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The map label for this gene is hisC [H]

Identifier: 222524559

GI number: 222524559

Start: 1643670

End: 1644770

Strand: Direct

Name: hisC [H]

Synonym: Chy400_1283

Alternate gene names: 222524559

Gene position: 1643670-1644770 (Clockwise)

Preceding gene: 222524558

Following gene: 222524560

Centisome position: 31.2

GC content: 58.31

Gene sequence:

>1101_bases
GTGCCGATCCGTAAGAAAGCGTTTCTTCAGGCTTTATCGCCAACGCCACCACCTCGCCGATCATCGACCGGTGTCGTCGT
TGCCCGTCTGTCCGCCAATGAAAATCCACTTGGCCCATCACCGCGGGCTATGGCTGCCGTGCAAGAGGCGCTGAGCACGA
TCCACCGTTATCCCGACGCAAGTGGCGTGGCCTTGAAGGAGGCATTGGCCGCTCGCGTCGATCTGCACCCCGACCAGGTG
ATGCTGGGCAATGGTTCAGATGAGCTGATTATGCTTATCTGCCATGCTATGCTCGGCGAGGGTGATGAAGCAGTCCTGGC
GCAGGGATCGTTTATCAGCTATGCCCGCCGGATTCAGGCCCAAGGCGCGATTGCCCGTCAGGTTCCTCTGCGCGAGATGA
CACACGATCTCCCAGCCATGGCTGCCGCGATCACACCGCAAACCCGCCTTATCTTTGTATGTAATCCCAACAATCCGACC
GGTACCACGGTCGGCGCCGCTGAATTGATGGCATTTCTCGAACAGGTACCGCCTGATGTACTGGTCGTTGTTGATGAAGC
CTATCTGGAATTTGTGACGCGCCCGGATTTTCCCGATCTGCTGCCGTTGTTGCGCGACGGACGCGATAACCTGCTGATTG
TGCGCACCTTCGCCAAGATTCACGGTCTGGCCGGTTTACGGCTGGGCTACGCTTTCGGCAACGCCGATCTGATAGCGTAC
CTGGAACGGGCGCGTCCGGTCTTCAACGTGAACGTTCTGGCCCAGATTGCCGGCCTTGCCGCCCTTGACGACGTTGACCA
TCTCGAACGCTCTCTGGCCCATGCCGCTGCCAGCCGGGCATTCCTCACCGACCATCTACGGGCTATGGGGATGACGGTGA
TCCCCGGTGAAACCAATTTTGTCGTCGCCGCAATTGCCGATGATACTGCAGTGGCAGCAGAGCTTGCTCGCCGCGGGGTG
TTGGTCACACCGCTGAGTGGGTGGGGCTTACCGGGCTGGATGCGGATTTCGTTTGGCACTGCGGAAGAGAACCGTGTGTT
TATTGAGGTACTACGCAATTTGATGTCAAAAGGTACCGTGGCAACAGCAACAATATCGTAG

Upstream 100 bases:

>100_bases
CAGGGCAGCACGTTTATGGTGCTGTTACCGGTTGAACGAATGCAGCGTTCACGTACTGAGCGGATGAATCGCTCTTTTGA
ACTGTCAGCGGAGATTTGAT

Downstream 100 bases:

>100_bases
CACCCAAGGATGTAGATATGGGCGACTCACCGAACCCAACATTTTGTGCGAGCTGTGGACATAAGCTCACCCCGGAAGAT
CGCTTTTGTCCAGAGTGTGG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MPIRKKAFLQALSPTPPPRRSSTGVVVARLSANENPLGPSPRAMAAVQEALSTIHRYPDASGVALKEALAARVDLHPDQV
MLGNGSDELIMLICHAMLGEGDEAVLAQGSFISYARRIQAQGAIARQVPLREMTHDLPAMAAAITPQTRLIFVCNPNNPT
GTTVGAAELMAFLEQVPPDVLVVVDEAYLEFVTRPDFPDLLPLLRDGRDNLLIVRTFAKIHGLAGLRLGYAFGNADLIAY
LERARPVFNVNVLAQIAGLAALDDVDHLERSLAHAAASRAFLTDHLRAMGMTVIPGETNFVVAAIADDTAVAAELARRGV
LVTPLSGWGLPGWMRISFGTAEENRVFIEVLRNLMSKGTVATATIS

Sequences:

>Translated_366_residues
MPIRKKAFLQALSPTPPPRRSSTGVVVARLSANENPLGPSPRAMAAVQEALSTIHRYPDASGVALKEALAARVDLHPDQV
MLGNGSDELIMLICHAMLGEGDEAVLAQGSFISYARRIQAQGAIARQVPLREMTHDLPAMAAAITPQTRLIFVCNPNNPT
GTTVGAAELMAFLEQVPPDVLVVVDEAYLEFVTRPDFPDLLPLLRDGRDNLLIVRTFAKIHGLAGLRLGYAFGNADLIAY
LERARPVFNVNVLAQIAGLAALDDVDHLERSLAHAAASRAFLTDHLRAMGMTVIPGETNFVVAAIADDTAVAAELARRGV
LVTPLSGWGLPGWMRISFGTAEENRVFIEVLRNLMSKGTVATATIS
>Mature_365_residues
PIRKKAFLQALSPTPPPRRSSTGVVVARLSANENPLGPSPRAMAAVQEALSTIHRYPDASGVALKEALAARVDLHPDQVM
LGNGSDELIMLICHAMLGEGDEAVLAQGSFISYARRIQAQGAIARQVPLREMTHDLPAMAAAITPQTRLIFVCNPNNPTG
TTVGAAELMAFLEQVPPDVLVVVDEAYLEFVTRPDFPDLLPLLRDGRDNLLIVRTFAKIHGLAGLRLGYAFGNADLIAYL
ERARPVFNVNVLAQIAGLAALDDVDHLERSLAHAAASRAFLTDHLRAMGMTVIPGETNFVVAAIADDTAVAAELARRGVL
VTPLSGWGLPGWMRISFGTAEENRVFIEVLRNLMSKGTVATATIS

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=330, Percent_Identity=28.7878787878788, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788722, Length=353, Percent_Identity=25.7790368271955, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786816, Length=302, Percent_Identity=25.4966887417219, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788627, Length=224, Percent_Identity=26.7857142857143, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322075, Length=361, Percent_Identity=28.2548476454294, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39231; Mature: 39100

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRKKAFLQALSPTPPPRRSSTGVVVARLSANENPLGPSPRAMAAVQEALSTIHRYPDA
CCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
SGVALKEALAARVDLHPDQVMLGNGSDELIMLICHAMLGEGDEAVLAQGSFISYARRIQA
CCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH
QGAIARQVPLREMTHDLPAMAAAITPQTRLIFVCNPNNPTGTTVGAAELMAFLEQVPPDV
CCCHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCE
LVVVDEAYLEFVTRPDFPDLLPLLRDGRDNLLIVRTFAKIHGLAGLRLGYAFGNADLIAY
EEEEEHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEHHHHHCCCHHEEEEEECCHHHHHH
LERARPVFNVNVLAQIAGLAALDDVDHLERSLAHAAASRAFLTDHLRAMGMTVIPGETNF
HHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCE
VVAAIADDTAVAAELARRGVLVTPLSGWGLPGWMRISFGTAEENRVFIEVLRNLMSKGTV
EEEEECCCHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCE
ATATIS
EEEEEC
>Mature Secondary Structure 
PIRKKAFLQALSPTPPPRRSSTGVVVARLSANENPLGPSPRAMAAVQEALSTIHRYPDA
CCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
SGVALKEALAARVDLHPDQVMLGNGSDELIMLICHAMLGEGDEAVLAQGSFISYARRIQA
CCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH
QGAIARQVPLREMTHDLPAMAAAITPQTRLIFVCNPNNPTGTTVGAAELMAFLEQVPPDV
CCCHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCE
LVVVDEAYLEFVTRPDFPDLLPLLRDGRDNLLIVRTFAKIHGLAGLRLGYAFGNADLIAY
EEEEEHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEHHHHHCCCHHEEEEEECCHHHHHH
LERARPVFNVNVLAQIAGLAALDDVDHLERSLAHAAASRAFLTDHLRAMGMTVIPGETNF
HHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCE
VVAAIADDTAVAAELARRGVLVTPLSGWGLPGWMRISFGTAEENRVFIEVLRNLMSKGTV
EEEEECCCHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCE
ATATIS
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA