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The map label for this gene is csd [H]

Identifier: 222526974

GI number: 222526974

Start: 4674057

End: 4675295

Strand: Direct

Name: csd [H]

Synonym: Chy400_3752

Alternate gene names: 222526974

Gene position: 4674057-4675295 (Clockwise)

Preceding gene: 222526973

Following gene: 222526975

Centisome position: 88.71

GC content: 58.43

Gene sequence:

>1239_bases
ATGGCTATCCTGTCTCAGTTCGATGTGCTTGCACTGCGACGAGAGTTTCCGATCTTGCAACAGCATGTTCACGGCAAGCC
ACTGGCCTTTCTCGACAGTGCCGCATCGTCACAAAAACCACGCCGGGTGATTGAGACGCTGGAAGATTATTACCGGCGCT
ACAATGCCAACGTTCATCGCGGTGTCTACCGCTTGAGCGAAGAGGCAACCTTTGCCTACGAGCGAGCACGGGGAAAGCTG
GCACGCTTTATCAATGCTGCCAGTCAACGCGAGATCATTTTTGTTCGTAATACCACCGAAGCGATTAACCTGGTTGCTTA
TGCCTGGGGTGGGGCAAATATTCGCGCTGGTGATCGCATTTTGCTGACTATGATGGAGCACCACTCGAATATTGTGCCCT
GGCAGTTGCTGGCGCAACGTACCGGTGCCGAGCTGATCTATCTGCCCTTCGATGGGCAGGGACGACTGGTACTTGATGAT
CTCGACCGTCTGCTCGACGAACGGGTAAAGCTGGTTGCCTTTACGCACCAATCGAACGTCTTGGGCACGATCAACCCGGT
GGCACCAATTGTCGCCCGGGCGCGAGCAGTCGGAGCACGGGTCTTGCTCGACGCTGCCCAGAGTGTGCCGCATATGCCGG
TTGACGTACAGGCGTTGGGTATTGATTTTCTGGCCTTTAGCGGCCACAAGATGTGCGGCCCAACCGGGATTGGCGTGCTG
TGGGGCCGGCGTGAGGTGTTGCAGGCGATGCCGCCATTTCTGGGTGGTGGCTCAATGATCGACCTGGTCGAGCTTGATCA
CAGTACCTTCGCCGCGATACCGGCACGGTTTGAGGCAGGAACACCGGCAATCGGCGAAGCAATCGCTCTCGGCGAAGCAG
CCGACTACCTGCAAGAGGTGGGATTGGCGACCATTCATCAGCACGAACAGGAACTGACCGCGTATGCACTTGAACGGCTG
GCCGCCGTTCCCGGCATAACGATCTATGGGCCGCCGGCCGGGCCAGATCGCGGCGGTGCCATCAGCTTCAGCCTTGAAGG
CGTCCATCCGCACGACGTGGCGGCGGTTCTGGATCAGGAAGGGGTTGCAGTACGTGCCGGCCATCACTGTACCCAGCCCC
TGCATCGGGTATTAGGGGTACCGGCAACCACGCGGGCCAGCTTCTACCTGTACAACTTGCCCGAAGAGATTGATCGGCTG
GTTGCCGGGTTGCACAAGGCACGACAGCTCTTTGCCTGA

Upstream 100 bases:

>100_bases
GGTTAGCCTGCGGCAAGCCCCCGGATACGGTCGTCGGAGAGCGCCTTGCCGTATAGACTGTCGCCGACAATCCTGGCGGT
GACAGATGAGGTCATAGAAT

Downstream 100 bases:

>100_bases
TAGAGGCAGGAAACGACCATGGATGACATTTATCGCGAACAAATTCTCGAACATGCCCGTCATCCGCGCAACTTCGGTCA
TCTACCGGCACCGACGGTTA

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MAILSQFDVLALRREFPILQQHVHGKPLAFLDSAASSQKPRRVIETLEDYYRRYNANVHRGVYRLSEEATFAYERARGKL
ARFINAASQREIIFVRNTTEAINLVAYAWGGANIRAGDRILLTMMEHHSNIVPWQLLAQRTGAELIYLPFDGQGRLVLDD
LDRLLDERVKLVAFTHQSNVLGTINPVAPIVARARAVGARVLLDAAQSVPHMPVDVQALGIDFLAFSGHKMCGPTGIGVL
WGRREVLQAMPPFLGGGSMIDLVELDHSTFAAIPARFEAGTPAIGEAIALGEAADYLQEVGLATIHQHEQELTAYALERL
AAVPGITIYGPPAGPDRGGAISFSLEGVHPHDVAAVLDQEGVAVRAGHHCTQPLHRVLGVPATTRASFYLYNLPEEIDRL
VAGLHKARQLFA

Sequences:

