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The map label for this gene is obg

Identifier: 222524679

GI number: 222524679

Start: 1788709

End: 1790028

Strand: Direct

Name: obg

Synonym: Chy400_1406

Alternate gene names: 222524679

Gene position: 1788709-1790028 (Clockwise)

Preceding gene: 222524678

Following gene: 222524680

Centisome position: 33.95

GC content: 57.65

Gene sequence:

>1320_bases
ATGAAAACTGAAACCGATTTCTTTGATCAGGCAACAATTGTAGTACGTGCCGGTAACGGTGGTAACGGTGCGGCCACATT
CCGGCGTGAAAAATATGTTCCGCGTGGCGGCCCCAATGGCGGTGATGGTGGTCGTGGAGGTCACGTCTATCTGATCGCCG
ATCCTGAATACAACACGCTGCTCCATTTTCGCTATCAGCGCAAGTTCGTTGCCGAAAATGGTGGGCACGGTGGCAAAAAT
GCGATGCATGGGCGCAACGGCACTGATGTCTACGTACCGGTACCACCGGGCACAGTAGTGCGGGCAACTATCGACGGCGT
TACGTACAGTGTCGATCTGGCCCGCCCTGGTCAACGCCTGCTCGCCGCTCGCGGGGGACGTGGTGGGTTGGGCAACATCC
ACTTCGCAACCTCGACTCGCCAGGCACCGCGGCTTGCTGAATTGGGAGAACCGGGCCAGGAGTTGACCCTTGAACTTGAG
CTAAAGATGTTGGCCGATGTAGGGCTGGTCGGTTTTCCGAACGCCGGGAAGTCTACGCTGCTGTCGGTCATTAGCGCCGC
CCGCCCGAAGATTGCCGCCTATCCCTTTACCACACTCACTCCGAACCTGGGTATTGTCGAAGTTGGCCTGCAACGCTTTG
TGGTAGCCGACATTCCCGGTTTGATCGAGGGCGCTCACGCCGGCGTGGGTCTCGGTCACGATTTTCTGCGCCATGTCGAA
CGTACCCGGCTGTTGATCCATATTATCGATGCCGCTGGTGTCGATGGTCGTTATCCCTGGGATGATTACGAGCAGATCAA
CACCGAGCTGCGCCTCTATCAGCCTGAACTTGCCCAACGCAAGCAGGTCGTGGCTCTCAATAAAGCCGATCTACCCGCTG
CCCAGGAAAATCTGCCGATCTTACGTGAACGATTGCCGGTGGCTCCTGAAGACCTCTTCGTGATCTCTGCGGCCACCGGT
GAGGGTATCGAACCCCTCCTGCGCCGGGTTGCCGACCTTTTGCGGGCCGATCCTCCACCACAGCGCGATCCGGTCGATCC
CGACGAACCACCCCTACAGTGGCCTCTGCCAGAGGTTGATGAGAATGCCTTTACCATCGAACGTGAAGGTGAGGCTTTCC
GGGTACGTGGGATCAAGATTGAACGCTTGATCGCGATGAGCAATCTCGATCAAGATGAAGCGCTCGACCGGATTCAGCGC
GTCCTTGAGGCGAGTGGGATTAACGAAGCCCTGATTGCGGCCGGCGTGCAGGACGGTGATCTGGTACGGATTGGACGGGC
TGAATTAGTCTGGGATGATAGCGGACAGCATGCCTTATGA

Upstream 100 bases:

>100_bases
TGTCCGCTCTGCATACCTCACTCGGACGTATAATGAAAGCTGACCGTTAAAAATAAACGCAATTTGGGGGCGTCATCAGA
CACCCCATGTTGATACGCTT

Downstream 100 bases:

>100_bases
CAACAACGAACCAACCTACAAACCCACCACCGGCGCCATCGGCGCCGCCGACCGATCAGATCGTTCAGACCCATCATTCA
GTGACGATTAACGGGGTGGA

Product: GTP-binding protein Obg/CgtA

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKTETDFFDQATIVVRAGNGGNGAATFRREKYVPRGGPNGGDGGRGGHVYLIADPEYNTLLHFRYQRKFVAENGGHGGKN
AMHGRNGTDVYVPVPPGTVVRATIDGVTYSVDLARPGQRLLAARGGRGGLGNIHFATSTRQAPRLAELGEPGQELTLELE
LKMLADVGLVGFPNAGKSTLLSVISAARPKIAAYPFTTLTPNLGIVEVGLQRFVVADIPGLIEGAHAGVGLGHDFLRHVE
RTRLLIHIIDAAGVDGRYPWDDYEQINTELRLYQPELAQRKQVVALNKADLPAAQENLPILRERLPVAPEDLFVISAATG
EGIEPLLRRVADLLRADPPPQRDPVDPDEPPLQWPLPEVDENAFTIEREGEAFRVRGIKIERLIAMSNLDQDEALDRIQR
VLEASGINEALIAAGVQDGDLVRIGRAELVWDDSGQHAL

Sequences:

>Translated_439_residues
MKTETDFFDQATIVVRAGNGGNGAATFRREKYVPRGGPNGGDGGRGGHVYLIADPEYNTLLHFRYQRKFVAENGGHGGKN
AMHGRNGTDVYVPVPPGTVVRATIDGVTYSVDLARPGQRLLAARGGRGGLGNIHFATSTRQAPRLAELGEPGQELTLELE
LKMLADVGLVGFPNAGKSTLLSVISAARPKIAAYPFTTLTPNLGIVEVGLQRFVVADIPGLIEGAHAGVGLGHDFLRHVE
RTRLLIHIIDAAGVDGRYPWDDYEQINTELRLYQPELAQRKQVVALNKADLPAAQENLPILRERLPVAPEDLFVISAATG
EGIEPLLRRVADLLRADPPPQRDPVDPDEPPLQWPLPEVDENAFTIEREGEAFRVRGIKIERLIAMSNLDQDEALDRIQR
VLEASGINEALIAAGVQDGDLVRIGRAELVWDDSGQHAL
>Mature_439_residues
MKTETDFFDQATIVVRAGNGGNGAATFRREKYVPRGGPNGGDGGRGGHVYLIADPEYNTLLHFRYQRKFVAENGGHGGKN
AMHGRNGTDVYVPVPPGTVVRATIDGVTYSVDLARPGQRLLAARGGRGGLGNIHFATSTRQAPRLAELGEPGQELTLELE
LKMLADVGLVGFPNAGKSTLLSVISAARPKIAAYPFTTLTPNLGIVEVGLQRFVVADIPGLIEGAHAGVGLGHDFLRHVE
RTRLLIHIIDAAGVDGRYPWDDYEQINTELRLYQPELAQRKQVVALNKADLPAAQENLPILRERLPVAPEDLFVISAATG
EGIEPLLRRVADLLRADPPPQRDPVDPDEPPLQWPLPEVDENAFTIEREGEAFRVRGIKIERLIAMSNLDQDEALDRIQR
VLEASGINEALIAAGVQDGDLVRIGRAELVWDDSGQHAL

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=351, Percent_Identity=43.5897435897436, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI111955139, Length=317, Percent_Identity=37.2239747634069, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI111955063, Length=246, Percent_Identity=38.6178861788618, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI58761500, Length=135, Percent_Identity=34.0740740740741, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4758796, Length=87, Percent_Identity=39.0804597701149, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI4557537, Length=88, Percent_Identity=38.6363636363636, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789574, Length=353, Percent_Identity=45.3257790368272, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1787454, Length=166, Percent_Identity=33.7349397590361, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17508313, Length=329, Percent_Identity=40.7294832826748, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17552324, Length=352, Percent_Identity=27.8409090909091, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=35.15625, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=91, Percent_Identity=38.4615384615385, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555344, Length=87, Percent_Identity=37.9310344827586, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=167, Percent_Identity=39.5209580838323, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6321649, Length=141, Percent_Identity=31.9148936170213, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319281, Length=88, Percent_Identity=38.6363636363636, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI20129375, Length=325, Percent_Identity=40.3076923076923, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24585318, Length=299, Percent_Identity=38.7959866220736, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24640873, Length=148, Percent_Identity=34.4594594594595, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24640877, Length=148, Percent_Identity=34.4594594594595, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24640875, Length=148, Percent_Identity=34.4594594594595, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17981711, Length=87, Percent_Identity=40.2298850574713, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356473, Length=88, Percent_Identity=38.6363636363636, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_CHLAA (A9WK62)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001634902.1
- ProteinModelPortal:   A9WK62
- SMR:   A9WK62
- GeneID:   5828389
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_1285
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12297
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 47655; Mature: 47655

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTETDFFDQATIVVRAGNGGNGAATFRREKYVPRGGPNGGDGGRGGHVYLIADPEYNTL
CCCCCCCCCCEEEEEEECCCCCCCEEEHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCE
LHFRYQRKFVAENGGHGGKNAMHGRNGTDVYVPVPPGTVVRATIDGVTYSVDLARPGQRL
EEEEEHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCEEEEEECCCCCHHH
LAARGGRGGLGNIHFATSTRQAPRLAELGEPGQELTLELELKMLADVGLVGFPNAGKSTL
HHHCCCCCCCCCEEEECCCCCCCCHHHHCCCCCCEEEEEEEEEHHCCCEEECCCCCHHHH
LSVISAARPKIAAYPFTTLTPNLGIVEVGLQRFVVADIPGLIEGAHAGVGLGHDFLRHVE
HHHHHHCCCCEEECCCCCCCCCCCEEHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHH
RTRLLIHIIDAAGVDGRYPWDDYEQINTELRLYQPELAQRKQVVALNKADLPAAQENLPI
HHEEEEEEEECCCCCCCCCCCHHHHHCCEEEEECCHHHCCCEEEEECCCCCCCCCCCCHH
LRERLPVAPEDLFVISAATGEGIEPLLRRVADLLRADPPPQRDPVDPDEPPLQWPLPEVD
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
ENAFTIEREGEAFRVRGIKIERLIAMSNLDQDEALDRIQRVLEASGINEALIAAGVQDGD
CCEEEEEECCCEEEEECEEEEEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCC
LVRIGRAELVWDDSGQHAL
EEEECCEEEEECCCCCCCC
>Mature Secondary Structure
MKTETDFFDQATIVVRAGNGGNGAATFRREKYVPRGGPNGGDGGRGGHVYLIADPEYNTL
CCCCCCCCCCEEEEEEECCCCCCCEEEHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCE
LHFRYQRKFVAENGGHGGKNAMHGRNGTDVYVPVPPGTVVRATIDGVTYSVDLARPGQRL
EEEEEHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCEEEEEECCCCCHHH
LAARGGRGGLGNIHFATSTRQAPRLAELGEPGQELTLELELKMLADVGLVGFPNAGKSTL
HHHCCCCCCCCCEEEECCCCCCCCHHHHCCCCCCEEEEEEEEEHHCCCEEECCCCCHHHH
LSVISAARPKIAAYPFTTLTPNLGIVEVGLQRFVVADIPGLIEGAHAGVGLGHDFLRHVE
HHHHHHCCCCEEECCCCCCCCCCCEEHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHH
RTRLLIHIIDAAGVDGRYPWDDYEQINTELRLYQPELAQRKQVVALNKADLPAAQENLPI
HHEEEEEEEECCCCCCCCCCCHHHHHCCEEEEECCHHHCCCEEEEECCCCCCCCCCCCHH
LRERLPVAPEDLFVISAATGEGIEPLLRRVADLLRADPPPQRDPVDPDEPPLQWPLPEVD
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
ENAFTIEREGEAFRVRGIKIERLIAMSNLDQDEALDRIQRVLEASGINEALIAAGVQDGD
CCEEEEEECCCEEEEECEEEEEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCC
LVRIGRAELVWDDSGQHAL
EEEECCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA