Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 222524107

GI number: 222524107

Start: 1035543

End: 1036646

Strand: Reverse

Name: mraY

Synonym: Chy400_0823

Alternate gene names: 222524107

Gene position: 1036646-1035543 (Counterclockwise)

Preceding gene: 222524108

Following gene: 222524106

Centisome position: 19.67

GC content: 55.8

Gene sequence:

>1104_bases
GTGAGCGTCCTTCGTGCAGTGCTGGTTCAGGATATGGCGCGTGCCCTCTTGCTTGCTGCGGCAGCGTTTGTGTTGACCCT
GATCATCGGTGGGTGGTGGGTACGCTTTGCGCGCCGGCATAAATTGGGGAAGCGTATCCGACCGGATGGCCCCCAGAGTC
ATCTGGTCAAAGTGGGCACGCCAACCATGGGTGGCATCATGATCGTAAGCACCGTGTTGATCCTGACGATCCTGTTTAAC
CTGGTTGATCGCTGGTCAATGCTGCTGCCTCTGGGCGTGATGGTGAGTTTTGCCGTCCTGGGTGCGATTGACGACTGGCT
GTCGCTGACCGGTTCCCGTTCAAAGACGCACGGCTTTACGGTGCGCTTTAAGTTCTGGATTATGATGGCAGTTGCTTTCG
TGGCCAGTCTGGCGCTCTACCTGCCGCAGCCGTATGGTCTGGAGCACGAAGGTCTCGTTCAGATTCCGTTCGTCGGTGAA
GTGAATATCGGGTTGTGGTTTATTCCGATTGCAGTGCTGATTATCGTCTTTATCTCGAATGCAGTCAATATCACCGACGG
TCTCGATAGCCTGGCTGGTTGGAATCTGACGCTCGCCTTTGGGGCGTATGGCGTGATAACGTTTCTCGCCGAGCCGCGCC
TGACCAATCTGATGGCCTTCTGTTTCACCGTAGTGGGTGCCTGCGCTGCCTTTCTCTGGTATAACGCCTATCCGGCGCAG
GTGTTTATGGGTGATCTGGGTGCCCTGGCGCTCGGTGCGACCCTGGCTGTGGTGGCATTACAATCGCAGCAGTGGTTACT
CTTACCGGTGATAGGGATCGTGTTTGTGGTGGAAGCGTTATCCACCATGATTCAGACCGGCTATTTCAAATGGACAAAAT
GGCGGTACGGCGAAGGTCGGCGTATCTTCAAGATGGCGCCACTCCATCACCATTTTGAATTGCTCGGCTGGAGTCAACCG
CAAGTGACGCAGCGCTTTGTCTTGATCGGCACCGTGGCCGCAATGGTTGGTATCTCGCTGGCGCTGATTTTTGGCCCCCC
TGCGACAGGGTTACAGGTCGATCAACCGGGGATCATTGTGATTGAAGGTGATGGGAGCCGGTAA

Upstream 100 bases:

>100_bases
CCGGTGACCACCTGCTTATCAAAGGGTCGCGCGGCGTACAGATGGAGACGATTGTTGCCGCCTTGCAGGCTACTACTCGT
AACGACACAGGAGAAATTGC

Downstream 100 bases:

>100_bases
TGATAGCGGTGGCAGGAAAACGGGTGCTCGTCATGGGGCTTGGGGTTCACGGCGGCGGCCTGGGAGTGGCACGCTGGCTC
TTACGCCATGGTGCCGAAGT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSVLRAVLVQDMARALLLAAAAFVLTLIIGGWWVRFARRHKLGKRIRPDGPQSHLVKVGTPTMGGIMIVSTVLILTILFN
LVDRWSMLLPLGVMVSFAVLGAIDDWLSLTGSRSKTHGFTVRFKFWIMMAVAFVASLALYLPQPYGLEHEGLVQIPFVGE
VNIGLWFIPIAVLIIVFISNAVNITDGLDSLAGWNLTLAFGAYGVITFLAEPRLTNLMAFCFTVVGACAAFLWYNAYPAQ
VFMGDLGALALGATLAVVALQSQQWLLLPVIGIVFVVEALSTMIQTGYFKWTKWRYGEGRRIFKMAPLHHHFELLGWSQP
QVTQRFVLIGTVAAMVGISLALIFGPPATGLQVDQPGIIVIEGDGSR

Sequences:

>Translated_367_residues
MSVLRAVLVQDMARALLLAAAAFVLTLIIGGWWVRFARRHKLGKRIRPDGPQSHLVKVGTPTMGGIMIVSTVLILTILFN
LVDRWSMLLPLGVMVSFAVLGAIDDWLSLTGSRSKTHGFTVRFKFWIMMAVAFVASLALYLPQPYGLEHEGLVQIPFVGE
VNIGLWFIPIAVLIIVFISNAVNITDGLDSLAGWNLTLAFGAYGVITFLAEPRLTNLMAFCFTVVGACAAFLWYNAYPAQ
VFMGDLGALALGATLAVVALQSQQWLLLPVIGIVFVVEALSTMIQTGYFKWTKWRYGEGRRIFKMAPLHHHFELLGWSQP
QVTQRFVLIGTVAAMVGISLALIFGPPATGLQVDQPGIIVIEGDGSR
>Mature_366_residues
SVLRAVLVQDMARALLLAAAAFVLTLIIGGWWVRFARRHKLGKRIRPDGPQSHLVKVGTPTMGGIMIVSTVLILTILFNL
VDRWSMLLPLGVMVSFAVLGAIDDWLSLTGSRSKTHGFTVRFKFWIMMAVAFVASLALYLPQPYGLEHEGLVQIPFVGEV
NIGLWFIPIAVLIIVFISNAVNITDGLDSLAGWNLTLAFGAYGVITFLAEPRLTNLMAFCFTVVGACAAFLWYNAYPAQV
FMGDLGALALGATLAVVALQSQQWLLLPVIGIVFVVEALSTMIQTGYFKWTKWRYGEGRRIFKMAPLHHHFELLGWSQPQ
VTQRFVLIGTVAAMVGISLALIFGPPATGLQVDQPGIIVIEGDGSR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=341, Percent_Identity=37.2434017595308, Blast_Score=198, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_CHLAA (A9WG76)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001634386.1
- GeneID:   5824843
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_0759
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 40142; Mature: 40011

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e2856fc)-; HASH(0x1efc5c1c)-; HASH(0x1efc5b08)-; HASH(0x1efc591c)-; HASH(0x1f00e028)-; HASH(0x1fa46178)-; HASH(0x1efc59b8)-; HASH(0x1f7aa254)-; HASH(0x1efc5b98)-; HASH(0x1eeaae28)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLRAVLVQDMARALLLAAAAFVLTLIIGGWWVRFARRHKLGKRIRPDGPQSHLVKVGT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCEEEECC
PTMGGIMIVSTVLILTILFNLVDRWSMLLPLGVMVSFAVLGAIDDWLSLTGSRSKTHGFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
VRFKFWIMMAVAFVASLALYLPQPYGLEHEGLVQIPFVGEVNIGLWFIPIAVLIIVFISN
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECEECCCCCCHHHHHHHHHHHHHHHC
AVNITDGLDSLAGWNLTLAFGAYGVITFLAEPRLTNLMAFCFTVVGACAAFLWYNAYPAQ
CCCCCCCHHHHCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VFMGDLGALALGATLAVVALQSQQWLLLPVIGIVFVVEALSTMIQTGYFKWTKWRYGEGR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCC
RIFKMAPLHHHFELLGWSQPQVTQRFVLIGTVAAMVGISLALIFGPPATGLQVDQPGIIV
EEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEECCCCEEE
IEGDGSR
EECCCCH
>Mature Secondary Structure 
SVLRAVLVQDMARALLLAAAAFVLTLIIGGWWVRFARRHKLGKRIRPDGPQSHLVKVGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCEEEECC
PTMGGIMIVSTVLILTILFNLVDRWSMLLPLGVMVSFAVLGAIDDWLSLTGSRSKTHGFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
VRFKFWIMMAVAFVASLALYLPQPYGLEHEGLVQIPFVGEVNIGLWFIPIAVLIIVFISN
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECEECCCCCCHHHHHHHHHHHHHHHC
AVNITDGLDSLAGWNLTLAFGAYGVITFLAEPRLTNLMAFCFTVVGACAAFLWYNAYPAQ
CCCCCCCHHHHCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VFMGDLGALALGATLAVVALQSQQWLLLPVIGIVFVVEALSTMIQTGYFKWTKWRYGEGR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCC
RIFKMAPLHHHFELLGWSQPQVTQRFVLIGTVAAMVGISLALIFGPPATGLQVDQPGIIV
EEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEECCCCEEE
IEGDGSR
EECCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA