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The map label for this gene is yycG [H]

Identifier: 222524558

GI number: 222524558

Start: 1641440

End: 1643668

Strand: Direct

Name: yycG [H]

Synonym: Chy400_1282

Alternate gene names: 222524558

Gene position: 1641440-1643668 (Clockwise)

Preceding gene: 222524557

Following gene: 222524559

Centisome position: 31.15

GC content: 56.75

Gene sequence:

>2229_bases
ATGACTGAACACCAGCCAGAGCTTAGCGCATCTGATCAGATGATAGAGCGAGCAGTGTCAGGTGAGGGTATCCAGCACTG
GCTCAAGATCAGTGCGGCCTGGCTGGCCTTGCAAGAACCAGAACGCCTCTTTCCGACCCTGGTCTCCAGTTTTGCCGAAC
ATTTACCGGCTGTGCGCACCGTCATTCTCTGGCTCGTTACCACGGGCGGCTTGCAACCGGTAGCTCACGCCGGGTTCACG
ATACCGTCTGCAATCAGTGAACACTGGTTGCGGGTCAGATTGCGACCTGGAGAAGGAGCCGCCGGGCTGGCCTGGCAGCG
TGAGACGGTGATCCAACAACACGGCGAACACGGCTATCGTGAATTGCAGGGTATTGCATCCCCCCAGGCACAGACGGTCT
TTCAGGCAATCGGTGATCTCTTACCGCGCAGCCTGCTGGTGACCGCTATCCCACTGCGCGCAGGGCACACGCTGGTAGGG
GTGCTGGAGCTGGCCAGCAATGCCAATGAGCCACTTGGTATAGAGATGGCCGATTTCGAGGTTATCGCCGGTATCGTTGC
CGCAGCCATTCGCAACGCCCAATTGTACGATGAACTCCGGCGCAGCCACCAACGGCTGAAAGCGTTTGATGCAGTTGTAA
CGTCGATCAGCACTGCTGCCGATCTGCCCGATCTGGTGCAGAGTGTTTTGACCGTTGTCCTCGAATTGACCCCTGCCCAG
AGTGGTGCGCTCCTGATCTTCGATCCGGCCCAGGAACGTCTACAGGTCAGTGCCTGGTGTAACATTGACCTGACTGCTCT
TGCCTGTTTCGACCAGGTGTCGGTTGATGCGACTCCCTGTGCAGAAGTTGTTCGTTACGGCCAGCCGGCATTTCGGCCAC
TGCTCAGCGAGCGTGGCGAATCGGCGTTGATCGAGGCCGGTATGGCGGCGGCGGCCTATCTACCGCTGCTCGCCGGCGGT
ACTGTGACCGGTGTGCTGGCGCTGTTCGGCGATATCGAACTCACCAAGGCAATTGACAAAGACATGCTGATGCCGATCTG
TAATCAGGTCGGTTTCGCGATTGCTAACGTGCGGTTGTATGAAGATAGCCAACACGAGCGGAGAAAATTCCATACGGTGA
TCGAGTCGATTGCCGAGGGGGTGTTACTGTGTGATCGTTACGGTCGTTTAACCCTGGCCAACCAGGCTGCCCACGATCTT
CTCTCCTGCGCAACGCTGAGCTTCGAGACACCCCTGGCAACTGTTCCTGATCTGTACGATCTGCGCGATCTCGATGGGAA
TGCTCTGACGCCTGATGATTTACCATTTACCCGCGCTTTGCGTGGCGAAACGTTTTACGATTATCGGGTGATGCGACGCC
TGCCCGATAACAGTGAGCGCTTCTTCAGCTTCAGTGGCGCCCCAGCGGTTAACGAACAGGGTGAAGTTGAAGGCGCAGTG
ATTACGTTCCGCGACATTACTGCAACCCAAAAGGTGCAGCGGGCAAAGGATGAATTTCTGGCCGTAGCCGCCCATGAATT
ACGCAGCCCGCTGGCAGCGGTACGCAGTTATGCCGATCTTTTGTTGCGACGAGAACAACAGCGGGAGGGGGATCATCGCG
ATTTGCACGGCTTGACGATCCTCTCGCAACAGGTGGCGCATATGCTCCGCCTGGTGGATAATCTCCTCGATGTTTCGCGC
CTTGATGCCGGCCAGTTTGATTTGCAATATCAACAGGTCAATCTCGTCGGGCTGGCTCAGCAGGTGATCGATCAACAACG
ACCAAACGCCGGTCAACGCGATTTACTGCTTGAGGCCGAGTCGGCGGAATTGATGGTAACCTGCGATGCGATGCGTATCC
GGCAGGTACTGACAAATCTGATCAGCAACGCTATCAAGTACAGTCCACCCGACAGTGTGATCAGCGTGCGTCTCCGCAGC
GCGACTCTGCTAAACAACAATGCACCTGCGGTGCTGATCAGTGTCAGTGATCAGGGGCCGGGCATTCCCCCTGAAGAGCA
GGAGCGCGTGTTTCAGCGCTACTATCGTGCACCTGGCCGCCGGGCAGAGGGGTTGGGGTTGGGCTTGTATCTAAGCCGTG
AGATTGTTCAGTTGCACGGTGGTCAGATTTGGATTGAGAGTCGCGAGGGTCAGGGCAGCACGTTTATGGTGCTGTTACCG
GTTGAACGAATGCAGCGTTCACGTACTGAGCGGATGAATCGCTCTTTTGAACTGTCAGCGGAGATTTGA

Upstream 100 bases:

>100_bases
ATATTCGGCAGGCCCGCGAATTGTTGGGATTCAACCCGCAAGTACCGTTAGCGGAAGGTATCAACCGCGCCGTGGCCTGG
TCGCACGGAGAGTTGCTACG

Downstream 100 bases:

>100_bases
TGTGCCGATCCGTAAGAAAGCGTTTCTTCAGGCTTTATCGCCAACGCCACCACCTCGCCGATCATCGACCGGTGTCGTCG
TTGCCCGTCTGTCCGCCAAT

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 742; Mature: 741

Protein sequence:

>742_residues
MTEHQPELSASDQMIERAVSGEGIQHWLKISAAWLALQEPERLFPTLVSSFAEHLPAVRTVILWLVTTGGLQPVAHAGFT
IPSAISEHWLRVRLRPGEGAAGLAWQRETVIQQHGEHGYRELQGIASPQAQTVFQAIGDLLPRSLLVTAIPLRAGHTLVG
VLELASNANEPLGIEMADFEVIAGIVAAAIRNAQLYDELRRSHQRLKAFDAVVTSISTAADLPDLVQSVLTVVLELTPAQ
SGALLIFDPAQERLQVSAWCNIDLTALACFDQVSVDATPCAEVVRYGQPAFRPLLSERGESALIEAGMAAAAYLPLLAGG
TVTGVLALFGDIELTKAIDKDMLMPICNQVGFAIANVRLYEDSQHERRKFHTVIESIAEGVLLCDRYGRLTLANQAAHDL
LSCATLSFETPLATVPDLYDLRDLDGNALTPDDLPFTRALRGETFYDYRVMRRLPDNSERFFSFSGAPAVNEQGEVEGAV
ITFRDITATQKVQRAKDEFLAVAAHELRSPLAAVRSYADLLLRREQQREGDHRDLHGLTILSQQVAHMLRLVDNLLDVSR
LDAGQFDLQYQQVNLVGLAQQVIDQQRPNAGQRDLLLEAESAELMVTCDAMRIRQVLTNLISNAIKYSPPDSVISVRLRS
ATLLNNNAPAVLISVSDQGPGIPPEEQERVFQRYYRAPGRRAEGLGLGLYLSREIVQLHGGQIWIESREGQGSTFMVLLP
VERMQRSRTERMNRSFELSAEI

Sequences:

>Translated_742_residues
MTEHQPELSASDQMIERAVSGEGIQHWLKISAAWLALQEPERLFPTLVSSFAEHLPAVRTVILWLVTTGGLQPVAHAGFT
IPSAISEHWLRVRLRPGEGAAGLAWQRETVIQQHGEHGYRELQGIASPQAQTVFQAIGDLLPRSLLVTAIPLRAGHTLVG
VLELASNANEPLGIEMADFEVIAGIVAAAIRNAQLYDELRRSHQRLKAFDAVVTSISTAADLPDLVQSVLTVVLELTPAQ
SGALLIFDPAQERLQVSAWCNIDLTALACFDQVSVDATPCAEVVRYGQPAFRPLLSERGESALIEAGMAAAAYLPLLAGG
TVTGVLALFGDIELTKAIDKDMLMPICNQVGFAIANVRLYEDSQHERRKFHTVIESIAEGVLLCDRYGRLTLANQAAHDL
LSCATLSFETPLATVPDLYDLRDLDGNALTPDDLPFTRALRGETFYDYRVMRRLPDNSERFFSFSGAPAVNEQGEVEGAV
ITFRDITATQKVQRAKDEFLAVAAHELRSPLAAVRSYADLLLRREQQREGDHRDLHGLTILSQQVAHMLRLVDNLLDVSR
LDAGQFDLQYQQVNLVGLAQQVIDQQRPNAGQRDLLLEAESAELMVTCDAMRIRQVLTNLISNAIKYSPPDSVISVRLRS
ATLLNNNAPAVLISVSDQGPGIPPEEQERVFQRYYRAPGRRAEGLGLGLYLSREIVQLHGGQIWIESREGQGSTFMVLLP
VERMQRSRTERMNRSFELSAEI
>Mature_741_residues
TEHQPELSASDQMIERAVSGEGIQHWLKISAAWLALQEPERLFPTLVSSFAEHLPAVRTVILWLVTTGGLQPVAHAGFTI
PSAISEHWLRVRLRPGEGAAGLAWQRETVIQQHGEHGYRELQGIASPQAQTVFQAIGDLLPRSLLVTAIPLRAGHTLVGV
LELASNANEPLGIEMADFEVIAGIVAAAIRNAQLYDELRRSHQRLKAFDAVVTSISTAADLPDLVQSVLTVVLELTPAQS
GALLIFDPAQERLQVSAWCNIDLTALACFDQVSVDATPCAEVVRYGQPAFRPLLSERGESALIEAGMAAAAYLPLLAGGT
VTGVLALFGDIELTKAIDKDMLMPICNQVGFAIANVRLYEDSQHERRKFHTVIESIAEGVLLCDRYGRLTLANQAAHDLL
SCATLSFETPLATVPDLYDLRDLDGNALTPDDLPFTRALRGETFYDYRVMRRLPDNSERFFSFSGAPAVNEQGEVEGAVI
TFRDITATQKVQRAKDEFLAVAAHELRSPLAAVRSYADLLLRREQQREGDHRDLHGLTILSQQVAHMLRLVDNLLDVSRL
DAGQFDLQYQQVNLVGLAQQVIDQQRPNAGQRDLLLEAESAELMVTCDAMRIRQVLTNLISNAIKYSPPDSVISVRLRSA
TLLNNNAPAVLISVSDQGPGIPPEEQERVFQRYYRAPGRRAEGLGLGLYLSREIVQLHGGQIWIESREGQGSTFMVLLPV
ERMQRSRTERMNRSFELSAEI

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=248, Percent_Identity=30.241935483871, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788549, Length=377, Percent_Identity=27.8514588859416, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1786600, Length=430, Percent_Identity=25.3488372093023, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI48994928, Length=295, Percent_Identity=27.4576271186441, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1789149, Length=252, Percent_Identity=30.952380952381, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=26.25, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=28.82096069869, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786783, Length=251, Percent_Identity=28.2868525896414, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=30.8035714285714, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790551, Length=250, Percent_Identity=31.2, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI87081816, Length=257, Percent_Identity=29.9610894941634, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788393, Length=252, Percent_Identity=28.968253968254, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1789403, Length=263, Percent_Identity=30.0380228136882, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1790861, Length=222, Percent_Identity=29.2792792792793, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788279, Length=199, Percent_Identity=26.1306532663317, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=302, Percent_Identity=25.4966887417219, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=371, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=25.3112033195021, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=237, Percent_Identity=27.8481012658228, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81805; Mature: 81674

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHQPELSASDQMIERAVSGEGIQHWLKISAAWLALQEPERLFPTLVSSFAEHLPAVRT
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VILWLVTTGGLQPVAHAGFTIPSAISEHWLRVRLRPGEGAAGLAWQRETVIQQHGEHGYR
HHHHHHHCCCCCHHHHCCCCCHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCHHHH
ELQGIASPQAQTVFQAIGDLLPRSLLVTAIPLRAGHTLVGVLELASNANEPLGIEMADFE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHH
VIAGIVAAAIRNAQLYDELRRSHQRLKAFDAVVTSISTAADLPDLVQSVLTVVLELTPAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
SGALLIFDPAQERLQVSAWCNIDLTALACFDQVSVDATPCAEVVRYGQPAFRPLLSERGE
CCEEEEECCCHHHEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHCCCC
SALIEAGMAAAAYLPLLAGGTVTGVLALFGDIELTKAIDKDMLMPICNQVGFAIANVRLY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
EDSQHERRKFHTVIESIAEGVLLCDRYGRLTLANQAAHDLLSCATLSFETPLATVPDLYD
CCCHHHHHHHHHHHHHHHHHHEEHHCCCCEEECHHHHHHHHHHHHHCCCCCCCCCCCCHH
LRDLDGNALTPDDLPFTRALRGETFYDYRVMRRLPDNSERFFSFSGAPAVNEQGEVEGAV
HHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCHHEEEECCCCCCCCCCCCCEEE
ITFRDITATQKVQRAKDEFLAVAAHELRSPLAAVRSYADLLLRREQQREGDHRDLHGLTI
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LSQQVAHMLRLVDNLLDVSRLDAGQFDLQYQQVNLVGLAQQVIDQQRPNAGQRDLLLEAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
SAELMVTCDAMRIRQVLTNLISNAIKYSPPDSVISVRLRSATLLNNNAPAVLISVSDQGP
CCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEEHHHEEECCCCCEEEEEECCCCC
GIPPEEQERVFQRYYRAPGRRAEGLGLGLYLSREIVQLHGGQIWIESREGQGSTFMVLLP
CCCCHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEC
VERMQRSRTERMNRSFELSAEI
HHHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure 
TEHQPELSASDQMIERAVSGEGIQHWLKISAAWLALQEPERLFPTLVSSFAEHLPAVRT
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VILWLVTTGGLQPVAHAGFTIPSAISEHWLRVRLRPGEGAAGLAWQRETVIQQHGEHGYR
HHHHHHHCCCCCHHHHCCCCCHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCHHHH
ELQGIASPQAQTVFQAIGDLLPRSLLVTAIPLRAGHTLVGVLELASNANEPLGIEMADFE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHH
VIAGIVAAAIRNAQLYDELRRSHQRLKAFDAVVTSISTAADLPDLVQSVLTVVLELTPAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
SGALLIFDPAQERLQVSAWCNIDLTALACFDQVSVDATPCAEVVRYGQPAFRPLLSERGE
CCEEEEECCCHHHEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHCCCC
SALIEAGMAAAAYLPLLAGGTVTGVLALFGDIELTKAIDKDMLMPICNQVGFAIANVRLY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
EDSQHERRKFHTVIESIAEGVLLCDRYGRLTLANQAAHDLLSCATLSFETPLATVPDLYD
CCCHHHHHHHHHHHHHHHHHHEEHHCCCCEEECHHHHHHHHHHHHHCCCCCCCCCCCCHH
LRDLDGNALTPDDLPFTRALRGETFYDYRVMRRLPDNSERFFSFSGAPAVNEQGEVEGAV
HHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCHHEEEECCCCCCCCCCCCCEEE
ITFRDITATQKVQRAKDEFLAVAAHELRSPLAAVRSYADLLLRREQQREGDHRDLHGLTI
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LSQQVAHMLRLVDNLLDVSRLDAGQFDLQYQQVNLVGLAQQVIDQQRPNAGQRDLLLEAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
SAELMVTCDAMRIRQVLTNLISNAIKYSPPDSVISVRLRSATLLNNNAPAVLISVSDQGP
CCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEEHHHEEECCCCCEEEEEECCCCC
GIPPEEQERVFQRYYRAPGRRAEGLGLGLYLSREIVQLHGGQIWIESREGQGSTFMVLLP
CCCCHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEC
VERMQRSRTERMNRSFELSAEI
HHHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]