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The map label for this gene is ribD [H]

Identifier: 222523464

GI number: 222523464

Start: 195171

End: 195836

Strand: Direct

Name: ribD [H]

Synonym: Chy400_0169

Alternate gene names: 222523464

Gene position: 195171-195836 (Clockwise)

Preceding gene: 222523463

Following gene: 222523465

Centisome position: 3.7

GC content: 61.41

Gene sequence:

>666_bases
ATGATGCGTCCTCGGGTTACGCTATGTTTTGCCCAAACCCTCGATGGTCGGGTGGCAGCCGTTGACGGCAGCTCGCAGTG
GATCAGCGGCCCCGAATCGCTCCGCTTTTGTCATCACCTGCGGGCAAACAGTGATGCGATTATGGTTGGGGTTGGTACGG
TGTTACGCGATGATCCACGCCTCACCACGCGGCTGGTAGCAGGGCCTGATCCCTTGCGGGTGATTGTAGACACCCATCTC
CGCACACCAACGACCGCTGCCGTCATTCGTGATGGTGCCGGCACGGGTACCCTGCTGGCCTGCACTGCTGCGGCGCCGCT
TGAACGACGTATCGCCTTACAGGAATGCGGCGCGACGGTGCTGACTATGCCGGAAGCGGCTGGCGGTGGTGTCGATCTGG
CAGCACTCCTCACAGCGCTCGGCGAACGGGGTGTGGCGAGTGTGATGGTTGAAGGTGGTGCGCGCCTGATCACGAGTCTG
CTGCGCGCAAACCTGGTTGATGCGCTGGCAGTCACGATTGCGCCGATCATCCTCGGTAGTGGGCCGTCAGCTATCGGCGA
TCTGGGCATCCTCACGCTAAATCAGGCTCTGCGACTGACGAACGTCACCTGGACGACGTATGGCGCTGATGTGGTGATCG
AAGGCGATCTGGCACACCATCAGTAG

Upstream 100 bases:

>100_bases
ATCCGACGATAGTCGCAGTAGCGGTGCGGGTGACGAAACCGGGAGTGCGGTTGGGCGAGACAATCCTCGCCGGTTCGATG
GTAGAAATTGTGCGGCGAAG

Downstream 100 bases:

>100_bases
CAATCAGCGAAGCAGTCAAGACGGTATGAAACCCTTACCCGCGCAAGCCATCTGGTTTACCGCCCCCCACACGGTGAGCA
TCCGTGAGGAGATTGCTCCA

Product: 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MMRPRVTLCFAQTLDGRVAAVDGSSQWISGPESLRFCHHLRANSDAIMVGVGTVLRDDPRLTTRLVAGPDPLRVIVDTHL
RTPTTAAVIRDGAGTGTLLACTAAAPLERRIALQECGATVLTMPEAAGGGVDLAALLTALGERGVASVMVEGGARLITSL
LRANLVDALAVTIAPIILGSGPSAIGDLGILTLNQALRLTNVTWTTYGADVVIEGDLAHHQ

Sequences:

>Translated_221_residues
MMRPRVTLCFAQTLDGRVAAVDGSSQWISGPESLRFCHHLRANSDAIMVGVGTVLRDDPRLTTRLVAGPDPLRVIVDTHL
RTPTTAAVIRDGAGTGTLLACTAAAPLERRIALQECGATVLTMPEAAGGGVDLAALLTALGERGVASVMVEGGARLITSL
LRANLVDALAVTIAPIILGSGPSAIGDLGILTLNQALRLTNVTWTTYGADVVIEGDLAHHQ
>Mature_221_residues
MMRPRVTLCFAQTLDGRVAAVDGSSQWISGPESLRFCHHLRANSDAIMVGVGTVLRDDPRLTTRLVAGPDPLRVIVDTHL
RTPTTAAVIRDGAGTGTLLACTAAAPLERRIALQECGATVLTMPEAAGGGVDLAALLTALGERGVASVMVEGGARLITSL
LRANLVDALAVTIAPIILGSGPSAIGDLGILTLNQALRLTNVTWTTYGADVVIEGDLAHHQ

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=228, Percent_Identity=34.2105263157895, Blast_Score=93, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 22914; Mature: 22914

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRPRVTLCFAQTLDGRVAAVDGSSQWISGPESLRFCHHLRANSDAIMVGVGTVLRDDPR
CCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEECHHHCCCCC
LTTRLVAGPDPLRVIVDTHLRTPTTAAVIRDGAGTGTLLACTAAAPLERRIALQECGATV
CEEEEECCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHCCCEE
LTMPEAAGGGVDLAALLTALGERGVASVMVEGGARLITSLLRANLVDALAVTIAPIILGS
EECCCCCCCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
GPSAIGDLGILTLNQALRLTNVTWTTYGADVVIEGDLAHHQ
CCCHHHHHHHEEHHHHHEEEEEEEEECCCEEEEECCCCCCC
>Mature Secondary Structure
MMRPRVTLCFAQTLDGRVAAVDGSSQWISGPESLRFCHHLRANSDAIMVGVGTVLRDDPR
CCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEECHHHCCCCC
LTTRLVAGPDPLRVIVDTHLRTPTTAAVIRDGAGTGTLLACTAAAPLERRIALQECGATV
CEEEEECCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHCCCEE
LTMPEAAGGGVDLAALLTALGERGVASVMVEGGARLITSLLRANLVDALAVTIAPIILGS
EECCCCCCCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
GPSAIGDLGILTLNQALRLTNVTWTTYGADVVIEGDLAHHQ
CCCHHHHHHHEEHHHHHEEEEEEEEECCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]