGGCCGGTTCCCGAAGGTGAATATGTTATTCCGCTTGGGC
AGGCTGATGTGAAGCGCGAAGGTGGTGATGTCACGATTGTAGCCATCTCTCGTATGGTATTGCACGCTTTAGAGGCGGCC
GAGCGATTAGCGCAACAAGGTATCAGCGCTGAAGTCATTGATCTTCGCACCTTATCACCACTCGATGAGACGACGGTACT
GGAGTCGGTGCGGAAGACCGGCCGTCTGGTTGTGGTTGATGAAGATAATCCACGGTGCAGTGTGGCGGGCGATATTGCCA
CCCTGGCGGCGACACAGGCGCTGGAATTTTTGAATGCGCCGGTCAAGCTGGTCACACCGCCGCATACCCCGGTACCGTTT
AGCCCGACACTGGAAGATGCCTATGTGCCTTCGCCTGAGCGGATTGTGGCAGCGGCGCGGGCGACATTTGGCTGA

Upstream 100 bases:

>100_bases
CTGCCGTCGCAGTACGACGCTAGATGCGAATAGAGATAGTGAGCTGTAGGGAAGGGGTAGCTTTCCTTCGGCACAGACAA
CTCAACGATGAGGTGATACT

Downstream 100 bases:

>100_bases
TTCTGGGGGCGCTTGTTGCAGGAGAGATCATGCCTACCGAGGTTGTGATGCCAAAGTGGGGCTTGAGCATGCAAGAGGGA
AAGATCAACCTCTGGCTCAA

Product: transketolase central subunit

Products: NA

Alternate protein names: Acetoin:DCPIP oxidoreductase-beta; Ao:DCPIP OR; TPP-dependent acetoin dehydrogenase E1 subunit beta [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTAMVEEAVRTLSYREAINEALRLEMRRDPTVILMGEDVTGASHSEDESHLDAWGGVLGVTKGLVHEFGRQRVRDTPITE
SGFVGAGVGAAATGLRPVVELMFIGFMGVCLDQIVNQAAKMRYMFGGKARIPLVIRTMIGAGFRAAAQHSDSIYSTFVHF
PGLKVVAPATPADAKGLLAAAIRDDDPVIFCEHKLLYDMKGPVPEGEYVIPLGQADVKREGGDVTIVAISRMVLHALEAA
ERLAQQGISAEVIDLRTLSPLDETTVLESVRKTGRLVVVDEDNPRCSVAGDIATLAATQALEFLNAPVKLVTPPHTPVPF
SPTLEDAYVPSPERIVAAARATFG

Sequences:

>Translated_344_residues
MTAMVEEAVRTLSYREAINEALRLEMRRDPTVILMGEDVTGASHSEDESHLDAWGGVLGVTKGLVHEFGRQRVRDTPITE
SGFVGAGVGAAATGLRPVVELMFIGFMGVCLDQIVNQAAKMRYMFGGKARIPLVIRTMIGAGFRAAAQHSDSIYSTFVHF
PGLKVVAPATPADAKGLLAAAIRDDDPVIFCEHKLLYDMKGPVPEGEYVIPLGQADVKREGGDVTIVAISRMVLHALEAA
ERLAQQGISAEVIDLRTLSPLDETTVLESVRKTGRLVVVDEDNPRCSVAGDIATLAATQALEFLNAPVKLVTPPHTPVPF
SPTLEDAYVPSPERIVAAARATFG
>Mature_343_residues
TAMVEEAVRTLSYREAINEALRLEMRRDPTVILMGEDVTGASHSEDESHLDAWGGVLGVTKGLVHEFGRQRVRDTPITES
GFVGAGVGAAATGLRPVVELMFIGFMGVCLDQIVNQAAKMRYMFGGKARIPLVIRTMIGAGFRAAAQHSDSIYSTFVHFP
GLKVVAPATPADAKGLLAAAIRDDDPVIFCEHKLLYDMKGPVPEGEYVIPLGQADVKREGGDVTIVAISRMVLHALEAAE
RLAQQGISAEVIDLRTLSPLDETTVLESVRKTGRLVVVDEDNPRCSVAGDIATLAATQALEFLNAPVKLVTPPHTPVPFS
PTLEDAYVPSPERIVAAARATFG

Specific function: Catalyzes the 2,6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde [H]

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI156564403, Length=342, Percent_Identity=39.1812865497076, Blast_Score=245, Evalue=5e-65,
Organism=Homo sapiens, GI291084858, Length=342, Percent_Identity=37.4269005847953, Blast_Score=228, Evalue=7e-60,
Organism=Homo sapiens, GI4557353, Length=335, Percent_Identity=37.910447761194, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI34101272, Length=335, Percent_Identity=37.910447761194, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17538422, Length=342, Percent_Identity=42.1052631578947, Blast_Score=260, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI17506935, Length=335, Percent_Identity=39.7014925373134, Blast_Score=199, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6319698, Length=339, Percent_Identity=40.4129793510324, Blast_Score=246, Evalue=5e-66,
Organism=Drosophila melanogaster, GI21358145, Length=342, Percent_Identity=40.9356725146199, Blast_Score=244, Evalue=7e-65,
Organism=Drosophila melanogaster, GI24650940, Length=342, Percent_Identity=40.9356725146199, Blast_Score=244, Evalue=7e-65,
Organism=Drosophila melanogaster, GI160714832, Length=333, Percent_Identity=36.036036036036, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI160714828, Length=333, Percent_Identity=36.036036036036, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24650943, Length=105, Percent_Identity=40, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24650945, Length=105, Percent_Identity=40, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: NA

Molecular weight: Translated: 36865; Mature: 36734

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAMVEEAVRTLSYREAINEALRLEMRRDPTVILMGEDVTGASHSEDESHLDAWGGVLGV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
TKGLVHEFGRQRVRDTPITESGFVGAGVGAAATGLRPVVELMFIGFMGVCLDQIVNQAAK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRYMFGGKARIPLVIRTMIGAGFRAAAQHSDSIYSTFVHFPGLKVVAPATPADAKGLLAA
HHHHCCCCCCCHHHHHHHHCCCHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCHHEEE
AIRDDDPVIFCEHKLLYDMKGPVPEGEYVIPLGQADVKREGGDVTIVAISRMVLHALEAA
EECCCCCEEEECCEEEECCCCCCCCCCEEEECCCCHHHCCCCCEEEHHHHHHHHHHHHHH
ERLAQQGISAEVIDLRTLSPLDETTVLESVRKTGRLVVVDEDNPRCSVAGDIATLAATQA
HHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCEEECHHHHHHHHHHH
LEFLNAPVKLVTPPHTPVPFSPTLEDAYVPSPERIVAAARATFG
HHHHCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TAMVEEAVRTLSYREAINEALRLEMRRDPTVILMGEDVTGASHSEDESHLDAWGGVLGV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
TKGLVHEFGRQRVRDTPITESGFVGAGVGAAATGLRPVVELMFIGFMGVCLDQIVNQAAK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRYMFGGKARIPLVIRTMIGAGFRAAAQHSDSIYSTFVHFPGLKVVAPATPADAKGLLAA
HHHHCCCCCCCHHHHHHHHCCCHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCHHEEE
AIRDDDPVIFCEHKLLYDMKGPVPEGEYVIPLGQADVKREGGDVTIVAISRMVLHALEAA
EECCCCCEEEECCEEEECCCCCCCCCCEEEECCCCHHHCCCCCEEEHHHHHHHHHHHHHH
ERLAQQGISAEVIDLRTLSPLDETTVLESVRKTGRLVVVDEDNPRCSVAGDIATLAATQA
HHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCEEECHHHHHHHHHHH
LEFLNAPVKLVTPPHTPVPFSPTLEDAYVPSPERIVAAARATFG
HHHHCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10368162; 8969503; 9384377 [H]