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The map label for this gene is nhaA2 [H]

Identifier: 222523620

GI number: 222523620

Start: 391385

End: 392167

Strand: Reverse

Name: nhaA2 [H]

Synonym: Chy400_0326

Alternate gene names: 222523620

Gene position: 392167-391385 (Counterclockwise)

Preceding gene: 222523621

Following gene: 222523619

Centisome position: 7.44

GC content: 59.9

Gene sequence:

>783_bases
ATGCGTGTTCGTCTCCTGGTGCTAATAATGTTGCTCTCGCTGACAGCCTGTACCGCAGCGACACCAGTGCCGTCGCCTAC
AGCCATTCCTCGCCTACCCACAGTCACACCCGAACCATTGTCGCAAAGCACACCGACTCCACGCATCATTCGCCTGAGCG
AATCTCCTTTACCCGTCTTCACCCCAACACCAATCCCAACGCCGGTTATCTCTGCGGACGGCATCACCACCGCCAGTATG
GCGCAGCTTGGCATCAGTGCCGAACCGTATGCGATCCTGGGCGATCCCAACGCACCGGTGACCATCATCGAATTTACTGA
TTTTGGCTGTACCTTCTGCCGTCGCCACCACGTGCTCACCTTCCCTGCCTTGCGGGAAGAATTCATTTCCAGCGGCCAGG
TCTTCTACGTGGTCAGACAGCTCCCGGTCACCAGCCCGCATGGTGATCAGGCGGCGTTGGCTGCGCTATGTGCCGGCGAA
CAGGGCAAATACTGGGAGATGCACGACCAGCTCTTCGCCGCCGGCGATGCCTGGTACAGCGATGCTACCACTGCCCGCAG
GCGGATCATCGCGCTAGCGACCGATCTCGGTCTGGATAGCGCCGTGTTGCAACGCTGTATGGAACATCCGGCGACCCAGG
CGACGCTGGCCCGCCACGTGAGCGAAGCGCATGCCTTACGGGTGTTCGGTACGCCGACCTTTTTCATCAACAATCAGCTC
TTTGCCGGTGCCCAACCGATTGCACGCTGGCGTGATGTGTTGGAGGGAGGAGGGAGGAGATAG

Upstream 100 bases:

>100_bases
ACGCCTCATGGTAGCAACCCAGGTTATGCCCATTCTCTGTGTCCTCCGTGTCTCTGTGGTGACAAAGGTAGCAACTTGAG
TTGAAAGATAGGTTCTGCGC

Downstream 100 bases:

>100_bases
GAGATAGAAGATAGAAGGTAGAAAGTAGAAGATAGGATAGATAGAGGAGAAAGGGGAGAGGGGAGTGAGGGCATCTCCCT
CAACATATCTACCTGATACT

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MRVRLLVLIMLLSLTACTAATPVPSPTAIPRLPTVTPEPLSQSTPTPRIIRLSESPLPVFTPTPIPTPVISADGITTASM
AQLGISAEPYAILGDPNAPVTIIEFTDFGCTFCRRHHVLTFPALREEFISSGQVFYVVRQLPVTSPHGDQAALAALCAGE
QGKYWEMHDQLFAAGDAWYSDATTARRRIIALATDLGLDSAVLQRCMEHPATQATLARHVSEAHALRVFGTPTFFINNQL
FAGAQPIARWRDVLEGGGRR

Sequences:

>Translated_260_residues
MRVRLLVLIMLLSLTACTAATPVPSPTAIPRLPTVTPEPLSQSTPTPRIIRLSESPLPVFTPTPIPTPVISADGITTASM
AQLGISAEPYAILGDPNAPVTIIEFTDFGCTFCRRHHVLTFPALREEFISSGQVFYVVRQLPVTSPHGDQAALAALCAGE
QGKYWEMHDQLFAAGDAWYSDATTARRRIIALATDLGLDSAVLQRCMEHPATQATLARHVSEAHALRVFGTPTFFINNQL
FAGAQPIARWRDVLEGGGRR
>Mature_260_residues
MRVRLLVLIMLLSLTACTAATPVPSPTAIPRLPTVTPEPLSQSTPTPRIIRLSESPLPVFTPTPIPTPVISADGITTASM
AQLGISAEPYAILGDPNAPVTIIEFTDFGCTFCRRHHVLTFPALREEFISSGQVFYVVRQLPVTSPHGDQAALAALCAGE
QGKYWEMHDQLFAAGDAWYSDATTARRRIIALATDLGLDSAVLQRCMEHPATQATLARHVSEAHALRVFGTPTFFINNQL
FAGAQPIARWRDVLEGGGRR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 28180; Mature: 28180

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVRLLVLIMLLSLTACTAATPVPSPTAIPRLPTVTPEPLSQSTPTPRIIRLSESPLPVF
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEE
TPTPIPTPVISADGITTASMAQLGISAEPYAILGDPNAPVTIIEFTDFGCTFCRRHHVLT
CCCCCCCCEECCCCCCHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCHHHHHCCCEEE
FPALREEFISSGQVFYVVRQLPVTSPHGDQAALAALCAGEQGKYWEMHDQLFAAGDAWYS
CHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEHHHHHHHHCCCCHHC
DATTARRRIIALATDLGLDSAVLQRCMEHPATQATLARHVSEAHALRVFGTPTFFINNQL
CHHHHHHEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCEEEECCCE
FAGAQPIARWRDVLEGGGRR
ECCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRVRLLVLIMLLSLTACTAATPVPSPTAIPRLPTVTPEPLSQSTPTPRIIRLSESPLPVF
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEE
TPTPIPTPVISADGITTASMAQLGISAEPYAILGDPNAPVTIIEFTDFGCTFCRRHHVLT
CCCCCCCCEECCCCCCHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCHHHHHCCCEEE
FPALREEFISSGQVFYVVRQLPVTSPHGDQAALAALCAGEQGKYWEMHDQLFAAGDAWYS
CHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEHHHHHHHHCCCCHHC
DATTARRRIIALATDLGLDSAVLQRCMEHPATQATLARHVSEAHALRVFGTPTFFINNQL
CHHHHHHEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCEEEECCCE
FAGAQPIARWRDVLEGGGRR
ECCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA