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The map label for this gene is aidB [H]

Identifier: 222524149

GI number: 222524149

Start: 1094194

End: 1095651

Strand: Reverse

Name: aidB [H]

Synonym: Chy400_0865

Alternate gene names: 222524149

Gene position: 1095651-1094194 (Counterclockwise)

Preceding gene: 222524150

Following gene: 222524148

Centisome position: 20.79

GC content: 59.74

Gene sequence:

>1458_bases
ATGGAACAGCATATCTTTTCGCCGCTGGCGTTTTTGCGCCACCAGTTGGCCGATCTCGCTCAACCAGACTATCTGGAAGC
GTATCAGGCATGGTGGGAACACGAGGGGAAGCCGGTCTCGGCGGCAATTGATCGGGCCGGGACACCCTGGCTGCGAATGT
TTGATCGCCAGGGGCAACGGGTTGATGAGATTCTCTACCCCGCTGAATACTGGCGTATGGTGCGGCAGGGCTACCAAAGC
GGTGTGATCTGGCGGGTCTTTACCGAAACCTCACTCGTGCCGCACTACCTGTTGGGCTATCTTACCGCTTTCTACGATGC
CGGTCTCTACTGCCCGTATACCGTGTCACTTTCAACCGCGGTGCCGCTGGCTAAGTATGGGACGGAAGCAGTGAAAGCCC
AGTTTTTGCCGTTGCTGCTGCGCCAGGACGCAACGGTCTGGCAGGGGGCAACCTGGATGACCGAGATCGGTGGCGGCTCT
GATCTGGGGACGACCGTAGCGACCATCGCGGTTGCTGAGGATGGCCGCTGGTATCTGAGTGGTGATAAGTATTTTGCCAG
TAATGTCGGTGCCGAACTGGCAGTAGTTGCTGCCCGCTTCGCCACCGGCCCGGCAGATATTCGTGGTCTGGGCCTGTTTC
TCGTCCCCCGCTACCGCGCCGATGGCAGTCTCAACTACACCATTCGCCGCCTGAAAGACAAGATCGGTACGCGCGCGGTA
CCCACCGGTGAAGTAGAATTGCGTCGCAGCGAAGCCTATTTGTTGGGGCGGGCGGAATGGGGTATCTACCTCATTCTGGA
GACCCTGAACCTCTCGCGGGTGGCAAACAGTGTGGGTAGTGTCGCGCTGGCCCAGCGTGCGCTGGCCGAAGCAGTGAGTT
TTGCGCACCAGCGTCGGGCTTTCGGTAAGCCGATAGCTGCCCACCCCTTGCTCAAACGTCAGATTGAGGAACGCATTGTC
GAACTGGAAGCTGCCTTTGCGCTGGCCTGGGAAGCGGTTTGCCTGCTCGAACAAGTCTGGCATGTGACACCACCCTATCC
AGAACAGTACCATCTCTTTCGTTTGCTTGCGCATCTCGCCAAGTACTGGACGGCTGAGTTTGCGGTGCAGACGGCAAAGT
GGGGGATGGAGGTTCACGGCGGGATTGGGACGCTCGCCGAGTACAATGCCGAGCGCTGGTTGCGCGATGCAATGATTCTG
CCGATCTGGGAGGGAACGCCACACCGCCAGATTCTGGACGGCCTGGAAGTGATGGAGCGCAAAGGGGCGCATCGGATGCT
CTTGCACTATCTGGCTGCTGATGCCCCAACGCAGGCTTTAACCGACATGCAGCATCGGATCGAGGCCCATCTCGCACTTC
CCCAGGAAGAGAAAGAAGCCGGGGCCGAGAGTCTCTTCCGTGATCTGGCCTTGCTGACGGCACACACCCTGCGCGCACGC
CGGCTGGCCAGGCGGTGA

Upstream 100 bases:

>100_bases
GCGCAGACAATCACATCATCACTCTGTGCCCTCGGTGTCTCTGTGGTGCATCACCCATCGCACTGCCAGATTTGCTATAA
TCCCAGCAGAGGTGATGACT

Downstream 100 bases:

>100_bases
TGGCGGCGTGCGCTGGTGATCAGGTTATGGTTGCCCTTCCTGTTGCCCATCTGCAGCGGGTTGTGTGTTCACGCGCCGGC
GAACACCCTTGACGGGCCTC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MEQHIFSPLAFLRHQLADLAQPDYLEAYQAWWEHEGKPVSAAIDRAGTPWLRMFDRQGQRVDEILYPAEYWRMVRQGYQS
GVIWRVFTETSLVPHYLLGYLTAFYDAGLYCPYTVSLSTAVPLAKYGTEAVKAQFLPLLLRQDATVWQGATWMTEIGGGS
DLGTTVATIAVAEDGRWYLSGDKYFASNVGAELAVVAARFATGPADIRGLGLFLVPRYRADGSLNYTIRRLKDKIGTRAV
PTGEVELRRSEAYLLGRAEWGIYLILETLNLSRVANSVGSVALAQRALAEAVSFAHQRRAFGKPIAAHPLLKRQIEERIV
ELEAAFALAWEAVCLLEQVWHVTPPYPEQYHLFRLLAHLAKYWTAEFAVQTAKWGMEVHGGIGTLAEYNAERWLRDAMIL
PIWEGTPHRQILDGLEVMERKGAHRMLLHYLAADAPTQALTDMQHRIEAHLALPQEEKEAGAESLFRDLALLTAHTLRAR
RLARR

Sequences:

>Translated_485_residues
MEQHIFSPLAFLRHQLADLAQPDYLEAYQAWWEHEGKPVSAAIDRAGTPWLRMFDRQGQRVDEILYPAEYWRMVRQGYQS
GVIWRVFTETSLVPHYLLGYLTAFYDAGLYCPYTVSLSTAVPLAKYGTEAVKAQFLPLLLRQDATVWQGATWMTEIGGGS
DLGTTVATIAVAEDGRWYLSGDKYFASNVGAELAVVAARFATGPADIRGLGLFLVPRYRADGSLNYTIRRLKDKIGTRAV
PTGEVELRRSEAYLLGRAEWGIYLILETLNLSRVANSVGSVALAQRALAEAVSFAHQRRAFGKPIAAHPLLKRQIEERIV
ELEAAFALAWEAVCLLEQVWHVTPPYPEQYHLFRLLAHLAKYWTAEFAVQTAKWGMEVHGGIGTLAEYNAERWLRDAMIL
PIWEGTPHRQILDGLEVMERKGAHRMLLHYLAADAPTQALTDMQHRIEAHLALPQEEKEAGAESLFRDLALLTAHTLRAR
RLARR
>Mature_485_residues
MEQHIFSPLAFLRHQLADLAQPDYLEAYQAWWEHEGKPVSAAIDRAGTPWLRMFDRQGQRVDEILYPAEYWRMVRQGYQS
GVIWRVFTETSLVPHYLLGYLTAFYDAGLYCPYTVSLSTAVPLAKYGTEAVKAQFLPLLLRQDATVWQGATWMTEIGGGS
DLGTTVATIAVAEDGRWYLSGDKYFASNVGAELAVVAARFATGPADIRGLGLFLVPRYRADGSLNYTIRRLKDKIGTRAV
PTGEVELRRSEAYLLGRAEWGIYLILETLNLSRVANSVGSVALAQRALAEAVSFAHQRRAFGKPIAAHPLLKRQIEERIV
ELEAAFALAWEAVCLLEQVWHVTPPYPEQYHLFRLLAHLAKYWTAEFAVQTAKWGMEVHGGIGTLAEYNAERWLRDAMIL
PIWEGTPHRQILDGLEVMERKGAHRMLLHYLAADAPTQALTDMQHRIEAHLALPQEEKEAGAESLFRDLALLTAHTLRAR
RLARR

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=324, Percent_Identity=27.4691358024691, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI226958412, Length=290, Percent_Identity=27.5862068965517, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI226958414, Length=290, Percent_Identity=27.5862068965517, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI4501857, Length=289, Percent_Identity=28.0276816608997, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4501859, Length=308, Percent_Identity=28.8961038961039, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI21361497, Length=298, Percent_Identity=28.1879194630872, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI187960098, Length=300, Percent_Identity=27, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4557231, Length=300, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI7656849, Length=289, Percent_Identity=23.5294117647059, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4557235, Length=292, Percent_Identity=26.7123287671233, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI76496475, Length=292, Percent_Identity=26.7123287671233, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082384, Length=427, Percent_Identity=29.03981264637, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI87081958, Length=277, Percent_Identity=25.2707581227437, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI86563381, Length=398, Percent_Identity=29.8994974874372, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI86563383, Length=398, Percent_Identity=29.8994974874372, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17506239, Length=303, Percent_Identity=29.3729372937294, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=336, Percent_Identity=25.297619047619, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=380, Percent_Identity=26.0526315789474, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=408, Percent_Identity=25.7352941176471, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=288, Percent_Identity=24.6527777777778, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=358, Percent_Identity=23.7430167597765, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32563615, Length=224, Percent_Identity=27.6785714285714, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=290, Percent_Identity=23.448275862069, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71990804, Length=216, Percent_Identity=26.3888888888889, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356377, Length=297, Percent_Identity=28.956228956229, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24666513, Length=294, Percent_Identity=28.2312925170068, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24660351, Length=387, Percent_Identity=26.8733850129199, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=25.9459459459459, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21355753, Length=291, Percent_Identity=27.1477663230241, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: 1.3.99.3

Molecular weight: Translated: 54706; Mature: 54706

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQHIFSPLAFLRHQLADLAQPDYLEAYQAWWEHEGKPVSAAIDRAGTPWLRMFDRQGQR
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHCCCH
VDEILYPAEYWRMVRQGYQSGVIWRVFTETSLVPHYLLGYLTAFYDAGLYCPYTVSLSTA
HHHHHCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHC
VPLAKYGTEAVKAQFLPLLLRQDATVWQGATWMTEIGGGSDLGTTVATIAVAEDGRWYLS
CCHHHHCHHHHHHHHHHHHHHCCCCHHCCCCHHHCCCCCCCCCHHEEEEEEECCCCEEEC
GDKYFASNVGAELAVVAARFATGPADIRGLGLFLVPRYRADGSLNYTIRRLKDKIGTRAV
CCEEEHHCCCHHHHHHHHHHCCCCCHHCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCC
PTGEVELRRSEAYLLGRAEWGIYLILETLNLSRVANSVGSVALAQRALAEAVSFAHQRRA
CCCCEEEEECCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGKPIAAHPLLKRQIEERIVELEAAFALAWEAVCLLEQVWHVTPPYPEQYHLFRLLAHLA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KYWTAEFAVQTAKWGMEVHGGIGTLAEYNAERWLRDAMILPIWEGTPHRQILDGLEVMER
HHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHH
KGAHRMLLHYLAADAPTQALTDMQHRIEAHLALPQEEKEAGAESLFRDLALLTAHTLRAR
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLARR
HHHCC
>Mature Secondary Structure
MEQHIFSPLAFLRHQLADLAQPDYLEAYQAWWEHEGKPVSAAIDRAGTPWLRMFDRQGQR
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHCCCH
VDEILYPAEYWRMVRQGYQSGVIWRVFTETSLVPHYLLGYLTAFYDAGLYCPYTVSLSTA
HHHHHCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHC
VPLAKYGTEAVKAQFLPLLLRQDATVWQGATWMTEIGGGSDLGTTVATIAVAEDGRWYLS
CCHHHHCHHHHHHHHHHHHHHCCCCHHCCCCHHHCCCCCCCCCHHEEEEEEECCCCEEEC
GDKYFASNVGAELAVVAARFATGPADIRGLGLFLVPRYRADGSLNYTIRRLKDKIGTRAV
CCEEEHHCCCHHHHHHHHHHCCCCCHHCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCC
PTGEVELRRSEAYLLGRAEWGIYLILETLNLSRVANSVGSVALAQRALAEAVSFAHQRRA
CCCCEEEEECCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGKPIAAHPLLKRQIEERIVELEAAFALAWEAVCLLEQVWHVTPPYPEQYHLFRLLAHLA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KYWTAEFAVQTAKWGMEVHGGIGTLAEYNAERWLRDAMILPIWEGTPHRQILDGLEVMER
HHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHH
KGAHRMLLHYLAADAPTQALTDMQHRIEAHLALPQEEKEAGAESLFRDLALLTAHTLRAR
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLARR
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]