Click here to switch to the map view.

The map label for this gene is gltC [H]

Identifier: 222524698

GI number: 222524698

Start: 1808949

End: 1809854

Strand: Direct

Name: gltC [H]

Synonym: Chy400_1425

Alternate gene names: 222524698

Gene position: 1808949-1809854 (Clockwise)

Preceding gene: 222524692

Following gene: 222524706

Centisome position: 34.33

GC content: 58.83

Gene sequence:

>906_bases
ATGGAACTTCGCCATCTGCGCTACTTTGAAGCCGTAGCCCGTCATTCACACGTGACTCGCGCCGCAGCCGAGCTGCATAT
CGCCCAACCAGCACTCAGTAAGCAGATCAGTCAGCTTGAACGGGAACTGGGTATTACCCTCTTTGATCGGGTAGGGCGTA
GTTTACGCCTGACAGAAGCTGGTGAAGCTCTGTTACCGTATGCGCGGGCCATTCTTGCTCAGGTCGAAGAGGCACGGGCT
GCGATGGCCGAGCGCATTGGCTTGAAAGCCGGTCGGGTTACCATAGGCGCACCTCCAACCGTGGGTGCCCATCTCTTGCC
ACCACTGCTCACCATCTTTCATCAGCGGTATCCCGGTATCACGTTGCGCCTGCACGAGGCAGGGATACAGTCACTGCTCG
ATCTGCTGGAAGCCGGTATCACTGATCTAGCCGTTGTTGCGCTGCCGGTGACCGATGAACAGTTGACGGTAACCCCGCTG
TTGAACGAGCCGCTGGTTCTGATTGTCAGTACGACCCACCCACTGGCCCGGCGCAGTGAAGTGATGATGACGGAGTTGCG
TCACGAACGCTGGATTCTATCCCCATCAAGCTATGAGTTGCGCGAAGCAACCTTAAAGGCCTGTCGCGAGGCTGGTTTTA
CGCCTCAGACCGTGCTGGAGGGCGGGGAAACGGAAACCCTGGTGCGGTTTGTGGCCGCCGGATTGGGAGTGTCGCTGGTA
CCTGCCCTGGCTGTCGCCGGTTGTACTGATGTCGTGCGCCTAACGGTGTCTGACCAACATCTGACCCGTTCACTCGGCCT
GGTCTGGCGGAGTGATCGCACAGCTTCGCCGGCAGCCCGTGCCTTGCGCGAGTTTCTGGTGAACGAAGTGCGCCAGCGGC
CAATTGAGACCTTTATCCGTCCCTAA

Upstream 100 bases:

>100_bases
AATGACACGTCCACCTCAATTGTCAAGTCCTAACGCACATAACCGGCGGGATTTGGTATCATACCATGCAGAGTGTTCGC
TAATACGGAAGGGCAAGAGT

Downstream 100 bases:

>100_bases
GCTGTTCAAGCCGGGCAAAACTCGCCAATAGTCGGCGTTCGCGATCAGCAAAACGGACGGTCACCTCTTCATCACCTTCG
ATCAGGCGGCTGTCAACGAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MELRHLRYFEAVARHSHVTRAAAELHIAQPALSKQISQLERELGITLFDRVGRSLRLTEAGEALLPYARAILAQVEEARA
AMAERIGLKAGRVTIGAPPTVGAHLLPPLLTIFHQRYPGITLRLHEAGIQSLLDLLEAGITDLAVVALPVTDEQLTVTPL
LNEPLVLIVSTTHPLARRSEVMMTELRHERWILSPSSYELREATLKACREAGFTPQTVLEGGETETLVRFVAAGLGVSLV
PALAVAGCTDVVRLTVSDQHLTRSLGLVWRSDRTASPAARALREFLVNEVRQRPIETFIRP

Sequences:

