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The map label for this gene is degS [H]

Identifier: 222526081

GI number: 222526081

Start: 3502765

End: 3503790

Strand: Direct

Name: degS [H]

Synonym: Chy400_2838

Alternate gene names: 222526081

Gene position: 3502765-3503790 (Clockwise)

Preceding gene: 222526080

Following gene: 222526082

Centisome position: 66.48

GC content: 58.77

Gene sequence:

>1026_bases
TTGAGTACGGAGCCAGCCGCCTTACTTGAGCGTGCCACAGCTATCGTTACCGCGCAATTAAACGAACTGCGCGATCTATA
TCACGCTGCGCTGCATCAGCACGAAGACATACGGCGGCGCGTCCAGCAACTCTCGCGCCAGCTTGACGAAGCCGTGATTC
AGGAACGCTTCGCGCGTGAGCGCGGCATGTCAACCGTTGCCGCAACTGCCCGCGTTAATCAGATACGGGCGGAACATGCG
GCGGCGGCGGCTACCGAAGCCGAACTACGGCGGGCTATGCGCCAGCTCGATCAGCTCATTCGTCAGATTGAGATGAGCAG
CACGACGTTAACGCGCAATGCAGAAGGTATCGCTGCCGATCCCTGGGTGCAGGCATTGCGTGCTCAGATTATCAAAGGCC
GTGAAGAAGAACGTATCCGACTGGCGCGTGAAGTTCACGATGGCCCGGCCCAGGTGCTGGCAAATGCGCTGATGGGAGTA
GAGGTGTGTCAGAACCTGCTCCAGGAACAACACCTCGACCGGTTAGGCTCAATTTTGAGCCAGTTGGGTGACAGTGTGCG
TGAAGGGTTGCGCGAGGTGCGCAGCTTTATCGCCGACCTGCGACCGGGTAAACTCGAAGAGCAAGGACTGGTCGCCGCGC
TTCACGAGTATATTCGGCGCTACCGCGACACGGTGAGCAATGCCGTTCACTTTGAAGCCGACCCACTGCCGCGACTACCA
GCCGAAGCCGAGATTGTGCTCTACCGCATCGTGCAGGAAGCCCTACAAAATGCCCGCAAACATGCCCGCGGTGCTCCGGT
ACGGGTCACCCTTACCACTCGCAACGGCCAGTTACAGCTCATCATCCGAGATGAAGGGCCAGGATTTGATCTGCGCGAAG
TAAGCCGACGTGCTGGCCGTGAAAGCTGGGGTCTGACCAGCATGCGCGAGCGTGCCGAACTCATCGGCGCTCAATTGACA
GTTACGACCCGTCACGGTGCGGGAACCGAGGTTCATGTGAAAATGCCATTACCTACTGCGCGTTAA

Upstream 100 bases:

>100_bases
GTAGAGCGAGATGACGGTTTCCTCATCTCGCTCCTCTTCATTGCGAACCGGTTGCGTGCTATACTTAGACCATCAATACA
TCAGACGTGGGAGTAGAGCC

Downstream 100 bases:

>100_bases
TTCTTGACTTCGTTTCGTTTTACACTACGGAGAAGGCATAGAAATATGCTACTCGGATTACAGCAATCGTGGCAGCAACA
CCGTGTACGTGTATAACAGG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSTEPAALLERATAIVTAQLNELRDLYHAALHQHEDIRRRVQQLSRQLDEAVIQERFARERGMSTVAATARVNQIRAEHA
AAAATEAELRRAMRQLDQLIRQIEMSSTTLTRNAEGIAADPWVQALRAQIIKGREEERIRLAREVHDGPAQVLANALMGV
EVCQNLLQEQHLDRLGSILSQLGDSVREGLREVRSFIADLRPGKLEEQGLVAALHEYIRRYRDTVSNAVHFEADPLPRLP
AEAEIVLYRIVQEALQNARKHARGAPVRVTLTTRNGQLQLIIRDEGPGFDLREVSRRAGRESWGLTSMRERAELIGAQLT
VTTRHGAGTEVHVKMPLPTAR

Sequences:

>Translated_341_residues
MSTEPAALLERATAIVTAQLNELRDLYHAALHQHEDIRRRVQQLSRQLDEAVIQERFARERGMSTVAATARVNQIRAEHA
AAAATEAELRRAMRQLDQLIRQIEMSSTTLTRNAEGIAADPWVQALRAQIIKGREEERIRLAREVHDGPAQVLANALMGV
EVCQNLLQEQHLDRLGSILSQLGDSVREGLREVRSFIADLRPGKLEEQGLVAALHEYIRRYRDTVSNAVHFEADPLPRLP
AEAEIVLYRIVQEALQNARKHARGAPVRVTLTTRNGQLQLIIRDEGPGFDLREVSRRAGRESWGLTSMRERAELIGAQLT
VTTRHGAGTEVHVKMPLPTAR
>Mature_340_residues
STEPAALLERATAIVTAQLNELRDLYHAALHQHEDIRRRVQQLSRQLDEAVIQERFARERGMSTVAATARVNQIRAEHAA
AAATEAELRRAMRQLDQLIRQIEMSSTTLTRNAEGIAADPWVQALRAQIIKGREEERIRLAREVHDGPAQVLANALMGVE
VCQNLLQEQHLDRLGSILSQLGDSVREGLREVRSFIADLRPGKLEEQGLVAALHEYIRRYRDTVSNAVHFEADPLPRLPA
EAEIVLYRIVQEALQNARKHARGAPVRVTLTTRNGQLQLIIRDEGPGFDLREVSRRAGRESWGLTSMRERAELIGAQLTV
TTRHGAGTEVHVKMPLPTAR

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=202, Percent_Identity=31.6831683168317, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788812, Length=202, Percent_Identity=30.1980198019802, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38298; Mature: 38167

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEPAALLERATAIVTAQLNELRDLYHAALHQHEDIRRRVQQLSRQLDEAVIQERFARE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGMSTVAATARVNQIRAEHAAAAATEAELRRAMRQLDQLIRQIEMSSTTLTRNAEGIAAD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PWVQALRAQIIKGREEERIRLAREVHDGPAQVLANALMGVEVCQNLLQEQHLDRLGSILS
HHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLGDSVREGLREVRSFIADLRPGKLEEQGLVAALHEYIRRYRDTVSNAVHFEADPLPRLP
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCC
AEAEIVLYRIVQEALQNARKHARGAPVRVTLTTRNGQLQLIIRDEGPGFDLREVSRRAGR
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHCCC
ESWGLTSMRERAELIGAQLTVTTRHGAGTEVHVKMPLPTAR
CCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCC
>Mature Secondary Structure 
STEPAALLERATAIVTAQLNELRDLYHAALHQHEDIRRRVQQLSRQLDEAVIQERFARE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGMSTVAATARVNQIRAEHAAAAATEAELRRAMRQLDQLIRQIEMSSTTLTRNAEGIAAD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PWVQALRAQIIKGREEERIRLAREVHDGPAQVLANALMGVEVCQNLLQEQHLDRLGSILS
HHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLGDSVREGLREVRSFIADLRPGKLEEQGLVAALHEYIRRYRDTVSNAVHFEADPLPRLP
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCC
AEAEIVLYRIVQEALQNARKHARGAPVRVTLTTRNGQLQLIIRDEGPGFDLREVSRRAGR
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHCCC
ESWGLTSMRERAELIGAQLTVTTRHGAGTEVHVKMPLPTAR
CCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]