>Translated_412_residues
MAILSQFDVLALRREFPILQQHVHGKPLAFLDSAASSQKPRRVIETLEDYYRRYNANVHRGVYRLSEEATFAYERARGKL
ARFINAASQREIIFVRNTTEAINLVAYAWGGANIRAGDRILLTMMEHHSNIVPWQLLAQRTGAELIYLPFDGQGRLVLDD
LDRLLDERVKLVAFTHQSNVLGTINPVAPIVARARAVGARVLLDAAQSVPHMPVDVQALGIDFLAFSGHKMCGPTGIGVL
WGRREVLQAMPPFLGGGSMIDLVELDHSTFAAIPARFEAGTPAIGEAIALGEAADYLQEVGLATIHQHEQELTAYALERL
AAVPGITIYGPPAGPDRGGAISFSLEGVHPHDVAAVLDQEGVAVRAGHHCTQPLHRVLGVPATTRASFYLYNLPEEIDRL
VAGLHKARQLFA
>Mature_411_residues
AILSQFDVLALRREFPILQQHVHGKPLAFLDSAASSQKPRRVIETLEDYYRRYNANVHRGVYRLSEEATFAYERARGKLA
RFINAASQREIIFVRNTTEAINLVAYAWGGANIRAGDRILLTMMEHHSNIVPWQLLAQRTGAELIYLPFDGQGRLVLDDL
DRLLDERVKLVAFTHQSNVLGTINPVAPIVARARAVGARVLLDAAQSVPHMPVDVQALGIDFLAFSGHKMCGPTGIGVLW
GRREVLQAMPPFLGGGSMIDLVELDHSTFAAIPARFEAGTPAIGEAIALGEAADYLQEVGLATIHQHEQELTAYALERLA
AVPGITIYGPPAGPDRGGAISFSLEGVHPHDVAAVLDQEGVAVRAGHHCTQPLHRVLGVPATTRASFYLYNLPEEIDRLV
AGLHKARQLFA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=356, Percent_Identity=26.685393258427, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI156713448, Length=290, Percent_Identity=26.8965517241379, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787970, Length=406, Percent_Identity=51.4778325123153, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1789175, Length=408, Percent_Identity=38.2352941176471, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI48994898, Length=220, Percent_Identity=31.8181818181818, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI193211090, Length=383, Percent_Identity=24.5430809399478, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI25143064, Length=265, Percent_Identity=26.7924528301887, Blast_Score=98, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6319831, Length=228, Percent_Identity=30.7017543859649, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI20129463, Length=246, Percent_Identity=30.0813008130081, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45063; Mature: 44932

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILSQFDVLALRREFPILQQHVHGKPLAFLDSAASSQKPRRVIETLEDYYRRYNANVHR
CCCHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHH
GVYRLSEEATFAYERARGKLARFINAASQREIIFVRNTTEAINLVAYAWGGANIRAGDRI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHEEEEEEEECCCCCCCCCHH
LLTMMEHHSNIVPWQLLAQRTGAELIYLPFDGQGRLVLDDLDRLLDERVKLVAFTHQSNV
EEEEHHHCCCCCHHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHHHHEEEEEEEECCCC
LGTINPVAPIVARARAVGARVLLDAAQSVPHMPVDVQALGIDFLAFSGHKMCGPTGIGVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEEEECCCCCCCCCCCCHH
WGRREVLQAMPPFLGGGSMIDLVELDHSTFAAIPARFEAGTPAIGEAIALGEAADYLQEV
CCHHHHHHHCCCCCCCCCEEEEEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GLATIHQHEQELTAYALERLAAVPGITIYGPPAGPDRGGAISFSLEGVHPHDVAAVLDQE
CHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHCCC
GVAVRAGHHCTQPLHRVLGVPATTRASFYLYNLPEEIDRLVAGLHKARQLFA
CCEEECCCHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AILSQFDVLALRREFPILQQHVHGKPLAFLDSAASSQKPRRVIETLEDYYRRYNANVHR
CCHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHH
GVYRLSEEATFAYERARGKLARFINAASQREIIFVRNTTEAINLVAYAWGGANIRAGDRI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHEEEEEEEECCCCCCCCCHH
LLTMMEHHSNIVPWQLLAQRTGAELIYLPFDGQGRLVLDDLDRLLDERVKLVAFTHQSNV
EEEEHHHCCCCCHHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHHHHEEEEEEEECCCC
LGTINPVAPIVARARAVGARVLLDAAQSVPHMPVDVQALGIDFLAFSGHKMCGPTGIGVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEEEECCCCCCCCCCCCHH
WGRREVLQAMPPFLGGGSMIDLVELDHSTFAAIPARFEAGTPAIGEAIALGEAADYLQEV
CCHHHHHHHCCCCCCCCCEEEEEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GLATIHQHEQELTAYALERLAAVPGITIYGPPAGPDRGGAISFSLEGVHPHDVAAVLDQE
CHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHCCC
GVAVRAGHHCTQPLHRVLGVPATTRASFYLYNLPEEIDRLVAGLHKARQLFA
CCEEECCCHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]