>Translated_301_residues
MELRHLRYFEAVARHSHVTRAAAELHIAQPALSKQISQLERELGITLFDRVGRSLRLTEAGEALLPYARAILAQVEEARA
AMAERIGLKAGRVTIGAPPTVGAHLLPPLLTIFHQRYPGITLRLHEAGIQSLLDLLEAGITDLAVVALPVTDEQLTVTPL
LNEPLVLIVSTTHPLARRSEVMMTELRHERWILSPSSYELREATLKACREAGFTPQTVLEGGETETLVRFVAAGLGVSLV
PALAVAGCTDVVRLTVSDQHLTRSLGLVWRSDRTASPAARALREFLVNEVRQRPIETFIRP
>Mature_301_residues
MELRHLRYFEAVARHSHVTRAAAELHIAQPALSKQISQLERELGITLFDRVGRSLRLTEAGEALLPYARAILAQVEEARA
AMAERIGLKAGRVTIGAPPTVGAHLLPPLLTIFHQRYPGITLRLHEAGIQSLLDLLEAGITDLAVVALPVTDEQLTVTPL
LNEPLVLIVSTTHPLARRSEVMMTELRHERWILSPSSYELREATLKACREAGFTPQTVLEGGETETLVRFVAAGLGVSLV
PALAVAGCTDVVRLTVSDQHLTRSLGLVWRSDRTASPAARALREFLVNEVRQRPIETFIRP

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=280, Percent_Identity=36.0714285714286, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1790399, Length=296, Percent_Identity=36.4864864864865, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1787879, Length=298, Percent_Identity=35.2348993288591, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=30.7958477508651, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1788887, Length=292, Percent_Identity=32.1917808219178, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787530, Length=275, Percent_Identity=29.4545454545455, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788748, Length=293, Percent_Identity=30.0341296928328, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI2367136, Length=247, Percent_Identity=32.7935222672065, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787806, Length=304, Percent_Identity=27.6315789473684, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788481, Length=284, Percent_Identity=27.8169014084507, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788297, Length=295, Percent_Identity=31.5254237288136, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787601, Length=176, Percent_Identity=30.1136363636364, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790208, Length=295, Percent_Identity=27.4576271186441, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790262, Length=245, Percent_Identity=27.7551020408163, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082132, Length=284, Percent_Identity=26.7605633802817, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87081904, Length=302, Percent_Identity=28.1456953642384, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789173, Length=123, Percent_Identity=41.4634146341463, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789506, Length=288, Percent_Identity=23.2638888888889, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786401, Length=307, Percent_Identity=26.3843648208469, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=28.3950617283951, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789204, Length=256, Percent_Identity=26.5625, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994962, Length=157, Percent_Identity=33.7579617834395, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790011, Length=265, Percent_Identity=25.6603773584906, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788706, Length=174, Percent_Identity=31.6091954022989, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789639, Length=248, Percent_Identity=25, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787128, Length=172, Percent_Identity=30.2325581395349, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87082024, Length=178, Percent_Identity=28.6516853932584, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33099; Mature: 33099

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRHLRYFEAVARHSHVTRAAAELHIAQPALSKQISQLERELGITLFDRVGRSLRLTEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEECCC
GEALLPYARAILAQVEEARAAMAERIGLKAGRVTIGAPPTVGAHLLPPLLTIFHQRYPGI
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCE
TLRLHEAGIQSLLDLLEAGITDLAVVALPVTDEQLTVTPLLNEPLVLIVSTTHPLARRSE
EEEEHHHHHHHHHHHHHCCCHHHEEEEEECCCCCEEEEEECCCCEEEEEECCCCHHHHHH
VMMTELRHERWILSPSSYELREATLKACREAGFTPQTVLEGGETETLVRFVAAGLGVSLV
HHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCCHHHH
PALAVAGCTDVVRLTVSDQHLTRSLGLVWRSDRTASPAARALREFLVNEVRQRPIETFIR
HHHHHHCCCHHEEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHCC
P
C
>Mature Secondary Structure
MELRHLRYFEAVARHSHVTRAAAELHIAQPALSKQISQLERELGITLFDRVGRSLRLTEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEECCC
GEALLPYARAILAQVEEARAAMAERIGLKAGRVTIGAPPTVGAHLLPPLLTIFHQRYPGI
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCE
TLRLHEAGIQSLLDLLEAGITDLAVVALPVTDEQLTVTPLLNEPLVLIVSTTHPLARRSE
EEEEHHHHHHHHHHHHHCCCHHHEEEEEECCCCCEEEEEECCCCEEEEEECCCCHHHHHH
VMMTELRHERWILSPSSYELREATLKACREAGFTPQTVLEGGETETLVRFVAAGLGVSLV
HHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCCHHHH
PALAVAGCTDVVRLTVSDQHLTRSLGLVWRSDRTASPAARALREFLVNEVRQRPIETFIR
HHHHHHCCCHHEEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]