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The map label for this gene is cysC

Identifier: 222524033

GI number: 222524033

Start: 932534

End: 933094

Strand: Reverse

Name: cysC

Synonym: Chy400_0748

Alternate gene names: 222524033

Gene position: 933094-932534 (Counterclockwise)

Preceding gene: 222524040

Following gene: 222524032

Centisome position: 17.71

GC content: 55.97

Gene sequence:

>561_bases
GTGTCCACTATTCCAACAACCCGATCAGGACTTGTCGTCTGGTTTACCGGGCTTTCTGGCGCCGGGAAAACAACGCTGGC
ACGGGCGCTGGCGACGCTGTTGCAAGAGGCCGGCTACCCGGTTGAACAGCTCGATGGCGATGTCGTTCGTGAACATTTGT
CGAAGGGGTTAGGGTTTAGCCGCGAAGATCGTGATACGAATATCCGGCGGATTGGTTTTGTAGCCAATTTGCTGGCCAAA
CACGGTGTGATCGTGTTGGTCAGTGCGATCAGTCCCTACCGGGAAACACGTGCTGAGGTGCTGGCTGCCGCACCCAGAAA
ACTTGAGGTGTTTGTGGAGGCACCGCTAGATGTCCTCATTCAGCGTGATGTGAAGGGGCTGTACGCGAAGGCGTTGCGCG
GCGAGATTGCGCAATTTACCGGTATCTCTGACCCTTACGAACCTCCGTTGCATCCCGATGTCCATCTGCGCACCGATCTG
ATGAGTTTGCCGGAGTGTCTGGATCATCTGCTGGCTGCGCTGGAACGGCTGGATATTGTGGTGAAGGTGAGTCACCAATG
A

Upstream 100 bases:

>100_bases
CCGCTGCCATTTGGGAGACCGAAACTTTGCGGGCCGTAGCATCGATATGCTACGAGTGGTCTGCTGTACTCAATTACAGT
CTTGGGATAAGGAGATGTTT

Downstream 100 bases:

>100_bases
CAACACAATACTGGGACGCGAACACCGACCCTCGTGATGTCATTCGCTGGGCACTTGCCGGTTATCCCGATCTGCTGATG
ACCAGTGCATTCAATCTTAA

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSTIPTTRSGLVVWFTGLSGAGKTTLARALATLLQEAGYPVEQLDGDVVREHLSKGLGFSREDRDTNIRRIGFVANLLAK
HGVIVLVSAISPYRETRAEVLAAAPRKLEVFVEAPLDVLIQRDVKGLYAKALRGEIAQFTGISDPYEPPLHPDVHLRTDL
MSLPECLDHLLAALERLDIVVKVSHQ

Sequences:

>Translated_186_residues
MSTIPTTRSGLVVWFTGLSGAGKTTLARALATLLQEAGYPVEQLDGDVVREHLSKGLGFSREDRDTNIRRIGFVANLLAK
HGVIVLVSAISPYRETRAEVLAAAPRKLEVFVEAPLDVLIQRDVKGLYAKALRGEIAQFTGISDPYEPPLHPDVHLRTDL
MSLPECLDHLLAALERLDIVVKVSHQ
>Mature_185_residues
STIPTTRSGLVVWFTGLSGAGKTTLARALATLLQEAGYPVEQLDGDVVREHLSKGLGFSREDRDTNIRRIGFVANLLAKH
GVIVLVSAISPYRETRAEVLAAAPRKLEVFVEAPLDVLIQRDVKGLYAKALRGEIAQFTGISDPYEPPLHPDVHLRTDLM
SLPECLDHLLAALERLDIVVKVSHQ

Specific function: Catalyzes the synthesis of activated sulfate

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family

Homologues:

Organism=Homo sapiens, GI46094058, Length=175, Percent_Identity=48.5714285714286, Blast_Score=156, Evalue=9e-39,
Organism=Homo sapiens, GI34447231, Length=175, Percent_Identity=44.5714285714286, Blast_Score=144, Evalue=4e-35,
Organism=Homo sapiens, GI62912492, Length=175, Percent_Identity=44.5714285714286, Blast_Score=144, Evalue=5e-35,
Organism=Escherichia coli, GI1789107, Length=173, Percent_Identity=45.6647398843931, Blast_Score=138, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17542422, Length=170, Percent_Identity=44.7058823529412, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6322852, Length=163, Percent_Identity=49.079754601227, Blast_Score=149, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24667032, Length=175, Percent_Identity=45.1428571428571, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24667028, Length=175, Percent_Identity=45.1428571428571, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24667036, Length=175, Percent_Identity=45.1428571428571, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24667040, Length=175, Percent_Identity=45.1428571428571, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI116007838, Length=175, Percent_Identity=45.1428571428571, Blast_Score=137, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24667044, Length=175, Percent_Identity=45.1428571428571, Blast_Score=137, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSC_CHLSY (B9LKC1)

Other databases:

- EMBL:   CP001364
- RefSeq:   YP_002568503.1
- ProteinModelPortal:   B9LKC1
- GeneID:   7405887
- GenomeReviews:   CP001364_GR
- KEGG:   chl:Chy400_0748
- OMA:   ITITAFV
- ProtClustDB:   PRK00889
- HAMAP:   MF_00065
- InterPro:   IPR002891
- TIGRFAMs:   TIGR00455

Pfam domain/function: PF01583 APS_kinase

EC number: =2.7.1.25

Molecular weight: Translated: 20383; Mature: 20252

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: ACT_SITE 91-91

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIPTTRSGLVVWFTGLSGAGKTTLARALATLLQEAGYPVEQLDGDVVREHLSKGLGFS
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCC
REDRDTNIRRIGFVANLLAKHGVIVLVSAISPYRETRAEVLAAAPRKLEVFVEAPLDVLI
CCCCCCCHHHHHHHHHHHHHCCCEEEEEHHCHHHHHHHHHHHHCCCCEEEEECCHHHHHH
QRDVKGLYAKALRGEIAQFTGISDPYEPPLHPDVHLRTDLMSLPECLDHLLAALERLDIV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
VKVSHQ
EEECCC
>Mature Secondary Structure 
STIPTTRSGLVVWFTGLSGAGKTTLARALATLLQEAGYPVEQLDGDVVREHLSKGLGFS
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCC
REDRDTNIRRIGFVANLLAKHGVIVLVSAISPYRETRAEVLAAAPRKLEVFVEAPLDVLI
CCCCCCCHHHHHHHHHHHHHCCCEEEEEHHCHHHHHHHHHHHHCCCCEEEEECCHHHHHH
QRDVKGLYAKALRGEIAQFTGISDPYEPPLHPDVHLRTDLMSLPECLDHLLAALERLDIV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
VKVSHQ
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA