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The map label for this gene is degP [C]

Identifier: 222523625

GI number: 222523625

Start: 396051

End: 397241

Strand: Reverse

Name: degP [C]

Synonym: Chy400_0331

Alternate gene names: 222523625

Gene position: 397241-396051 (Counterclockwise)

Preceding gene: 222523626

Following gene: 222523624

Centisome position: 7.54

GC content: 57.85

Gene sequence:

>1191_bases
ATGGAGCGTCAATCTGGACGCGGTCGCTGGATCGTTCTTTTTATCGAGCTGGCCCTGCTTGTCGTAATTGCCGGCGCTTT
TGTCTGGACAGCATTCACCGGCAATCGTCCGGCGACCATTGTCGTTGCCCCGTCTCCCACGCCGGTTGTATTGCCGGCGC
CGACGGTCGTGCCGCTCACCGCTACCGATCTGGAAGCGCAGATCGCTGCCGTCTACCGCGAAGCTGGTGTCAGTGTGGTG
AATATTACCAGTCGCTCAATCAGTTACGATTTCTTCTTCAACCCGGTACCACGGCAGGGTAGTGGTTCGGGCTTTTTCTA
CGATGACCAGGGACATATCGTTACCAACTATCACGTGATCGCCGATGCTGACGAACTACAGGTGACGCTGGCCGATGGTC
AGACGGTGCCGGCCCGGATTGTTGGCAGCGATCCGTCGAACGATCTGGCCGTGATCAAGGTTGATCTGCCGACAGCGACA
ATTCGTCCGCTGCCAATTGGCGACTCAACCCAGGTCTATGTTGGTCAATTTGTGCTGGCTATCGGTAATCCGTTCGGATT
GGAGCGTACCCTGACCTTTGGTATCGTCAGTGCTTTGGGCCGAGTGATTGAGAGTCCCAACCAGCGCTTTATCGGCGAAG
TGATTCAATCCGATGTCGCGATCAACCCCGGTAACTCCGGTGGCCCGCTGCTCGATCTCTCCGGTCGGGTGATCGGTGTT
AACTCGGCGATTCTCAGTCCGAGCGGGGCAAATGCCGGGATCGGTTTTGCCATCTCGTCTCGGACTGTCCAGCGGGTTGT
TCCCGTCCTGATCCGTGAGGGACGCTATCCGCATCCGTCACTGGGTGTGCGTGTGATCGAGTTAACCCCACAGCGGGCCA
GTCTGTTCGAGCGAGCCGGTATGCAGTTGCCGGTAACGCAGGGGTTGCTGATCGCAGAGTTGATCACGAACGGGCCGGCG
GCCCAGGCTGGATTACGCGGCCCTGATCGCCTCGTGCGGGTAGGTAATTTAAACCTGCCGGTCGGCGGCGATGTCATCGT
TGCCGTCAATGATCGGCCCATCACGACCAGTCAAGACCTGCTCGTCTATCTTGAGACCGAGACACAGGTAGGCGAAACGG
TGCAGGTCAAGATCATTCGTGATGGTCGTGAGCAGGTGGTGCCGGTAACGCTGGCTGAATTGCAATTCTAA

Upstream 100 bases:

>100_bases
TGATAGCGGATAATCAGGTGGCAACTGAGGTTATACATATCCTCTGTGTCTCTGTGGTGAGAAATGCACCACATTAGAAC
TACATCATTGCGAGGTGATT

Downstream 100 bases:

>100_bases
GCTAAGGAGACACCGCCTATGCTTGTGCGACGGATGAGTTTAGAGGAGCTGGCTGTAGCAGTTGGTCTGCCGGTACCGGT
CTTGCAATACCTGACCGACA

Product: 2-alkenal reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MERQSGRGRWIVLFIELALLVVIAGAFVWTAFTGNRPATIVVAPSPTPVVLPAPTVVPLTATDLEAQIAAVYREAGVSVV
NITSRSISYDFFFNPVPRQGSGSGFFYDDQGHIVTNYHVIADADELQVTLADGQTVPARIVGSDPSNDLAVIKVDLPTAT
IRPLPIGDSTQVYVGQFVLAIGNPFGLERTLTFGIVSALGRVIESPNQRFIGEVIQSDVAINPGNSGGPLLDLSGRVIGV
NSAILSPSGANAGIGFAISSRTVQRVVPVLIREGRYPHPSLGVRVIELTPQRASLFERAGMQLPVTQGLLIAELITNGPA
AQAGLRGPDRLVRVGNLNLPVGGDVIVAVNDRPITTSQDLLVYLETETQVGETVQVKIIRDGREQVVPVTLAELQF

Sequences:

>Translated_396_residues
MERQSGRGRWIVLFIELALLVVIAGAFVWTAFTGNRPATIVVAPSPTPVVLPAPTVVPLTATDLEAQIAAVYREAGVSVV
NITSRSISYDFFFNPVPRQGSGSGFFYDDQGHIVTNYHVIADADELQVTLADGQTVPARIVGSDPSNDLAVIKVDLPTAT
IRPLPIGDSTQVYVGQFVLAIGNPFGLERTLTFGIVSALGRVIESPNQRFIGEVIQSDVAINPGNSGGPLLDLSGRVIGV
NSAILSPSGANAGIGFAISSRTVQRVVPVLIREGRYPHPSLGVRVIELTPQRASLFERAGMQLPVTQGLLIAELITNGPA
AQAGLRGPDRLVRVGNLNLPVGGDVIVAVNDRPITTSQDLLVYLETETQVGETVQVKIIRDGREQVVPVTLAELQF
>Mature_396_residues
MERQSGRGRWIVLFIELALLVVIAGAFVWTAFTGNRPATIVVAPSPTPVVLPAPTVVPLTATDLEAQIAAVYREAGVSVV
NITSRSISYDFFFNPVPRQGSGSGFFYDDQGHIVTNYHVIADADELQVTLADGQTVPARIVGSDPSNDLAVIKVDLPTAT
IRPLPIGDSTQVYVGQFVLAIGNPFGLERTLTFGIVSALGRVIESPNQRFIGEVIQSDVAINPGNSGGPLLDLSGRVIGV
NSAILSPSGANAGIGFAISSRTVQRVVPVLIREGRYPHPSLGVRVIELTPQRASLFERAGMQLPVTQGLLIAELITNGPA
AQAGLRGPDRLVRVGNLNLPVGGDVIVAVNDRPITTSQDLLVYLETETQVGETVQVKIIRDGREQVVPVTLAELQF

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=304, Percent_Identity=31.5789473684211, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI22129776, Length=316, Percent_Identity=32.2784810126582, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI7019477, Length=317, Percent_Identity=34.7003154574132, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI24308541, Length=278, Percent_Identity=33.0935251798561, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1786356, Length=293, Percent_Identity=36.8600682593857, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1789629, Length=308, Percent_Identity=35.3896103896104, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI1789630, Length=329, Percent_Identity=34.3465045592705, Blast_Score=156, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24646839, Length=338, Percent_Identity=29.2899408284024, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 42072; Mature: 42072

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERQSGRGRWIVLFIELALLVVIAGAFVWTAFTGNRPATIVVAPSPTPVVLPAPTVVPLT
CCCCCCCCCEEEEHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCCEEECCCCEEEEE
ATDLEAQIAAVYREAGVSVVNITSRSISYDFFFNPVPRQGSGSGFFYDDQGHIVTNYHVI
ECCHHHHHHHHHHHCCCEEEEEECCEEEEEEEECCCCCCCCCCCEEECCCCCEEEEEEEE
ADADELQVTLADGQTVPARIVGSDPSNDLAVIKVDLPTATIRPLPIGDSTQVYVGQFVLA
ECCCCEEEEEECCCCCCEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCEEEEEEEEEE
IGNPFGLERTLTFGIVSALGRVIESPNQRFIGEVIQSDVAINPGNSGGPLLDLSGRVIGV
ECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEECCCCCCCCEEEECCCEEEE
NSAILSPSGANAGIGFAISSRTVQRVVPVLIREGRYPHPSLGVRVIELTPQRASLFERAG
CCEEECCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHCC
MQLPVTQGLLIAELITNGPAAQAGLRGPDRLVRVGNLNLPVGGDVIVAVNDRPITTSQDL
CCCCHHCCHHHHHHHCCCCCCCCCCCCHHHEEEECCCCCCCCCCEEEEECCCCCCCCCCE
LVYLETETQVGETVQVKIIRDGREQVVPVTLAELQF
EEEEECCCCCCCEEEEEEEECCCCEEEEEEEEEECC
>Mature Secondary Structure
MERQSGRGRWIVLFIELALLVVIAGAFVWTAFTGNRPATIVVAPSPTPVVLPAPTVVPLT
CCCCCCCCCEEEEHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCCEEECCCCEEEEE
ATDLEAQIAAVYREAGVSVVNITSRSISYDFFFNPVPRQGSGSGFFYDDQGHIVTNYHVI
ECCHHHHHHHHHHHCCCEEEEEECCEEEEEEEECCCCCCCCCCCEEECCCCCEEEEEEEE
ADADELQVTLADGQTVPARIVGSDPSNDLAVIKVDLPTATIRPLPIGDSTQVYVGQFVLA
ECCCCEEEEEECCCCCCEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCEEEEEEEEEE
IGNPFGLERTLTFGIVSALGRVIESPNQRFIGEVIQSDVAINPGNSGGPLLDLSGRVIGV
ECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEECCCCCCCCEEEECCCEEEE
NSAILSPSGANAGIGFAISSRTVQRVVPVLIREGRYPHPSLGVRVIELTPQRASLFERAG
CCEEECCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHCC
MQLPVTQGLLIAELITNGPAAQAGLRGPDRLVRVGNLNLPVGGDVIVAVNDRPITTSQDL
CCCCHHCCHHHHHHHCCCCCCCCCCCCHHHEEEECCCCCCCCCCEEEEECCCCCCCCCCE
LVYLETETQVGETVQVKIIRDGREQVVPVTLAELQF
EEEEECCCCCCCEEEEEEEECCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA