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The map label for this gene is cpg2 [H]

Identifier: 222525951

GI number: 222525951

Start: 3341612

End: 3342748

Strand: Direct

Name: cpg2 [H]

Synonym: Chy400_2707

Alternate gene names: 222525951

Gene position: 3341612-3342748 (Clockwise)

Preceding gene: 222525947

Following gene: 222525952

Centisome position: 63.42

GC content: 61.39

Gene sequence:

>1137_bases
ATGCTTGACCGTGCGACCATTGCAGCCCACGAAGGCCGTTTGCTCGATCTGATTGCCCATCTCGTCCATATCGAATCGCC
CAGTACCGATAAACCACTGCTCGACAGGCTGGCCGATGAGCTGATGACGCTGTTCGCGCGGGTGGGAACTGTTGAACGAA
TTGCCAATCCGTCAGGGGGTGATCATGTACGAGTGATGGTTACCAATGCGAATGAACCATCGCTGCCGCCGACGCTGGTG
CTCTGCCATTACGATACCGTCTGGCCGGCAGGGACGGTCGCGCAACGTCCGTTTACTGTCACCGATGATCGGGCTTTTGG
GCCGGGTGCCTACGATATGAAGGCCAGTATTGCGATGATCTACGCGGCACTGGGTGGGTTTGGGCAACCGGCACCGGTGC
TGCGGCGGCCTGTCGTGTTGTTGTTGACGTCTGATGAGGAGATCGGTAGCCCGACCTCACGGGCGTTGATTGAAGCCACA
GCAGCGCAGGCGGCGCATGTGCTCGTGCTTGAACCACCGACCGAGCCGGATGGTGCCTTGAAGACGGCCCGCAAAGGTGG
CGGTGCCTTTCGCGTGACCATAACTGGACGGGCAGCGCACGCCGGGGTCGAACCTGAAAAGGGGGCGAGTGCCTTAACCG
AGCTGGCCCACCAGATTTTAGCCGTGAATGCACTGGCCAATCCGGCGCTGGGGACGACGGTTAATGTGGGGGTAGCCGGT
GGTGGTACCCGCCCGAATGTGGTACCGGCTGAAGCCTGGATGGATGTTGATGTGCGGGTCTGGACGCAGGCAGAGGCTGC
CCGGATCGAAGCCGGGATGGCTGCATTGCAGCCGGTGACTCCAGGGGTTCACCTCACGGTGCGCGGCAGCGTCCGGCGTC
CACCGATGGAACGAACACCGGCCAGTATCGCGCTCTTCGCGAAGGCTCAGGAACTCGGTGCTGCGCTCGGTTTGACGATC
CAGGAAGGCAGTACTGGTGGGGGCAGTGATGGCAATTTCACCGCTGCGCTCGGTATTCCTACTCTCGACGGTTTGGGATG
CCCCGGTGCCGGAGCGCACGCTGAACACGAGCAGATCAGCCGTCAGGGTCTGATTGATCGCACGGCATTGCTCTGTGCGC
TGCTTGAGACGTTGTAG

Upstream 100 bases:

>100_bases
ATGTAAACGGTATATGATTCATACTACCGACGCATAAGTTTCCAGTCGCTTTACGCTATACTATCCCCCATAACCGCCAT
CGCCATTTTGAGAGGGAATT

Downstream 100 bases:

>100_bases
GTTGGATGTCGGGGGAATGGGCGTGCTCCGGGTGGCTCCCGTAGAGGTTATTCCCGCCCCCCCTCCCGGCCTCCCCCCGC
TGGGGAGAGGAGACGAGCGG

Product: peptidase M20

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MLDRATIAAHEGRLLDLIAHLVHIESPSTDKPLLDRLADELMTLFARVGTVERIANPSGGDHVRVMVTNANEPSLPPTLV
LCHYDTVWPAGTVAQRPFTVTDDRAFGPGAYDMKASIAMIYAALGGFGQPAPVLRRPVVLLLTSDEEIGSPTSRALIEAT
AAQAAHVLVLEPPTEPDGALKTARKGGGAFRVTITGRAAHAGVEPEKGASALTELAHQILAVNALANPALGTTVNVGVAG
GGTRPNVVPAEAWMDVDVRVWTQAEAARIEAGMAALQPVTPGVHLTVRGSVRRPPMERTPASIALFAKAQELGAALGLTI
QEGSTGGGSDGNFTAALGIPTLDGLGCPGAGAHAEHEQISRQGLIDRTALLCALLETL

Sequences:

>Translated_378_residues
MLDRATIAAHEGRLLDLIAHLVHIESPSTDKPLLDRLADELMTLFARVGTVERIANPSGGDHVRVMVTNANEPSLPPTLV
LCHYDTVWPAGTVAQRPFTVTDDRAFGPGAYDMKASIAMIYAALGGFGQPAPVLRRPVVLLLTSDEEIGSPTSRALIEAT
AAQAAHVLVLEPPTEPDGALKTARKGGGAFRVTITGRAAHAGVEPEKGASALTELAHQILAVNALANPALGTTVNVGVAG
GGTRPNVVPAEAWMDVDVRVWTQAEAARIEAGMAALQPVTPGVHLTVRGSVRRPPMERTPASIALFAKAQELGAALGLTI
QEGSTGGGSDGNFTAALGIPTLDGLGCPGAGAHAEHEQISRQGLIDRTALLCALLETL
>Mature_378_residues
MLDRATIAAHEGRLLDLIAHLVHIESPSTDKPLLDRLADELMTLFARVGTVERIANPSGGDHVRVMVTNANEPSLPPTLV
LCHYDTVWPAGTVAQRPFTVTDDRAFGPGAYDMKASIAMIYAALGGFGQPAPVLRRPVVLLLTSDEEIGSPTSRALIEAT
AAQAAHVLVLEPPTEPDGALKTARKGGGAFRVTITGRAAHAGVEPEKGASALTELAHQILAVNALANPALGTTVNVGVAG
GGTRPNVVPAEAWMDVDVRVWTQAEAARIEAGMAALQPVTPGVHLTVRGSVRRPPMERTPASIALFAKAQELGAALGLTI
QEGSTGGGSDGNFTAALGIPTLDGLGCPGAGAHAEHEQISRQGLIDRTALLCALLETL

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 39177; Mature: 39177

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRATIAAHEGRLLDLIAHLVHIESPSTDKPLLDRLADELMTLFARVGTVERIANPSGG
CCCCCEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
DHVRVMVTNANEPSLPPTLVLCHYDTVWPAGTVAQRPFTVTDDRAFGPGAYDMKASIAMI
CEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHH
YAALGGFGQPAPVLRRPVVLLLTSDEEIGSPTSRALIEATAAQAAHVLVLEPPTEPDGAL
HHHHCCCCCCCHHHCCCEEEEEECCHHHCCCHHHHHHHHHHHCCEEEEEECCCCCCCHHH
KTARKGGGAFRVTITGRAAHAGVEPEKGASALTELAHQILAVNALANPALGTTVNVGVAG
HHHHCCCCEEEEEEECCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
GGTRPNVVPAEAWMDVDVRVWTQAEAARIEAGMAALQPVTPGVHLTVRGSVRRPPMERTP
CCCCCCEEEHHHHEECEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC
ASIALFAKAQELGAALGLTIQEGSTGGGSDGNFTAALGIPTLDGLGCPGAGAHAEHEQIS
CEEEEEEEHHHHHHHHCEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
RQGLIDRTALLCALLETL
HHCCHHHHHHHHHHHHHC
>Mature Secondary Structure
MLDRATIAAHEGRLLDLIAHLVHIESPSTDKPLLDRLADELMTLFARVGTVERIANPSGG
CCCCCEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
DHVRVMVTNANEPSLPPTLVLCHYDTVWPAGTVAQRPFTVTDDRAFGPGAYDMKASIAMI
CEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHH
YAALGGFGQPAPVLRRPVVLLLTSDEEIGSPTSRALIEATAAQAAHVLVLEPPTEPDGAL
HHHHCCCCCCCHHHCCCEEEEEECCHHHCCCHHHHHHHHHHHCCEEEEEECCCCCCCHHH
KTARKGGGAFRVTITGRAAHAGVEPEKGASALTELAHQILAVNALANPALGTTVNVGVAG
HHHHCCCCEEEEEEECCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
GGTRPNVVPAEAWMDVDVRVWTQAEAARIEAGMAALQPVTPGVHLTVRGSVRRPPMERTP
CCCCCCEEEHHHHEECEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC
ASIALFAKAQELGAALGLTIQEGSTGGGSDGNFTAALGIPTLDGLGCPGAGAHAEHEQIS
CEEEEEEEHHHHHHHHCEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
RQGLIDRTALLCALLETL
HHCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]