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The map label for this gene is resE [H]

Identifier: 222524780

GI number: 222524780

Start: 1907490

End: 1909745

Strand: Direct

Name: resE [H]

Synonym: Chy400_1507

Alternate gene names: 222524780

Gene position: 1907490-1909745 (Clockwise)

Preceding gene: 222524775

Following gene: 222524781

Centisome position: 36.2

GC content: 51.95

Gene sequence:

>2256_bases
ATGAGTCGGCTGATTGGCGAGCTGCAAAAACAGCTCAAATACCAGATTATCGGCCCCTTCCTCCTCCTTGCGATTGTGGT
AGCAATCGTAGGATTGACGATTGTCGCTTTTTTTCTCGCCCGTCAACAACAGGATCGCTTTGACAACGAGCTGGCCGCAG
CAACTCGCACGGTTAGCGATGCCTTTCTTGCTCAGGAACAGGCGAATCTCAACTTTTTACGCGAAGTAGCTTTCGCCCAG
CGCAACGAGAGCATCAATGCACCGGCAGTGGCCGACGCATTCTATGAAAACAACGTTGAAGGTTTGCGGCTCGCCCTCGA
ACCTTTCTTCCTGCAAGGTACCCGTCGCAGTGATGTCCGCCTTGACCGGTTGATGGCATTTGACCGCAGCGGTCGCACGA
TTGTCGATTTTGAGCGGCCACCGCTCGCCGGTGAAGAGACATATATTACTCATGACTCAATTGATCTCAGCAGTGCCTGG
TTTACGTCACGCATCCTCAATGGTGAGGCCGATGAGCGTGGTGATAAATACGCCGGCCTGATCCAGTTTAGCAATACGCA
GACGCTCTACCTGGCAACTATCGCACCGGTACGACGGGGTAATGAGGTGGTTGGCGGCCTGATCGTAGCAATTCGTATCG
ATAACCTGCTCAACACCGTTGTACAACAATCCCGATTAGATGGAATCATTCTCTACGATCAGGAAGGAAATCTGATAGCC
ACTACCTTTAGCAGTCAGGCGCGACCTGCACCGCTGCGGCAAGAGCTGGTTTCACAGGTTAAAGCCAATCCTGATCCATA
TGGACAAACCCTCTTCACCATCGAAACGATCAATGGTGTCGAGTATCAATTTGCTTATGTACCGTTAACCATCCGTGGGG
GACGTGCTGGTATCATGGCAACAGCCCGTACCCGCGAAGAGGTGCTGTTAACGTGGAACAATATCAGCCCATTGCTGGTA
CTGATCACCTTCAGCTTAGGCCTGGGCATTGCCGTACTCGGTTTGTGGGTAGCCCGTCGCATTACCCGCCCCCTCGAAGA
ACTGGCGGAAACAGCCAGTGCCATCGTGAACGGCGATCTGCAACGACGTGCGTCAGTGAATACGCAGAACGAGATTGGTG
TGTTGGCTCGACAATTCAATCGAATGACCGAGTACCTGATTGAATTACTTGCCCAGGTACGTGCCGAAGCTCGCCAGCGC
ACTGCAATCGTCGAAAGTATCACCGACGGTATTATCTTTATTGATGTCCATGGCGAGATTCGTTCTATTAATCGCGCTAC
ACGCCGCCTGCTTGGTTTGAGTGATGATACAGCCCTACCCAAACGCCTCAGTGATCTACCGCTCGAACCACTGACTGAAG
GTATTCCGGGCTTTGGCGATCAACGTGCCCAAAATCTCTATACCCTTGGCGATTATATTGTTCGGCTGTCAGTCGAAGAT
GTACGTGAAGATGATGGGCATCTGTTAGGGTATGTCGCCGTCTTGCAAGACCTCACCGAAGAGGTGATGGTCGACCGGGC
AAAAACAAACTTTATCGGTACAATTTCCCACGAGCTTCGCACTCCACTCACGGTCATTCGTGGGAACGCCGATCTGCTGG
CGCGTGGTCTGGCCGGACCACTCGAAGATGAACAGAAGAGCTTCGTTGAAGCAATTCGGTTGCAGGCAAACAACATGACA
AACCTGATTAGCAATGTCATCACCATTGCTAATCTCGACTCTGGTTCACTGAAATCCACTCTCGAACCGATTGAGGTGCA
GCGGCCAATCGAAGATGCAATCTGGCAGACGCAAGGACAGATCAAAGCAAAGGGATTGCGGCTTGAAGTTGAAATACCAA
AGAAGTTGCCAAAGGTCCTGGCCGATTTCGATCATGTCCGCACCATCATGCTTCAGTTGCTTGACAATGCCCGGCGTTAT
ACGAGTGCCGGTACTATCACCGTTCGTGTTATGCCTCAACCTGATACATTGCGGATTGAGGTTAGTGATACAGGGCGTGG
CATCCCACCCAACTTGCATCAACAAATCTTCGAGCGCTTCTTTCGCGGTGATGGGACAAGTGAGGGGATTAATTCCAGCG
AACGTGGCATTGGATTGGGCTTAGCTATTTGCAAGCAACTGATCGAGCGTCTAGGGGGGACGATCGGCGTCGAGAGTGCG
CCAGGTCAGGGAAGTACGTTCTTCTTCACATTACGGTACGCCGATGATACCGCCACTCCTGAAAAACCAGCAACCGGCCT
GGAATCGGCTGCTTGA

Upstream 100 bases:

>100_bases
ATGCACGTGGAAGTACAGTACGTCACTCAGACAGACAGGCTTATGACACGCATCCTTTTCGCTGTCGGACGACAAACCAA
CGTACTACAGGAAGACAGTC

Downstream 100 bases:

>100_bases
CCGTGATCGTCTCCGACGACCATTGCCCTGGCTGATTCTCGGCTCTCTGTTGCTATTACTGCTGCTGATCTCGCTTGTGA
TCAACCTGATGATCGATCAG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 751; Mature: 750

Protein sequence:

>751_residues
MSRLIGELQKQLKYQIIGPFLLLAIVVAIVGLTIVAFFLARQQQDRFDNELAAATRTVSDAFLAQEQANLNFLREVAFAQ
RNESINAPAVADAFYENNVEGLRLALEPFFLQGTRRSDVRLDRLMAFDRSGRTIVDFERPPLAGEETYITHDSIDLSSAW
FTSRILNGEADERGDKYAGLIQFSNTQTLYLATIAPVRRGNEVVGGLIVAIRIDNLLNTVVQQSRLDGIILYDQEGNLIA
TTFSSQARPAPLRQELVSQVKANPDPYGQTLFTIETINGVEYQFAYVPLTIRGGRAGIMATARTREEVLLTWNNISPLLV
LITFSLGLGIAVLGLWVARRITRPLEELAETASAIVNGDLQRRASVNTQNEIGVLARQFNRMTEYLIELLAQVRAEARQR
TAIVESITDGIIFIDVHGEIRSINRATRRLLGLSDDTALPKRLSDLPLEPLTEGIPGFGDQRAQNLYTLGDYIVRLSVED
VREDDGHLLGYVAVLQDLTEEVMVDRAKTNFIGTISHELRTPLTVIRGNADLLARGLAGPLEDEQKSFVEAIRLQANNMT
NLISNVITIANLDSGSLKSTLEPIEVQRPIEDAIWQTQGQIKAKGLRLEVEIPKKLPKVLADFDHVRTIMLQLLDNARRY
TSAGTITVRVMPQPDTLRIEVSDTGRGIPPNLHQQIFERFFRGDGTSEGINSSERGIGLGLAICKQLIERLGGTIGVESA
PGQGSTFFFTLRYADDTATPEKPATGLESAA

Sequences:

>Translated_751_residues
MSRLIGELQKQLKYQIIGPFLLLAIVVAIVGLTIVAFFLARQQQDRFDNELAAATRTVSDAFLAQEQANLNFLREVAFAQ
RNESINAPAVADAFYENNVEGLRLALEPFFLQGTRRSDVRLDRLMAFDRSGRTIVDFERPPLAGEETYITHDSIDLSSAW
FTSRILNGEADERGDKYAGLIQFSNTQTLYLATIAPVRRGNEVVGGLIVAIRIDNLLNTVVQQSRLDGIILYDQEGNLIA
TTFSSQARPAPLRQELVSQVKANPDPYGQTLFTIETINGVEYQFAYVPLTIRGGRAGIMATARTREEVLLTWNNISPLLV
LITFSLGLGIAVLGLWVARRITRPLEELAETASAIVNGDLQRRASVNTQNEIGVLARQFNRMTEYLIELLAQVRAEARQR
TAIVESITDGIIFIDVHGEIRSINRATRRLLGLSDDTALPKRLSDLPLEPLTEGIPGFGDQRAQNLYTLGDYIVRLSVED
VREDDGHLLGYVAVLQDLTEEVMVDRAKTNFIGTISHELRTPLTVIRGNADLLARGLAGPLEDEQKSFVEAIRLQANNMT
NLISNVITIANLDSGSLKSTLEPIEVQRPIEDAIWQTQGQIKAKGLRLEVEIPKKLPKVLADFDHVRTIMLQLLDNARRY
TSAGTITVRVMPQPDTLRIEVSDTGRGIPPNLHQQIFERFFRGDGTSEGINSSERGIGLGLAICKQLIERLGGTIGVESA
PGQGSTFFFTLRYADDTATPEKPATGLESAA
>Mature_750_residues
SRLIGELQKQLKYQIIGPFLLLAIVVAIVGLTIVAFFLARQQQDRFDNELAAATRTVSDAFLAQEQANLNFLREVAFAQR
NESINAPAVADAFYENNVEGLRLALEPFFLQGTRRSDVRLDRLMAFDRSGRTIVDFERPPLAGEETYITHDSIDLSSAWF
TSRILNGEADERGDKYAGLIQFSNTQTLYLATIAPVRRGNEVVGGLIVAIRIDNLLNTVVQQSRLDGIILYDQEGNLIAT
TFSSQARPAPLRQELVSQVKANPDPYGQTLFTIETINGVEYQFAYVPLTIRGGRAGIMATARTREEVLLTWNNISPLLVL
ITFSLGLGIAVLGLWVARRITRPLEELAETASAIVNGDLQRRASVNTQNEIGVLARQFNRMTEYLIELLAQVRAEARQRT
AIVESITDGIIFIDVHGEIRSINRATRRLLGLSDDTALPKRLSDLPLEPLTEGIPGFGDQRAQNLYTLGDYIVRLSVEDV
REDDGHLLGYVAVLQDLTEEVMVDRAKTNFIGTISHELRTPLTVIRGNADLLARGLAGPLEDEQKSFVEAIRLQANNMTN
LISNVITIANLDSGSLKSTLEPIEVQRPIEDAIWQTQGQIKAKGLRLEVEIPKKLPKVLADFDHVRTIMLQLLDNARRYT
SAGTITVRVMPQPDTLRIEVSDTGRGIPPNLHQQIFERFFRGDGTSEGINSSERGIGLGLAICKQLIERLGGTIGVESAP
GQGSTFFFTLRYADDTATPEKPATGLESAA

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=229, Percent_Identity=34.061135371179, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI145693157, Length=225, Percent_Identity=34.6666666666667, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=30.4347826086957, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=29.7413793103448, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI87081816, Length=243, Percent_Identity=30.0411522633745, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788393, Length=218, Percent_Identity=28.8990825688073, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1786600, Length=243, Percent_Identity=30.0411522633745, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788713, Length=266, Percent_Identity=28.1954887218045, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=28.5106382978723, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=362, Percent_Identity=25.1381215469613, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=25.6880733944954, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790300, Length=349, Percent_Identity=26.647564469914, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790567, Length=356, Percent_Identity=28.3707865168539, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=26.8518518518519, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=27.3127753303965, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=25, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=80, Percent_Identity=45, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83043; Mature: 82912

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLIGELQKQLKYQIIGPFLLLAIVVAIVGLTIVAFFLARQQQDRFDNELAAATRTVSD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFLAQEQANLNFLREVAFAQRNESINAPAVADAFYENNVEGLRLALEPFFLQGTRRSDVR
HHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEECHHHCCCCCCCHHH
LDRLMAFDRSGRTIVDFERPPLAGEETYITHDSIDLSSAWFTSRILNGEADERGDKYAGL
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEE
IQFSNTQTLYLATIAPVRRGNEVVGGLIVAIRIDNLLNTVVQQSRLDGIILYDQEGNLIA
EEECCCCEEEEEEECCHHCCCHHHHHEEEEEEHHHHHHHHHHHHCCCEEEEEECCCCEEE
TTFSSQARPAPLRQELVSQVKANPDPYGQTLFTIETINGVEYQFAYVPLTIRGGRAGIMA
EECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCEEEEEEEEEEEECCCCCEEE
TARTREEVLLTWNNISPLLVLITFSLGLGIAVLGLWVARRITRPLEELAETASAIVNGDL
ECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QRRASVNTQNEIGVLARQFNRMTEYLIELLAQVRAEARQRTAIVESITDGIIFIDVHGEI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHH
RSINRATRRLLGLSDDTALPKRLSDLPLEPLTEGIPGFGDQRAQNLYTLGDYIVRLSVED
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHEEEEHHH
VREDDGHLLGYVAVLQDLTEEVMVDRAKTNFIGTISHELRTPLTVIRGNADLLARGLAGP
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCEEEEECCHHHHHHHCCCC
LEDEQKSFVEAIRLQANNMTNLISNVITIANLDSGSLKSTLEPIEVQRPIEDAIWQTQGQ
CCHHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCCHHHHCCCHHHCCCHHHHHHHCCCC
IKAKGLRLEVEIPKKLPKVLADFDHVRTIMLQLLDNARRYTSAGTITVRVMPQPDTLRIE
EEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEE
VSDTGRGIPPNLHQQIFERFFRGDGTSEGINSSERGIGLGLAICKQLIERLGGTIGVESA
ECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCC
PGQGSTFFFTLRYADDTATPEKPATGLESAA
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRLIGELQKQLKYQIIGPFLLLAIVVAIVGLTIVAFFLARQQQDRFDNELAAATRTVSD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFLAQEQANLNFLREVAFAQRNESINAPAVADAFYENNVEGLRLALEPFFLQGTRRSDVR
HHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEECHHHCCCCCCCHHH
LDRLMAFDRSGRTIVDFERPPLAGEETYITHDSIDLSSAWFTSRILNGEADERGDKYAGL
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEE
IQFSNTQTLYLATIAPVRRGNEVVGGLIVAIRIDNLLNTVVQQSRLDGIILYDQEGNLIA
EEECCCCEEEEEEECCHHCCCHHHHHEEEEEEHHHHHHHHHHHHCCCEEEEEECCCCEEE
TTFSSQARPAPLRQELVSQVKANPDPYGQTLFTIETINGVEYQFAYVPLTIRGGRAGIMA
EECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCEEEEEEEEEEEECCCCCEEE
TARTREEVLLTWNNISPLLVLITFSLGLGIAVLGLWVARRITRPLEELAETASAIVNGDL
ECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QRRASVNTQNEIGVLARQFNRMTEYLIELLAQVRAEARQRTAIVESITDGIIFIDVHGEI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHH
RSINRATRRLLGLSDDTALPKRLSDLPLEPLTEGIPGFGDQRAQNLYTLGDYIVRLSVED
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHEEEEHHH
VREDDGHLLGYVAVLQDLTEEVMVDRAKTNFIGTISHELRTPLTVIRGNADLLARGLAGP
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCEEEEECCHHHHHHHCCCC
LEDEQKSFVEAIRLQANNMTNLISNVITIANLDSGSLKSTLEPIEVQRPIEDAIWQTQGQ
CCHHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCCHHHHCCCHHHCCCHHHHHHHCCCC
IKAKGLRLEVEIPKKLPKVLADFDHVRTIMLQLLDNARRYTSAGTITVRVMPQPDTLRIE
EEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEE
VSDTGRGIPPNLHQQIFERFFRGDGTSEGINSSERGIGLGLAICKQLIERLGGTIGVESA
ECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCC
PGQGSTFFFTLRYADDTATPEKPATGLESAA
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]