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The map label for this gene is yqjC [H]

Identifier: 222526516

GI number: 222526516

Start: 4092609

End: 4093028

Strand: Direct

Name: yqjC [H]

Synonym: Chy400_3283

Alternate gene names: 222526516

Gene position: 4092609-4093028 (Clockwise)

Preceding gene: 222526514

Following gene: 222526517

Centisome position: 77.67

GC content: 52.14

Gene sequence:

>420_bases
ATGTTTACGGCAATCGATCATATCGGGTTGGTGGTAGCCGATCTCGACGCTGCCATCGATTTTTATCGCACTGCATACGA
TGTGACCGAATGGGAGCGGATTGAACTCCCTGAACGCCATGCGCTGATCGGTGTTGCTCGTTTTGGTGATGTCTTGATCG
AATTAATTGCCCCAACCAGCGATCAGGCCAGCTTTGCCCGCTTCCTGCGCGAAAAAGGGCCGGGTATGCATCATATTGCC
TATCGGGTTGATGATATTTATGCGGCGTTAGCTACATTGCAGGCGCGTGGTTTACCATTGATTGACCGTGAACCTCGCCC
TGGTATCCACGACACACTGGTTGCGTTTGTCCATCCGAAAGCCGGCGGACAGGGTGTATTGGTTGAGCTAGTGCAACATC
GTTCCCCACATCACAGGTAA

Upstream 100 bases:

>100_bases
ATTGTAGCTAACCGTGAGTAGCTGTCAATTATCTCGTAATAACTCTGTGCTATGATATGCTACATCCATCGGTATTACGG
TGGAACACAAGGAGCAAACT

Downstream 100 bases:

>100_bases
GTCAAGAAAACAGATTTGGAGCAGCATGTATGACATGGAATGACGAAGAACATCGTCGCTTGCTGGTAAGCACGAGTATC
GGGTATACGGCGTACACTGC

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MFTAIDHIGLVVADLDAAIDFYRTAYDVTEWERIELPERHALIGVARFGDVLIELIAPTSDQASFARFLREKGPGMHHIA
YRVDDIYAALATLQARGLPLIDREPRPGIHDTLVAFVHPKAGGQGVLVELVQHRSPHHR

Sequences:

>Translated_139_residues
MFTAIDHIGLVVADLDAAIDFYRTAYDVTEWERIELPERHALIGVARFGDVLIELIAPTSDQASFARFLREKGPGMHHIA
YRVDDIYAALATLQARGLPLIDREPRPGIHDTLVAFVHPKAGGQGVLVELVQHRSPHHR
>Mature_139_residues
MFTAIDHIGLVVADLDAAIDFYRTAYDVTEWERIELPERHALIGVARFGDVLIELIAPTSDQASFARFLREKGPGMHHIA
YRVDDIYAALATLQARGLPLIDREPRPGIHDTLVAFVHPKAGGQGVLVELVQHRSPHHR

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyoxalase I family [H]

Homologues:

Organism=Homo sapiens, GI188035928, Length=129, Percent_Identity=35.6589147286822, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17506387, Length=133, Percent_Identity=30.0751879699248, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR018146
- InterPro:   IPR017515 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 15522; Mature: 15522

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTAIDHIGLVVADLDAAIDFYRTAYDVTEWERIELPERHALIGVARFGDVLIELIAPTS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
DQASFARFLREKGPGMHHIAYRVDDIYAALATLQARGLPLIDREPRPGIHDTLVAFVHPK
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHEEECCC
AGGQGVLVELVQHRSPHHR
CCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFTAIDHIGLVVADLDAAIDFYRTAYDVTEWERIELPERHALIGVARFGDVLIELIAPTS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCC
DQASFARFLREKGPGMHHIAYRVDDIYAALATLQARGLPLIDREPRPGIHDTLVAFVHPK
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHEEECCC
AGGQGVLVELVQHRSPHHR
CCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]