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The map label for this gene is 222523572

Identifier: 222523572

GI number: 222523572

Start: 335270

End: 336547

Strand: Direct

Name: 222523572

Synonym: Chy400_0278

Alternate gene names: NA

Gene position: 335270-336547 (Clockwise)

Preceding gene: 222523571

Following gene: 222523577

Centisome position: 6.36

GC content: 61.19

Gene sequence:

>1278_bases
ATGCAGGTACACACTATCAGCATCCCCCCGGCATTAGGTGAGGCGACGTTACTGGAATGGCTGGTTGCCGTTGGCGAGTC
TGTCACACCGACAACGCCGCTTGCCCGTGTCTTAACCGCACACGCCGAGTGGGTTATCCCGGCTCAGTACGTAGGAATTG
TGGCTGAGCACGTGGTGGCCGCAGGGGCAACAATCCCGGTAGGGGGAGAACTGGCCCGTTGTACTCCGCCACCACGGGTA
CGGGCGACGCCCCTGGCCCGCCGGCTGGCAACCGCGTTGGGGGTTGACCTGACGGCTCTCGCCGGAAGTGGCCCCGGCGG
TCGCATCATGCGTGCCGATGTTGTCAAAGCTGTGGATGTAGCTTCCGGCTCATCAGACTCTCTCCCTCCACCGGCAGTGG
TAGGAGATACGGTGCATGCCAGAGCGGTAGCAGATGCAACGGTCGGTACGATTGTGTCGTCGACCACTGAGCTACGAATT
GTTGATGCGCAGCCGGTACCACTTGCCGGCGCGACGGTTGCGGCTGTGGATGTTGCTTCCGACTTATCAGACTCTCTCCC
TCCACCGGCAGTGGTAGGAGATACGGTGCATGCCAGAGCGGTAGCAGATGCAACGGTCGGTACGAATACGTCGTCGACCA
TTAGGCTGCGCATTGTTGATGCGCAGCCAGTCCCGCTTGCCAGCGCGACGATTGCGATTGATCTGCAATCGGTGTTGCAC
CAATGCCGGGTGCAGAACGCGACGTTTGCCAGGTATGGCCTGCAAGCGACCCCTCAGAGCGCTCTGATCGCAGCCGCAGC
CGGCCTCTTTCCTGAGCATCCTCTGATTAATGCCGCCTGGACTGAGACGGCTATCGTACTGCGCCATCGGTATCACGTAG
CTGCCGGTTTAACCGATGGCCGCTGGGTGTTGATTCGCGATGCCGGTGATCTTAACGAACGTGGCATTGCCCGCGCCTTG
ACCGGAACGGGTCACGATCTGGGGATGGCAACCTGTGCGATTGCCGTGACTGCTGATTGGTGGCAGATCACGCCGCCCTT
GCCGGGAACGGTAGCAGCATTGACGCTGAGCGAAGCGCAGCTTAAGCCGGTGGCCCTCGGTGATACGACGATTGCAGTCG
GGGCAGTGGCACACCTGAGCCTCTGCTACGATGCGCGGGTGCTTGATCATCCGACGGCGATGGCATTTCTGAACGCGCTC
TGTCGGCGGCTCGGTGTCAGGCCGCTAGCCGAACCGCAAGAGGATGAGGTCGGTCTTGTGTCATCAGGCATTGCCTGA

Upstream 100 bases:

>100_bases
ATCCTGAACTTAAGCGTCCTGAACATGACCTTTTGCGGCGAAAAGTGAATGACTTTTGGGCTGCGGCGACGCAGTCCGGT
TGAAGCGATGAGGCTTGAAG

Downstream 100 bases:

>100_bases
AGCACATCGTTTGGGGAGCACGTCGCAGGAGCGTACAAGGCGCAGGGAAGCGACTATTTTATGCGCGGAAATCAGTAGGG
GCACGGCATGCCGTGCCCCC

Product: E3 binding domain-containing protein

Products: CoA; enzyme N6-(S-succinyldihydrolipoyl)lysine

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MQVHTISIPPALGEATLLEWLVAVGESVTPTTPLARVLTAHAEWVIPAQYVGIVAEHVVAAGATIPVGGELARCTPPPRV
RATPLARRLATALGVDLTALAGSGPGGRIMRADVVKAVDVASGSSDSLPPPAVVGDTVHARAVADATVGTIVSSTTELRI
VDAQPVPLAGATVAAVDVASDLSDSLPPPAVVGDTVHARAVADATVGTNTSSTIRLRIVDAQPVPLASATIAIDLQSVLH
QCRVQNATFARYGLQATPQSALIAAAAGLFPEHPLINAAWTETAIVLRHRYHVAAGLTDGRWVLIRDAGDLNERGIARAL
TGTGHDLGMATCAIAVTADWWQITPPLPGTVAALTLSEAQLKPVALGDTTIAVGAVAHLSLCYDARVLDHPTAMAFLNAL
CRRLGVRPLAEPQEDEVGLVSSGIA

Sequences:

>Translated_425_residues
MQVHTISIPPALGEATLLEWLVAVGESVTPTTPLARVLTAHAEWVIPAQYVGIVAEHVVAAGATIPVGGELARCTPPPRV
RATPLARRLATALGVDLTALAGSGPGGRIMRADVVKAVDVASGSSDSLPPPAVVGDTVHARAVADATVGTIVSSTTELRI
VDAQPVPLAGATVAAVDVASDLSDSLPPPAVVGDTVHARAVADATVGTNTSSTIRLRIVDAQPVPLASATIAIDLQSVLH
QCRVQNATFARYGLQATPQSALIAAAAGLFPEHPLINAAWTETAIVLRHRYHVAAGLTDGRWVLIRDAGDLNERGIARAL
TGTGHDLGMATCAIAVTADWWQITPPLPGTVAALTLSEAQLKPVALGDTTIAVGAVAHLSLCYDARVLDHPTAMAFLNAL
CRRLGVRPLAEPQEDEVGLVSSGIA
>Mature_425_residues
MQVHTISIPPALGEATLLEWLVAVGESVTPTTPLARVLTAHAEWVIPAQYVGIVAEHVVAAGATIPVGGELARCTPPPRV
RATPLARRLATALGVDLTALAGSGPGGRIMRADVVKAVDVASGSSDSLPPPAVVGDTVHARAVADATVGTIVSSTTELRI
VDAQPVPLAGATVAAVDVASDLSDSLPPPAVVGDTVHARAVADATVGTNTSSTIRLRIVDAQPVPLASATIAIDLQSVLH
QCRVQNATFARYGLQATPQSALIAAAAGLFPEHPLINAAWTETAIVLRHRYHVAAGLTDGRWVLIRDAGDLNERGIARAL
TGTGHDLGMATCAIAVTADWWQITPPLPGTVAALTLSEAQLKPVALGDTTIAVGAVAHLSLCYDARVLDHPTAMAFLNAL
CRRLGVRPLAEPQEDEVGLVSSGIA

Specific function: Unknown

COG id: COG0508

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.61

Molecular weight: Translated: 43619; Mature: 43619

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVHTISIPPALGEATLLEWLVAVGESVTPTTPLARVLTAHAEWVIPAQYVGIVAEHVVA
CEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECHHHHHHHHHHHHHH
AGATIPVGGELARCTPPPRVRATPLARRLATALGVDLTALAGSGPGGRIMRADVVKAVDV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEHHHHHHHHHC
ASGSSDSLPPPAVVGDTVHARAVADATVGTIVSSTTELRIVDAQPVPLAGATVAAVDVAS
CCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEHHHHH
DLSDSLPPPAVVGDTVHARAVADATVGTNTSSTIRLRIVDAQPVPLASATIAIDLQSVLH
HHHHCCCCCCEECCCCHHHHEECCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEHHHHHH
QCRVQNATFARYGLQATPQSALIAAAAGLFPEHPLINAAWTETAIVLRHRYHVAAGLTDG
HHHCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHEEEHHHHEEEEECCCCC
RWVLIRDAGDLNERGIARALTGTGHDLGMATCAIAVTADWWQITPPLPGTVAALTLSEAQ
CEEEEECCCCCCCCCHHHHHCCCCCCHHHEEEEEEEEECCEEECCCCCCCEEEEEECCCC
LKPVALGDTTIAVGAVAHLSLCYDARVLDHPTAMAFLNALCRRLGVRPLAEPQEDEVGLV
CCEEEECCCHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
SSGIA
CCCCC
>Mature Secondary Structure
MQVHTISIPPALGEATLLEWLVAVGESVTPTTPLARVLTAHAEWVIPAQYVGIVAEHVVA
CEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECHHHHHHHHHHHHHH
AGATIPVGGELARCTPPPRVRATPLARRLATALGVDLTALAGSGPGGRIMRADVVKAVDV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEHHHHHHHHHC
ASGSSDSLPPPAVVGDTVHARAVADATVGTIVSSTTELRIVDAQPVPLAGATVAAVDVAS
CCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEHHHHH
DLSDSLPPPAVVGDTVHARAVADATVGTNTSSTIRLRIVDAQPVPLASATIAIDLQSVLH
HHHHCCCCCCEECCCCHHHHEECCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEHHHHHH
QCRVQNATFARYGLQATPQSALIAAAAGLFPEHPLINAAWTETAIVLRHRYHVAAGLTDG
HHHCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHEEEHHHHEEEEECCCCC
RWVLIRDAGDLNERGIARALTGTGHDLGMATCAIAVTADWWQITPPLPGTVAALTLSEAQ
CEEEEECCCCCCCCCHHHHHCCCCCCHHHEEEEEEEEECCEEECCCCCCCEEEEEECCCC
LKPVALGDTTIAVGAVAHLSLCYDARVLDHPTAMAFLNALCRRLGVRPLAEPQEDEVGLV
CCEEEECCCHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
SSGIA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinyl-CoA; enzyme N6-(dihydrolipoyl)lysine

Specific reaction: succinyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-succinyldihydrolipoyl)lysine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA