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The map label for this gene is folB [H]

Identifier: 222523463

GI number: 222523463

Start: 194791

End: 195174

Strand: Direct

Name: folB [H]

Synonym: Chy400_0168

Alternate gene names: 222523463

Gene position: 194791-195174 (Clockwise)

Preceding gene: 222523462

Following gene: 222523464

Centisome position: 3.7

GC content: 58.07

Gene sequence:

>384_bases
ATGGATGAGTGGGGGATTGGGCACGACCGGATCATTCTGAGCGGGATGCAGTTTATCGGTTACCATGGCACTCGCCCCGA
AGAGAATCGACTCGGCCAGCGCTTTGTGGTTGATGTAGCCGTCCAGCTTGATTTGCAGGCAGCCGGTGTAAGCGATGATT
TGAGTCAGACGGTTGACTACAGTCAGATTCACGACCGGGTGCGCGAGATTGTCTGTGGGCCACCGCTCAAACTAACCGAG
GCCGTCGCCGAGCGGATTGCCGCTGCCGTCTTGCACGATCATCCGACGATAGTCGCAGTAGCGGTGCGGGTGACGAAACC
GGGAGTGCGGTTGGGCGAGACAATCCTCGCCGGTTCGATGGTAGAAATTGTGCGGCGAAGATGA

Upstream 100 bases:

>100_bases
ACGCGCATGGTGGCAACTCCGGAGCGCCGGATGTATCCCCCGGCAGATGTGCCTGCAATCCCGCTGATGTACGGTCTGGC
TGTAGAAAAGGATACGAGCG

Downstream 100 bases:

>100_bases
TGCGTCCTCGGGTTACGCTATGTTTTGCCCAAACCCTCGATGGTCGGGTGGCAGCCGTTGACGGCAGCTCGCAGTGGATC
AGCGGCCCCGAATCGCTCCG

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MDEWGIGHDRIILSGMQFIGYHGTRPEENRLGQRFVVDVAVQLDLQAAGVSDDLSQTVDYSQIHDRVREIVCGPPLKLTE
AVAERIAAAVLHDHPTIVAVAVRVTKPGVRLGETILAGSMVEIVRRR

Sequences:

>Translated_127_residues
MDEWGIGHDRIILSGMQFIGYHGTRPEENRLGQRFVVDVAVQLDLQAAGVSDDLSQTVDYSQIHDRVREIVCGPPLKLTE
AVAERIAAAVLHDHPTIVAVAVRVTKPGVRLGETILAGSMVEIVRRR
>Mature_127_residues
MDEWGIGHDRIILSGMQFIGYHGTRPEENRLGQRFVVDVAVQLDLQAAGVSDDLSQTVDYSQIHDRVREIVCGPPLKLTE
AVAERIAAAVLHDHPTIVAVAVRVTKPGVRLGETILAGSMVEIVRRR

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13975; Mature: 13975

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEWGIGHDRIILSGMQFIGYHGTRPEENRLGQRFVVDVAVQLDLQAAGVSDDLSQTVDY
CCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCHHHEEEHHHEEEHHCCCCCHHHHHHCCH
SQIHDRVREIVCGPPLKLTEAVAERIAAAVLHDHPTIVAVAVRVTKPGVRLGETILAGSM
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHH
VEIVRRR
HHHHHCC
>Mature Secondary Structure
MDEWGIGHDRIILSGMQFIGYHGTRPEENRLGQRFVVDVAVQLDLQAAGVSDDLSQTVDY
CCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCHHHEEEHHHEEEHHCCCCCHHHHHHCCH
SQIHDRVREIVCGPPLKLTEAVAERIAAAVLHDHPTIVAVAVRVTKPGVRLGETILAGSM
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHH
VEIVRRR
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]