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The map label for this gene is degU [H]

Identifier: 222526082

GI number: 222526082

Start: 3503913

End: 3504623

Strand: Direct

Name: degU [H]

Synonym: Chy400_2839

Alternate gene names: 222526082

Gene position: 3503913-3504623 (Clockwise)

Preceding gene: 222526081

Following gene: 222526083

Centisome position: 66.5

GC content: 51.05

Gene sequence:

>711_bases
GTGACGGCACCGTCAAAAGTAAAAGTATTGATCATTGATGACCATCCGCTCTTCCGTCAAGGTATTCGCTGGAGTCTGGA
GAGTGCTCACGATATTGAGGTTGTAGGGGAAGCTGAGAACGGTCAGGAAGCGATCAAGCTGACCGAACGGCTCTTTCCCG
ATGTCGTCCTGGTTGATATTAATCTGCCCGGTTTGAATGGTCTGGAAGTCGCCCGTGTCATCAAGCGACGTGAACCGCGT
ACTGGCATTATTGTGTTGAGTGTTTACGAAGATGAAGAGCAACTCTTTCAGGCTATCAAGGTTGGAGCAGCAGCCTTCAC
CTCAAAAGACATCAGTCCCGAAGAGCTTGTTCACATGATTCGCGAGGTGGCGCGCGGTCGCTACCTGATCAATGATGCTG
TTCTGGCCCATCCCAACGTCGCTGCACGGGTGCTACACCAGTTTCGCGAACTGGCGGCAACCGATGAAGAGGACGGTGCA
AGTCTGTTTGCACCGCTTACATCACGTGAGATCGAAATTCTTGACTGTATTGCCCGTGGTCTCTCAAACAAAGAGATCGC
CAGCGAACTAAGCATCAGTAGTCAGACGGTGAAGAACCACATTACCTCCATCCTTGCCAAACTCCAGGTCAATGATCGCA
CGATGGCAGTGATTGTTGCGATCAAGAAGGGATGGATCAAAATGGGGTATTCGCAATCGTCTGAGGGGTGA

Upstream 100 bases:

>100_bases
CACTACGGAGAAGGCATAGAAATATGCTACTCGGATTACAGCAATCGTGGCAGCAACACCGTGTACGTGTATAACAGGGA
TCAACATTAAGGAGTCGTGT

Downstream 100 bases:

>100_bases
TCATTGGATTAGTGAGCATAACTACAAAATCGTAACGCTGGTGTACCTGAGTAACTGTTACGTATTCGACCGTGGGTGTC
AATAAGCAGCACTGTGAGAA

Product: LuxR family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MTAPSKVKVLIIDDHPLFRQGIRWSLESAHDIEVVGEAENGQEAIKLTERLFPDVVLVDINLPGLNGLEVARVIKRREPR
TGIIVLSVYEDEEQLFQAIKVGAAAFTSKDISPEELVHMIREVARGRYLINDAVLAHPNVAARVLHQFRELAATDEEDGA
SLFAPLTSREIEILDCIARGLSNKEIASELSISSQTVKNHITSILAKLQVNDRTMAVIVAIKKGWIKMGYSQSSEG

Sequences:

>Translated_236_residues
MTAPSKVKVLIIDDHPLFRQGIRWSLESAHDIEVVGEAENGQEAIKLTERLFPDVVLVDINLPGLNGLEVARVIKRREPR
TGIIVLSVYEDEEQLFQAIKVGAAAFTSKDISPEELVHMIREVARGRYLINDAVLAHPNVAARVLHQFRELAATDEEDGA
SLFAPLTSREIEILDCIARGLSNKEIASELSISSQTVKNHITSILAKLQVNDRTMAVIVAIKKGWIKMGYSQSSEG
>Mature_235_residues
TAPSKVKVLIIDDHPLFRQGIRWSLESAHDIEVVGEAENGQEAIKLTERLFPDVVLVDINLPGLNGLEVARVIKRREPRT
GIIVLSVYEDEEQLFQAIKVGAAAFTSKDISPEELVHMIREVARGRYLINDAVLAHPNVAARVLHQFRELAATDEEDGAS
LFAPLTSREIEILDCIARGLSNKEIASELSISSQTVKNHITSILAKLQVNDRTMAVIVAIKKGWIKMGYSQSSEG

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=226, Percent_Identity=38.0530973451327, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1788222, Length=219, Percent_Identity=34.703196347032, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787473, Length=201, Percent_Identity=39.8009950248756, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790102, Length=211, Percent_Identity=31.7535545023697, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788712, Length=204, Percent_Identity=28.4313725490196, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=26.5, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788546, Length=212, Percent_Identity=27.8301886792453, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082052, Length=85, Percent_Identity=40, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26085; Mature: 25954

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSKVKVLIIDDHPLFRQGIRWSLESAHDIEVVGEAENGQEAIKLTERLFPDVVLVDI
CCCCCEEEEEEECCCHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEE
NLPGLNGLEVARVIKRREPRTGIIVLSVYEDEEQLFQAIKVGAAAFTSKDISPEELVHMI
CCCCCCHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
REVARGRYLINDAVLAHPNVAARVLHQFRELAATDEEDGASLFAPLTSREIEILDCIARG
HHHHCCCEEECCCEECCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHC
LSNKEIASELSISSQTVKNHITSILAKLQVNDRTMAVIVAIKKGWIKMGYSQSSEG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCEEECCCCCCCC
>Mature Secondary Structure 
TAPSKVKVLIIDDHPLFRQGIRWSLESAHDIEVVGEAENGQEAIKLTERLFPDVVLVDI
CCCCEEEEEEECCCHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEE
NLPGLNGLEVARVIKRREPRTGIIVLSVYEDEEQLFQAIKVGAAAFTSKDISPEELVHMI
CCCCCCHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
REVARGRYLINDAVLAHPNVAARVLHQFRELAATDEEDGASLFAPLTSREIEILDCIARG
HHHHCCCEEECCCEECCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHC
LSNKEIASELSISSQTVKNHITSILAKLQVNDRTMAVIVAIKKGWIKMGYSQSSEG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]