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The map label for this gene is pdp [H]

Identifier: 222523799

GI number: 222523799

Start: 605455

End: 606759

Strand: Reverse

Name: pdp [H]

Synonym: Chy400_0507

Alternate gene names: 222523799

Gene position: 606759-605455 (Counterclockwise)

Preceding gene: 222523800

Following gene: 222523798

Centisome position: 11.52

GC content: 57.93

Gene sequence:

>1305_bases
ATGCGTATGGTAGAAATTATTGCCGCGAAACGAGATGGCCGTGCATTGACCACCGAAGAGATTGAATGGGTTGTCGCGAA
CTATGCAGCCGGTGCGATTCCCGATTATCAGATGGCTGCCCTGGCGATGGCCATCGTGTTGCGCGGGATGGATGATCGCG
AAACGGCTGATCTGACCATCGCCATGGCTCGCAGCGGCGATATGCTCGATCTCCACGATATTGCGCCACTGACGGTTGAC
AAGCATTCAACCGGTGGTGTCGGTGACAAAACGACCCTGGTACTGGCCCCCCTGGTCGCCGCCGTTGGCCTGCCGGTGGC
AAAAATGAGTGGCAGGGGACTGGGTTTTAGCGGCGGCACGATTGATAAGCTGGAGAGCATTCGCGGCTTTCGCACCAATC
TCAGTGCCGATGAGTTTCGGCGCGCGGTGCGTGAACTGGGGCTGGTGGTGGCTGCCCAAAGCGGCGATCTGGCACCGGCT
GACAAAAAACTCTACGCCCTCCGCGATGTCACTGCCACCGTCGAGTCAATTCCATTGATCGCGGCCAGTGTGATGAGTAA
GAAGCTGGCATCGGGTGCTGATTGTATCGTGCTCGATGTAAAATATGGACGTGGCGCCTTCATGCAGACACTCGCCGATG
CCCGTCGCCTGGCCCAAACGATGGTGGCAATCGGTCGGCATGCAGGGCGTAGAGTTGCTGCGGTGCTGAGCAGTATGCAA
CAGCCGCTCGGTTTTGCGGTCGGTAATGCGCTGGAAGTGCGCGAAGCCATTGCAGCTTTGCGTGGTTCTGGGCCGTCTGA
TCTGGTTGAGCTGTGCCTTGTGTTGGGGAGTGAACTGGTACGCATGGCCGGCCTACGCAACGACAGTGATGCCGCACGTG
CGTTGTTGAGTGAGGCATTGCAGTCGGGTGCAGCCTGGGAAAAGTTTCGGGCCATGGTCATCAATCAGGGTGGCGATCCA
GAAGTGATTGATCATCCCGAACGCCTGCCGGTCGCTCCCGTGCAGGTCGATCTCCCGGCACCACGGGCCGGTTTTGTGAC
GGCGATTGATGGTCAGGCATTGGGGTTAGCGGTCAATGCGCTGGGTGGCGGACGTTCACGCAAAGAAGATACCATTGACC
ATGCGGTAGGCCTGGTCTTGCAGGCAAAAGTTGGTGATGCAGTGAAGGCAGGTGATCCACTGCTCACCATCCACGCGGCA
CGTGAAACTGATGTCGATCATGTTGCCGAACGGCTCCAGCTTGCCTATACTATCCATGATACGCCACCACCGCCATTGCC
CTTGGTTGAAGAGATTATCCGGTAA

Upstream 100 bases:

>100_bases
GCGTCGTTGCCGGTGATTTGTTGCCGCTGTTGCCATCAGTCATGCAAGAGTTGCGCACCGGCTAAGCTGCCGGGCCAGGA
CGTAGAAAGGAATGCCTGCC

Downstream 100 bases:

>100_bases
AGCCGGGTGACCAGGAAATAGAGGTTGCTATGCCAATCTACGAGTATCTCTGTCCAGCATGTAACGGTCAGTTTCAAAAA
CTGGTACGTGGATTCAGTGA

Product: pyrimidine-nucleoside phosphorylase

Products: NA

Alternate protein names: PYNP [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRMVEIIAAKRDGRALTTEEIEWVVANYAAGAIPDYQMAALAMAIVLRGMDDRETADLTIAMARSGDMLDLHDIAPLTVD
KHSTGGVGDKTTLVLAPLVAAVGLPVAKMSGRGLGFSGGTIDKLESIRGFRTNLSADEFRRAVRELGLVVAAQSGDLAPA
DKKLYALRDVTATVESIPLIAASVMSKKLASGADCIVLDVKYGRGAFMQTLADARRLAQTMVAIGRHAGRRVAAVLSSMQ
QPLGFAVGNALEVREAIAALRGSGPSDLVELCLVLGSELVRMAGLRNDSDAARALLSEALQSGAAWEKFRAMVINQGGDP
EVIDHPERLPVAPVQVDLPAPRAGFVTAIDGQALGLAVNALGGGRSRKEDTIDHAVGLVLQAKVGDAVKAGDPLLTIHAA
RETDVDHVAERLQLAYTIHDTPPPPLPLVEEIIR

Sequences:

>Translated_434_residues
MRMVEIIAAKRDGRALTTEEIEWVVANYAAGAIPDYQMAALAMAIVLRGMDDRETADLTIAMARSGDMLDLHDIAPLTVD
KHSTGGVGDKTTLVLAPLVAAVGLPVAKMSGRGLGFSGGTIDKLESIRGFRTNLSADEFRRAVRELGLVVAAQSGDLAPA
DKKLYALRDVTATVESIPLIAASVMSKKLASGADCIVLDVKYGRGAFMQTLADARRLAQTMVAIGRHAGRRVAAVLSSMQ
QPLGFAVGNALEVREAIAALRGSGPSDLVELCLVLGSELVRMAGLRNDSDAARALLSEALQSGAAWEKFRAMVINQGGDP
EVIDHPERLPVAPVQVDLPAPRAGFVTAIDGQALGLAVNALGGGRSRKEDTIDHAVGLVLQAKVGDAVKAGDPLLTIHAA
RETDVDHVAERLQLAYTIHDTPPPPLPLVEEIIR
>Mature_434_residues
MRMVEIIAAKRDGRALTTEEIEWVVANYAAGAIPDYQMAALAMAIVLRGMDDRETADLTIAMARSGDMLDLHDIAPLTVD
KHSTGGVGDKTTLVLAPLVAAVGLPVAKMSGRGLGFSGGTIDKLESIRGFRTNLSADEFRRAVRELGLVVAAQSGDLAPA
DKKLYALRDVTATVESIPLIAASVMSKKLASGADCIVLDVKYGRGAFMQTLADARRLAQTMVAIGRHAGRRVAAVLSSMQ
QPLGFAVGNALEVREAIAALRGSGPSDLVELCLVLGSELVRMAGLRNDSDAARALLSEALQSGAAWEKFRAMVINQGGDP
EVIDHPERLPVAPVQVDLPAPRAGFVTAIDGQALGLAVNALGGGRSRKEDTIDHAVGLVLQAKVGDAVKAGDPLLTIHAA
RETDVDHVAERLQLAYTIHDTPPPPLPLVEEIIR

Specific function: The Enzymes Which Catalyze The Reversible Phosphorolysis Of Pyrimidine Nucleosides Are Involved In The Degradation Of These Compounds And In Their Utilization As Carbon And Energy Sources, Or In The Rescue Of Pyrimidine Bases For Nucleotide Synthesis. [C

COG id: COG0213

COG function: function code F; Thymidine phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI166158925, Length=444, Percent_Identity=41.2162162162162, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI4503445, Length=444, Percent_Identity=41.2162162162162, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI166158922, Length=444, Percent_Identity=41.2162162162162, Blast_Score=276, Evalue=2e-74,
Organism=Escherichia coli, GI1790842, Length=430, Percent_Identity=43.953488372093, Blast_Score=311, Evalue=8e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR013102
- InterPro:   IPR018090
- InterPro:   IPR000053
- InterPro:   IPR017872 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; PF07831 PYNP_C [H]

EC number: =2.4.2.2 [H]

Molecular weight: Translated: 45721; Mature: 45721

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMVEIIAAKRDGRALTTEEIEWVVANYAAGAIPDYQMAALAMAIVLRGMDDRETADLTI
CCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEE
AMARSGDMLDLHDIAPLTVDKHSTGGVGDKTTLVLAPLVAAVGLPVAKMSGRGLGFSGGT
EEECCCCEEEHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCC
IDKLESIRGFRTNLSADEFRRAVRELGLVVAAQSGDLAPADKKLYALRDVTATVESIPLI
HHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
AASVMSKKLASGADCIVLDVKYGRGAFMQTLADARRLAQTMVAIGRHAGRRVAAVLSSMQ
HHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
QPLGFAVGNALEVREAIAALRGSGPSDLVELCLVLGSELVRMAGLRNDSDAARALLSEAL
HHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QSGAAWEKFRAMVINQGGDPEVIDHPERLPVAPVQVDLPAPRAGFVTAIDGQALGLAVNA
HCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCEEEEEEEC
LGGGRSRKEDTIDHAVGLVLQAKVGDAVKAGDPLLTIHAARETDVDHVAERLQLAYTIHD
CCCCCCCCHHHHHHHHHHHEEECCCCHHHCCCCEEEEEECCCCCHHHHHHHHHEEEEEEC
TPPPPLPLVEEIIR
CCCCCCHHHHHHHC
>Mature Secondary Structure
MRMVEIIAAKRDGRALTTEEIEWVVANYAAGAIPDYQMAALAMAIVLRGMDDRETADLTI
CCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEE
AMARSGDMLDLHDIAPLTVDKHSTGGVGDKTTLVLAPLVAAVGLPVAKMSGRGLGFSGGT
EEECCCCEEEHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCC
IDKLESIRGFRTNLSADEFRRAVRELGLVVAAQSGDLAPADKKLYALRDVTATVESIPLI
HHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
AASVMSKKLASGADCIVLDVKYGRGAFMQTLADARRLAQTMVAIGRHAGRRVAAVLSSMQ
HHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
QPLGFAVGNALEVREAIAALRGSGPSDLVELCLVLGSELVRMAGLRNDSDAARALLSEAL
HHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QSGAAWEKFRAMVINQGGDPEVIDHPERLPVAPVQVDLPAPRAGFVTAIDGQALGLAVNA
HCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCEEEEEEEC
LGGGRSRKEDTIDHAVGLVLQAKVGDAVKAGDPLLTIHAARETDVDHVAERLQLAYTIHD
CCCCCCCCHHHHHHHHHHHEEECCCCHHHCCCCEEEEEECCCCCHHHHHHHHHEEEEEEC
TPPPPLPLVEEIIR
CCCCCCHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA